6IEJ
 
 | | The C2 domain of cytosolic phospholipase A2 alpha bound to phosphatidylcholine | | Descriptor: | 1,2-dihexanoyl-sn-glycero-3-phosphocholine, CALCIUM ION, Cytosolic phospholipase A2, ... | | Authors: | Hirano, Y, Gao, Y.G, Stephenson, D.J, Vu, N.T, Malinina, L, Chalfant, C.E, Patel, D.J, Brown, R.E. | | Deposit date: | 2018-09-14 | | Release date: | 2019-05-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.206 Å) | | Cite: | Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase A2alpha.
Elife, 8, 2019
|
|
6KXT
 | | BON1-C2B | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Protein BONZAI 1, SULFATE ION | | Authors: | Wang, Q.C, Jiang, M.Q, Isupov, M.N, Sun, L.F, Wu, Y.K. | | Deposit date: | 2019-09-12 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Crystal Structure of an Arabidopsis Copine providing insights into this protein family
To be published
|
|
6LCY
 | | Crystal structure of Synaptotagmin-7 C2B in complex with IP6 | | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Synaptotagmin-7 | | Authors: | Zhang, Y, Zhang, X, Rao, F, Wang, C. | | Deposit date: | 2019-11-20 | | Release date: | 2021-03-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.301 Å) | | Cite: | 5-IP 7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
Nat Metab, 3, 2021
|
|
6EEL
 | |
6EI6
 | | CC2D1B coordinates ESRCT-III activity during the mitotic reformation of the nuclear envelope | | Descriptor: | Coiled-coil and C2 domain-containing protein 1-like, DI(HYDROXYETHYL)ETHER, SULFATE ION | | Authors: | Ventimiglia, L.N, Cuesta-Geijo, M.A, Martinelli, N, Caballe, A, Macheboeuf, P, Miguet, N, Parnham, I.M, Olmos, Y, Carlton, J.G, Weissehorn, W, martin-Serrano, J. | | Deposit date: | 2017-09-18 | | Release date: | 2018-10-10 | | Last modified: | 2018-12-19 | | Method: | X-RAY DIFFRACTION (2.461 Å) | | Cite: | CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope.
Dev. Cell, 47, 2018
|
|
7U4Q
 | |
7TUA
 | |
7TX9
 | | Human Synaptotagmin-1 C2B Y312F Ca2+ bound | | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Dominguez, M.J, Karmakar, S, Fuson, K.L, Sutton, R.B. | | Deposit date: | 2022-02-08 | | Release date: | 2023-03-29 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | Human Synaptotagmin-1 C2B Y312F Ca2+ bound
To Be Published
|
|
6EWP
 | | Mus musculus CEP120 third C2 domain (C2C) | | Descriptor: | Centrosomal protein of 120 kDa, HEXAETHYLENE GLYCOL | | Authors: | van Breugel, M, al-Jassar, C. | | Deposit date: | 2017-11-06 | | Release date: | 2018-05-02 | | Last modified: | 2018-06-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis.
Cell Rep, 23, 2018
|
|
6FB4
 | | human KIBRA C2 domain mutant C771A | | Descriptor: | GLYCEROL, PHOSPHATE ION, Protein KIBRA | | Authors: | Crennell, S.J, Posner, M.G, Bagby, S. | | Deposit date: | 2017-12-18 | | Release date: | 2018-05-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.415631 Å) | | Cite: | Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain.
J. Biol. Chem., 293, 2018
|
|
6FJC
 | | Human KIBRA C2 domain mutant C771A in complex with phosphatidylinositol 3,4,5-trisphosphate | | Descriptor: | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, GLYCEROL, Protein KIBRA, ... | | Authors: | Crennell, S.J, Posner, M.G, Bagby, S. | | Deposit date: | 2018-01-22 | | Release date: | 2018-05-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.598 Å) | | Cite: | Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain.
J. Biol. Chem., 293, 2018
|
|
6FJD
 | | Human KIBRA C2 domain mutant C771A in complex with phosphatidylinositol 4,5-bisphosphate | | Descriptor: | (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, GLYCEROL, Protein KIBRA, ... | | Authors: | Crennell, S.J, Posner, M.G, Bagby, S. | | Deposit date: | 2018-01-22 | | Release date: | 2018-05-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.898 Å) | | Cite: | Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain.
J. Biol. Chem., 293, 2018
|
|
6FD0
 | | Human KIBRA C2 domain mutant M734I S735A | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Protein KIBRA | | Authors: | Crennell, S.J, Posner, M.G, Bagby, S. | | Deposit date: | 2017-12-21 | | Release date: | 2018-05-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.64215851 Å) | | Cite: | Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain.
J. Biol. Chem., 293, 2018
|
|
6FLJ
 | |
6FLK
 | |
2FK9
 | | Human protein kinase C, eta | | Descriptor: | protein kinase C, eta type | | Authors: | Walker, J.R, Littler, D.R, Finerty Jr, P.J, MacKenzie, F, Newman, E.M, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-01-04 | | Release date: | 2006-01-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structure of human protein kinase C eta (PKCeta) C2 domain and identification of phosphorylation sites.
Biochem.Biophys.Res.Commun., 349, 2006
|
|
1TJX
 | | Crystallographic Identification of Ca2+ Coordination Sites in Synaptotagmin I C2B Domain | | Descriptor: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | | Authors: | Cheng, Y, Sequeira, S.M, Malinina, L, Tereshko, V, Sollner, T.H, Patel, D.J. | | Deposit date: | 2004-06-07 | | Release date: | 2004-11-23 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.04 Å) | | Cite: | Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain.
Protein Sci., 13, 2004
|
|
1TJM
 | | Crystallographic Identification of Sr2+ Coordination Site in Synaptotagmin I C2B Domain | | Descriptor: | GLYCEROL, STRONTIUM ION, Synaptotagmin I | | Authors: | Cheng, Y, Sequeira, S.M, Malinina, L, Tereshko, V, Sollner, T.H, Patel, D.J. | | Deposit date: | 2004-06-06 | | Release date: | 2004-09-28 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.18 Å) | | Cite: | Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain
Protein Sci., 13, 2004
|
|
1UGK
 | | Solution structure of the first C2 domain of synaptotagmin IV from human fetal brain (KIAA1342) | | Descriptor: | Synaptotagmin IV | | Authors: | Nagashima, T, Hayashi, F, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Matsuo, Y, Ohara, O, Nagase, T, Kikuno, R, Nakayama, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-16 | | Release date: | 2003-12-16 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the first C2 domain of synaptotagmin IV from human fetal brain (KIAA1342)
To be Published
|
|
1V27
 | |
1UOW
 | | Calcium binding domain C2B | | Descriptor: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | | Authors: | Cheng, Y, Sequeira, S.M, Sollner, T.H, Patel, D.J. | | Deposit date: | 2003-09-24 | | Release date: | 2004-09-16 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.04 Å) | | Cite: | Crystallographic Identification of Ca2+ and Sr2+ Coordination Sites in Synaptotagmin I C2B Domain
Protein Sci., 13, 2004
|
|
1UOV
 | | Calcium binding domain C2B | | Descriptor: | CALCIUM ION, GLYCEROL, SYNAPTOTAGMIN I | | Authors: | Cheng, Y, Sequeira, S.M, Sollner, T.H, Patel, D.J. | | Deposit date: | 2003-09-24 | | Release date: | 2004-09-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystallographic Identification of Ca2+ and Sr2+ Coordination Sites in Synaptotagmin I C2B Domain
Protein Sci., 13, 2004
|
|
1W15
 | | rat synaptotagmin 4 C2B domain in the presence of calcium | | Descriptor: | CALCIUM ION, CHLORIDE ION, SODIUM ION, ... | | Authors: | Dai, H, Shin, O.-H, Machius, M, Tomchick, D.R, Sudhof, T.C, Rizo, J. | | Deposit date: | 2004-06-16 | | Release date: | 2004-08-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Structural Basis for the Evolutionary Inactivation of Ca2+ Binding to Synaptotagmin 4
Nat.Struct.Mol.Biol., 11, 2004
|
|
1W16
 | | rat synaptotagmin 4 C2B domain in the absence of calcium | | Descriptor: | CHLORIDE ION, SODIUM ION, SYNAPTOTAGMIN IV | | Authors: | Dai, H, Shin, O.-H, Machius, M, Tomchick, D.R, Sudhof, T.C, Rizo, J. | | Deposit date: | 2004-06-16 | | Release date: | 2004-08-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis for the Evolutionary Inactivation of Ca2+ Binding to Synaptotagmin 4
Nat.Struct.Mol.Biol., 11, 2004
|
|
1WFJ
 | |
