PDB: 339 resultsInfo pagesStatus searchChemie searchBIRD

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3E4C	Procaspase-1 zymogen domain crystal structure Descriptor: Caspase-1, MAGNESIUM ION Authors: Elliott, J.M, Rouge, L, Wiesmann, C, Scheer, J.M. Deposit date: 2008-08-11 Release date: 2008-12-30 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Crystal structure of procaspase-1 zymogen domain reveals insight into inflammatory caspase autoactivation J.Biol.Chem., 284, 2009
4DCO	Crystal Structure of caspase 3, L168Y mutant Descriptor: Caspase Inhibitor AC-DEVD-CHO, Caspase-3 subunit p12, Caspase-3 subunit p17 Authors: Chung, S.J, Kang, H.J, Kim, S.J. Deposit date: 2012-01-18 Release date: 2012-12-12 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7 Biosci.Rep., 32, 2012
4JR2	Human procaspase-7/caspase-7 heterodimer bound to Ac-DEVD-CMK Descriptor: Ac-DEVD-CMK, CHLORIDE ION, Procaspase-7 Authors: Thomsen, N.D, Wells, J.A. Deposit date: 2013-03-20 Release date: 2013-05-08 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation. Proc.Natl.Acad.Sci.USA, 110, 2013
3EDQ	Crystal structure of Caspase-3 with inhibitor AC-LDESD-CHO Descriptor: AC-LDESD-CHO peptide, Caspase-3 Authors: Fu, G. Deposit date: 2008-09-03 Release date: 2008-10-28 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Structural basis for executioner caspase recognition of P5 position in substrates. Apoptosis, 13, 2008
4DCJ	Crystal structure of caspase 3, L168D mutant Descriptor: Caspase Inhibitor AC-DEVD-CHO, Caspase-3 subunit p12, Caspase-3 subunit p17 Authors: Chung, S.J, Kang, H.J, Kim, S.J. Deposit date: 2012-01-17 Release date: 2012-12-12 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7 Biosci.Rep., 32, 2012
4JQY	Human procaspase-3, crystal form 1 Descriptor: Procaspase-3 Authors: Thomsen, N.D, Wells, J.A. Deposit date: 2013-03-20 Release date: 2013-05-08 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.495 Å) Cite: Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation. Proc.Natl.Acad.Sci.USA, 110, 2013
4JR1	Human procaspase-7 bound to Ac-DEVD-CMK Descriptor: Ac-DEVD-CMK, CHLORIDE ION, Procaspase-7 Authors: Thomsen, N.D, Wells, J.A. Deposit date: 2013-03-20 Release date: 2013-05-08 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.149 Å) Cite: Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation. Proc.Natl.Acad.Sci.USA, 110, 2013
4EHA	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.696 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4JJE	Caspase-3 specific unnatural amino acid peptides Descriptor: Caspase inhibitor, Caspase-3 Authors: Vickers, C.J, Gonzalez-Paez, G.E, Wolan, D.W. Deposit date: 2013-03-07 Release date: 2013-06-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.481 Å) Cite: Selective Detection of Caspase-3 versus Caspase-7 Using Activity-Based Probes with Key Unnatural Amino Acids. Acs Chem.Biol., 8, 2013
4JQZ	Human procaspase-3, crystal form 2 Descriptor: Procaspase-3 Authors: Thomsen, N.D, Wells, J.A. Deposit date: 2013-03-20 Release date: 2013-05-08 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.889 Å) Cite: Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation. Proc.Natl.Acad.Sci.USA, 110, 2013
4JJ7	Caspase-3 specific unnatural amino acid-based peptides Descriptor: Caspase inhibitor, Caspase-8, DITHIANE DIOL Authors: Vickers, C.J, Gonzalez-Paez, G.E, Wolan, D.W. Deposit date: 2013-03-07 Release date: 2013-06-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.178 Å) Cite: Selective Detection of Caspase-3 versus Caspase-7 Using Activity-Based Probes with Key Unnatural Amino Acids. Acs Chem.Biol., 8, 2013
4EHH	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4JB8	Caspase-7 in Complex with DARPin C7_16 Descriptor: Caspase-7 subunit p11, Caspase-7 subunit p20, DARPin C7_16 Authors: Fluetsch, A, Seeger, M.A, Gruetter, M.G. Deposit date: 2013-02-19 Release date: 2013-08-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity. Protein Sci., 22, 2013
4JR0	Human procaspase-3 bound to Ac-DEVD-CMK Descriptor: Ac-DEVD-CMK, CHLORIDE ION, Procaspase-3 Authors: Thomsen, N.D, Wells, J.A. Deposit date: 2013-03-20 Release date: 2013-05-08 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.796 Å) Cite: Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation. Proc.Natl.Acad.Sci.USA, 110, 2013
4JJ8	Caspase-3 specific unnatural amino acid peptides Descriptor: Caspase Inhibitor, Caspase-7 Authors: Vickers, C.J, Gonzalez-Paez, G.E, Wolan, D.W. Deposit date: 2013-03-07 Release date: 2013-06-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.937 Å) Cite: Selective Detection of Caspase-3 versus Caspase-7 Using Activity-Based Probes with Key Unnatural Amino Acids. Acs Chem.Biol., 8, 2013
4EHL	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.799 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4EHD	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.581 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4EHF	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.655 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4EJF	Allosteric peptides that bind to a caspase zymogen and mediate caspase tetramerization Descriptor: Caspase-6, PHOSPHATE ION, phage-derived peptide 419 Authors: Murray, J.M. Deposit date: 2012-04-06 Release date: 2012-06-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.6465 Å) Cite: Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization. Nat.Chem.Biol., 8, 2012
4EHN	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4EHK	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.668 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4F6P	Crystal structure of the yeast metacaspase Yca1 C276A mutant Descriptor: 1,1-diphenylethanol, Metacaspase-1 Authors: Wong, A.H, Yan, C.Y, Shi, Y.G. Deposit date: 2012-05-15 Release date: 2013-03-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.619 Å) Cite: Crystal structure of the metacaspase Yca1 To be Published
4FDL	Crystal structure of Caspase-7 Descriptor: Caspase-7 Authors: Kabaleeswaran, V. Deposit date: 2012-05-28 Release date: 2012-08-01 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.801 Å) Cite: A class of allosteric caspase inhibitors identified by high-throughput screening. Mol.Cell, 47, 2012
4FEA	Crystal structure of CASPASE-7 in Complex with allosteric inhibitor Descriptor: Caspase-7, chloro{methyl hydrogenato(3-)-kappa~2~N,S [pyridin-2-yl(pyridin-2(1H)-ylidene-kappaN)methyl]carbonodithiohydrazonate}copper Authors: Kabaleeswaran, V. Deposit date: 2012-05-29 Release date: 2012-08-01 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.79 Å) Cite: A class of allosteric caspase inhibitors identified by high-throughput screening. Mol.Cell, 47, 2012
4F6O	Crystal structure of the yeast metacaspase Yca1 Descriptor: 1,1-diphenylethanol, Metacaspase-1 Authors: Wong, A.H, Yan, C.Y, Shi, Y.G. Deposit date: 2012-05-15 Release date: 2012-07-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.681 Å) Cite: Crystal structure of the yeast metacaspase Yca1. J.Biol.Chem., 287, 2012

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