Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5NI6
DownloadVisualize
BU of 5ni6 by Molmil
Crystal structure of human LTA4H mutant D375N in complex with LTA4
Descriptor: 5S-5,6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid, ACETIC ACID, Leukotriene A-4 hydrolase, ...
Authors:Stsiapanava, A.
Deposit date:2017-03-23
Release date:2017-08-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NIA
DownloadVisualize
BU of 5nia by Molmil
Crystal structure of human LTA4H mutant D375N in open conformation (crystal form I)
Descriptor: Leukotriene A-4 hydrolase, ZINC ION
Authors:Stsiapanava, A.
Deposit date:2017-03-23
Release date:2017-08-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.764 Å)
Cite:Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NID
DownloadVisualize
BU of 5nid by Molmil
Crystal structure of human LTA4H mutant D375N in open conformation (crystal form II)
Descriptor: Leukotriene A-4 hydrolase, ZINC ION
Authors:Stsiapanava, A.
Deposit date:2017-03-23
Release date:2017-08-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.568 Å)
Cite:Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NIE
DownloadVisualize
BU of 5nie by Molmil
Crystal structure of human LTA4H mutant R563A in open conformation
Descriptor: Leukotriene A-4 hydrolase, ZINC ION
Authors:Stsiapanava, A.
Deposit date:2017-03-23
Release date:2017-08-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5XM7
DownloadVisualize
BU of 5xm7 by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)-N-hydroxy-4-methylpentanamide
Descriptor: (2S)-4-methyl-N-[(1R)-2-(oxidanylamino)-2-oxidanylidene-1-phenyl-ethyl]-2-[(phenylmethyl)carbamoylamino]pentanamide, GLYCEROL, M1 family aminopeptidase, ...
Authors:Marapaka, A.K, Zhang, Y, Addlagatta, A.
Deposit date:2017-05-12
Release date:2018-06-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Development of peptidomimetic hydroxamates as PfA-M1 and PfA-M17 dual inhibitors: Biological evaluation and structural characterization by cocrystallization
Chin.Chem.Lett., 33, 2022
5Y19
DownloadVisualize
BU of 5y19 by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)- N-hydroxy-4-methylpentanamide.
Descriptor: (2S)-2-[[(2S,3R)-3-azanyl-2-oxidanyl-4-phenyl-butanoyl]amino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ...
Authors:Marapaka, A.K, Zhang, Y, Addlagatta, A.
Deposit date:2017-07-19
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)- N-hydroxy-4-methylpentanamide.
To Be Published
5Y1H
DownloadVisualize
BU of 5y1h by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,4-difluorobenzyl)ureido)-N-hydroxy-4-methylpentanamide
Descriptor: (2R)-2-[[2,4-bis(fluoranyl)phenyl]methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ...
Authors:Marapaka, A.K, Zhang, Y, Addlagatta, A.
Deposit date:2017-07-20
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,4-difluorobenzyl)ureido)-N-hydroxy-4-methylpentanamide
To Be Published
5Y1K
DownloadVisualize
BU of 5y1k by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2-chlorobenzyl)ureido)-N-hydroxy-4-methylpentanamide
Descriptor: (2S)-2-[(2-chlorophenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ...
Authors:Marapaka, A.K, Zhang, Y, Addlagatta, A.
Deposit date:2017-07-20
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Development of peptidomimetic hydroxamates as PfA-M1 and PfA-M17 dual inhibitors: Biological evaluation and structural characterization by cocrystallization
Chin.Chem.Lett., 33, 2022
5Y1Q
DownloadVisualize
BU of 5y1q by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(3-chlorobenzyl)ureido)-N-hydroxy-4-methylpentanamide
Descriptor: (2S)-2-[(3-chlorophenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:Marapaka, A.K, Zhang, Y, Addlagatta, A.
Deposit date:2017-07-21
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Development of peptidomimetic hydroxamates as PfA-M1 and PfA-M17 dual inhibitors: Biological evaluation and structural characterization by cocrystallization
Chin.Chem.Lett., 33, 2022
5Y1R
DownloadVisualize
BU of 5y1r by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-N-hydroxy-4-methyl-2-(3-( o-tolyl)ureido)pentanamide
Descriptor: (2R)-4-methyl-2-[(2-methylphenyl)carbamoylamino]-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ...
Authors:Marapaka, A.K, Zhang, Y, Addlagatta, A.
Deposit date:2017-07-21
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-N-hydroxy-4-methyl-2-(3-( o-tolyl)ureido)pentanamide
To Be Published
5Y1S
DownloadVisualize
BU of 5y1s by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(3,4-dimethylbenzyl)ureido)-N-hydroxy-4-methylpentanamide
Descriptor: (2R)-2-[(3,4-dimethylphenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, (2S)-2-[(3,4-dimethylphenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, ...
Authors:Marapaka, A.K, Zhang, Y, Addlagatta, A.
Deposit date:2017-07-21
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(3,4-dimethylbenzyl)ureido)-N-hydroxy-4-methylpentanamide
To Be Published
5Y1T
DownloadVisualize
BU of 5y1t by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,3-dimethylbenzyl)ureido)-N-hydroxy-4-methylpentanamide
Descriptor: (2S)-2-[(2,3-dimethylphenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ...
Authors:Marapaka, A.K, Zhang, Y, Addlagatta, A.
Deposit date:2017-07-21
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Development of peptidomimetic hydroxamates as PfA-M1 and PfA-M17 dual inhibitors: Biological evaluation and structural characterization by cocrystallization
Chin.Chem.Lett., 33, 2022
5Y1V
DownloadVisualize
BU of 5y1v by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)- N-hydroxy-4-methylpentanamide
Descriptor: (2R)-2-[(2,6-diethylphenyl)carbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ...
Authors:Marapaka, A.K, Zhang, Y, Addlagatta, A.
Deposit date:2017-07-21
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)- N-hydroxy-4-methylpentanamide
To Be Published
5Y1W
DownloadVisualize
BU of 5y1w by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N with Magnesium bound to active site Zinc
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:Marapaka, A.K, Addlagatta, A.
Deposit date:2017-07-21
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Crystal structure of Plasmodium falciparum aminopeptidase N with Magnesium bound to active site Zinc
To Be Published
5Y1X
DownloadVisualize
BU of 5y1x by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with actinonin
Descriptor: ACTINONIN, GLYCEROL, M1 family aminopeptidase, ...
Authors:Marapaka, A.K, Addlagatta, A.
Deposit date:2017-07-21
Release date:2018-08-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of Plasmodium falciparum aminopeptidase N in complex with actinonin
To Be Published
5Y3I
DownloadVisualize
BU of 5y3i by Molmil
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-N-hydroxy-4-methyl-2-(3-(3-methylbenzyl)ureido)pentanamide
Descriptor: (2R)-4-methyl-2-[(3-methylphenyl)methylcarbamoylamino]-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ...
Authors:Marapaka, A.K, Zhang, Y, Addlagatta, A.
Deposit date:2017-07-28
Release date:2018-08-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-N-hydroxy-4-methyl-2-(3-(3-methylbenzyl)ureido)pentanamide
To Be Published
5YO1
DownloadVisualize
BU of 5yo1 by Molmil
Structure of ePepN E298A mutant in complex with Puromycin
Descriptor: Aminopeptidase N, GLYCEROL, PUROMYCIN, ...
Authors:Ganji, R.J, Reddi, R, Marapaka, A.K, Addlagatta, A.
Deposit date:2017-10-26
Release date:2018-11-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis
Int.J.Biol.Macromol., 165, 2020
5YQ1
DownloadVisualize
BU of 5yq1 by Molmil
Crystal structure of E.coli aminopeptidase N in complex with O-Methyl-L-tyrosine
Descriptor: Aminopeptidase N, GLYCEROL, MALONATE ION, ...
Authors:Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A.
Deposit date:2017-11-04
Release date:2018-11-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structure of E.coli aminopeptidase N in complex with O-Methyl-L-tyrosine
To Be Published
5YQ2
DownloadVisualize
BU of 5yq2 by Molmil
Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside
Descriptor: (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL, Aminopeptidase N, GLYCEROL, ...
Authors:Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A.
Deposit date:2017-11-04
Release date:2018-11-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside
To Be Published
5YQB
DownloadVisualize
BU of 5yqb by Molmil
Crystal structure of E.coli aminopeptidase N in complex with Puromycin
Descriptor: (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL, Aminopeptidase N, GLYCEROL, ...
Authors:Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A.
Deposit date:2017-11-06
Release date:2018-11-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis
Int.J.Biol.Macromol., 165, 2020
5Z65
DownloadVisualize
BU of 5z65 by Molmil
Crystal structure of porcine aminopeptidase N ectodomain in functional form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Sun, Y.G, Li, R, Jiang, L.G, Qiao, S.L, Zhang, G.P.
Deposit date:2018-01-22
Release date:2019-01-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Characterization of the interaction between recombinant porcine aminopeptidase N and spike glycoprotein of porcine epidemic diarrhea virus.
Int. J. Biol. Macromol., 117, 2018
5ZI5
DownloadVisualize
BU of 5zi5 by Molmil
Crystal structure of Legionella pneumophila aminopeptidase A
Descriptor: Aminopeptidase N, ZINC ION
Authors:Marapaka, A.K, Addlagatta, A.
Deposit date:2018-03-14
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery, Structural and Biochemical Studies of a rare Glu/Asp Specific M1 Class Aminopeptidase from Legionella pneumophila
Int. J. Biol. Macromol., 120, 2018
5ZI7
DownloadVisualize
BU of 5zi7 by Molmil
Crystal structure of Legionella pneumophila aminopeptidase A in complex with glutamic acid
Descriptor: Aminopeptidase N, GLUTAMIC ACID
Authors:Marapaka, A.K, Addlagatta, A.
Deposit date:2018-03-14
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Discovery, Structural and Biochemical Studies of a rare Glu/Asp Specific M1 Class Aminopeptidase from Legionella pneumophila
Int. J. Biol. Macromol., 120, 2018
5ZIE
DownloadVisualize
BU of 5zie by Molmil
Crystal structure of Legionella pneumophila aminopeptidase A in complex with aspartic acid
Descriptor: ASPARTIC ACID, Aminopeptidase N
Authors:Marapaka, A.K, Addlagatta, A.
Deposit date:2018-03-14
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery, Structural and Biochemical Studies of a rare Glu/Asp Specific M1 Class Aminopeptidase from Legionella pneumophila
Int. J. Biol. Macromol., 120, 2018
6A8Z
DownloadVisualize
BU of 6a8z by Molmil
Crystal structure of M1 zinc metallopeptidase from Deinococcus radiodurans
Descriptor: SODIUM ION, TYROSINE, ZINC ION, ...
Authors:Agrawal, R, Kumar, A, Makde, R.D.
Deposit date:2018-07-11
Release date:2019-07-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.045 Å)
Cite:Two-domain aminopeptidase of M1 family: Structural features for substrate binding and gating in absence of C-terminal domain.
J.Struct.Biol., 208, 2019

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon