8E4C
 
 | | IgM BCR fab truncated form | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, B-cell antigen receptor complex-associated protein alpha chain,Yellow fluorescent protein, B-cell antigen receptor complex-associated protein beta chain, ... | | Authors: | Dong, Y, Pi, X, Wu, H, Reth, M. | | Deposit date: | 2022-08-18 | | Release date: | 2022-11-16 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural principles of B cell antigen receptor assembly.
Nature, 612, 2022
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4N8V
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8FYJ
 | | Structure of HIV-1 BG505 SOSIP-HT2 in complex with two CD4 molecules (class I) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | Authors: | Fan, C, Dam, K.A, Bjorkman, P.J. | | Deposit date: | 2023-01-26 | | Release date: | 2023-10-18 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Intermediate conformations of CD4-bound HIV-1 Env heterotrimers.
Nature, 623, 2023
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8FYI
 | | Structure of HIV-1 BG505 SOSIP-HT1 in complex with one CD4 molecule | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(6-8)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Fan, C, Dam, K.A, Bjorkman, P.J. | | Deposit date: | 2023-01-26 | | Release date: | 2023-10-18 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Intermediate conformations of CD4-bound HIV-1 Env heterotrimers.
Nature, 623, 2023
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4OI7
 | | RAGE recognizes nucleic acids and promotes inflammatory responses to DNA | | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*CP*AP*CP*GP*TP*TP*CP*GP*TP*AP*GP*CP*AP*TP*CP*GP*TP*TP*GP*CP*AP*G)-3', 5'-D(*CP*TP*GP*CP*AP*AP*CP*GP*AP*TP*GP*CP*TP*AP*CP*GP*AP*AP*CP*GP*TP*G)-3', ... | | Authors: | Jin, T, Jiang, J, Xiao, T. | | Deposit date: | 2014-01-19 | | Release date: | 2014-04-30 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.104 Å) | | Cite: | RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
J.Exp.Med., 210, 2013
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8GRX
 | | APOE4 receptor in complex with APOE4 NTD | | Descriptor: | Apolipoprotein E, Leukocyte immunoglobulin-like receptor subfamily A member 6 | | Authors: | Zhou, J, Wang, Y, Huang, G, Shi, Y. | | Deposit date: | 2022-09-02 | | Release date: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | LilrB3 is a putative cell surface receptor of APOE4.
Cell Res., 33, 2023
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4OI8
 | | RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. | | Descriptor: | 5'-D(*CP*CP*AP*TP*GP*AP*CP*TP*GP*TP*AP*GP*GP*AP*AP*AP*CP*TP*CP*TP*AP*GP*A)-3', 5'-D(*CP*TP*CP*TP*AP*GP*AP*GP*TP*TP*TP*CP*CP*TP*AP*CP*AP*GP*TP*CP*AP*TP*G)-3', Advanced glycosylation end product-specific receptor | | Authors: | Jin, T, Jiang, J, Xiao, T. | | Deposit date: | 2014-01-19 | | Release date: | 2014-04-30 | | Method: | X-RAY DIFFRACTION (3.101 Å) | | Cite: | RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
J.Exp.Med., 210, 2013
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4OF5
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4OFV
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4PBV
 | | Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NT-3 growth factor receptor, Protein-tyrosine phosphatase CRYPalpha1 isoform, ... | | Authors: | Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R. | | Deposit date: | 2014-04-14 | | Release date: | 2014-11-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Nat Commun, 5, 2014
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4P2Y
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4PBW
 | | Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NT-3 growth factor receptor, Protein-tyrosine phosphatase CRYPalpha1 isoform | | Authors: | Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R. | | Deposit date: | 2014-04-14 | | Release date: | 2014-11-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Nat Commun, 5, 2014
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4P9H
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4Q6I
 | | Crystal structure of murine 2D5 Fab, a potent anti-CD4 HIV-1-neutralizing antibody in complex with CD4 | | Descriptor: | Heavy chain of murine 2D5 Fab, Light chain of murine 2D5 Fab, T-cell surface glycoprotein CD4 | | Authors: | Boyington, J.C, Nabel, G.J, Mascola, J.R. | | Deposit date: | 2014-04-22 | | Release date: | 2014-07-23 | | Method: | X-RAY DIFFRACTION (3.65 Å) | | Cite: | Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor.
Sci Transl Med, 6, 2014
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4R4H
 | | Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 Env gp120 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c, Heavy chain, ... | | Authors: | Mclellan, J, Acharya, P, Huang, C.-C, Kwong, P.D. | | Deposit date: | 2014-08-19 | | Release date: | 2014-09-17 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (4.28 Å) | | Cite: | Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
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4R2G
 | | Crystal Structure of PGT124 Fab bound to HIV-1 JRCSF gp120 core and to CD4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | Authors: | Garces, F, Wilson, I.A. | | Deposit date: | 2014-08-11 | | Release date: | 2014-10-08 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.283 Å) | | Cite: | Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies.
Cell(Cambridge,Mass.), 159, 2014
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3O4O
 | | Crystal structure of an Interleukin-1 receptor complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 beta, ... | | Authors: | Wang, X.Q, Wang, D.L, Zhang, S.Y, Li, L, Liu, X, Mei, K.R. | | Deposit date: | 2010-07-27 | | Release date: | 2010-09-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural insights into the assembly and activation of IL-1beta with its receptors
Nat.Immunol., 11, 2010
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3O2D
 | | Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody | | Descriptor: | T-cell surface glycoprotein CD4, ibalizumab heavy chain, ibalizumab light chain | | Authors: | Freeman, M.M, Seaman, M.S, Rits-Volloch, S, Hong, X, Ho, D.D, Chen, B. | | Deposit date: | 2010-07-22 | | Release date: | 2010-12-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Crystal Structure of HIV-1 Primary Receptor CD4 in Complex with a Potent Antiviral Antibody.
Structure, 18, 2010
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3O3U
 | | Crystal Structure of Human Receptor for Advanced Glycation Endproducts (RAGE) | | Descriptor: | Maltose-binding periplasmic protein, Advanced glycosylation end product-specific receptor, SULFATE ION, ... | | Authors: | Park, H, Boyington, J.C. | | Deposit date: | 2010-07-26 | | Release date: | 2010-10-13 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.497 Å) | | Cite: | The 1.5 A crystal structure of human receptor for advanced glycation endproducts (RAGE) ectodomains reveals unique features determining ligand binding.
J.Biol.Chem., 285, 2010
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3P40
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3OQ3
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3OL2
 | | Receptor-ligand structure of Human Semaphorin 4D with Plexin B1. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-B1, ... | | Authors: | Janssen, B.J.C, Robinson, R.A, Perez-Branguli, F, Bell, C.H, Mitchell, C.J, Siebold, C, Jones, E.Y. | | Deposit date: | 2010-08-25 | | Release date: | 2010-10-13 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Structural basis of semaphorin-plexin signalling.
Nature, 467, 2010
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3P2T
 | | Crystal Structure of Leukocyte Ig-like Receptor LILRB4 (ILT3/LIR-5/CD85k) | | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily B member 4, SULFATE ION | | Authors: | Chen, Y, Nam, G, Cheng, H, Zhang, J.H, Willcox, B.E, Gao, G.F. | | Deposit date: | 2010-10-04 | | Release date: | 2011-03-30 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.699 Å) | | Cite: | Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance
J.Biol.Chem., 286, 2011
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3P3Y
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3QS9
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