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7DY6
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BU of 7dy6 by Molmil
A refined cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA
Descriptor: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lin, W.
Deposit date:2021-01-20
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:A unique binding between SspA and RNAP beta' NTH across low-GC Gram-negative bacteria facilitates SspA-mediated transcription regulation.
Biochem.Biophys.Res.Commun., 583, 2021
7CKQ
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BU of 7ckq by Molmil
The cryo-EM structure of B. subtilis BmrR transcription activation complex
Descriptor: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Fang, C.L, Zhang, Y.
Deposit date:2020-07-18
Release date:2020-12-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription.
Nat Commun, 11, 2020
7CHW
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BU of 7chw by Molmil
Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo)
Descriptor: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lin, W, Feng, Y.
Deposit date:2020-07-06
Release date:2020-08-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Structural basis for transcription inhibition by E. coli SspA
Nucleic Acids Res., 2020
7C97
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BU of 7c97 by Molmil
Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA
Descriptor: DNA (63-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lin, W, Feng, Y.
Deposit date:2020-06-05
Release date:2020-08-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Structural basis for transcription inhibition by E. coli SspA
Nucleic Acids Res., 2020
7C17
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BU of 7c17 by Molmil
The cryo-EM structure of E. coli CueR transcription activation complex with fully duplex promoter DNA
Descriptor: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Fang, C.L, Zhang, Y.
Deposit date:2020-05-02
Release date:2020-09-30
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.22 Å)
Cite:CueR activates transcription through a DNA distortion mechanism.
Nat.Chem.Biol., 17, 2021
7BEG
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BU of 7beg by Molmil
Structures of class I bacterial transcription complexes
Descriptor: Class I pacrA promoter non-template DNA, Class I pacrA promoter template DNA, DNA-directed RNA polymerase subunit alpha, ...
Authors:Ye, F.Z, Hao, M, Zhang, X.D.
Deposit date:2020-12-23
Release date:2021-12-01
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
Adv Sci, 9, 2022
7BEF
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BU of 7bef by Molmil
Structures of class II bacterial transcription complexes
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Hao, M, Ye, F.Z, Zhang, X.D.
Deposit date:2020-12-23
Release date:2021-12-01
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
Adv Sci, 9, 2022
6XLM
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BU of 6xlm by Molmil
Cryo-EM structure of E.coli RNAP-DNA elongation complex 1 (RDe1) in EcmrR-dependent transcription
Descriptor: 9-nt RNA transcript, CHAPSO, DNA-directed RNA polymerase subunit alpha, ...
Authors:Yang, Y, Liu, C, Liu, B.
Deposit date:2020-06-28
Release date:2021-04-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XLL
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BU of 6xll by Molmil
Cryo-EM structure of E. coli RNAP-promoter initial transcribing complex with 5-nt RNA transcript (RPitc-5nt)
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yang, Y, Liu, C, Liu, B.
Deposit date:2020-06-28
Release date:2021-04-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XLJ
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BU of 6xlj by Molmil
Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 4-nt RNA transcript (EcmrR-RPitc-4nt)
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yang, Y, Liu, C, Liu, B.
Deposit date:2020-06-28
Release date:2021-04-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XL9
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BU of 6xl9 by Molmil
Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 3-nt RNA transcript (EcmrR-RPitc-3nt)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Yang, Y, Liu, C, Shi, W, Liu, B.
Deposit date:2020-06-28
Release date:2021-04-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XL5
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BU of 6xl5 by Molmil
Cryo-EM structure of EcmrR-RNAP-promoter open complex (EcmrR-RPo)
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yang, Y, Liu, C, Liu, B.
Deposit date:2020-06-28
Release date:2021-04-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XH8
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BU of 6xh8 by Molmil
CueR-transcription activation complex with RNA transcript
Descriptor: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Shi, W, Yang, Y.
Deposit date:2020-06-18
Release date:2021-04-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of copper-efflux-regulator-dependent transcription activation.
Iscience, 24, 2021
6XH7
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BU of 6xh7 by Molmil
CueR-TAC without RNA
Descriptor: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Shi, W, Yang, Y.
Deposit date:2020-06-18
Release date:2021-04-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of copper-efflux-regulator-dependent transcription activation.
Iscience, 24, 2021
6WOY
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BU of 6woy by Molmil
Thermus thermophilus RNA polymerase initially transcribing complex with 3'dCTP
Descriptor: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*G)-3'), ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2020-04-26
Release date:2020-06-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases.
Nat Commun, 12, 2021
6WOX
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BU of 6wox by Molmil
Thermus thermophilus RNA polymerase initially transcribing complex with 2'dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*G)-3'), ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2020-04-26
Release date:2020-06-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases.
Nat Commun, 12, 2021
6WMU
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BU of 6wmu by Molmil
E. coli RNAPs70-SspA-gadA DNA complex
Descriptor: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ...
Authors:Travis, B.A, Brennan, R.G, Schumacher, M.A.
Deposit date:2020-04-21
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
6WMT
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BU of 6wmt by Molmil
F. tularensis RNAPs70-(MglA-SspA)-ppGpp-PigR-iglA DNA complex
Descriptor: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ...
Authors:Travis, B.A, Brennan, R.G, Schumacher, M.A.
Deposit date:2020-04-21
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.43 Å)
Cite:Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
6WMR
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BU of 6wmr by Molmil
F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex
Descriptor: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ...
Authors:Travis, B.A, Brennan, R.G, Schumacher, M.A.
Deposit date:2020-04-21
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
6VW0
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BU of 6vw0 by Molmil
Mycobacterium tuberculosis RNAP S456L mutant open promoter complex
Descriptor: DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lilic, M, Boyaci, H, Chen, J, Darst, S.A, Campbell, E.A.
Deposit date:2020-02-18
Release date:2020-10-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VVZ
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BU of 6vvz by Molmil
Mycobacterium tuberculosis RNAP S456L mutant transcription initiation intermediate structure with Sorangicin
Descriptor: DNA (62-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lilic, M, Boyaci, H, Chen, J, Darst, S.A, Campbell, E.A.
Deposit date:2020-02-18
Release date:2020-10-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VVY
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BU of 6vvy by Molmil
Mycobacterium tuberculosis WT RNAP transcription open promoter complex with Sorangicin
Descriptor: DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lilic, M, Boyaci, H, Chen, J, Darst, S.A, Campbell, E.A.
Deposit date:2020-02-18
Release date:2020-10-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VVX
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BU of 6vvx by Molmil
Mycobacterium tuberculosis WT RNAP transcription initiation intermediate structure with Sorangicin
Descriptor: DNA (63-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lilic, M, Boyaci, H, Chen, J, Campbell, E.A, Darst, S.A.
Deposit date:2020-02-18
Release date:2020-10-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VVV
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BU of 6vvv by Molmil
Crystal structure of a Mycobacterium smegmatis transcription initiation complex with Rifampicin-resistant RNA polymerase
Descriptor: DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lilic, M, Darst, S.A, Campbell, E.A.
Deposit date:2020-02-18
Release date:2020-10-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VVT
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BU of 6vvt by Molmil
Crystal structure of a Mycobacterium smegmatis transcription initiation complex with Rifampicin-resistant RNA polymerase and antibiotic Sorangicin
Descriptor: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ...
Authors:Lilic, M, Darst, S.A, Campbell, E.A.
Deposit date:2020-02-18
Release date:2020-10-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Proc.Natl.Acad.Sci.USA, 117, 2020

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PDB entries from 2024-03-27

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