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Mine: Large structure entries

6WJD
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SA-LIKE STATE OF HUMAN 26S PROTEASOME WITH NON-CLEAVABLE M1-LINKED HEXAUBIQUITIN AND E3 UBIQUITIN LIGASE E6AP/UBE3A
Descriptor:26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 3, 26S proteasome non-ATPase regulatory subunit 12, ...
Authors:Chen, X., Walters, K.J.
Deposit date:2020-04-13
Release date:2020-08-05
Last modified:2020-08-26
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 2020
6WOT
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CRYO-EM STRUCTURE OF RECOMBINANT RABBIT RYANODINE RECEPTOR TYPE 1 MUTANT R164C IN COMPLEX WITH FKBP12.6
Descriptor:Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION
Authors:Iyer, K.A., Hu, Y., Kurebayashi, N., Murayama, T., Samso, M.
Deposit date:2020-04-25
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM
Sci Adv, 6, 2020
6WOU
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CRYO-EM STRUCTURE OF RECOMBINANT MOUSE RYANODINE RECEPTOR TYPE 2 MUTANT R176Q IN COMPLEX WITH FKBP12.6 IN NANODISC
Descriptor:Ryanodine receptor 2, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION
Authors:Iyer, K.A., Hu, Y., Kurebayashi, N., Murayama, T., Samso, M.
Deposit date:2020-04-25
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM
Sci Adv, 6, 2020
6WOV
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CRYO-EM STRUCTURE OF RECOMBINANT MOUSE RYANODINE RECEPTOR TYPE 2 WILD TYPE IN COMPLEX WITH FKBP12.6
Descriptor:Ryanodine receptor 2, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION
Authors:Iyer, K.A., Hu, Y., Nayak, A.R., Kurebayashi, N., Murayama, T., Samso, M.
Deposit date:2020-04-25
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM
Sci Adv, 6, 2020
6XQD
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH SARECYCLINE, UUC-MRNA, AND DEACYLATED P-SITE TRNA AT 2.80A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Batool, Z., Lomakin, I.B., Bunick, C.G., Polikanov, Y.S.
Deposit date:2020-07-09
Release date:2020-08-05
Last modified:2020-09-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 117, 2020
6XQE
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH SARECYCLINE, UAA-MRNA, AND DEACYLATED P-SITE TRNA AT 3.00A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Batool, Z., Lomakin, I.B., Bunick, C.G., Polikanov, Y.S.
Deposit date:2020-07-09
Release date:2020-08-05
Last modified:2020-09-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 117, 2020
6Y0K
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SULFITE OXIDASE FROM THERMUS THERMOPHILUS WITH COORDINATED PHOSPHATE
Descriptor:Putaitve sulfite oxidase, (MOLYBDOPTERIN-S,S)-OXO-MOLYBDENUM, GLYCEROL, ...
Authors:Djeghader, A., Soulimane, T.
Deposit date:2020-02-08
Release date:2020-08-05
Last modified:2020-09-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural evidence for a reaction intermediate mimic in the active site of a sulfite dehydrogenase.
Chem.Commun.(Camb.), 56, 2020
6YJQ
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CRYSTAL STRUCTURE OF UNLIGANDED MGAT5 (ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE V) LUMINAL DOMAIN WITH A LYS329-ILE345 LOOP TRUNCATION
Descriptor:Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A,Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, 1,2-ETHANEDIOL, SULFATE ION, ...
Authors:Wu, L., Darby, J.F., Gilio, A.K., Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
6YJR
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CRYSTAL STRUCTURE OF UNLIGANDED MGAT5 (ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE V) LUMINAL DOMAIN.
Descriptor:Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wu, L., Darby, J.F., Gilio, A.K., Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
6YJS
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CRYSTAL STRUCTURE OF MGAT5 (ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE V) LUMINAL DOMAIN WITH A LYS329-ILE345 LOOP TRUNCATION, IN COMPLEX WITH BIANTENNARY PENTASACCHARIDE M592
Descriptor:Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, 1,2-ETHANEDIOL, ...
Authors:Wu, L., Darby, J.F., Gilio, A.K., Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
6YJT
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CRYSTAL STRUCTURE OF MGAT5 (ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE V) LUMINAL DOMAIN WITH A LYS329-ILE345 LOOP TRUNCATION, IN COMPLEX WITH UDP
Descriptor:Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, URIDINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ...
Authors:Wu, L., Darby, J.F., Gilio, A.K., Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
6YJU
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CRYSTAL STRUCTURE OF MGAT5 (ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE V) LUMINAL DOMAIN WITH A LYS329-ILE345 LOOP TRUNCATION, IN COMPLEX WITH UDP AND BIANTENNARY PENTASACCHARIDE M592
Descriptor:Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, ...
Authors:Wu, L., Darby, J.F., Gilio, A.K., Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
6YJV
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CRYSTAL STRUCTURE OF UNLIGANDED MGAT5 (ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE V) LUMINAL DOMAIN WITH A LYS329-ILE345 LOOP TRUNCATION, IN COMPLEX WITH UDP-2-DEOXY-2-FLUOROGLUCOSE AND BIANTENNARY PENTASACCHARIDE M592
Descriptor:Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, ...
Authors:Wu, L., Darby, J.F., Gilio, A.K., Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
6ZB0
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C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 1-BENZYL-N-METHYL-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE
Descriptor:Bromodomain-containing protein 2, 1,2-ETHANEDIOL, ~{N}-methyl-2-oxidanylidene-1-(phenylmethyl)pyridine-3-carboxamide, ...
Authors:Chung, C.
Deposit date:2020-06-06
Release date:2020-08-05
Last modified:2020-09-23
Method:X-RAY DIFFRACTION (1.613 Å)
Cite:The Optimization of a Novel, Weak Bromo and Extra Terminal Domain (BET) Bromodomain Fragment Ligand to a Potent and Selective Second Bromodomain (BD2) Inhibitor.
J.Med.Chem., 63, 2020
6ZB1
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C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH GSK620
Descriptor:Bromodomain-containing protein 2, 1,2-ETHANEDIOL, ~{N}5-cyclopropyl-~{N}3-methyl-2-oxidanylidene-1-(phenylmethyl)pyridine-3,5-dicarboxamide
Authors:Chung, C.
Deposit date:2020-06-06
Release date:2020-08-05
Last modified:2020-09-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Optimization of a Novel, Weak Bromo and Extra Terminal Domain (BET) Bromodomain Fragment Ligand to a Potent and Selective Second Bromodomain (BD2) Inhibitor.
J.Med.Chem., 63, 2020
6ZB2
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C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH GSK549
Descriptor:Bromodomain-containing protein 2, 1,2-ETHANEDIOL, ~{N}5-cyclopropyl-1-(1~{H}-indol-4-ylmethyl)-~{N}3-methyl-2-oxidanylidene-pyridine-3,5-dicarboxamide, ...
Authors:Chung, C.
Deposit date:2020-06-06
Release date:2020-08-05
Last modified:2020-09-23
Method:X-RAY DIFFRACTION (2.282 Å)
Cite:The Optimization of a Novel, Weak Bromo and Extra Terminal Domain (BET) Bromodomain Fragment Ligand to a Potent and Selective Second Bromodomain (BD2) Inhibitor.
J.Med.Chem., 63, 2020
6ZB3
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N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH GSK620
Descriptor:Bromodomain-containing protein 4, 1,2-ETHANEDIOL, PENTAETHYLENE GLYCOL, ...
Authors:Chung, C.
Deposit date:2020-06-06
Release date:2020-08-05
Last modified:2020-09-23
Method:X-RAY DIFFRACTION (1.419 Å)
Cite:The Optimization of a Novel, Weak Bromo and Extra Terminal Domain (BET) Bromodomain Fragment Ligand to a Potent and Selective Second Bromodomain (BD2) Inhibitor.
J.Med.Chem., 63, 2020
6ZHC
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PROTAC6 MEDIATED COMPLEX OF VHL:ELOB:ELOC AND BCL-XL
Descriptor:von Hippel-Lindau disease tumor suppressor, Elongin-B, Elongin-C, ...
Authors:Chung, C.
Deposit date:2020-06-22
Release date:2020-08-05
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural insights into PROTAC-mediated degradation of Bcl-xL.
Acs Chem.Biol., 2020
6ZWV
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CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE PROTEINS ON INTACT VIRIONS: 3 CLOSED RBDS
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Ke, Z., Qu, K., Nakane, T., Xiong, X., Cortese, M., Zila, V., Scheres, S.H.W., Briggs, J.A.G.
Deposit date:2020-07-28
Release date:2020-08-05
Last modified:2020-09-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures and distributions of SARS-CoV-2 spike proteins on intact virions.
Nature, 2020
6LGL
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THE ATOMIC STRUCTURE OF VARICELLA-ZOSTER VIRUS A-CAPSID
Descriptor:Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ...
Authors:Zheng, Q., Li, S.
Deposit date:2019-12-05
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The atomic structure of varicella-zoster virus A-capsid
To Be Published
6LGN
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THE ATOMIC STRUCTURE OF VARICELLA ZOSTER VIRUS C-CAPSID
Descriptor:Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ...
Authors:Li, S., Zheng, Q.
Deposit date:2019-12-05
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:The atomic structure of varicella zoster virus C-capsid
To Be Published
6SKF
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CRYO-EM STRUCTURE OF T. KODAKARENSIS 70S RIBOSOME
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Matzov, D., Sas-Chen, A., Thomas, J.M., Santangelo, T., Meier, J.L., Schwartz, S., Shalev-Benami, M.
Deposit date:2019-08-15
Release date:2020-07-29
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Nature, 583, 2020
6SKG
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CRYO-EM STRUCTURE OF T. KODAKARENSIS 70S RIBOSOME IN TKNAT10 DELETED STRAIN
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Matzov, D., Sas-Chen, A., Thomas, J.M., Santangelo, T., Meier, J.L., Schwartz, S., Shalev-Benami, M.
Deposit date:2019-08-15
Release date:2020-07-29
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Nature, 583, 2020
6TH6
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CRYO-EM STRUCTURE OF T. KODAKARENSIS 70S RIBOSOME
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Matzov, D., Sas-Chen, A., Thomas, J.M., Santangelo, T., Meier, J.L., Schwartz, S., Shalev-Benami, M.
Deposit date:2019-11-18
Release date:2020-07-29
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Nature, 583, 2020
6TSL
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MARASMIUS OREADES AGGLUTININ (MOA) IN COMPLEX WITH THE TRUNCATED PVPRAHS SYNTHETIC SUBSTRATE
Descriptor:Agglutinin, PRO-VAL-PRO-ARG, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose, ...
Authors:Cordara, G., Manna, D., Krengel, U.
Deposit date:2019-12-20
Release date:2020-07-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of MOA in complex with a peptide fragment: a protease caught in flagranti
Curr Res Struct Biol, 2020
169117
PDB entries from 2020-09-23