Mine: Updated entries

6FFT
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NEUTRON STRUCTURE OF HUMAN TRANSTHYRETIN (TTR) S52P MUTANT IN COMPLEX WITH TAFAMIDIS AT ROOM TEMPERATURE TO 2A RESOLUTION (QUASI-LAUE)
Descriptor:Transthyretin, 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid
Authors:Yee, A.W., Moulin, M., Blakeley, M.P., Haertlein, M., Mitchell, E.P., Forsyth, V.T.
Deposit date:2018-01-09
Release date:2019-01-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2 Å), NEUTRON DIFFRACTION
Cite:A molecular mechanism for transthyretin amyloidogenesis.
Nat Commun, 10, 2019
6FNQ
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ERGOTHIONEINE-BIOSYNTHETIC METHYLTRANSFERASE EGTD IN COMPLEX WITH N,N,N-TRIMETHYLHISTIDINE (HERCYNINE)
Descriptor:Histidine N-alpha-methyltransferase, N,N,N-trimethyl-histidine, MAGNESIUM ION, ...
Authors:Vit, A., Blankenfeldt, W., Seebeck, F.P.
Deposit date:2018-02-05
Release date:2018-06-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol., 13, 2018
6G7G
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STRUCTURE OF SPH (SELF-INCOMPATIBILITY PROTEIN HOMOLOGUE) PROTEINS, A WIDESPREAD FAMILY OF SMALL, HIGHLY STABLE, SECRETED PROTEINS FROM PLANTS
Descriptor:S-protein homolog 15
Authors:Rajasekar, K.V., Coulthard, R.J., Ride, J.P., Ji, S., Winn, P.J., Wheeler, M.P., Hyde, E.I., Smith, L.J.
Deposit date:2018-04-06
Release date:2019-03-06
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:Structure of SPH (self-incompatibility protein homologue) proteins: a widespread family of small, highly stable, secreted proteins.
Biochem.J., 476, 2019
6GB5
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STRUCTURE OF H-2DB WITH TRUNCATED SEV PEPTIDE AND GL
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Hafstrand, I., Sandalova, T., Achour, A.
Deposit date:2018-04-13
Release date:2019-03-06
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin.
Proc.Natl.Acad.Sci.USA, 116, 2019
6GB6
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STRUCTURE OF H-2KB WITH DIPEPTIDE GL
Descriptor:H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, ...
Authors:Hafstrand, I., Sandalova, T., Achour, A.
Deposit date:2018-04-13
Release date:2019-03-06
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin.
Proc.Natl.Acad.Sci.USA, 116, 2019
6GB7
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STRUCTURE OF H-2DB WITH SCOOP LOOP FROM TAPASIN
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Hafstrand, I., Sandalova, T., Achour, A.
Deposit date:2018-04-13
Release date:2019-03-06
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin.
Proc.Natl.Acad.Sci.USA, 116, 2019
6GH0
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TWO-QUARTET KIT* G-QUADRUPLEX IS FORMED VIA DOUBLE-STRANDED PRE-FOLDED STRUCTURE
Descriptor:DNA (5'-D(*GP*GP*CP*GP*AP*GP*GP*AP*GP*GP*GP*GP*CP*GP*TP*GP*GP*CP*CP*GP*GP*C)-3')
Authors:Kotar, A., Rigo, R., Sissi, C., Plavec, J.
Deposit date:2018-05-04
Release date:2019-01-09
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:Two-quartet kit* G-quadruplex is formed via double-stranded pre-folded structure.
Nucleic Acids Res., 47, 2019
6GVJ
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HUMAN MPS1 KINASE DOMAIN WITH ORDERED ACTIVATION LOOP
Descriptor:Dual specificity protein kinase TTK, GLYCEROL, CHLORIDE ION
Authors:Roorda, J.C., Hiruma, Y., Joosten, R.P., Perrakis, A.
Deposit date:2018-06-21
Release date:2019-01-09
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:A crystal structure of the human protein kinase Mps1 reveals an ordered conformation of the activation loop.
Proteins, 87, 2019
6H2X
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MUKB COILED-COIL ELBOW FROM E. COLI
Descriptor:Chromosome partition protein MukB,Chromosome partition protein MukB
Authors:Buermann, F., Lowe, J.
Deposit date:2018-07-16
Release date:2019-03-06
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A folded conformation of MukBEF and cohesin.
Nat.Struct.Mol.Biol., 26, 2019
6HAG
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THE STRUCTURE OF THE SAM/SAH-BINDING RIBOSWITCH.
Descriptor:SAM Riboswitch, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Weickhmann, A.K.
Deposit date:2018-08-07
Release date:2019-01-09
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:The structure of the SAM/SAH-binding riboswitch.
Nucleic Acids Res., 47, 2019
6HEF
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ROOM TEMPERATURE STRUCTURE OF THE (SR)CA2+-ATPASE CA2-E1-CAAMPPCP FORM
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, CALCIUM ION, ...
Authors:Hjorth-Jensen, S., Sorensen, T.L.M., Oksanen, E., Andersen, J.L., Olesen, C., Moller, J.V., Nissen, P.
Deposit date:2018-08-20
Release date:2018-08-29
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (3.538 Å)
Cite:Membrane-protein crystals for neutron diffraction.
Acta Crystallogr D Struct Biol, 74, 2018
6HR7
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HMG-COA REDUCTASE FROM METHANOTHERMOCOCCUS THERMOLITHOTROPHICUS APO FORM AT 2.4 A RESOLUTION
Descriptor:HMG-CoA reductase, SULFATE ION, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ...
Authors:Wagner, T., Voegeli, B., Erb, T.J., Shima, S.
Deposit date:2018-09-26
Release date:2019-02-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of archaeal HMG-CoA reductase: insights into structural changes of the C-terminal helix of the class-I enzyme.
Febs Lett., 593, 2019
6HR8
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HMG-COA REDUCTASE FROM METHANOTHERMOCOCCUS THERMOLITHOTROPHICUS IN COMPLEX WITH NADPH AT 2.9 A RESOLUTION
Descriptor:HMG-CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ...
Authors:Wagner, T., Voegeli, B., Erb, T.J., Shima, S.
Deposit date:2018-09-26
Release date:2019-02-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of archaeal HMG-CoA reductase: insights into structural changes of the C-terminal helix of the class-I enzyme.
Febs Lett., 593, 2019
6HV2
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MMP-13 IN COMPLEX WITH THE PEPTIDE IMISF
Descriptor:Collagenase 3, ZINC ION, CALCIUM ION, ...
Authors:Mittl, P., Riedl, R., Hohl, D.
Deposit date:2018-10-10
Release date:2019-01-30
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.709 Å)
Cite:Drug Design Inspired by Nature: Crystallographic Detection of an Auto-Tailored Protease Inhibitor Template.
Angew.Chem.Int.Ed.Engl., 58, 2019
6HY2
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STRUCTURE GUIDED DESIGN OF AN ANTIBACTERIAL PEPTIDE THAT TARGETS UDP-N-ACETYLGLUCOSAMINE ACYLTRANSFERASE
Descriptor:Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, TRP-MET-LEU-ASP-PRO-ILE-ALA-GLY-LYS-TRP-SER-ARG
Authors:Williams, A.H., Dangkulwanich, M.
Deposit date:2018-10-19
Release date:2019-01-23
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase.
Sci Rep, 9, 2019
6HY3
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THREE-DIMENSIONAL STRUCTURE OF AGAC FROM ZOBELLIA GALACTANIVORANS
Descriptor:Beta-agarase C, MAGNESIUM ION, GLYCEROL, ...
Authors:Naretto, A., Fanuel, M., Ropartz, D., Rogniaux, H., Larocque, R., Czjzek, M., Tellier, C., Michel, G.
Deposit date:2018-10-19
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The agar-specific hydrolaseZgAgaC from the marine bacteriumZobellia galactanivoransdefines a new GH16 protein subfamily.
J.Biol.Chem., 2019
6HZ2
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SOLUTION NMR STRUCTURE OF MAXIMIN 3 IN 50% TRIFLUOROETHANOL
Descriptor:Maximins 3/H11 type 2
Authors:Benetti, S., Timmons, P.B., Hewage, C.M.
Deposit date:2018-10-22
Release date:2019-02-20
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:NMR model structure of the antimicrobial peptide maximin 3.
Eur.Biophys.J., 48, 2019
6I0Z
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CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH COMPOUND 1
Descriptor:Fascin, ~{N}-(2,4-dichlorophenyl)-~{N}-methyl-ethanamide
Authors:Schuettelkopf, A.W.
Deposit date:2018-10-27
Release date:2019-02-27
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Bioorg.Med.Chem.Lett., 29, 2019
6I10
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CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH COMPOUND 2
Descriptor:Fascin, 1-[(3~{R})-1,1-bis(oxidanylidene)thiolan-3-yl]-5-[(3,4-dichlorophenyl)methyl]pyrazolo[3,4-d]pyrimidin-4-one, ACETATE ION, ...
Authors:Schuettelkopf, A.W.
Deposit date:2018-10-27
Release date:2019-02-27
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Bioorg.Med.Chem.Lett., 29, 2019
6I11
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CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH COMPOUND 3
Descriptor:Fascin, ACETATE ION, ~{N}-(1-methylpyrazol-4-yl)-1-oxidanylidene-2-(phenylmethyl)isoquinoline-4-carboxamide
Authors:Schuettelkopf, A.W.
Deposit date:2018-10-27
Release date:2019-02-27
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Bioorg.Med.Chem.Lett., 29, 2019
6I12
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CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH COMPOUND 5
Descriptor:Fascin, ACETATE ION, 2-[(4-chlorophenyl)methyl]-~{N}-(1-methylpyrazol-4-yl)-1-oxidanylidene-isoquinoline-4-carboxamide
Authors:Schuettelkopf, A.W.
Deposit date:2018-10-27
Release date:2019-02-27
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Bioorg.Med.Chem.Lett., 29, 2019
6I13
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CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH COMPOUND 7
Descriptor:Fascin, ACETATE ION, 1,2-ETHANEDIOL, ...
Authors:Schuettelkopf, A.W.
Deposit date:2018-10-27
Release date:2019-02-27
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Bioorg.Med.Chem.Lett., 29, 2019
6I14
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CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH COMPOUND 9
Descriptor:Fascin, ACETATE ION, 2-[(3,4-dichlorophenyl)methyl]-~{N}-(1-methylpyrazol-4-yl)-1-oxidanylidene-isoquinoline-4-carboxamide
Authors:Schuettelkopf, A.W.
Deposit date:2018-10-27
Release date:2019-02-27
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Bioorg.Med.Chem.Lett., 29, 2019
6I15
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CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH COMPOUND 11
Descriptor:Fascin, 1,2-ETHANEDIOL, ACETATE ION, ...
Authors:Schuettelkopf, A.W.
Deposit date:2018-10-27
Release date:2019-02-27
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Bioorg.Med.Chem.Lett., 29, 2019
6I16
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CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH COMPOUND 15
Descriptor:Fascin, ACETATE ION, 6-[(3,4-dichlorophenyl)methyl]-~{N}-(1-methylpyrazol-4-yl)-5-oxidanylidene-1,6-naphthyridine-8-carboxamide
Authors:Schuettelkopf, A.W.
Deposit date:2018-10-27
Release date:2019-02-27
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Bioorg.Med.Chem.Lett., 29, 2019