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8G7Q
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BU of 8g7q by Molmil
Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the near-cognate AUG codon (Structure II)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2023-02-16
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance
Nat.Struct.Mol.Biol., 2024
2BVN
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BU of 2bvn by Molmil
E. coli EF-Tu:GDPNP in complex with the antibiotic enacyloxin IIa
Descriptor: ELONGATION FACTOR TU, ENACYLOXIN IIA, MAGNESIUM ION, ...
Authors:Parmeggiani, A, Krab, I.M, Watanabe, T, Nielsen, R.C, Dahlberg, C, Nyborg, J, Nissen, P.
Deposit date:2005-06-30
Release date:2005-09-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics.
J.Biol.Chem., 281, 2006
1JNY
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BU of 1jny by Molmil
Crystal structure of Sulfolobus solfataricus elongation factor 1 alpha in complex with GDP
Descriptor: Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE
Authors:Vitagliano, L, Masullo, M, Sica, F, Zagari, A, Bocchini, V.
Deposit date:2001-07-26
Release date:2002-01-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with GDP reveals novel features in nucleotide binding and exchange.
EMBO J., 20, 2001
1QZD
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BU of 1qzd by Molmil
EF-Tu.kirromycin coordinates fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome
Descriptor: Elongation factor Tu
Authors:Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J.
Deposit date:2003-09-16
Release date:2003-11-04
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy
Nat.Struct.Biol., 10, 2003
2C77
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EF-Tu complexed with a GTP analog and the antibiotic GE2270 A
Descriptor: DI(HYDROXYETHYL)ETHER, ELONGATION FACTOR TU-B, MAGNESIUM ION, ...
Authors:Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P.
Deposit date:2005-11-18
Release date:2006-03-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry, 45, 2006
2C78
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EF-Tu complexed with a GTP analog and the antibiotic pulvomycin
Descriptor: (1S,2S,3E,5E,7E,10S,11S,12S)-12-[(2R,4E,6E,8Z,10R,12E,14E,16Z,18S,19Z)-10,18-DIHYDROXY-12,16,19-TRIMETHYL-11,22-DIOXOOX ACYCLODOCOSA-4,6,8,12,14,16,19-HEPTAEN-2-YL]-2,11-DIHYDROXY-1,10-DIMETHYL-9-OXOTRIDECA-3,5,7-TRIEN-1-YL 6-DEOXY-2,4-DI-O-METHYL-BETA-L-GALACTOPYRANOSIDE, ELONGATION FACTOR TU-A, MAGNESIUM ION, ...
Authors:Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P.
Deposit date:2005-11-18
Release date:2006-03-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry, 45, 2006
1R5O
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crystal structure analysis of sup35 complexed with GMPPNP
Descriptor: Eukaryotic peptide chain release factor GTP-binding subunit, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Kong, C, Song, H.
Deposit date:2003-10-11
Release date:2004-05-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe
Mol.Cell, 14, 2004
1R5B
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Crystal structure analysis of sup35
Descriptor: Eukaryotic peptide chain release factor GTP-binding subunit
Authors:Kong, C, Song, H.
Deposit date:2003-10-10
Release date:2004-05-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe
Mol.Cell, 14, 2004
1R5N
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BU of 1r5n by Molmil
Crystal Structure Analysis of sup35 complexed with GDP
Descriptor: Eukaryotic peptide chain release factor GTP-binding subunit, GUANOSINE-5'-DIPHOSPHATE
Authors:Kong, C, Song, H.
Deposit date:2003-10-10
Release date:2004-05-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe
Mol.Cell, 14, 2004
1LS2
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BU of 1ls2 by Molmil
Fitting of EF-Tu and tRNA in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome
Descriptor: Elongation Factor Tu, Phenylalanine transfer RNA
Authors:Valle, M, Sengupta, J, Swami, N.K, Grassucci, R.A, Burkhardt, N, Nierhaus, K.H, Agrawal, R.K, Frank, J.
Deposit date:2002-05-16
Release date:2002-06-26
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (16.799999 Å)
Cite:Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
1MJ1
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BU of 1mj1 by Molmil
FITTING THE TERNARY COMPLEX OF EF-Tu/tRNA/GTP AND RIBOSOMAL PROTEINS INTO A 13 A CRYO-EM MAP OF THE COLI 70S RIBOSOME
Descriptor: Elongation Factor Tu, L11 ribosomal protein, Phe-tRNA, ...
Authors:Stark, H, Rodnina, M.V, Wieden, H.-J, Zemlin, F, Wintermeyer, W, Vanheel, M.
Deposit date:2002-08-26
Release date:2002-11-01
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Ribosome Interactions of Aminoacyl-tRNA and Elongation Factor TU in the Codon Recognition Complex
Nat.Struct.Biol., 9, 2002
4V5R
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BU of 4v5r by Molmil
The crystal structure of EF-Tu and Trp-tRNA-Trp bound to a cognate codon on the 70S ribosome.
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V5S
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BU of 4v5s by Molmil
The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a cognate codon on the 70S ribosome.
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V6K
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BU of 4v6k by Molmil
Structural insights into cognate vs. near-cognate discrimination during decoding.
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Agirrezabala, X, Schreiner, E, Trabuco, L.G, Lei, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
Deposit date:2011-01-07
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (8.25 Å)
Cite:Structural insights into cognate versus near-cognate discrimination during decoding.
Embo J., 30, 2011
4V6L
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BU of 4v6l by Molmil
Structural insights into cognate vs. near-cognate discrimination during decoding.
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Agirrezabala, X, Schreiner, E, Trabuco, L.G, Lei, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
Deposit date:2011-01-07
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (13.2 Å)
Cite:Structural insights into cognate versus near-cognate discrimination during decoding.
Embo J., 30, 2011
4V5L
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BU of 4v5l by Molmil
The structure of EF-Tu and aminoacyl-tRNA bound to the 70S ribosome with a GTP analog
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Voorhees, R.M, Schmeing, T.M, Ramakrishnan, V.
Deposit date:2010-09-02
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Mechanism for Activation of GTP Hydrolysis on the Ribosome.
Science, 330, 2010
4V8Q
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BU of 4v8q by Molmil
Complex of SmpB, a tmRNA fragment and EF-Tu-GDP-Kirromycin with the 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Neubauer, C, Gillet, R, Kelley, A.C, Ramakrishnan, V.
Deposit date:2011-12-10
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Decoding in the absence of a codon by tmRNA and SmpB in the ribosome.
Science, 335, 2012
4V5P
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BU of 4v5p by Molmil
The crystal structure of EF-Tu and A9C-tRNA-Trp bound to a near- cognate codon on the 70S ribosome
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
5UYN
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BU of 5uyn by Molmil
70S ribosome bound with near-cognate ternary complex not base-paired to A site codon (Structure I-nc)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
5UYM
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BU of 5uym by Molmil
70S ribosome bound with cognate ternary complex base-paired to A site codon, closed 30S (Structure III)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
5UYQ
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BU of 5uyq by Molmil
70S ribosome bound with near-cognate ternary complex base-paired to A site codon, closed 30S (Structure III-nc)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
5UYL
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BU of 5uyl by Molmil
70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity.
Nature, 546, 2017
5UYP
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BU of 5uyp by Molmil
70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
5UYK
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BU of 5uyk by Molmil
70S ribosome bound with cognate ternary complex not base-paired to A site codon (Structure I)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
5WF0
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BU of 5wf0 by Molmil
70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fislage, M, Frank, J.
Deposit date:2017-07-11
Release date:2018-05-02
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018

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PDB entries from 2024-03-27

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