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2YBA
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Crystal structure of Nurf55 in complex with histone H3
分子名称: HISTONE H3, PROBABLE HISTONE-BINDING PROTEIN CAF1
著者Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H.
登録日2011-03-02
公開日2011-05-11
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks
Mol.Cell, 42, 2011
2YB8
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Crystal structure of Nurf55 in complex with Su(z)12
分子名称: POLYCOMB PROTEIN SU(Z)12, PROBABLE HISTONE-BINDING PROTEIN CAF1, SULFATE ION
著者Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H.
登録日2011-03-02
公開日2011-05-18
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks.
Mol.Cell, 42, 2011
2KYX
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Solution structure of the RRM domain of CYP33
分子名称: Peptidyl-prolyl cis-trans isomerase E
著者Park, S, Bushweller, J.H.
登録日2010-06-09
公開日2010-08-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression .
Biochemistry, 49, 2010
2KU7
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Solution structure of MLL1 PHD3-Cyp33 RRM chimeric protein
分子名称: MLL1 PHD3-Cyp33 RRM chimeric protein
著者Song, J, Wang, Z, Patel, D.
登録日2010-02-12
公開日2010-07-07
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
2KYU
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The solution structure of the PHD3 finger of MLL
分子名称: Histone-lysine N-methyltransferase MLL, ZINC ION
著者Park, S, Bushweller, J.H.
登録日2010-06-08
公開日2010-08-25
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression.
Biochemistry, 49, 2010
4U7P
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Crystal structure of DNMT3A-DNMT3L complex
分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Wang, L, Guo, X, Li, J, Xiao, J, Yin, X, He, S, Wang, J, Xu, Y.
登録日2014-07-31
公開日2014-11-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.821 Å)
主引用文献Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
Nature, 517, 2015
4U7T
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Crystal structure of DNMT3A-DNMT3L in complex with histone H3
分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Guo, X, Wang, L, Yin, X, Li, J, Xiao, J, He, S, Wang, J, Xu, Y.
登録日2014-07-31
公開日2014-11-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
Nature, 517, 2015
6LUK
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Crystal structure of the SAMD1 SAM domain in another crystal form
分子名称: Atherin, SULFATE ION
著者Cao, Y, Zhou, Y, Wang, Z.
登録日2020-01-29
公開日2021-02-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.054 Å)
主引用文献The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.
Sci Adv, 7, 2021
6LUI
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Crystal structure of the SAMD1 WH domain and DNA complex
分子名称: Atherin, DNA (5'-D(*AP*CP*CP*TP*GP*CP*GP*CP*AP*CP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*GP*TP*GP*CP*GP*CP*AP*GP*GP*T)-3')
著者Zhou, Y, Cao, Y, Wang, Z.
登録日2020-01-29
公開日2021-02-03
最終更新日2021-07-07
実験手法X-RAY DIFFRACTION (1.781 Å)
主引用文献The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.
Sci Adv, 7, 2021
6LUJ
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Crystal structure of the SAMD1 SAM domain
分子名称: Atherin, SULFATE ION
著者Cao, Y, Zhou, Y, Wang, Z.
登録日2020-01-29
公開日2021-02-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.
Sci Adv, 7, 2021
3N9M
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ceKDM7A from C.elegans, alone
分子名称: FE (II) ION, Putative uncharacterized protein, ZINC ION
著者Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y.
登録日2010-05-31
公開日2010-06-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.493 Å)
主引用文献Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
3N9P
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ceKDM7A from C.elegans, complex with H3K4me3K27me2 peptide and NOG
分子名称: FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ...
著者Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y.
登録日2010-05-31
公開日2010-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.388 Å)
主引用文献Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
3N9N
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ceKDM7A from C.elegans, complex with H3K4me3K9me2 peptide and NOG
分子名称: FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ...
著者Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y.
登録日2010-05-31
公開日2010-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
7CFP
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Crystal structure of WDR5 in complex with a H3Q5ser peptide
分子名称: H3Q5ser peptide, SEROTONIN, WD repeat-containing protein 5
著者Zhao, J, Zhang, X, Zang, J.
登録日2020-06-27
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the recognition of histone H3Q5 serotonylation by WDR5.
Sci Adv, 7, 2021
7CFQ
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Crystal structure of WDR5 in complex with H3K4me3Q5ser peptide
分子名称: 1,2-ETHANEDIOL, GLYCEROL, H3K4me3Q5ser peptide, ...
著者Zhao, J, Zhang, X, Zang, J.
登録日2020-06-27
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the recognition of histone H3Q5 serotonylation by WDR5.
Sci Adv, 7, 2021
5WXG
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BU of 5wxg by Molmil
Structure of TAF PHD finger domain binds to H3(1-15)K4ac
分子名称: Histone H3K4ac, MAGNESIUM ION, Transcription initiation factor TFIID subunit 3, ...
著者Zhao, S, Li, H.
登録日2017-01-07
公開日2017-08-16
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (1.703 Å)
主引用文献Kinetic and high-throughput profiling of epigenetic interactions by 3D-carbene chip-based surface plasmon resonance imaging technology
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5XVW
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BU of 5xvw by Molmil
Crystal structure of AL2 PAL domain in complex with AtRing1a distal site
分子名称: AtRing1a distal binding site, PHD finger protein ALFIN-LIKE 2
著者Peng, L, Wang, L.L, Huang, Y.
登録日2017-06-28
公開日2018-07-04
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
5XVL
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BU of 5xvl by Molmil
Crystal structure of AL2 PAL domain
分子名称: PHD finger protein ALFIN-LIKE 2, SULFATE ION
著者Peng, L, Wang, L.L, Huang, Y.
登録日2017-06-28
公開日2018-07-04
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.629 Å)
主引用文献Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
5XVJ
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Crystal structure of AL7 PAL domain
分子名称: PHD finger protein ALFIN-LIKE 7, SULFATE ION
著者Peng, L, Wang, L.L, Huang, Y.
登録日2017-06-28
公開日2018-07-04
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
5Y21
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BU of 5y21 by Molmil
Crystal structure of AL2 PAL domain in complex with AtRing1a proximal site
分子名称: AtRing1a proximal binding site peptide, PHD finger protein ALFIN-LIKE 2
著者Peng, L, Wang, L.L, Huang, Y.
登録日2017-07-22
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.769 Å)
主引用文献Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
5Y53
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Crystal structure of AL2 PAL domain in complex with AtBMI1b binding site
分子名称: AtBMI1b binding site, PHD finger protein ALFIN-LIKE 2
著者Peng, L, Wang, L.L, Huang, Y.
登録日2017-08-07
公開日2018-08-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
5YVX
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Crystal structure of SDG8 CW domain in complex with H3K4me1 peptide
分子名称: H3K4me1, Histone-lysine N-methyltransferase ASHH2, ZINC ION
著者Liu, Y, Huang, Y.
登録日2017-11-27
公開日2018-03-14
最終更新日2018-05-09
実験手法X-RAY DIFFRACTION (1.591 Å)
主引用文献Uncovering the mechanistic basis for specific recognition of monomethylated H3K4 by the CW domain ofArabidopsishistone methyltransferase SDG8.
J. Biol. Chem., 293, 2018
5C0M
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Crystal structure of SGF29 tandem tudor domain in complex with a Carba containing peptide
分子名称: Carba-containing peptide, GLYCEROL, SAGA-associated factor 29 homolog, ...
著者Dong, A, Xu, C, Tempel, W, Cerovina, T, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-06-12
公開日2015-07-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins.
Nat Commun, 6, 2015
7OCB
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Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-2N-[2-(dimethylamino)ethyl]-6-methoxy-4N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamine, CHLORIDE ION, ...
著者Johansson, C, Krojer, T, Park, K, Xiong, Y, Jin, J, Oppermann, U.
登録日2021-04-26
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B
To Be Published
6E2H
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Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30
分子名称: Protein dpy-30 homolog, Set1/Ash2 histone methyltransferase complex subunit ASH2
著者Joshi, M, Brunzelle, J.S, Couture, J.F.
登録日2018-07-11
公開日2018-08-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.236 Å)
主引用文献Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation.
Structure, 26, 2018

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