Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4GUU
DownloadVisualize
BU of 4guu by Molmil
Crystal structure of LSD2-NPAC with tranylcypromine
Descriptor: Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, ZINC ION, ...
Authors:Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GU0
DownloadVisualize
BU of 4gu0 by Molmil
Crystal structure of LSD2 with H3
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3, Lysine-specific histone demethylase 1B, ...
Authors:Chen, F, Yang, H, Dong, Z, Fang, J, Zhu, T, Gong, W, Xu, Y.
Deposit date:2012-08-29
Release date:2013-02-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.103 Å)
Cite:Structural insight into substrate recognition by histone demethylase LSD2/KDM1b
Cell Res., 23, 2013
4HSU
DownloadVisualize
BU of 4hsu by Molmil
Crystal structure of LSD2-NPAC with H3(1-26)in space group P21
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3, Lysine-specific histone demethylase 1B, ...
Authors:Chen, F, Dong, Z, Fang, J, Xu, Y.
Deposit date:2012-10-30
Release date:2013-02-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.988 Å)
Cite:Structural insight into substrate recognition by histone demethylase LSD2/KDM1b.
Cell Res., 23, 2013
4II1
DownloadVisualize
BU of 4ii1 by Molmil
Crystal structure of the zinc finger of ZGPAT
Descriptor: UNKNOWN ATOM OR ION, ZINC ION, Zinc finger CCCH-type with G patch domain-containing protein
Authors:Bian, C, Tempel, W, Dong, A, Chao, X, Fu, M, Wernimont, A.K, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2012-12-19
Release date:2013-02-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of the zinc finger of ZGPAT
to be published
4L58
DownloadVisualize
BU of 4l58 by Molmil
Crystal structure of the MLL5 PHD finger in complex with H3K4me3
Descriptor: Histone H3 peptide, Histone-lysine N-methyltransferase MLL5, ZINC ION
Authors:Tong, Q, Ali, M, Kutateladze, T.G.
Deposit date:2013-06-10
Release date:2013-06-26
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Molecular basis for chromatin binding and regulation of MLL5.
Proc.Natl.Acad.Sci.USA, 110, 2013
4L7X
DownloadVisualize
BU of 4l7x by Molmil
Crystal structure of the DIDO PHD finger in complex with H3K4me3
Descriptor: Death-inducer obliterator 1, Histone H3 peptide, ZINC ION
Authors:Tong, Q, Gatchalian, J, Kutateladze, T.G.
Deposit date:2013-06-14
Release date:2013-07-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Dido3 PHD Modulates Cell Differentiation and Division.
Cell Rep, 4, 2013
2M3H
DownloadVisualize
BU of 2m3h by Molmil
Structure of Dido PHD domain
Descriptor: Death-inducer obliterator 1, ZINC ION
Authors:Santiveri, C.M, Perez-Canadillas, J.M, Jimenez, M.
Deposit date:2013-01-19
Release date:2013-08-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure note: PHD domain from death inducer obliterator protein and its interaction with H3K4me3.
J.Biomol.Nmr, 56, 2013
4LLB
DownloadVisualize
BU of 4llb by Molmil
Crystal Structure of MOZ double PHD finger histone H3K14ac complex
Descriptor: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION
Authors:Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M.
Deposit date:2013-07-09
Release date:2013-10-16
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.
Nucleic Acids Res., 42, 2014
4LKA
DownloadVisualize
BU of 4lka by Molmil
Crystal Structure of MOZ double PHD finger histone H3K9ac complex
Descriptor: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION
Authors:Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M.
Deposit date:2013-07-07
Release date:2013-10-16
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.
Nucleic Acids Res., 42, 2014
4LJN
DownloadVisualize
BU of 4ljn by Molmil
Crystal Structure of MOZ double PHD finger
Descriptor: Histone acetyltransferase KAT6A, ZINC ION
Authors:Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M.
Deposit date:2013-07-05
Release date:2013-10-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.
Nucleic Acids Res., 42, 2014
4LK9
DownloadVisualize
BU of 4lk9 by Molmil
Crystal Structure of MOZ double PHD finger histone H3 tail complex
Descriptor: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION
Authors:Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M.
Deposit date:2013-07-07
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.
Nucleic Acids Res., 42, 2014
4C1Q
DownloadVisualize
BU of 4c1q by Molmil
Crystal structure of the PRDM9 SET domain in complex with H3K4me2 and AdoHcy.
Descriptor: GLYCEROL, HISTONE H3.1, HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9, ...
Authors:Mathioudakis, N, Cusack, S, Kadlec, J.
Deposit date:2013-08-13
Release date:2013-10-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Basis for the Regulation of the H3K4 Methyltransferase Activity of Prdm9.
Cell Rep., 5, 2013
4MZH
DownloadVisualize
BU of 4mzh by Molmil
Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2s) peptide
Descriptor: MAGNESIUM ION, Peptide from Histone H3.2, Spindlin-1
Authors:Su, X, Ding, X, Li, H.
Deposit date:2013-09-30
Release date:2014-03-26
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1
Genes Dev., 28, 2014
4MZF
DownloadVisualize
BU of 4mzf by Molmil
Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2a) peptide
Descriptor: CHLORIDE ION, MAGNESIUM ION, Peptide from Histone H3.2, ...
Authors:Su, X, Ding, X, Li, H.
Deposit date:2013-09-30
Release date:2014-03-26
Method:X-RAY DIFFRACTION (2.098 Å)
Cite:Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1
Genes Dev., 28, 2014
4MZG
DownloadVisualize
BU of 4mzg by Molmil
Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ...
Authors:Su, X, Ding, X, Li, H.
Deposit date:2013-09-30
Release date:2014-03-26
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1
Genes Dev., 28, 2014
4UY4
DownloadVisualize
BU of 4uy4 by Molmil
1.86 A structure of human Spindlin-4 protein in complex with histone H3K4me3 peptide
Descriptor: GLYCEROL, HISTONE H3K4ME3, SPINDLIN-4
Authors:Talon, R, Gileadi, C, Johansson, C, Burgess-Brown, N, Shrestha, L, von Delft, F, Krojer, T, Fairhead, M, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U.
Deposit date:2014-08-28
Release date:2014-09-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.862 Å)
Cite:1.86 A Structure of Human Spindlin-4 Protein in Complex with Histone H3K4Me3 Peptide
To be Published
4U7P
DownloadVisualize
BU of 4u7p by Molmil
Crystal structure of DNMT3A-DNMT3L complex
Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Wang, L, Guo, X, Li, J, Xiao, J, Yin, X, He, S, Wang, J, Xu, Y.
Deposit date:2014-07-31
Release date:2014-11-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.821 Å)
Cite:Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
Nature, 517, 2015
4U7T
DownloadVisualize
BU of 4u7t by Molmil
Crystal structure of DNMT3A-DNMT3L in complex with histone H3
Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Guo, X, Wang, L, Yin, X, Li, J, Xiao, J, He, S, Wang, J, Xu, Y.
Deposit date:2014-07-31
Release date:2014-11-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
Nature, 517, 2015
4QL1
DownloadVisualize
BU of 4ql1 by Molmil
Crystal structure of human WDR5 in complex with compound OICR-9429
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, N-(4-(4-methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide, ...
Authors:Dong, A, Dombrovski, L, Walker, J.R, Getlik, M, Kuznetsova, E, Smil, D, Barsyte, D, Li, F, Poda, G, Senisterra, G, Marcellus, R, Al-Awar, R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Schapira, M, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2014-06-10
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Pharmacological targeting of the Wdr5-MLL interaction in C/EBP alpha N-terminal leukemia.
Nat.Chem.Biol., 11, 2015
4RIQ
DownloadVisualize
BU of 4riq by Molmil
Crystal structure of DPY-30 dimerization/docking domain in complex with Ash2L Sdc1-DPY-30 Interacting region (SDI)
Descriptor: Protein dpy-30 homolog, SULFATE ION, Set1/Ash2 histone methyltransferase complex subunit ASH2
Authors:Tremblay, V, Couture, J.-F.
Deposit date:2014-10-07
Release date:2014-12-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.231 Å)
Cite:Molecular Basis for DPY-30 Association to COMPASS-like and NURF Complexes.
Structure, 22, 2014
2MUM
DownloadVisualize
BU of 2mum by Molmil
Solution structure of the PHD domain of Yeast YNG2
Descriptor: Chromatin modification-related protein YNG2, ZINC ION
Authors:Taeb, S, Kaustov, L, Lemak, A, Farhadi, S, Sheng, Y.
Deposit date:2014-09-12
Release date:2014-12-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of the PHD domain of Yeast YNG2
To be Published
4UF0
DownloadVisualize
BU of 4uf0 by Molmil
Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid.
Descriptor: 1,2-ETHANEDIOL, 2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid, FE (II) ION, ...
Authors:Srikannathasan, V, Johansson, C, Gileadi, C, Tobias, K, Kopec, J, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.
Deposit date:2014-12-22
Release date:2015-01-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development.
Nat.Chem.Biol., 12, 2016
4UXN
DownloadVisualize
BU of 4uxn by Molmil
LSD1(KDM1A)-CoREST in complex with Z-Pro derivative of MC2580
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1, ...
Authors:Rodriguez, V, Valente, S, Stazi, G, Lucidi, A, Mercurio, C, Vianello, P, Ciossani, G, Mattevi, A, Botrugno, O.A, Dessanti, P, Minucci, S, Varasi, M, Mai, A.
Deposit date:2014-08-27
Release date:2015-02-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Pyrrole- and Indole-Containing Tranylcypromine Derivatives as Novel Lysine-Specific Demethylase 1 Inhibitors Active on Cancer Cells
Chemmedchem, 6, 2015
5A1F
DownloadVisualize
BU of 5a1f by Molmil
Crystal structure of the catalytic domain of PLU1 in complex with N-oxalylglycine.
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, LYSINE-SPECIFIC DEMETHYLASE 5B, ...
Authors:Srikannathasan, V, Johansson, C, Strain-Damerell, C, Gileadi, C, Szykowska, A, Kupinska, K, Kopec, J, Krojer, T, Steuber, H, von Delft, F, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U.
Deposit date:2015-04-29
Release date:2015-05-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development.
Nat.Chem.Biol., 12, 2016
5A3P
DownloadVisualize
BU of 5a3p by Molmil
Crystal structure of the catalytic domain of human PLU1 (JARID1B).
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, LYSINE-SPECIFIC DEMETHYLASE 5B, ...
Authors:Nowak, R, Srikannathasan, V, Johansson, C, Gileadi, C, Tallant, C, Kupinska, K, Strain-Damerell, C, Szykowska, A, von Delft, F, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U.
Deposit date:2015-06-02
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.008 Å)
Cite:Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development.
Nat.Chem.Biol., 12, 2016

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon