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1LUN	NMR Structure of the Itk SH2 domain, Pro287trans, energy minimized average structure Descriptor: Tyrosine-protein kinase ITK/TSK Authors: Mallis, R.J, Brazin, K.N, Fulton, D.B, Andreotti, A.H. Deposit date: 2002-05-22 Release date: 2002-11-27 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Structural characterization of a proline-driven conformational switch within the Itk SH2 domain Nat.Struct.Biol., 9, 2002
1M61	Crystal structure of the apo SH2 domains of ZAP-70 Descriptor: PHOSPHATE ION, TYROSINE-PROTEIN KINASE ZAP-70 Authors: Folmer, R.H.A, Geschwindner, S, Xue, Y. Deposit date: 2002-07-11 Release date: 2003-07-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure and NMR studies of the apo SH2 domains of ZAP-70: two bikes rather than a tandem Biochemistry, 41, 2002
1LUM	NMR Structure of the Itk SH2 domain, Pro287trans, 20 low energy structures Descriptor: Tyrosine-protein kinase ITK/TSK Authors: Mallis, R.J, Brazin, K.N, Fulton, D.B, Andreotti, A.H. Deposit date: 2002-05-22 Release date: 2002-11-27 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Structural characterization of a proline-driven conformational switch within the Itk SH2 domain Nat.Struct.Biol., 9, 2002
2KK6	Solution structure of sh2 domain of proto-oncogene tyrosine-protein kinase fer from homo sapiens, northeast structural genomics consortium (nesg) target hr3461d Descriptor: Proto-oncogene tyrosine-protein kinase FER Authors: Tang, Y, Wang, D, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) Deposit date: 2009-06-15 Release date: 2009-08-11 Last modified: 2020-02-26 Method: SOLUTION NMR Cite: Solution structure of sh2 domain of proto-oncogene tyrosine-protein kinase fer from homo sapiens, northeast structural genomics consortium (nesg) target hr3461d To be Published
2KNO	NMR Solution Structure of SH2 Domain of the Human Tensin Like C1 Domain Containing Phosphatase (TENC1) Descriptor: Tensin-like C1 domain-containing phosphatase Authors: Chen, L, Feng, R, Liu, C, Zhu, G. Deposit date: 2009-08-27 Release date: 2010-09-01 Last modified: 2011-07-13 Method: SOLUTION NMR Cite: NMR Solution Structure of SH2 Domain of the Human Tensin Like C1 Domain Containing Phosphatase (TENC1) To be Published
1MIL	TRANSFORMING PROTEIN Descriptor: SHC ADAPTOR PROTEIN Authors: Mikol, V. Deposit date: 1995-09-20 Release date: 1996-11-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of the SH2 domain from the adaptor protein SHC: a model for peptide binding based on X-ray and NMR data. J.Mol.Biol., 254, 1995
2L3T	Solution structure of tandem SH2 domain from Spt6 Descriptor: Transcription elongation factor SPT6 Authors: Liu, J, Zhang, J, Wu, J, Shi, Y. Deposit date: 2010-09-22 Release date: 2011-06-15 Last modified: 2011-07-13 Method: SOLUTION NMR Cite: Solution structure of the tandem SH2 domains from Spt6 and their binding to the phosphorylated RNA polymerase II C-terminal domain To be Published
2L4K	Water refined solution structure of the human Grb7-SH2 domain in complex with the 10 amino acid peptide pY1139 Descriptor: Growth factor receptor-bound protein 7, Receptor tyrosine-protein kinase erbB-2 Authors: Pias, S.C, Ivancic, M, Brescia, P.J, Johnson, D.L, Smith, D.E, Daly, R.J, Lyons, B.A. Deposit date: 2010-10-07 Release date: 2010-11-17 Last modified: 2012-10-03 Method: SOLUTION NMR Cite: Water-Refined Solution Structure of the Human Grb7-SH2 Domain in Complex with the erbB2 Receptor Peptide pY1139. Protein Pept.Lett., 19, 2012
1ZFP	GROWTH FACTOR RECEPTOR BINDING PROTEIN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PENTAPEPTIDE Descriptor: EPIDERMAL GROWTH FACTOR RECEPTOR-DERIVED PEPTIDE, GROWTH FACTOR RECEPTOR BINDING PROTEIN, ZINC ION Authors: Rahuel, J. Deposit date: 1998-03-26 Release date: 1999-03-30 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands. J.Mol.Biol., 279, 1998
1Z3K	Structural Insight into the Binding Diversity between the Tyr-Phosphorylated Human EphrinBs and Nck2 SH2 Domain Descriptor: Cytoplasmic protein NCK2 Authors: Ran, X, Song, J. Deposit date: 2005-03-14 Release date: 2005-03-29 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Structural insight into the binding diversity between the Tyr-phosphorylated human ephrinBs and Nck2 SH2 domain. J.Biol.Chem., 280, 2005
2AOA	Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain Descriptor: 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Growth factor receptor-bound protein 2 Authors: Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. Deposit date: 2005-08-12 Release date: 2005-10-04 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain. J.Mol.Biol., 353, 2005
2AUG	Crystal structure of the Grb14 SH2 domain Descriptor: Growth factor receptor-bound protein 14 Authors: Depetris, R.S, Hu, J, Gimpelevich, I, Holt, L.J, Daly, R.J, Hubbard, S.R. Deposit date: 2005-08-27 Release date: 2005-11-01 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for inhibition of the insulin receptor by the adaptor protein grb14. Mol.Cell, 20, 2005
2AOB	Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain Descriptor: 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, Growth factor receptor-bound protein 2 Authors: Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. Deposit date: 2005-08-12 Release date: 2005-10-04 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain. J.Mol.Biol., 353, 2005
2BBU	solution structure of mouse socs3 in complex with a phosphopeptide from the gp130 receptor Descriptor: GP130 PHOSPHOPEPTIDE, Suppressor of cytokine signaling 3 Authors: Babon, J.J, Yao, S, Norton, R.S. Deposit date: 2005-10-17 Release date: 2006-05-02 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability Mol.Cell, 22, 2006
2CIA	human nck2 sh2-domain in complex with a decaphosphopeptide from translocated intimin receptor (tir) of epec Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CYTOPLASMIC PROTEIN NCK2, ISOPROPYL ALCOHOL, ... Authors: Frese, S, Schubert, W.-D, Findeis, A.C, Marquardt, T, Roske, Y.S, Stradal, T.E.B, Heinz, D.W. Deposit date: 2006-03-17 Release date: 2006-04-24 Last modified: 2019-05-29 Method: X-RAY DIFFRACTION (1.45 Å) Cite: The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains. J.Biol.Chem., 281, 2006
2CI8	sh2 domain of human nck1 adaptor protein - uncomplexed Descriptor: CYTOPLASMIC PROTEIN NCK1, PENTAETHYLENE GLYCOL, SULFATE ION Authors: Frese, S, Schubert, W.-D, Findeis, A.C, Marquardt, T, Roske, Y.S, Stradal, T.E.B, Heinz, D.W. Deposit date: 2006-03-17 Release date: 2006-04-24 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains. J.Biol.Chem., 281, 2006
2CS0	Solution structure of the SH2 domain of human HSH2D protein Descriptor: Hematopoietic SH2 domain containing Authors: Kurosaki, C, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-20 Release date: 2005-11-20 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of the SH2 domain of human HSH2D protein To be published
2CI9	Nck1 SH2-domain in complex with a dodecaphosphopeptide from EPEC protein Tir Descriptor: CYTOPLASMIC PROTEIN NCK1, TRANSLOCATED INTIMIN RECEPTOR Authors: Frese, S, Schubert, W.-D, Findeis, A.C, Marquardt, T, Roske, Y.S, Stradal, T.E.B, Heinz, D.W. Deposit date: 2006-03-17 Release date: 2006-04-24 Last modified: 2019-05-15 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains. J.Biol.Chem., 281, 2006
2CRH	Solution structure of the SH2 domain of human proto-oncogene protein VAV1 Descriptor: Vav proto-oncogene Authors: Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-20 Release date: 2005-11-20 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of the SH2 domain of human proto-oncogene protein VAV1 to be published
2CR4	Solution structure of the SH2 domain of human SH3BP2 protein Descriptor: SH3 domain-binding protein 2 Authors: Hatta, R, Tomizawa, T, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-20 Release date: 2005-11-20 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of the SH2 domain of human SH3BP2 protein To be Published
2DM0	Solution structure of the SH2 domain of human Tyrosine-protein kinase TXK Descriptor: Tyrosine-protein kinase TXK Authors: Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-04-20 Release date: 2006-10-20 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of the SH2 domain of human Tyrosine-protein kinase TXK To be Published
2DX0	Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2 Descriptor: Phospholipase C, gamma 2, SULFATE ION Authors: Handa, N, Takagi, T, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-08-22 Release date: 2007-09-04 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2 To be Published
2DLZ	Solution structure of the SH2 domain of human protein vav-2 Descriptor: Protein vav-2 Authors: Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-04-20 Release date: 2007-04-03 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of the SH2 domain of human protein vav-2 To be Published
2DLY	Solution structure of the SH2 domain of murine Fyn-related kinase Descriptor: Fyn-related kinase Authors: Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-04-20 Release date: 2006-10-20 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of the SH2 domain of murine Fyn-related kinase To be Published
2DCR	Fully automated solution structure determination of the Fes SH2 domain Descriptor: Proto-oncogene tyrosine-protein kinase Fes/Fps Authors: Lopez-Mendez, B, Guntert, P. Deposit date: 2006-01-12 Release date: 2006-10-17 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Automated protein structure determination from NMR spectra J.AM.CHEM.SOC., 128, 2006

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