2GWO
 
 | | crystal structure of TMDP | | Descriptor: | Dual specificity protein phosphatase 13 | | Authors: | Kim, S.J, Ryu, S.E, Kim, J.H. | | Deposit date: | 2006-05-05 | | Release date: | 2007-03-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of human TMDP, a testis-specific dual specificity protein phosphatase: implications for substrate specificity
Proteins, 66, 2007
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2G6Z
 | | Crystal structure of human DUSP5 | | Descriptor: | Dual specificity protein phosphatase 5, SULFATE ION | | Authors: | Kim, S.J, Ryu, S.E. | | Deposit date: | 2006-02-26 | | Release date: | 2007-01-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of the catalytic domain of human DUSP5, a dual specificity MAP kinase protein phosphatase
Proteins, 66, 2007
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2IMG
 | | Crystal structure of dual specificity protein phosphatase 23 from Homo sapiens in complex with ligand malate ion | | Descriptor: | D-MALATE, Dual specificity protein phosphatase 23 | | Authors: | Agarwal, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2006-10-04 | | Release date: | 2006-10-17 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Structure of human dual specificity protein phosphatase 23, VHZ, enzyme-substrate/product complex.
J.Biol.Chem., 283, 2008
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2HXP
 | | Crystal Structure of the human phosphatase (DUSP9) | | Descriptor: | Dual specificity protein phosphatase 9, PHOSPHATE ION | | Authors: | Madegowda, M, Eswaramoorthy, S, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2006-08-03 | | Release date: | 2006-08-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
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2HCM
 | | Crystal structure of mouse putative dual specificity phosphatase complexed with zinc tungstate, New York Structural Genomics Consortium | | Descriptor: | Dual specificity protein phosphatase, GLYCEROL, SODIUM ION, ... | | Authors: | Patskovsky, Y, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2006-06-17 | | Release date: | 2006-08-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
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1ZZW
 | | Crystal Structure of catalytic domain of Human MAP Kinase Phosphatase 5 | | Descriptor: | 1,2-ETHANEDIOL, Dual specificity protein phosphatase 10, SULFATE ION | | Authors: | Jeong, D.G, Yoon, T.S, Kim, J.H, Shim, M.Y, Jeong, S.K, Son, J.H, Ryu, S.E, Kim, S.J. | | Deposit date: | 2005-06-14 | | Release date: | 2006-07-04 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structure of the Catalytic Domain of Human MAP Kinase Phosphatase 5: Structural Insight into Constitutively Active Phosphatase.
J.Mol.Biol., 360, 2006
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2ESB
 | | Crystal structure of human DUSP18 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, Dual specificity protein phosphatase 18 | | Authors: | Kim, S.J, Ryu, S.E, Jeong, D.G, Cho, Y.H, Yoon, T.S, Kim, J.H. | | Deposit date: | 2005-10-25 | | Release date: | 2006-06-06 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of human DSP18, a member of the dual-specificity protein tyrosine phosphatase family.
Acta Crystallogr.,Sect.D, 62, 2006
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2C46
 | | CRYSTAL STRUCTURE OF THE HUMAN RNA guanylyltransferase and 5'- phosphatase | | Descriptor: | MRNA CAPPING ENZYME | | Authors: | Debreczeni, J, Johansson, C, Longman, E, Gileadi, O, SavitskySmee, P, Smee, C, Bunkoczi, G, Ugochukwu, E, von Delft, F, Sundstrom, M, Weigelt, J, Arrowsmith, C, Edwards, A, Knapp, S. | | Deposit date: | 2005-10-15 | | Release date: | 2005-11-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structure of the Human RNA Guanylyltransferase and 5'-Phosphatase
To be Published
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1YZ4
 | | Crystal structure of DUSP15 | | Descriptor: | SULFATE ION, dual specificity phosphatase-like 15 isoform a, octyl beta-D-glucopyranoside | | Authors: | Kim, S.J, Ryu, S.E, Jeong, D.G, Yoon, T.S, Kim, J.H, Cho, Y.H, Jeong, S.K, Lee, J.W, Son, J.H. | | Deposit date: | 2005-02-28 | | Release date: | 2005-11-01 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the catalytic domain of human VHY, a dual-specificity protein phosphatase
Proteins, 61, 2005
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1WRM
 | | Crystal structure of JSP-1 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, dual specificity phosphatase 22 | | Authors: | Yokota, T, Kashima, A, Kato, R, Sugio, S. | | Deposit date: | 2004-10-22 | | Release date: | 2005-10-22 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of human dual specificity phosphatase, JNK stimulatory phosphatase-1, at 1.5 A resolution
Proteins, 66, 2006
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1X24
 | | Prl-1 (ptp4a) | | Descriptor: | protein tyrosine phosphatase 4a1 | | Authors: | Zhang, Z.Y, Sun, J.P, Liu, S, Wang, W.Q, Yang, H. | | Deposit date: | 2005-04-20 | | Release date: | 2005-10-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion(,)
Biochemistry, 44, 2005
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1ZCK
 | | native structure prl-1 (ptp4a1) | | Descriptor: | ACETIC ACID, protein tyrosine phosphatase 4a1 | | Authors: | Sun, J.P, Wang, W.Q, Yang, H, Liu, S, Liang, F, Fedorov, A.A, Almo, S.C, Zhang, Z.Y. | | Deposit date: | 2005-04-12 | | Release date: | 2005-09-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion.
Biochemistry, 44, 2005
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1ZCL
 | | prl-1 c104s mutant in complex with sulfate | | Descriptor: | SULFATE ION, protein tyrosine phosphatase 4a1 | | Authors: | Sun, J.P, Wang, W.Q, Yang, H, Liu, S, Liang, F, Fedorov, A.A, Almo, S.C, Zhang, Z.Y. | | Deposit date: | 2005-04-12 | | Release date: | 2005-09-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion.
Biochemistry, 44, 2005
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1YN9
 | | Crystal structure of baculovirus RNA 5'-phosphatase complexed with phosphate | | Descriptor: | PHOSPHATE ION, polynucleotide 5'-phosphatase | | Authors: | Changela, A, Martins, A, Shuman, S, Mondragon, A. | | Deposit date: | 2005-01-24 | | Release date: | 2005-02-22 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of baculovirus RNA triphosphatase complexed with phosphate
J.Biol.Chem., 280, 2005
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1XM2
 | | Crystal structure of Human PRL-1 | | Descriptor: | SULFATE ION, Tyrosine Phosphatase | | Authors: | Jeong, D.G, Kim, S.J, Kim, J.H, Son, J.H, Ryu, S.E. | | Deposit date: | 2004-10-01 | | Release date: | 2005-01-25 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Trimeric structure of PRL-1 phosphatase reveals an active enzyme conformation and regulation mechanisms
J.Mol.Biol., 345, 2005
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1RXD
 | | Crystal structure of human protein tyrosine phosphatase 4A1 | | Descriptor: | protein tyrosine phosphatase type IVA, member 1; Protein tyrosine phosphatase IVA1 | | Authors: | Sun, J.P, Fedorov, A.A, Almo, S.C, Zhang, Z.Y, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2003-12-18 | | Release date: | 2004-12-28 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
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1OHE
 | | Structure of cdc14b phosphatase with a peptide ligand | | Descriptor: | CDC14B2 PHOSPHATASE, PEPTIDE LIGAND | | Authors: | Gray, C.H, Good, V.M, Tonks, N.K, Barford, D. | | Deposit date: | 2003-05-24 | | Release date: | 2003-07-24 | | Last modified: | 2019-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase
Embo J., 22, 2003
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1OHD
 | | structure of cdc14 in complex with tungstate | | Descriptor: | CDC14B2 PHOSPHATASE, TUNGSTATE(VI)ION | | Authors: | Gray, C.H, Good, V.M, Tonks, N.K, Barford, D. | | Deposit date: | 2003-05-24 | | Release date: | 2003-07-24 | | Last modified: | 2019-05-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase
Embo J., 22, 2003
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1OHC
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1M3G
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1J4X
 | | HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE C124S MUTANT-PEPTIDE COMPLEX | | Descriptor: | DDE(AHP)(TPO)G(PTR)VATR, DUAL SPECIFICITY PROTEIN PHOSPHATASE 3 | | Authors: | Schumacher, M.A, Todd, J.L, Tanner, K.G, Denu, J.M. | | Deposit date: | 2001-12-13 | | Release date: | 2001-12-19 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase.
Biochemistry, 41, 2002
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1I9T
 | | CRYSTAL STRUCTURE OF THE OXIDIZED RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME | | Descriptor: | CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ... | | Authors: | Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A. | | Deposit date: | 2001-03-20 | | Release date: | 2001-05-23 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
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1I9S
 | | CRYSTAL STRUCTURE OF THE RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME | | Descriptor: | CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ... | | Authors: | Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A. | | Deposit date: | 2001-03-20 | | Release date: | 2001-05-23 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
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1MKP
 | | CRYSTAL STRUCTURE OF PYST1 (MKP3) | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, PYST1 | | Authors: | Stewart, A.E, Dowd, S, Keyse, S, Mcdonald, N.Q. | | Deposit date: | 1998-07-11 | | Release date: | 1999-07-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation.
Nat.Struct.Biol., 6, 1999
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1VHR
 | | HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE VHR, SULFATE ION | | Authors: | Yuvaniyama, J, Denu, J.M, Dixon, J.E, Saper, M.A. | | Deposit date: | 1996-02-20 | | Release date: | 1996-06-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of the dual specificity protein phosphatase VHR.
Science, 272, 1996
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