PDB: 322 resultsInfo pagesStatus searchChemie searchBIRD

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8PBU	Mutant K1482M of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: del Cano-Ochoa, F, Ramon-Maiques, S. Deposit date: 2023-06-09 Release date: 2023-11-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
8PBE	Mutant K1556T of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... Authors: del Cano-Ochoa, F, Ramon-Maiques, S. Deposit date: 2023-06-09 Release date: 2023-11-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
8PBM	Mutant R1789Q of the dihydroorotase domain of human CAD protein bound to the substrate dihydroorotate Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: del Cano-Ochoa, F, Ramon-Maiques, S. Deposit date: 2023-06-09 Release date: 2023-11-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.28 Å) Cite: Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
8PBJ	Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate Descriptor: CAD protein, FORMIC ACID, GLYCEROL, ... Authors: del Cano-Ochoa, F, Ramon-Maiques, S. Deposit date: 2023-06-09 Release date: 2023-11-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
8PBK	Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: del Cano-Ochoa, F, Ramon-Maiques, S. Deposit date: 2023-06-09 Release date: 2023-11-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
8PBP	Mutant R1785C of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: del Cano-Ochoa, F, Ramon-Maiques, S. Deposit date: 2023-06-09 Release date: 2023-11-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
8PBQ	Mutant R1810Q of the dihydroorotase domain of human CAD protein bound to the substrates Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... Authors: del Cano-Ochoa, F, Ramon-Maiques, S. Deposit date: 2023-06-09 Release date: 2023-11-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
8PBI	Mutant R1617Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: del Cano-Ochoa, F, Ramon-Maiques, S. Deposit date: 2023-06-09 Release date: 2023-11-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023
6HFK	Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 6.5 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.459144 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFL	Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.0 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HG1	Hybrid dihydroorotase domain of human CAD with E. coli flexible loop in apo state Descriptor: CAD protein,Dihydroorotase,CAD protein, FORMIC ACID, ZINC ION Authors: Ramon-Maiques, S, Del Cano-Ochoa, F. Deposit date: 2018-08-22 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFE	Human dihydroorotase mutant F1563T apo structure Descriptor: CAD protein, FORMIC ACID, ZINC ION Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.47997439 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFU	Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.5 Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.3997103 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFF	Human dihydroorotase mutant F1563Y apo structure Descriptor: CAD protein, FORMIC ACID, ZINC ION Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.51000106 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFQ	Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.5 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.1454246 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFN	Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.5 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.44965148 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFH	Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.0 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.44871271 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFR	Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.0 Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.29949379 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HG2	Hybrid dihydroorotase domain of human CAD with E. coli flexible loop, bound to fluoroorotate Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Del Cano-Ochoa, F. Deposit date: 2018-08-22 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFP	Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.0 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.1982286 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HG3	Hybrid dihydroorotase domain of human CAD with E. coli flexible loop, bound to dihydroorotate Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Del Cano-Ochoa, F. Deposit date: 2018-08-22 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFI	Human dihydroorotase mutant F1563A apo structure Descriptor: CAD protein, FORMIC ACID, ZINC ION Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.45994723 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFJ	Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.5 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFS	Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 6.5 Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.34904516 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6JKU	Crystal structure of N-acetylglucosamine-6-phosphate deacetylase from Pasteurella Multocida Descriptor: 1,2-ETHANEDIOL, GLYCEROL, N-acetylglucosamine-6-phosphate deacetylase, ... Authors: Manjunath, L, Bose, S, Subramanian, R. Deposit date: 2019-03-01 Release date: 2020-03-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Quaternary variations in the structural assembly of N-acetylglucosamine-6-phosphate deacetylase from Pasteurella multocida. Proteins, 2020

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