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6H9S
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BU of 6h9s by Molmil
Crystal dimeric structure of Petrotoga mobilis lactate dehydrogenase with NADH
Descriptor: L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Roche, J, Engilberge, S, Girard, E, Madern, D.
Deposit date:2018-08-06
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Petrotoga mobilis lactate dehydrogenase at 1.9 Angstrom resolution
To Be Published
1EMD
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BU of 1emd by Molmil
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF ESCHERICHIA COLI MALATE DEHYDROGENASE, CITRATE AND NAD AT 1.9 ANGSTROMS RESOLUTION
Descriptor: CITRIC ACID, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Hall, M.D, Banaszak, L.J.
Deposit date:1993-03-25
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a ternary complex of Escherichia coli malate dehydrogenase citrate and NAD at 1.9 A resolution.
J.Mol.Biol., 232, 1993
6QSS
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BU of 6qss by Molmil
Crystal Structure of Ignicoccus islandicus malate dehydrogenase co-crystallized with 10 mM Tb-Xo4
Descriptor: CHLORIDE ION, Malate dehydrogenase, TERBIUM(III) ION, ...
Authors:Roche, J, Girard, E, Madern, D.
Deposit date:2019-02-21
Release date:2019-07-17
Last modified:2024-01-24
Method:SOLUTION SCATTERING (1.892 Å), X-RAY DIFFRACTION
Cite:The archaeal LDH-like malate dehydrogenase from Ignicoccus islandicus displays dual substrate recognition, hidden allostery and a non-canonical tetrameric oligomeric organization.
J.Struct.Biol., 208, 2019
6R8G
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BU of 6r8g by Molmil
Crystal structure of malate dehydrogenase from Plasmodium Falciparum in complex with 4-(3,4-difluorophenyl)thiazol-2-amine
Descriptor: 4-[3,4-bis(fluoranyl)phenyl]-1,3-thiazol-2-amine, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Romero, A.R, Calderone, V, Gentili, M, Lunev, S, Groves, M, Popowicz, G, Domling, A, Sattler, M.
Deposit date:2019-04-01
Release date:2020-04-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Fragment-Based Approach Identifies an Allosteric Pocket that Impacts Malate Dehydrogenase Activity
Commun Biol, 2021
1EZ4
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BU of 1ez4 by Molmil
CRYSTAL STRUCTURE OF NON-ALLOSTERIC L-LACTATE DEHYDROGENASE FROM LACTOBACILLUS PENTOSUS AT 2.3 ANGSTROM RESOLUTION
Descriptor: LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Uchikoba, H, Fushinobu, S, Wakagi, T, Konno, M, Taguchi, H, Matsuzawa, H.
Deposit date:2000-05-10
Release date:2001-12-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of non-allosteric L-lactate dehydrogenase from Lactobacillus pentosus at 2.3 A resolution: specific interactions at subunit interfaces.
Proteins, 46, 2002
6MV8
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LDHA structure in complex with inhibitor 14
Descriptor: (6S)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(2-hydroxyphenyl)-6-phenyl-5,6-dihydro-2H-pyran-2-one, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Eigenbrot, C.E, Ultsch, M, Wei, B.
Deposit date:2018-10-24
Release date:2019-10-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure-based Optimization of Potent, Cell-Active Hydroxylactam Inhibitors of Lactate Dehydrogenase
To Be Published
6ITL
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BU of 6itl by Molmil
Crystal structure of malate dehydrogenase from Mannheimia succiniciproducens in complex with NAD
Descriptor: GLYCEROL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Seo, H, Kim, K.-J.
Deposit date:2018-11-23
Release date:2019-11-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase.
Nat Commun, 11, 2020
6IHD
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BU of 6ihd by Molmil
Crystal structure of Malate dehydrogenase from Metallosphaera sedula
Descriptor: 2-ETHOXYETHANOL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Lee, D, Kim, K.J.
Deposit date:2018-09-29
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and biochemical characterization of malate dehydrogenase from Metallosphaera sedula
Biochem. Biophys. Res. Commun., 509, 2019
6IHE
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Crystal structure of Malate dehydrogenase from Metallosphaera sedula
Descriptor: 1,2-ETHANEDIOL, D-MALATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Lee, D, Kim, K.J.
Deposit date:2018-09-29
Release date:2019-02-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and biochemical characterization of malate dehydrogenase from Metallosphaera sedula
Biochem. Biophys. Res. Commun., 509, 2019
6ITK
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BU of 6itk by Molmil
Crystal structure of malate dehydrogenase from Corynebacterium glutamicum ATCC 13032 in complex with NAD and malate
Descriptor: (2S)-2-hydroxybutanedioic acid, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Seo, H, Kim, K.-J.
Deposit date:2018-11-23
Release date:2019-11-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase.
Nat Commun, 11, 2020
1PZH
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BU of 1pzh by Molmil
T.gondii LDH1 ternary complex with NAD and oxalate
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXALATE ION, lactate dehydrogenase
Authors:Kavanagh, K.L, Elling, R.A, Wilson, D.K.
Deposit date:2003-07-10
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
3P7M
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BU of 3p7m by Molmil
Structure of putative lactate dehydrogenase from Francisella tularensis subsp. tularensis SCHU S4
Descriptor: Malate dehydrogenase, PHOSPHATE ION
Authors:Osinski, T, Cymborowski, M, Zimmerman, M.D, Gordon, E, Grimshaw, S, Skarina, T, Chruszcz, M, Savchenko, A, Anderson, W, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-10-12
Release date:2010-10-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of putative lactate dehydrogenase from Francisella tularensis subsp. tularensis SCHU S4
To be Published
1PZE
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BU of 1pze by Molmil
T.gondii LDH1 apo form
Descriptor: lactate dehydrogenase
Authors:Kavanagh, K.L, Elling, R.A, Wilson, D.K.
Deposit date:2003-07-10
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
1PZF
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BU of 1pzf by Molmil
T.gondii LDH1 ternary complex with APAD+ and oxalate
Descriptor: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, OXALATE ION, lactate dehydrogenase
Authors:Kavanagh, K.L, Elling, R.A, Wilson, D.K.
Deposit date:2003-07-10
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
1PZG
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BU of 1pzg by Molmil
T.gondii LDH1 complexed with APAD and sulfate at 1.6 Angstroms
Descriptor: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, SULFATE ION, lactate dehydrogenase
Authors:Kavanagh, K.L, Elling, R.A, Wilson, D.K.
Deposit date:2003-07-10
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
6MVA
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BU of 6mva by Molmil
LDHA structure in complex with inhibitor 14
Descriptor: (6R)-6-(3-aminophenyl)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Eigenbrot, C.E, Ultsch, M, Wei, B.
Deposit date:2018-10-24
Release date:2019-10-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structure-based Optimization of Potent, Cell-Active Hydroxylactam Inhibitors of Lactate Dehydrogenase
To Be Published
3OM9
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BU of 3om9 by Molmil
T. Gondii bradyzoite-specific LDH (LDH1) in complex with NAD and OXQ
Descriptor: 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID, Lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Susko, M.S, Wilson, D.K.
Deposit date:2010-08-26
Release date:2010-10-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:T.Gondii bradyzoite-specific LDH (LDH1) in complex with NAD and OXQ
To be Published
6J9D
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BU of 6j9d by Molmil
Babesia microti lactate dehydrogenase R99A (BmLDHR99A)
Descriptor: L-lactate dehydrogenase
Authors:Yu, L.
Deposit date:2019-01-22
Release date:2019-10-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Crystal structures ofBabesia microtilactate dehydrogenase BmLDH reveal a critical role for Arg99 in catalysis.
Faseb J., 33, 2019
6JML
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BU of 6jml by Molmil
Re-refined structure of R-state L-lactate dehydrogenase fromLactobacillus casei
Descriptor: L-lactate dehydrogenase, SULFATE ION
Authors:Arai, K, Miyanaga, A, Uchikoba, H, Fushinobu, S, Taguchi, H.
Deposit date:2019-03-12
Release date:2020-05-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of penta mutant of L-lactate dehydrogenase from Lactobacillus casei
To Be Published
3PQE
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BU of 3pqe by Molmil
Crystal structure of L-lactate dehydrogenase from Bacillus subtilis with H171C mutation
Descriptor: L-lactate dehydrogenase
Authors:Zhang, Y, Garavito, R.M.
Deposit date:2010-11-26
Release date:2011-12-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of L-lactate dehydrogenase from Bacillus subtilis with H171C mutation
To be Published
3PQF
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BU of 3pqf by Molmil
Crystal structure of L-lactate dehydrogenase from Bacillus subtilis mutation H171C complexed with NAD+
Descriptor: L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Zhang, Y, Garavito, R.M.
Deposit date:2010-11-26
Release date:2012-01-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Crystal structure of L-lactate dehydrogenase from Bacillus subtilis mutation H171C complexed with NAD+
To be Published
3PQD
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BU of 3pqd by Molmil
Crystal structure of L-lactate dehydrogenase from Bacillus subtilis complexed with FBP and NAD+
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Zhang, Y, Garavito, R.M.
Deposit date:2010-11-26
Release date:2012-01-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.376 Å)
Cite:Crystal structure of L-lactate dehydrogenase from Bacillus subtilis complexed with FBP and NAD+
To be Published
1GUZ
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BU of 1guz by Molmil
Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases
Descriptor: MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Dalhus, B, Sarinen, M, Sauer, U.H, Eklund, P, Johansson, K, Karlsson, A, Ramaswamy, S, Bjork, A, Synstad, B, Naterstad, K, Sirevag, R, Eklund, H.
Deposit date:2002-02-04
Release date:2002-02-21
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases
J.Mol.Biol., 318, 2002
1SEV
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BU of 1sev by Molmil
Mature and translocatable forms of glyoxysomal malate dehydrogenase have different activities and stabilities but similar crystal structures
Descriptor: Malate dehydrogenase, glyoxysomal precursor
Authors:Cox, B.R, Chit, M.M, Weaver, T.M, Bailey, J, Gietl, C, Bell, E, Banaszak, L.J.
Deposit date:2004-02-18
Release date:2005-01-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Organelle and translocatable forms of glyoxysomal malate dehydrogenase. The effect of the N-terminal presequence
Febs J., 272, 2005
5KKC
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l-lactate dehydrogenase from rabbit muscle with the inhibitor 6DHNAD
Descriptor: L-lactate dehydrogenase A chain, SULFATE ION, [[(2~{R},3~{S},4~{R},5~{R})-5-(5-aminocarbonyl-2~{H}-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate
Authors:Meneely, K.M, Moran, G.R, Lamb, A.L.
Deposit date:2016-06-21
Release date:2016-11-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.859 Å)
Cite:Ligand binding phenomena that pertain to the metabolic function of renalase.
Arch.Biochem.Biophys., 612, 2016

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