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1N99
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CRYSTAL STRUCTURE OF THE PDZ TANDEM OF HUMAN SYNTENIN
Descriptor: Syntenin 1
Authors:Kang, B.S, Cooper, D.R, Jelen, F, Devedjiev, Y, Derewenda, U, Dauter, Z, Otlewski, J, Derewenda, Z.S.
Deposit date:2002-11-22
Release date:2003-04-15
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:PDZ Tandem of Human Syntenin: Crystal Structure and Functional Properties
Structure, 11, 2003
1N7F
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BU of 1n7f by Molmil
Crystal structure of the sixth PDZ domain of GRIP1 in complex with liprin C-terminal peptide
Descriptor: 8-mer peptide from interacting protein (liprin), AMPA receptor interacting protein GRIP
Authors:Im, Y.J, Park, S.H, Rho, S.H, Lee, J.H, Kang, G.B, Sheng, M, Kim, E, Eom, S.H.
Deposit date:2002-11-14
Release date:2003-08-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of GRIP1 PDZ6-peptide complex reveals the structural basis for class II PDZ target recognition and PDZ domain-mediated multimerization
J.BIOL.CHEM., 278, 2003
1OBY
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Crystal structure of the complex of PDZ2 of syntenin with a syndecan-4 peptide.
Descriptor: SULFATE ION, SYNDECAN-4, SYNTENIN 1
Authors:Kang, B.S, Cooper, D.R, Devedjiev, Y, Derewenda, U, Derewenda, Z.S.
Deposit date:2003-01-31
Release date:2003-07-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular Roots of Degenerate Specificity in Syntenin'S Pdz2 Domain: Reassessment of the Pdz Recognition Paradigm
Structure, 11, 2003
3SFJ
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BU of 3sfj by Molmil
Crystal Structure of Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to iCAL36 inhibitor peptide
Descriptor: Tax1-binding protein 3, decameric peptide iCAL36
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2011-06-13
Release date:2012-12-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:A CAL Inhibitor with Single-PDZ Specificity Rescues deltaF508-CFTR
To be Published
3SHU
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Crystal structure of ZO-1 PDZ3
Descriptor: Tight junction protein ZO-1
Authors:Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M.
Deposit date:2011-06-17
Release date:2011-09-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
3GSL
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Crystal structure of PSD-95 tandem PDZ domains 1 and 2
Descriptor: Disks large homolog 4
Authors:Sainlos, M, Olivier, N.B, Imperiali, B.
Deposit date:2009-03-27
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Biomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilization.
Nat.Chem.Biol., 7, 2011
3HPM
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Oxidized dimeric PICK1 PDZ C46G mutant in complex with the carboxyl tail peptide of GluR2
Descriptor: PRKCA-binding protein,9-mer peptide of THE GLUR2 SUBUNIT
Authors:Yu, J, Shi, Y, Zhang, M.
Deposit date:2009-06-04
Release date:2010-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain.
Biochemistry, 49, 2010
3I4W
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Crystal Structure of the third PDZ domain of PSD-95
Descriptor: ACETATE ION, Disks large homolog 4
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2009-07-03
Release date:2010-04-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Novel conformational aspects of the third PDZ domain of the neuronal post-synaptic density-95 protein revealed from two 1.4A X-ray structures
J.Struct.Biol., 170, 2010
3HPK
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Oxidized dimeric PICK1 PDZ in complex with the carboxyl tail peptide of GluR2
Descriptor: GLYCEROL, PRKCA-binding protein,9-mer peptide of THE GLUR2 SUBUNIT
Authors:Yu, J, Shi, Y, Zhang, M.
Deposit date:2009-06-04
Release date:2010-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain.
Biochemistry, 49, 2010
3ID2
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Crystal Structure of RseP PDZ2 domain
Descriptor: IODIDE ION, Regulator of sigma E protease
Authors:Li, X, Wang, B, Feng, L, Wang, J, Shi, Y.
Deposit date:2009-07-20
Release date:2009-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.089 Å)
Cite:Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
3ID4
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Crystal Structure of RseP PDZ2 domain fused GKASPV peptide
Descriptor: Regulator of sigma E protease
Authors:Li, X, Wang, B, Feng, L, Wang, J, Shi, Y.
Deposit date:2009-07-20
Release date:2009-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.604 Å)
Cite:Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
3ID3
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Crystal Structure of RseP PDZ2 I304A domain
Descriptor: Regulator of sigma E protease
Authors:Li, X, Wang, B, Feng, L, Wang, J, Shi, Y.
Deposit date:2009-07-20
Release date:2009-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
3JXT
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Crystal structure of the third PDZ domain of SAP-102 in complex with a fluorogenic peptide-based ligand
Descriptor: ACETATE ION, Disks large homolog 3, Voltage-dependent calcium channel gamma-2 subunit
Authors:Sainlos, M, Olivier, N.B, Imperiali, B.
Deposit date:2009-09-21
Release date:2010-09-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Caged mono- and divalent ligands for light-assisted disruption of PDZ domain-mediated interactions.
J.Am.Chem.Soc., 135, 2013
3K82
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Crystal Structure of the third PDZ domain of PSD-95
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Disks large homolog 4, GLYCEROL, ...
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2009-10-13
Release date:2010-04-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Novel conformational aspects of the third PDZ domain of the neuronal post-synaptic density-95 protein revealed from two 1.4A X-ray structures
J.Struct.Biol., 170, 2010
3KZD
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BU of 3kzd by Molmil
Crystal Structure of Free T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain
Descriptor: T-lymphoma invasion and metastasis-inducing protein 1
Authors:Shepherd, T.R, Fuentes, E.J.
Deposit date:2009-12-08
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion.
J.Mol.Biol., 398, 2010
3KZE
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Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in Complex With SSRKEYYA Peptide
Descriptor: Synthetic Peptide, T-lymphoma invasion and metastasis-inducing protein 1
Authors:Shepherd, T.R, Fuentes, E.J.
Deposit date:2009-12-08
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion.
J.Mol.Biol., 398, 2010
3LNX
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Second PDZ domain from human PTP1E
Descriptor: IODIDE ION, THIOCYANATE ION, Tyrosine-protein phosphatase non-receptor type 13
Authors:Zhang, J, Chang, A, Ke, H, Phillips Jr, G.N, Lee, A.L, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2010-02-03
Release date:2010-02-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.642 Å)
Cite:Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.
Biochemistry, 49, 2010
3LNY
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Second PDZ domain from human PTP1E in complex with RA-GEF2 peptide
Descriptor: Rap guanine nucleotide exchange factor 6, SULFATE ION, THIOCYANATE ION, ...
Authors:Zhang, J, Chang, A, Ke, H, Phillips Jr, G.N, Lee, A.L, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2010-02-03
Release date:2010-03-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.
Biochemistry, 49, 2010
1NTE
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CRYSTAL STRUCTURE ANALYSIS OF THE SECOND PDZ DOMAIN OF SYNTENIN
Descriptor: OXYGEN ATOM, Syntenin 1
Authors:Kang, B.S, Cooper, D.R, Devedjiev, Y, Derewenda, U, Derewenda, Z.S.
Deposit date:2003-01-29
Release date:2003-07-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Molecular roots of degenerate specificity in syntenin's PDZ2 domain: reassessment of the PDZ recognition paradigm.
Structure, 11, 2003
1OBX
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Crystal structure of the complex of PDZ2 of syntenin with an interleukin 5 receptor alpha peptide.
Descriptor: COBALT (II) ION, INTERLEUKIN 5 RECEPTOR ALPHA, SULFATE ION, ...
Authors:Kang, B.S, Cooper, D.R, Devedjiev, Y, Derewenda, U, Derewenda, Z.S.
Deposit date:2003-01-31
Release date:2003-07-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Molecular Roots of Degenerate Specificity in Syntenin'S Pdz2 Domain: Reassessment of the Pdz Recognition Paradigm
Structure, 11, 2003
1OBZ
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Crystal structure of the complex of the PDZ tandem of syntenin with an interleukin 5 receptor alpha peptide.
Descriptor: ACETATE ION, INTERLEUKIN 5 RECEPTOR ALPHA, SYNTENIN 1
Authors:Kang, B.S, Cooper, D.R, Devedjiev, Y, Derewenda, U, Derewenda, Z.S.
Deposit date:2003-01-31
Release date:2003-07-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Roots of Degenerate Specificity in Syntenin'S Pdz2 Domain: Reassessment of the Pdz Recognition Paradigm
Structure, 11, 2003
1OZI
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The alternatively spliced PDZ2 domain of PTP-BL
Descriptor: protein tyrosine phosphatase
Authors:Walma, T, Aelen, J, Oostendorp, M, van den Berk, L, Hendriks, W, Vuister, G.W.
Deposit date:2003-04-09
Release date:2004-01-27
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:A Closed Binding Pocket and Global Destabilization Modify the Binding Properties of an Alternatively Spliced Form of the Second PDZ Domain of PTP-BL.
Structure, 12, 2004
1PDR
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CRYSTAL STRUCTURE OF THE THIRD PDZ DOMAIN FROM THE HUMAN HOMOLOG OF DISCS LARGE PROTEIN
Descriptor: HUMAN DISCS LARGE PROTEIN
Authors:Cabral, J.M, Liddington, R.
Deposit date:1996-07-26
Release date:1997-07-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a PDZ domain.
Nature, 382, 1996
1Q7X
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Solution structure of the alternatively spliced PDZ2 domain (PDZ2b) of PTP-Bas (hPTP1E)
Descriptor: PDZ2b domain of PTP-Bas (hPTP1E)
Authors:Kachel, N, Erdmann, K.S, Kremer, W, Wolff, P, Gronwald, W, Heumann, R, Kalbitzer, H.R, Structural Proteomics in Europe (SPINE)
Deposit date:2003-08-20
Release date:2003-12-02
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure determination and ligand interactions of the PDZ2b domain of PTP-Bas (hPTP1E): Splicing induced modulation of ligand specificity.
J.Mol.Biol., 334, 2003
1QAU
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UNEXPECTED MODES OF PDZ DOMAIN SCAFFOLDING REVEALED BY STRUCTURE OF NNOS-SYNTROPHIN COMPLEX
Descriptor: NEURONAL NITRIC OXIDE SYNTHASE (RESIDUES 1-130)
Authors:Hillier, B.J, Christopherson, K.S, Prehoda, K.E, Bredt, D.S, Lim, W.A.
Deposit date:1999-03-29
Release date:1999-05-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex.
Science, 284, 1999

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