PDB: 195 resultsInfo pagesStatus searchChemie searchBIRD

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1ZZB	Crystal Structure of CoII HppE in Complex with Substrate Descriptor: (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, COBALT (II) ION, Hydroxypropylphosphonic Acid Epoxidase Authors: Higgins, L.J, Yan, F, Liu, P, Liu, H.W, Drennan, C.L. Deposit date: 2005-06-13 Release date: 2005-07-26 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme Nature, 437, 2005
1ZZ8	Crystal Structure of FeII HppE in Complex with Substrate Form 2 Descriptor: (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, FE (II) ION, Hydroxypropylphosphonic Acid Epoxidase Authors: Higgins, L.J, Yan, F, Liu, P, Liu, H.W, Drennan, C.L. Deposit date: 2005-06-13 Release date: 2005-07-26 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme Nature, 437, 2005
4MCT	P. vulgaris HIGBA structure, crystal form 1 Descriptor: Antidote protein, Killer protein Authors: Schureck, M.A, Maehigashi, T, Dunham, C.M. Deposit date: 2013-08-21 Release date: 2013-12-11 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure of the Proteus vulgaris HigB-(HigA)2-HigB Toxin-Antitoxin Complex. J.Biol.Chem., 289, 2014
4MCX	P. vulgaris HIGBA structure, crystal form 2 Descriptor: Antidote protein, Killer protein Authors: Schureck, M.A, Maehigashi, T, Dunham, C.M. Deposit date: 2013-08-21 Release date: 2013-12-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of the Proteus vulgaris HigB-(HigA)2-HigB Toxin-Antitoxin Complex. J.Biol.Chem., 289, 2014
3HZI	Structure of mdt protein Descriptor: 5'-D(*DAP*DCP*DTP*DAP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DTP*DAP*DG)-3', ADENOSINE-5'-TRIPHOSPHATE, HTH-type transcriptional regulator hipB, ... Authors: Schumacher, M.A. Deposit date: 2009-06-23 Release date: 2009-07-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.98 Å) Cite: Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB. Science, 323, 2009
3IVP	The structure of a possible transposon-related DNA-binding protein from Clostridium difficile 630. Descriptor: Putative transposon-related DNA-binding protein, TETRAETHYLENE GLYCOL Authors: Tan, K, Marshall, N, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2009-09-01 Release date: 2009-09-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.02 Å) Cite: The structure of a possible transposon-related DNA-binding protein from Clostridium difficile 630. To be Published
1RIO	Structure of bacteriophage lambda cI-NTD in complex with sigma-region4 of Thermus aquaticus bound to DNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 27-MER, CALCIUM ION, ... Authors: Jain, D, Nickels, B.E, Sun, L, Hochschild, A, Darst, S.A. Deposit date: 2003-11-17 Release date: 2004-01-27 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of a ternary transcription activation complex. Mol.Cell, 13, 2004
4PU3	Shewanella oneidensis MR-1 Toxin Antitoxin System HipA, HipB and its operator DNA complex (space group P212121) Descriptor: Operator DNA, Toxin-antitoxin system antidote transcriptional repressor Xre family, Toxin-antitoxin system toxin HipA family Authors: Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S. Deposit date: 2014-03-12 Release date: 2014-08-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.39 Å) Cite: The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence. Nucleic Acids Res., 42, 2014
4PU4	Shewanella oneidensis MR-1 Toxin Antitoxin System HipA, HipB and its operator DNA complex (space group P21) Descriptor: Operator DNA, Toxin-antitoxin system antidote transcriptional repressor Xre family, Toxin-antitoxin system toxin HipA family Authors: Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S. Deposit date: 2014-03-12 Release date: 2014-08-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.786 Å) Cite: The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence. Nucleic Acids Res., 42, 2014
3SCF	Fe(II)-HppE with S-HPP and NO Descriptor: (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, Epoxidase, FE (II) ION, ... Authors: Drennan, C.L. Deposit date: 2011-06-07 Release date: 2011-07-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis. J.Am.Chem.Soc., 133, 2011
3U3W	Crystal Structure of Bacillus thuringiensis PlcR in complex with the peptide PapR7 and DNA Descriptor: 5'-D(P*AP*TP*AP*TP*GP*AP*AP*AP*TP*AP*TP*TP*GP*CP*AP*TP*AP*G)-3', 5'-D(P*CP*TP*AP*TP*GP*CP*AP*AP*TP*AP*TP*TP*TP*CP*AP*TP*AP*T)-3', C-terminus heptapeptide from PapR protein, ... Authors: Grenha, R, Slamti, L, Bouillaut, L, Lereclus, D, Nessler, S. Deposit date: 2011-10-06 Release date: 2013-01-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for the activation mechanism of the PlcR virulence regulator by the quorum-sensing signal peptide PapR. Proc.Natl.Acad.Sci.USA, 110, 2013
3DNV	MDT Protein Descriptor: DNA (5'-D(*DAP*DCP*DTP*DAP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DTP*DAP*DG)-3'), HTH-type transcriptional regulator hipB, Protein hipA, ... Authors: schumacher, M.A. Deposit date: 2008-07-02 Release date: 2009-01-27 Last modified: 2023-04-05 Method: X-RAY DIFFRACTION (2.68 Å) Cite: Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB. Science, 323, 2009
3WOA	Crystal structure of lambda repressor (1-45) fused with maltose-binding protein Descriptor: Repressor protein CI, Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose Authors: Hanazono, Y, Takeda, K, Miki, K. Deposit date: 2013-12-25 Release date: 2015-04-29 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Co-translational folding of alpha-helical proteins: structural studies of intermediate-length variants of the lambda repressor. FEBS Open Bio, 8, 2018
3ZKC	Crystal structure of the master regulator for biofilm formation SinR in complex with DNA. Descriptor: 5'-D(*AP*AP*AP*GP*TP*TP*CP*TP*CP*TP*TP*TP*AP*GP *AP*GP*AP*AP*CP*AP*AP)-3', 5'-D(*AP*TP*TP*GP*TP*TP*CP*TP*CP*TP*AP*AP*AP*GP *AP*GP*AP*AP*CP*TP*TP)-3', HTH-TYPE TRANSCRIPTIONAL REGULATOR SINR Authors: Newman, J.A, Rodrigues, C, Lewis, R.J. Deposit date: 2013-01-22 Release date: 2013-03-06 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Molecular Basis of the Activity of Sinr, the Master Regulator of Biofilm Formation in Bacillus Subtilis. J.Biol.Chem., 288, 2013
6HPB	Crystal structure of the E.coli HicAB toxin-antitoxin complex Descriptor: Antitoxin HicB, SULFATE ION, mRNA interferase toxin HicA Authors: Manav, M.C, Brodersen, D.E. Deposit date: 2018-09-20 Release date: 2019-09-18 Last modified: 2019-11-13 Method: X-RAY DIFFRACTION (2.28 Å) Cite: The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain. Structure, 27, 2019
4FSC	Crystal Structure of Bacillus thuringiensis PlcR in its apo form Descriptor: Transcriptional activator PlcR protein Authors: Grenha, R, Slamti, L, Bouillaut, L, Lereclus, D, Nessler, S. Deposit date: 2012-06-27 Release date: 2013-03-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.65 Å) Cite: Structural basis for the activation mechanism of the PlcR virulence regulator by the quorum-sensing signal peptide PapR. Proc.Natl.Acad.Sci.USA, 110, 2013
6KML	2.09 Angstrom resolution crystal structure of tetrameric HigBA toxin-antitoxin complex from E.coli Descriptor: Antitoxin HigA, mRNA interferase toxin HigB Authors: Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M. Deposit date: 2019-07-31 Release date: 2020-11-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.095 Å) Cite: 2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin. Biochem.J., 477, 2020
6KMQ	2.3 Angstrom resolution structure of dimeric HigBA toxin-antitoxin complex from E. coli Descriptor: Antitoxin HigA, mRNA interferase toxin HigB Authors: Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M. Deposit date: 2019-07-31 Release date: 2020-11-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.35 Å) Cite: 2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin. Biochem.J., 477, 2020
4J1X	Crystal Structure of Fe(II)-HppE with alternative substrate (S)-1-HPP Descriptor: Epoxidase, FE (II) ION, GLYCEROL, ... Authors: Drennan, C.L, Dey, M. Deposit date: 2013-02-03 Release date: 2013-04-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reaction. Nature, 496, 2013
4J1W	Crystal Structure of Fe(II)-HppE with alternative substrate (R)-1-HPP Descriptor: Epoxidase, FE (II) ION, GLYCEROL, ... Authors: Drennan, C.L, Dey, M. Deposit date: 2013-02-03 Release date: 2013-04-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.72 Å) Cite: Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reaction. Nature, 496, 2013
4YV9	X-ray crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2 Descriptor: Cyclosporin A, SULFATE ION, Transcriptional regulator Authors: Neiditch, M.B, Parashar, V. Deposit date: 2015-03-19 Release date: 2015-04-08 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Rgg protein structure-function and inhibition by cyclic peptide compounds. Proc.Natl.Acad.Sci.USA, 112, 2015
4YG7	Structure of FL autorepression promoter complex Descriptor: Antitoxin HipB, DNA (50-MER), Serine/threonine-protein kinase HipA Authors: Schumacher, M.A. Deposit date: 2015-02-25 Release date: 2015-07-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.77 Å) Cite: HipBA-promoter structures reveal the basis of heritable multidrug tolerance. Nature, 524, 2015
4YV6	X-ray crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2 Descriptor: SULFATE ION, Transcriptional regulator Authors: Neiditch, M.B, Parashar, V. Deposit date: 2015-03-19 Release date: 2015-04-08 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (2.053 Å) Cite: Rgg protein structure-function and inhibition by cyclic peptide compounds. Proc.Natl.Acad.Sci.USA, 112, 2015
2GRM	Crystal structure of PrgX/iCF10 complex Descriptor: PrgX, peptide Authors: Shi, K, Kozlowicz, B.K, Gu, Z.Y, Ohlendorf, D.H, Earhart, C.A, Dunny, G.M. Deposit date: 2006-04-24 Release date: 2007-04-03 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3 Å) Cite: Molecular basis for control of conjugation by bacterial pheromone and inhibitor peptides. Mol.Microbiol., 62, 2006
2GRL	Crystal structure of dCT/iCF10 complex Descriptor: PrgX, peptide Authors: Shi, K, Kozlowicz, B.K, Gu, Z.Y, Ohlendorf, D.H, Earhart, C.A, Dunny, G.M. Deposit date: 2006-04-24 Release date: 2007-04-03 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3 Å) Cite: Molecular basis for control of conjugation by bacterial pheromone and inhibitor peptides. Mol.Microbiol., 62, 2006

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