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2CVW
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BU of 2cvw by Molmil
Structures of Yeast Ribonucleotide Reductase I
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1, ...
Authors:Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVY
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BU of 2cvy by Molmil
Structures of Yeast Ribonucleotide Reductase I
Descriptor: 9-per peptide from Ribonucleoside-diphosphate reductase small chain 1, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1, ...
Authors:Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2EUD
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BU of 2eud by Molmil
Structures of Yeast Ribonucleotide Reductase I complexed with Ligands and Subunit Peptides
Descriptor: GEMCITABINE DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Dealwis, C, Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J.
Deposit date:2005-10-28
Release date:2006-03-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2WGH
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BU of 2wgh by Molmil
Human Ribonucleotide reductase R1 subunit (RRM1) in complex with dATP and Mg.
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Welin, R.M, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kragh-Nielsen, T, Kotzsch, A, Kotenyova, T, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Wisniewska, M, Nordlund, P.
Deposit date:2009-04-19
Release date:2009-05-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for Allosteric Regulation of Human Ribonucleotide Reductase by Nucleotide-Induced Oligomerization.
Nat.Struct.Mol.Biol., 18, 2011
2XAV
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BU of 2xav by Molmil
Ribonucleotide reductase Y731NO2Y and Y730F modified R1 subunit of E. coli
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Yokoyama, K, Uhlin, U, Stubbe, J.
Deposit date:2010-03-31
Release date:2010-04-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
2XAP
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BU of 2xap by Molmil
Ribonucleotide reductase Y731NO2Y modified R1 subunit of E. coli to 2. 1 A resolution
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Yokoyama, K, Uhlin, U, Stubbe, J.
Deposit date:2010-03-31
Release date:2010-04-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
2XAX
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BU of 2xax by Molmil
Ribonucleotide reductase Y730NO2Y and Y731A modified R1 subunit of E. coli
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Yokoyama, K, Uhlin, U, Stubbe, J.
Deposit date:2010-04-01
Release date:2010-04-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
2XAK
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BU of 2xak by Molmil
Ribonucleotide reductase Y730NO2Y modified R1 subunit of E. coli
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Yokoyama, K, Uhlin, U, Stubbe, J.
Deposit date:2010-03-31
Release date:2010-04-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
2XAW
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BU of 2xaw by Molmil
Ribonucleotide reductase Y730NO2Y and Y731F modified R1 subunit of E. coli
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Yokoyama, K, Uhlin, U, Stubbe, J.
Deposit date:2010-03-31
Release date:2010-04-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
2X0X
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BU of 2x0x by Molmil
Ribonucleotide reductase R1 subunit of E. coli to 2.3 A resolution
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA, SULFATE ION
Authors:Yokoyama, K, Uhlin, U, Stubbe, J.
Deposit date:2009-12-18
Release date:2010-01-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
2XAZ
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BU of 2xaz by Molmil
Ribonucleotide reductase Y730NO2Y and C439S modified R1 subunit of E. coli
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Yokoyama, K, Uhlin, U, Stubbe, J.
Deposit date:2010-04-01
Release date:2010-04-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
2XAY
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BU of 2xay by Molmil
Ribonucleotide reductase Y730NO2Y and C439A modified R1 subunit of E. coli
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Yokoyama, K, Uhlin, U, Stubbe, J.
Deposit date:2010-04-01
Release date:2010-04-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
2XO5
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BU of 2xo5 by Molmil
RIBONUCLEOTIDE REDUCTASE Y731NH2Y MODIFIED R1 SUBUNIT OF E. COLI
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Minnihan, E.C, Seyedsayamdost, M.R, Uhlin, U, Stubbe, J.
Deposit date:2010-08-09
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine- Substituted Escherichia Coli Ribonucleotide Reductases.
J.Am.Chem.Soc., 133, 2011
2XO4
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BU of 2xo4 by Molmil
RIBONUCLEOTIDE REDUCTASE Y730NH2Y MODIFIED R1 SUBUNIT OF E. COLI
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Minnihan, E.C, Seyedsayamdost, M.R, Uhlin, U, Stubbe, J.
Deposit date:2010-08-09
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine- Substituted Escherichia Coli Ribonucleotide Reductases.
J.Am.Chem.Soc., 133, 2011
2ZLF
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BU of 2zlf by Molmil
The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase
Descriptor: FTLDADF, Ribonucleoside-diphosphate reductase large chain 1
Authors:Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C.
Deposit date:2008-04-09
Release date:2008-08-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore
J.Med.Chem., 51, 2008
2ZLG
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BU of 2zlg by Molmil
The Structual Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase
Descriptor: (5R,9S,12S,15S,18S,21S)-21-benzyl-12,18-bis(carboxymethyl)-15-cyclohexyl-1-(9H-fluoren-9-yl)-4-methyl-9-(2-methylpropyl)-3,6,10,13,16,19-hexaoxo-5-phenyl-2-oxa-4,8,11,14,17,20-hexaazadocosan-22-oic acid, GLYCEROL, Ribonucleoside-diphosphate reductase large chain 1
Authors:Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C.
Deposit date:2008-04-09
Release date:2008-08-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore
J.Med.Chem., 51, 2008
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