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1YED
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BU of 1yed by Molmil
STRUCTURE OF A CATALYTIC ANTIBODY IGG2A FAB FRAGMENT (D2.4)
Descriptor: 4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE, IGG1 FAB FRAGMENT (D.2.4)
Authors:Golinelli-Pimpaneau, B, Knossow, M.
Deposit date:1997-04-15
Release date:1997-10-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural convergence in the active sites of a family of catalytic antibodies.
Science, 275, 1997
1YEG
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BU of 1yeg by Molmil
STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH REACTION PRODUCT
Descriptor: ACETATE ION, IGG2A FAB FRAGMENT, PARANITROBENZYL ALCOHOL, ...
Authors:Gigant, B, Knossow, M.
Deposit date:1997-05-29
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.
Proc.Natl.Acad.Sci.USA, 94, 1997
1YEE
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BU of 1yee by Molmil
STRUCTURE OF A CATALYTIC ANTIBODY, IGG2A FAB FRAGMENT (D2.5)
Descriptor: 4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE, IGG2A FAB FRAGMENT (D2.5)
Authors:Golinelli-Pimpaneau, B, Knossow, M.
Deposit date:1997-04-15
Release date:1997-10-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural convergence in the active sites of a family of catalytic antibodies.
Science, 275, 1997
1YEF
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BU of 1yef by Molmil
STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH SUBSTRATE ANALOGUE
Descriptor: IGG2A FAB FRAGMENT, PARA-NITROBENZYL GLUTARYL GLYCINIC ACID, ZINC ION
Authors:Gigant, B, Knossow, M.
Deposit date:1997-05-29
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.
Proc.Natl.Acad.Sci.USA, 94, 1997
1YEC
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BU of 1yec by Molmil
STRUCTURE OF A CATALYTIC ANTIBODY IGG2A FAB FRAGMENT (D2.3)
Descriptor: 4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE, IGG2A FAB FRAGMENT (D2.3), ZINC ION
Authors:Golinelli-Pimpaneau, B, Knossow, M.
Deposit date:1997-04-15
Release date:1997-10-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural convergence in the active sites of a family of catalytic antibodies.
Science, 275, 1997
1YEH
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BU of 1yeh by Molmil
STRUCTURE OF IGG2A FAB FRAGMENT
Descriptor: FAB FRAGMENT, ZINC ION
Authors:Gigant, B, Knossow, M.
Deposit date:1997-05-29
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.
Proc.Natl.Acad.Sci.USA, 94, 1997
2F8O
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BU of 2f8o by Molmil
A Native to Amyloidogenic Transition Regulated by a Backbone Trigger
Descriptor: Beta-2-microglobulin
Authors:Eakin, C.M, Berman, A.J, Miranker, A.D.
Deposit date:2005-12-02
Release date:2006-02-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A native to amyloidogenic transition regulated by a backbone trigger.
Nat.Struct.Mol.Biol., 13, 2006
7LFN
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BU of 7lfn by Molmil
Structure of Hyperglycosylated Human IgG1 Fc (Fc267_329)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 Fc (Fc267_329), alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Fields, J.K, Sundberg, E.J.
Deposit date:2021-01-17
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions
To Be Published
7LF9
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BU of 7lf9 by Molmil
Structure of Hyperglycosylated Human IgG1 Fc (Fc329)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 Fc (Fc329), ...
Authors:Fields, J.K, Sundberg, E.J.
Deposit date:2021-01-15
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions
To Be Published
7LBL
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BU of 7lbl by Molmil
Structure of Human IgG1 Fc
Descriptor: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Fields, J.K, Sundberg, E.J.
Deposit date:2021-01-08
Release date:2021-01-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions
To Be Published
7LF5
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BU of 7lf5 by Molmil
Structure of Hyperglycosylated Human IgG1 Fc (Fc267)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 Fc (Fc267), alpha-L-fucopyranose, ...
Authors:Fields, J.K, Sundberg, E.J.
Deposit date:2021-01-15
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions
To Be Published
2F19
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BU of 2f19 by Molmil
THREE-DIMENSIONAL STRUCTURE OF TWO CRYSTAL FORMS OF FAB R19.9, FROM A MONOCLONAL ANTI-ARSONATE ANTIBODY
Descriptor: IGG2B-KAPPA R19.9 FAB (HEAVY CHAIN), IGG2B-KAPPA R19.9 FAB (LIGHT CHAIN)
Authors:Lascombe, M.B, Alzari, P.M, Poljak, R.J, Nisonoff, A.
Deposit date:1992-05-27
Release date:1992-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Three-dimensional structure of two crystal forms of FabR19.9 from a monoclonal anti-arsonate antibody.
Proc.Natl.Acad.Sci.USA, 89, 1992
7LUS
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BU of 7lus by Molmil
IgG2 Fc Charge Pair Mutation version 1 (CPMv1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant gamma 2
Authors:Sudom, A, Whittington, D, Garces, F, Wang, Z.
Deposit date:2021-02-23
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Next generation Fc scaffold for multispecific antibodies.
Iscience, 24, 2021
7LUR
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BU of 7lur by Molmil
Stable Effector Functionless 2 (SEFL2) IgG1 Fc Scaffold Bound to a Minimized Version of the B-domain (Mini-Z) from Protein A Called Z34C
Descriptor: Immunoglobulin heavy constant gamma 1, Mini Z domain
Authors:Sudom, A, Garces, F, Wang, Z.
Deposit date:2021-02-23
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Next generation Fc scaffold for multispecific antibodies.
Iscience, 24, 2021
7MXI
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BU of 7mxi by Molmil
IgE-Fc in complex with DARPins E2_79 and E3_53
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-IgE Inhibitor E2_79, DARPin E3_53, ...
Authors:Pennington, L.F, Jardetzky, T.J.
Deposit date:2021-05-19
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-guided design of ultrapotent disruptive IgE inhibitors to rapidly terminate acute allergic reactions.
J.Allergy Clin.Immunol., 148, 2021
7NUI
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BU of 7nui by Molmil
Crystal structure of HLA-B*08:01 in complex with ELRSRYWAI viral peptide
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Mavridis, G, Giastas, P, Mpakali, A.
Deposit date:2021-03-12
Release date:2021-04-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of HLA-B*08:01 in complex with ELRSRYWAI viral peptide
To Be Published
7NMO
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BU of 7nmo by Molmil
Crystal structure of beta-2-microglobulin D76A mutant
Descriptor: Beta-2-microglobulin
Authors:Guthertz, N.
Deposit date:2021-02-23
Release date:2022-08-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NN5
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BU of 7nn5 by Molmil
Crystal structure of beta-2-microglobulin D76K mutant
Descriptor: Beta-2-microglobulin
Authors:Guthertz, N.
Deposit date:2021-02-24
Release date:2022-08-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.242 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMR
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BU of 7nmr by Molmil
Crystal structure of beta-2-microglobulin D76S mutant
Descriptor: Beta-2-microglobulin, GLYCEROL
Authors:Guthertz, N.
Deposit date:2021-02-23
Release date:2022-08-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMY
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BU of 7nmy by Molmil
Crystal structure of beta-2-microglobulin D76Y mutant
Descriptor: Beta-2-microglobulin
Authors:Guthertz, N.
Deposit date:2021-02-23
Release date:2022-08-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMC
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BU of 7nmc by Molmil
Crystal structure of beta-2-microglobulin D76E mutant
Descriptor: Beta-2-microglobulin, GLYCEROL, TRIETHYLENE GLYCOL
Authors:Guthertz, N.
Deposit date:2021-02-23
Release date:2022-08-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMV
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BU of 7nmv by Molmil
Crystal structure of beta-2-microglobulin D76Q mutant
Descriptor: Beta-2-microglobulin
Authors:Guthertz, N.
Deposit date:2021-02-23
Release date:2022-08-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMT
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BU of 7nmt by Molmil
Crystal structure of beta-2-microglobulin D76G mutant
Descriptor: Beta-2-microglobulin
Authors:Guthertz, N.
Deposit date:2021-02-23
Release date:2022-08-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
2J6E
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BU of 2j6e by Molmil
Crystal Structure of an Autoimmune Complex between a Human IgM Rheumatoid Factor and IgG1 Fc reveals a Novel Fc Epitope and Evidence for Affinity Maturation
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CACODYLATE ION, ...
Authors:Duquerroy, S, Stura, E.A, Bressanelli, S, Browne, H, Beale, D, Hamon, M, Casali, P, Vaney, M.C, Rey, F.A, Sutton, B.J, Taussig, M.J.
Deposit date:2006-09-28
Release date:2007-04-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a human autoimmune complex between IgM rheumatoid factor RF61 and IgG1 Fc reveals a novel epitope and evidence for affinity maturation.
J.Mol.Biol., 368, 2007
2JB6
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BU of 2jb6 by Molmil
Fab fragment in complex with small molecule hapten, crystal form-2
Descriptor: 2-{(1E,3Z,5E,7E)-7-[3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-1,3-DIHYDRO-2H-INDOL-2-YLIDENE]-4-METHYLHEPTA-1,3,5-TRIEN-1-YL}-3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-3H-INDOLIUM, FAB FRAGMENT MOR03268 HEAVY CHAIN, FAB FRAGMENT MOR03268 LIGHT CHAIN
Authors:Hillig, R.C, Baesler, S, Malawski, G, Badock, V, Bahr, I, Schirner, M, Licha, K.
Deposit date:2006-12-03
Release date:2008-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Fab Mor03268 Triggers Absorption Shift of a Diagnostic Dye Via Packaging in a Solvent-Shielded Fab Dimer Interface
J.Mol.Biol., 377, 2008

217705

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