PDB: 433 resultsInfo pagesStatus searchChemie searchBIRD

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3FQ9	Design of an insulin analog with enhanced receptor-binding selectivity. Rationale, structure, and therapeutic implications Descriptor: Insulin, ZINC ION Authors: Zhao, M, Wan, Z.L, Whittaker, L, Xu, B, Phillips, N, Katsoyannis, P, Whittaker, J, Weiss, M.A. Deposit date: 2009-01-07 Release date: 2009-08-04 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications. J.Biol.Chem., 284, 2009
3AIY	R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, REFINED AVERAGE STRUCTURE Descriptor: PHENOL, PROTEIN (INSULIN) Authors: O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. Deposit date: 1998-12-29 Release date: 2000-02-28 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure. J.Biomol.NMR, 16, 2000
3GF1	SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY Descriptor: INSULIN-LIKE GROWTH FACTOR I Authors: Cooke, R.M, Harvey, T.S, Campbell, I.D. Deposit date: 1991-01-24 Release date: 1993-04-15 Last modified: 2022-03-16 Method: SOLUTION NMR Cite: Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study. Biochemistry, 30, 1991
3GKY	The Structural Basis of an ER Stress-Associated Bottleneck in a Protein Folding Landscape Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Liu, M, Wan, Z.L, Chu, Y.C, Alddin, H, Klaproth, B, Weiss, M.A. Deposit date: 2009-03-11 Release date: 2009-03-24 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of a "nonfoldable" insulin: IMPAIRED FOLDING EFFICIENCY DESPITE NATIVE ACTIVITY. J.Biol.Chem., 284, 2009
8GSG	T3R3 form of Human insulin with single Zn Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Zhu, Z.L. Deposit date: 2022-09-06 Release date: 2023-03-15 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.05 Å) Cite: T3R3 insulin with single Zn To Be Published
5L3N	D11 bound [N29, S39_PQ]-IGF-II Descriptor: Insulin-like growth factor II Authors: Hexnerova, R. Deposit date: 2016-05-23 Release date: 2016-08-10 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5L3L	D11 bound IGF-II Descriptor: Insulin-like growth factor II Authors: Hexnerova, R. Deposit date: 2016-05-23 Release date: 2016-08-10 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5L3M	D11 bound [S39_PQ]-IGF-II Descriptor: Insulin-like growth factor II Authors: Hexnerova, R. Deposit date: 2016-05-23 Release date: 2016-08-10 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5LIS	Insulin solved by Native SAD from a dataset collected in one second Descriptor: Insulin Authors: Casanas, A, Finke, A, Wang, M. Deposit date: 2016-07-15 Release date: 2016-08-03 Last modified: 2016-09-28 Method: X-RAY DIFFRACTION (2.293 Å) Cite: EIGER detector: application in macromolecular crystallography. Acta Crystallogr D Struct Biol, 72, 2016
8HGZ	Crystal structure of insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: DeMirci, H, Ayan, E. Deposit date: 2022-11-16 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Comparative Study of High-Resolution LysB29(N epsilon-myristoyl) des(B30) Insulin Structures Display Novel Dynamic Causal Interrelations in Monomeric-Dimeric Motions Crystals, 13, 2023
8HSK	Insulin single mutant INS-Q Descriptor: Insulin A chain, Insulin B chain, SULFATE ION Authors: Rao, S.S, Kundapura, S.V, Kulal, A, Ramagopal, U.A. Deposit date: 2022-12-19 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Insulin single mutant INS-Q To Be Published
3I40	Human insulin Descriptor: Insulin A chain, Insulin B chain Authors: Timofeev, V.I, Bezuglov, V.V, Miroshnikov, K.A, Chuprov-Netochin, R.N, Kuranova, I.P. Deposit date: 2009-07-01 Release date: 2010-01-05 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.85 Å) Cite: X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid. Acta Crystallogr.,Sect.F, 66, 2010
8HSF	Insulin triple mutant INS-RQD Descriptor: Insulin A chain, Insulin B chain Authors: Kundapura, S.V, Rao, S.S, Kulal, A, Ramagopal, U.A. Deposit date: 2022-12-19 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Insulin triple mutant INS-RQD To Be Published
3I3Z	Human insulin Descriptor: Insulin A chain, Insulin B chain Authors: Timofeev, V.I, Bezuglov, V.V, Miroshnikov, K.A, Cuprov-Netochin, R.N, Samigina, V.R, Kuranova, I.P. Deposit date: 2009-07-01 Release date: 2010-01-05 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid. Acta Crystallogr.,Sect.F, 66, 2010
5MIZ	MD ensemble of bovine insulin Descriptor: Insulin Authors: Efimov, S.V, Zgadzay, Y.O, Klochkov, V.V. Deposit date: 2016-11-29 Release date: 2017-01-25 Last modified: 2019-05-08 Method: SOLUTION NMR Cite: MD ensemble of bovine insulin To Be Published
5MHD	Biosynthetic engineered A22S-B3K-B31R human insulin monomer structure in water/acetonitrile solutions. Descriptor: Insulin Authors: Bocian, W, Kozerski, L, Bednarek, E, Sitkowski, J. Deposit date: 2016-11-24 Release date: 2017-08-09 Last modified: 2019-05-08 Method: SOLUTION NMR Cite: Structure and pharmaceutical formulation development of a new long-acting recombinant human insulin analog studied by NMR and MS. J Pharm Biomed Anal, 135, 2017
3INC	Crystal structure of human insulin with Ni+2 complex Descriptor: Insulin A chain, Insulin B chain, NICKEL (II) ION Authors: Raghavendra, N, Pattabhi, V, Rajan, S.S. Deposit date: 2009-08-12 Release date: 2010-08-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin To be Published
3IR0	Crystal Structure of Human Insulin complexed with Cu+2 metal ion Descriptor: COPPER (II) ION, Insulin A chain, Insulin B chain Authors: Raghavendra, N, Pattabhi, V, Rajan, S.S. Deposit date: 2009-08-21 Release date: 2010-09-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Metal induced structural changes observed in Human insulin To be Published
3INS	STRUCTURE OF INSULIN. RESULTS OF JOINT NEUTRON AND X-RAY REFINEMENT Descriptor: INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION Authors: Wlodawer, A, Savage, H. Deposit date: 1988-10-14 Release date: 1989-01-09 Last modified: 2017-11-29 Method: NEUTRON DIFFRACTION (1.5 Å), X-RAY DIFFRACTION Cite: Structure of insulin: results of joint neutron and X-ray refinement. Acta Crystallogr.,Sect.B, 45, 1989
3ILG	Crystal structure of humnan insulin Sr+2 complex Descriptor: Insulin A chain, Insulin B chain, STRONTIUM ION Authors: Raghavendra, N, Pattabhi, V, Rajan, S.S. Deposit date: 2009-08-07 Release date: 2010-08-11 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin To be Published
5MAM	Human insulin in complex with serotonin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. Deposit date: 2016-11-03 Release date: 2017-04-05 Last modified: 2017-05-31 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
5MWQ	Biosynthetic engineered A21K-B31K-B32R human insulin monomer structure in water/acetonitrile solution Descriptor: Insulin Authors: Bocian, W, Kozerski, L. Deposit date: 2017-01-19 Release date: 2018-02-14 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Lysine mis-incorporation at asparagine position during recombinant proteins production in E. coli To Be Published
5MT9	Human insulin in complex with serotonin and arginine Descriptor: ARGININE, CHLORIDE ION, Insulin, ... Authors: Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. Deposit date: 2017-01-07 Release date: 2017-04-05 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
5MT3	Human insulin in complex with serotonin and arginine Descriptor: ARGININE, CHLORIDE ION, Insulin, ... Authors: Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. Deposit date: 2017-01-06 Release date: 2017-04-05 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
8IPZ	Crystal structure of insulin detemir Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: DeMirci, H, Ayan, E. Deposit date: 2023-03-15 Release date: 2023-12-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal structure of insulin detemir To Be Published

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