PDB: 83 resultsInfo pagesStatus searchChemie searchBIRD

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6ORU	Crystal structure of Bira from S. aureus in complex with a acylsulfamide analogue of biotinyl-5'-AMP Descriptor: Bifunctional ligase/repressor BirA, N-{[4-(6-amino-9H-purin-9-yl)butyl]sulfamoyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide Authors: Wilce, M.C.J, Cini, D. Deposit date: 2019-05-01 Release date: 2020-07-01 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.392 Å) Cite: Enhancing the stability of the sulfonamide linker of BPL inhibitors To Be Published
7DBS	Crystal Structure Of Biotin Protein Ligase From Leishmania Major in complex with Biotin Descriptor: BIOTIN, Biotin/lipoate protein ligase-like protein Authors: Rajak, M, Sundd, M. Deposit date: 2020-10-21 Release date: 2021-04-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Leishmania major biotin protein ligase forms a unique cross-handshake dimer. Acta Crystallogr D Struct Biol, 77, 2021
8CRI	Crystal structure of LplA1 in complex with lipoic acid (Listeria monocytogenes) Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, LIPOIC ACID, ... Authors: Dienemann, J.-N, Chen, S.-Y, Hitzenberger, M, Sievert, M.L, Hacker, S.M, Prigge, S.T, Zacharias, M, Groll, M, Sieber, S.A. Deposit date: 2023-03-08 Release date: 2023-06-07 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites. Angew.Chem.Int.Ed.Engl., 62, 2023
8CRJ	Crystal structure of LplA1 in complex with lipoyl-AMP (Listeria monocytogenes) Descriptor: 1,2-ETHANEDIOL, 5'-O-[(R)-({5-[(3R)-1,2-DITHIOLAN-3-YL]PENTANOYL}OXY)(HYDROXY)PHOSPHORYL]ADENOSINE, GLYCEROL, ... Authors: Dienemann, J.-N, Chen, S.-Y, Hitzenberger, M, Sievert, M.L, Hacker, S.M, Prigge, S.T, Zacharias, M, Groll, M, Sieber, S.A. Deposit date: 2023-03-08 Release date: 2023-06-07 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites. Angew.Chem.Int.Ed.Engl., 62, 2023
8CRL	Crystal structure of LplA1 in complex with the inhibitor C3 (Listeria monocytogenes) Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ... Authors: Dienemann, J.-N, Chen, S.-Y, Hitzenberger, M, Sievert, M.L, Hacker, S.M, Prigge, S.T, Zacharias, M, Groll, M, Sieber, S.A. Deposit date: 2023-03-08 Release date: 2023-06-07 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites. Angew.Chem.Int.Ed.Engl., 62, 2023
8ENI	Crystal structure of Staphylococcus aureus biotin protein ligase in complex with inhibitor Descriptor: 3-[4-(5-fluoro-4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)butyl]-5-methyl-1,3-benzoxazol-2(3H)-one, Bifunctional ligase/repressor BirA Authors: Wilce, M.C.J, Cini, D.A. Deposit date: 2022-09-30 Release date: 2022-11-30 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus. ACS Infect Dis, 4, 2018
8F8U	Bifunctional ligase/repressor BirA from Klebsiella pneumoniae (Domain Swapped Dimer) Descriptor: Bifunctional ligase/repressor BirA, IMIDAZOLE Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-11-22 Release date: 2022-11-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Bifunctional ligase/repressor BirA from Klebsiella pneumoniae (Domain Swapped Dimer) To be published
8FI3	Bifunctional ligase/repressor BirA from Klebsiella pneumoniae complexed with biotin (Domain Swapped Dimer) Descriptor: BIOTIN, Bifunctional ligase/repressor BirA Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-12-15 Release date: 2022-12-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Bifunctional ligase/repressor BirA from Klebsiella pneumoniae complexed with biotin (Domain Swapped Dimer) To be published

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