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3ZVR
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BU of 3zvr by Molmil
Crystal structure of Dynamin
Descriptor: DYNAMIN-1, PENTAETHYLENE GLYCOL
Authors:Ford, M.G.J, Jenni, S, Nunnari, J.
Deposit date:2011-07-27
Release date:2011-09-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Crystal Structure of Dynamin
Nature, 477, 2011
3ZYS
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BU of 3zys by Molmil
Human dynamin 1 deltaPRD polymer stabilized with GMPPCP
Descriptor: DYNAMIN-1, INTERFERON-INDUCED GTP-BINDING PROTEIN MX1
Authors:Chappie, J.S, Mears, J.A, Fang, S, Leonard, M, Schmid, S.L, Milligan, R.A, Hinshaw, J.E, Dyda, F.
Deposit date:2011-08-24
Release date:2011-10-12
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (12.2 Å)
Cite:A Pseudoatomic Model of the Dynamin Polymer Identifies a Hydrolysis-Dependent Powerstroke.
Cell(Cambridge,Mass.), 147, 2011
4F7H
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BU of 4f7h by Molmil
The crystal structure of kindlin-2 pleckstrin homology domain in free form
Descriptor: Fermitin family homolog 2, S,R MESO-TARTARIC ACID
Authors:Liu, Y, Zhu, Y, Qin, J, Ye, S, Zhang, R.
Deposit date:2012-05-16
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation.
Protein Cell, 3, 2012
1DBH
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BU of 1dbh by Molmil
DBL AND PLECKSTRIN HOMOLOGY DOMAINS FROM HSOS1
Descriptor: PROTEIN (HUMAN SOS 1)
Authors:Soisson, S.M, Kuriyan, J.
Deposit date:1998-12-17
Release date:1998-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein.
Cell(Cambridge,Mass.), 95, 1998
4BBK
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BU of 4bbk by Molmil
Structural and functional characterisation of the kindlin-1 pleckstrin homology domain
Descriptor: FERMITIN FAMILY HOMOLOG 1, GLYCEROL
Authors:Yates, L.A, Lumb, C.N, Brahme, N.N, Zalyte, R, Bird, L.E, De Colibus, L, Owens, R.J, Calderwood, D.A, Sansom, M.S.P, Gilbert, R.J.C.
Deposit date:2012-09-25
Release date:2012-11-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Characterisation of the Kindlin-1 Pleckstrin Homology Domain
J.Biol.Chem., 287, 2012
4GMV
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BU of 4gmv by Molmil
Crystal Structure of the coiled-coil, RA and PH domains of Lamellipodin
Descriptor: Ras-associated and pleckstrin homology domains-containing protein 1
Authors:Chang, Y.C.E, Wu, J.
Deposit date:2012-08-16
Release date:2012-11-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling.
Protein Cell, 4, 2013
4GN1
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BU of 4gn1 by Molmil
Crystal Structure of the RA and PH domains of Lamellipodin
Descriptor: MALONATE ION, Ras-associated and pleckstrin homology domains-containing protein 1
Authors:Chang, Y.C.E, Wu, J.
Deposit date:2012-08-16
Release date:2012-11-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling.
Protein Cell, 4, 2013
4GZU
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BU of 4gzu by Molmil
Crystal structure of the DH-PH-PH domain of FARP2
Descriptor: FERM, RhoGEF and pleckstrin domain-containing protein 2
Authors:He, X, Zhang, X.
Deposit date:2012-09-06
Release date:2013-03-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2.
Structure, 21, 2013
4H6Y
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BU of 4h6y by Molmil
Crystal structure of the DH-PH-PH domain of FARP1
Descriptor: FERM, RhoGEF and pleckstrin domain-containing protein 1
Authors:He, X, Zhang, X.
Deposit date:2012-09-19
Release date:2013-03-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.09 Å)
Cite:Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2.
Structure, 21, 2013
4H8S
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BU of 4h8s by Molmil
Crystal structure of human APPL2BARPH domain
Descriptor: DCC-interacting protein 13-beta
Authors:Martin, J.L, King, G.J.
Deposit date:2012-09-23
Release date:2012-10-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Membrane Curvature Protein Exhibits Interdomain Flexibility and Binds a Small GTPase.
J.Biol.Chem., 287, 2012
4CKH
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BU of 4ckh by Molmil
Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy
Descriptor: ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1
Authors:Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F.
Deposit date:2014-01-06
Release date:2014-10-15
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (14 Å)
Cite:A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature.
Dev.Cell, 31, 2014
4CKG
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BU of 4ckg by Molmil
Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy
Descriptor: ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1
Authors:Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F.
Deposit date:2014-01-06
Release date:2014-10-15
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (12 Å)
Cite:A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature.
Dev.Cell, 31, 2014
4K2O
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BU of 4k2o by Molmil
The Structure of a Triple Mutant of the Tiam1 PH-CC-Ex Domain
Descriptor: T-lymphoma invasion and metastasis-inducing protein 1
Authors:Joshi, M, Gakhar, L, Fuentes, E.J.
Deposit date:2013-04-09
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:High-resolution structure of the Tiam1 PHn-CC-Ex domain.
Acta Crystallogr.,Sect.F, 69, 2013
4K2P
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BU of 4k2p by Molmil
The Structure of a Quintuple Mutant of the Tiam1 PH-CC-Ex Domain
Descriptor: CALCIUM ION, T-lymphoma invasion and metastasis-inducing protein 1
Authors:Joshi, M, Gakhar, L, Fuentes, E.J.
Deposit date:2013-04-09
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:High-resolution structure of the Tiam1 PHn-CC-Ex domain.
Acta Crystallogr.,Sect.F, 69, 2013
2Z0O
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BU of 2z0o by Molmil
Crystal structure of APPL1-BAR-PH domain
Descriptor: DCC-interacting protein 13-alpha
Authors:Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-07
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Crystal structure of APPL1-BAR-PH domain
To be Published
2Z0P
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BU of 2z0p by Molmil
Crystal structure of PH domain of Bruton's tyrosine kinase
Descriptor: (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, Tyrosine-protein kinase BTK, ZINC ION
Authors:Murayama, K, Kato-Murayama, M, Mishima, C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-07
Release date:2008-05-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Crystal structure of the Bruton's tyrosine kinase PH domain with phosphatidylinositol
Biochem.Biophys.Res.Commun., 377, 2008
2YS3
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BU of 2ys3 by Molmil
Solution structure of the PH domain of Kindlin-3 from human
Descriptor: Unc-112-related protein 2
Authors:Li, H, Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-03
Release date:2007-10-09
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of Kindlin-3 from human
To be Published
2Z0Q
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BU of 2z0q by Molmil
Crystal structure of DH-PH domain of RhoGEF3(Xpln)
Descriptor: Rho guanine nucleotide exchange factor 3, SULFATE ION
Authors:Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-07
Release date:2008-05-13
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structure of the Rho-specific guanine nucleotide-exchange factor Xpln
Acta Crystallogr.,Sect.F, 68, 2012
2LKO
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BU of 2lko by Molmil
Structural Basis of Phosphoinositide Binding to Kindlin-2 Pleckstrin Homology Domain in Regulating Integrin Activation
Descriptor: Fermitin family homolog 2, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE
Authors:Liu, J, Fukuda, K, Xu, Z.
Deposit date:2011-10-17
Release date:2011-10-26
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation.
J.Biol.Chem., 286, 2011
2LUL
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BU of 2lul by Molmil
Solution NMR Structure of PH Domain of Tyrosine-protein kinase Tec from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR3504C
Descriptor: Tyrosine-protein kinase Tec, ZINC ION
Authors:Liu, G, Xiao, R, Janjua, H, Hamilton, K, Shastry, R, Kohan, E, Acton, T.B, Everett, J.K, Lee, H, Pederson, K, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-06-15
Release date:2012-08-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution NMR Structure of PH Domain of Tyrosine-protein kinase Tec from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR3504C
To be Published
2Q13
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BU of 2q13 by Molmil
Crystal structure of BAR-PH domain of APPL1
Descriptor: DCC-interacting protein 13 alpha
Authors:Zhu, G, Zhang, X.C.
Deposit date:2007-05-23
Release date:2007-08-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5.
Embo J., 26, 2007
2R09
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BU of 2r09 by Molmil
Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor
Descriptor: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Cytohesin-3, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ...
Authors:DiNitto, J.P, Delprato, A, Gabe Lee, M.T, Cronin, T.C, Huang, S, Guilherme, A, Czech, M.P, Lambright, D.G.
Deposit date:2007-08-17
Release date:2007-12-04
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors.
Mol.Cell, 28, 2007
2R0D
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BU of 2r0d by Molmil
Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor
Descriptor: Cytohesin-3, DI(HYDROXYETHYL)ETHER, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ...
Authors:DiNitto, J.P, Delprato, A, Gabe Lee, M.T, Cronin, T.C, Huang, S, Guilherme, A, Czech, M.P, Lambright, D.G.
Deposit date:2007-08-18
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors.
Mol.Cell, 28, 2007
2ELB
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BU of 2elb by Molmil
Crystal Structure of the BAR-PH domain of human APPL1
Descriptor: Adapter protein containing PH domain, PTB domain and leucine zipper motif 1
Authors:Li, J, Mao, X, Dong, L.Q, Liu, F, Tong, L.
Deposit date:2007-03-27
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of the BAR-PH and PTB Domains of Human APPL1
Structure, 15, 2007
1XDV
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BU of 1xdv by Molmil
Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang.
Descriptor: Son of sevenless protein homolog 1
Authors:Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
Deposit date:2004-09-08
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004

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