4TWK
| Crystal structure of human two pore domain potassium ion channel TREK1 (K2P2.1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Octyl Glucose Neopentyl Glycol, ... | Authors: | Pike, A.C.W, Dong, Y.Y, Tessitore, A, Goubin, S, Strain-Damerell, C, Mukhopadhyay, S, Kupinska, K, Wang, D, Chalk, R, Berridge, G, Grieben, M, Shrestha, L, Ang, J.H, Mackenzie, A, Quigley, A, Bushell, S.R, Shintre, C.A, Faust, B, Chu, A, Dong, L, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Carpenter, E.P. | Deposit date: | 2014-06-30 | Release date: | 2014-08-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of human two pore domain potassium ion channel TREK1 (K2P2.1) To Be Published
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3GB7
| Potassium Channel KcsA-Fab complex in Li+ | Descriptor: | DIACYL GLYCEROL, NICKEL (II) ION, Voltage-gated potassium channel, ... | Authors: | Thompson, A.N, Ilsoo, K, Panosian, T.D, Iverson, T.M, Allen, T.W, Nimigean, C.M. | Deposit date: | 2009-02-18 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Mechanism of potassium-channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore. Nat.Struct.Mol.Biol., 16, 2009
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3HPL
| KcsA E71H-F103A mutant in the closed state | Descriptor: | Antibody Fab heavy chain, Antibody fab light chain, POTASSIUM ION, ... | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | Deposit date: | 2009-06-04 | Release date: | 2010-06-23 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for the coupling between activation and inactivation gates in K(+) channels. Nature, 466, 2010
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2HFE
| Rb+ complex of a K channel with an amide to ester substitution in the selectivity filter | Descriptor: | (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, FAB Heavy Chain, FAB Light Chain, ... | Authors: | Valiyaveetil, F.I, MacKinnon, R, Muir, T.W. | Deposit date: | 2006-06-23 | Release date: | 2006-09-12 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. J.Am.Chem.Soc., 128, 2006
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3IGA
| Potassium Channel KcsA-Fab complex in Li+ and K+ | Descriptor: | Antibody Fab Fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | Authors: | Thompson, A.N, Ilsoo, K, Panosian, T.D, Iverson, T.M, Allen, T.W, Nimigean, C.M. | Deposit date: | 2009-07-27 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Mechanism of potassium-channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore. Nat.Struct.Mol.Biol., 16, 2009
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2HJF
| Potassium channel kcsa-fab complex with tetrabutylammonium (TBA) | Descriptor: | Antibody fragment Heavy chain, Antibody fragment Light chain, POTASSIUM ION, ... | Authors: | Faraldo-Gomez, J.D, Kutluay, E, Jogini, V, Zhao, Y, Heginbotham, L, Roux, B. | Deposit date: | 2006-06-30 | Release date: | 2006-12-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanism of Intracellular Block of the KcsA K(+) Channel by Tetrabutylammonium: Insights from X-ray Crystallography, Electrophysiology and Replica-exchange Molecular Dynamics Simulations. J.Mol.Biol., 365, 2007
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2HVJ
| Crystal structure of KcsA-Fab-TBA complex in low K+ | Descriptor: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, NONAN-1-OL, POTASSIUM ION, ... | Authors: | Zhou, Y. | Deposit date: | 2006-07-28 | Release date: | 2007-02-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel. J.Mol.Biol., 366, 2007
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2HVK
| crystal structure of the KcsA-Fab-TBA complex in high K+ | Descriptor: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, Antibody Fab heavy chain, Antibody Fab light chain, ... | Authors: | Zhou, Y. | Deposit date: | 2006-07-28 | Release date: | 2007-02-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel. J.Mol.Biol., 366, 2007
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3IFX
| Crystal structure of the Spin-labeled KcsA mutant V48R1 | Descriptor: | POTASSIUM ION, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, TETRABUTYLAMMONIUM ION, ... | Authors: | Cieslak, J.A, Focia, P.J, Gross, A. | Deposit date: | 2009-07-26 | Release date: | 2010-02-09 | Last modified: | 2023-09-06 | Method: | EPR (3.56 Å), X-RAY DIFFRACTION | Cite: | Electron Spin-Echo Envelope Modulation (ESEEM) Reveals Water and Phosphate Interactions with the KcsA Potassium Channel Biochemistry, 49, 2010
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2IH3
| Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation | Descriptor: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB Heavy Chain, FAB Light Chain, ... | Authors: | Valiyaveetil, F.I, Leonetti, M, Muir, T.W, MacKinnon, R. | Deposit date: | 2006-09-25 | Release date: | 2006-11-21 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation. Science, 314, 2006
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2ITD
| Potassium Channel KcsA-Fab complex in Barium Chloride | Descriptor: | BARIUM ION, Voltage-gated potassium channel, antibody Fab fragment heavy chain, ... | Authors: | Lockless, S.W, Zhou, M, MacKinnon, R. | Deposit date: | 2006-10-19 | Release date: | 2007-05-15 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Plos Biol., 5, 2007
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3K03
| Crystal Structure of CNG mimicking NaK mutant, NaK-DTPP, K+ complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein NaK | Authors: | Jiang, Y, Derebe, M.G. | Deposit date: | 2009-09-24 | Release date: | 2011-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites. Proc.Natl.Acad.Sci.USA, 108, 2011
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2ITC
| Potassium Channel KcsA-Fab complex in Sodium Chloride | Descriptor: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, SODIUM ION, ... | Authors: | Lockless, S.W, Zhou, M, MacKinnon, R. | Deposit date: | 2006-10-19 | Release date: | 2007-05-15 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Plos Biol., 5, 2007
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3K04
| Crystal Structure of CNG mimicking NaK mutant, NaK-DTPP, Na+ complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Potassium channel protein NaK, SODIUM ION | Authors: | Jiang, Y, Derebe, M.G. | Deposit date: | 2009-09-24 | Release date: | 2011-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore. Proc.Natl.Acad.Sci.USA, 108, 2011
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2IH1
| Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation | Descriptor: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB Heavy Chain, FAB Light Chain, ... | Authors: | Valiyaveetil, F.I, Leonetti, M, Muir, T.W, MacKinnon, R. | Deposit date: | 2006-09-25 | Release date: | 2006-11-21 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation. Science, 314, 2006
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3K0D
| Crystal Structure of CNG mimicking NaK mutant, NaK-ETPP, K+ complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein NaK | Authors: | Jiang, Y, Derebe, M.G. | Deposit date: | 2009-09-24 | Release date: | 2011-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore. Proc.Natl.Acad.Sci.USA, 108, 2011
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3K08
| Crystal Structure of CNG mimicking NaK mutant, NaK-NTPP, Na+ complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Potassium channel protein NaK, SODIUM ION | Authors: | Jiang, Y, Derebe, M.G. | Deposit date: | 2009-09-24 | Release date: | 2011-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore. Proc.Natl.Acad.Sci.USA, 108, 2011
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3K06
| Crystal Structure of CNG mimicking NaK mutant, NaK-NTPP, K+ complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein NaK | Authors: | Jiang, Y, Derebe, M.G. | Deposit date: | 2009-09-24 | Release date: | 2011-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore. Proc.Natl.Acad.Sci.USA, 108, 2011
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3K0G
| Crystal Structure of CNG mimicking NaK mutant, NaK-ETPP, Na+ complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Potassium channel protein NaK, SODIUM ION | Authors: | Jiang, Y, Derebe, M.G. | Deposit date: | 2009-09-24 | Release date: | 2011-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore. Proc.Natl.Acad.Sci.USA, 108, 2011
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2JK5
| Potassium Channel KcsA in complex with Tetrabutylammonium in high K | Descriptor: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, ... | Authors: | Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A. | Deposit date: | 2008-08-15 | Release date: | 2009-11-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site. Biochemistry, 53, 2014
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3LDC
| High resolution open MthK pore structure crystallized in 100 mM K+ | Descriptor: | Calcium-gated potassium channel mthK, POTASSIUM ION | Authors: | Ye, S. | Deposit date: | 2010-01-12 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Novel insights into K(+) selectivity from high-resolution structures of an open K(+) channel pore. Nat.Struct.Mol.Biol., 17, 2010
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5CBH
| Structural and Functional Characterization of a Calcium-activated Cation channel from Tsukamurella Paurometabola | Descriptor: | CALCIUM ION, Ion transport 2 domain protein | Authors: | Dhakshnamoorthy, B, Rohaim, A, Rui, H, Blachowicz, L, Roux, B. | Deposit date: | 2015-06-30 | Release date: | 2016-07-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.37 Å) | Cite: | Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola. Nat Commun, 7, 2016
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2W0F
| Potassium Channel KcsA-Fab Complex with Tetraoctylammonium | Descriptor: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... | Authors: | Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A. | Deposit date: | 2008-08-14 | Release date: | 2009-11-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site. Biochemistry, 53, 2014
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5CBF
| Structural and Functional Characterization of a Calcium-activated Cation channel from Tsukamurella Paurometabola | Descriptor: | CALCIUM ION, Ion transport 2 domain protein | Authors: | Dhakshnamoorthy, B, Rohaim, A, Rui, H, Blachowicz, L, Roux, B. | Deposit date: | 2015-06-30 | Release date: | 2016-07-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.61 Å) | Cite: | Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola. Nat Commun, 7, 2016
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3T2M
| Crystal Structure of NaK Channel N68D Mutant | Descriptor: | POTASSIUM ION, Potassium channel protein | Authors: | Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. | Deposit date: | 2011-07-22 | Release date: | 2011-10-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.953 Å) | Cite: | Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation. Proc.Natl.Acad.Sci.USA, 108, 2011
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