130L
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STRUCTURES OF RANDOMLY GENERATED MUTANTS OF T4 LYSOZYME SHOW THAT PROTEIN STABILITY CAN BE ENHANCED BY RELAXATION OF STRAIN AND BY IMPROVED HYDROGEN BONDING VIA BOUND SOLVENT
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Pjura, P., Matthews, B.W.
Deposit date:1993-05-28
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced by relaxation of strain and by improved hydrogen bonding via bound solvent.
Protein Sci., 2, 1993
131D
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THE LOW-TEMPERATURE CRYSTAL STRUCTURE OF THE PURE-SPERMINE FORM OF Z-DNA REVEALS BINDING OF A SPERMINE MOLECULE IN THE MINOR GROOVE
Descriptor:DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SPERMINE, SODIUM ION
Authors:Bancroft, D., Williams, L.D., Rich, A., Egli, M.
Deposit date:1993-06-18
Release date:1993-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:The low-temperature crystal structure of the pure-spermine form of Z-DNA reveals binding of a spermine molecule in the minor groove.
Biochemistry, 33, 1994
131L
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STRUCTURES OF RANDOMLY GENERATED MUTANTS OF T4 LYSOZYME SHOW THAT PROTEIN STABILITY CAN BE ENHANCED BY RELAXATION OF STRAIN AND BY IMPROVED HYDROGEN BONDING VIA BOUND SOLVENT
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Pjura, P., Matthews, B.W.
Deposit date:1993-05-28
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced by relaxation of strain and by improved hydrogen bonding via bound solvent.
Protein Sci., 2, 1993
132D
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SOLUTION STRUCTURE OF THE TN AN DNA DUPLEX GCCGTTAACGGC CONTAINING THE HPA I RESTRICTION SITE
Descriptor:DNA (5'-D(P*GP*CP*CP*GP*TP*TP*AP*AP*CP*GP*GP*C)-3')
Authors:Kim, S.-G., Reid, B.R.
Deposit date:1993-06-24
Release date:1994-01-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the TnAn DNA duplex GCCGTTAACGCG containing the HpaI restriction site.
Biochemistry, 31, 1992
132L
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STRUCTURAL CONSEQUENCES OF REDUCTIVE METHYLATION OF LYSINE RESIDUES IN HEN EGG WHITE LYSOZYME: AN X-RAY ANALYSIS AT 1.8 ANGSTROMS RESOLUTION
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Rayment, I., Rypniewski, W.R., Holden, H.M.
Deposit date:1993-06-02
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural consequences of reductive methylation of lysine residues in hen egg white lysozyme: an X-ray analysis at 1.8-A resolution.
Biochemistry, 32, 1993
133D
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THE CRYSTAL STRUCTURE OF N4-METHYLCYTOSINE.GUANOSIN BASE-PAIRS IN THE SYNTHETIC HEXANUCLEOTIDE D(CGCGM(4)CG)
Descriptor:DNA (5'-D(*CP*GP*CP*GP*(C34)P*G)-3')
Authors:Cervi, A.R., Guy, A., Leonard, G.A., Teoule, R., Hunter, W.N.
Deposit date:1993-07-29
Release date:1994-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of N4-methylcytosine.guanosine base-pairs in the synthetic hexanucleotide d(CGCGm4CG).
Nucleic Acids Res., 21, 1993
133L
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ROLE OF ARG 115 IN THE CATALYTIC ACTION OF HUMAN LYSOZYME. X-RAY STRUCTURE OF HIS 115 AND GLU 115 MUTANTS
Descriptor:HUMAN LYSOZYME
Authors:Harata, K., Muraki, M., Jigami, Y.
Deposit date:1993-06-01
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Role of Arg115 in the catalytic action of human lysozyme. X-ray structure of His115 and Glu115 mutants.
J.Mol.Biol., 233, 1993
134D
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SOLUTION STRUCTURE OF A PURINE(DOT)PURINE(DOT)PYRIMIDINE DNA TRIPLEX CONTAINING G(DOT)GC AND T(DOT)AT TRIPLES
Descriptor:DNA TRIPLEX
Authors:Patel, D.J., Radhakrishnan, I.
Deposit date:1993-08-30
Release date:1994-04-30
Last modified:2015-04-15
Method:SOLUTION NMR
Cite:Solution structure of a purine.purine.pyrimidine DNA triplex containing G.GC and T.AT triples.
Structure, 1, 1993
134L
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ROLE OF ARG 115 IN THE CATALYTIC ACTION OF HUMAN LYSOZYME. X-RAY STRUCTURE OF HIS 115 AND GLU 115 MUTANTS
Descriptor:HUMAN LYSOZYME
Authors:Harata, K., Muraki, M., Jigami, Y.
Deposit date:1993-06-01
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Role of Arg115 in the catalytic action of human lysozyme. X-ray structure of His115 and Glu115 mutants.
J.Mol.Biol., 233, 1993
135D
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SOLUTION STRUCTURE OF A PURINE(DOT)PURINE(DOT)PYRIMIDINE DNA TRIPLEX CONTAINING G(DOT)GC AND T(DOT)AT TRIPLES
Descriptor:DNA TRIPLEX
Authors:Radhakrishnan, I., Patel, D.J.
Deposit date:1993-08-30
Release date:1994-04-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a purine.purine.pyrimidine DNA triplex containing G.GC and T.AT triples.
Structure, 1, 1993
135L
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X-RAY STRUCTURE OF MONOCLINIC TURKEY EGG LYSOZYME AT 1.3 ANGSTROMS RESOLUTION
Descriptor:TURKEY EGG WHITE LYSOZYME
Authors:Harata, K.
Deposit date:1993-06-10
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:X-ray structure of monoclinic turkey egg lysozyme at 1.3 A resolution.
Acta Crystallogr.,Sect.D, 49, 1993
136D
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SOLUTION STRUCTURE OF A PURINE(DOT)PURINE(DOT)PYRIMIDINE DNA TRIPLEX CONTAINING G(DOT)GC AND T(DOT)AT TRIPLES
Descriptor:DNA TRIPLEX
Authors:Radhakrishnan, I., Patel, D.J.
Deposit date:1993-08-30
Release date:1994-04-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a purine.purine.pyrimidine DNA triplex containing G.GC and T.AT triples.
Structure, 1, 1993
137D
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A-DNA DECAMER D(GCGGGCCCGC)-ORTHORHOMBIC CRYSTAL FORM
Descriptor:DNA (5'-D(*GP*CP*GP*GP*GP*CP*CP*CP*GP*C)-3')
Authors:Ramakrishnan, B., Sundaralingam, M.
Deposit date:1993-09-15
Release date:1994-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Evidence for crystal environment dominating base sequence effects on DNA conformation: crystal structures of the orthorhombic and hexagonal polymorphs of the A-DNA decamer d(GCGGGCCCGC) and comparison with their isomorphous crystal structures.
Biochemistry, 32, 1993
137L
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STRUCTURAL BASIS OF AMINO ACID ALPHA HELIX PROPENSITY
Descriptor:T4 LYSOZYME
Authors:Blaber, M., Matthews, B.W.
Deposit date:1993-08-17
Release date:1994-07-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of amino acid alpha helix propensity.
Science, 260, 1993
138D
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A-DNA DECAMER D(GCGGGCCCGC)-HEXAGONAL CRYSTAL FORM
Descriptor:DNA (5'-D(*GP*CP*GP*GP*GP*CP*CP*CP*GP*C)-3')
Authors:Ramakrishnan, B., Sundaralingam, M.
Deposit date:1993-09-15
Release date:1994-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Evidence for crystal environment dominating base sequence effects on DNA conformation: crystal structures of the orthorhombic and hexagonal polymorphs of the A-DNA decamer d(GCGGGCCCGC) and comparison with their isomorphous crystal structures.
Biochemistry, 32, 1993
138L
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RAPID CRYSTALLIZATION OF T4 LYSOZYME BY INTERMOLECULAR DISULFIDE CROSSLINKING
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Heinz, D.W., Matthews, B.W.
Deposit date:1993-09-01
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rapid crystallization of T4 lysozyme by intermolecular disulfide cross-linking.
Protein Eng., 7, 1994
139D
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SOLUTION STRUCTURE OF A PARALLEL-STRANDED G-QUADRUPLEX DNA
Descriptor:DNA (5'-D(*TP*TP*GP*GP*GP*GP*T)-3')
Authors:Patel, D.J., Wang, Y.
Deposit date:1993-09-28
Release date:1994-01-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a parallel-stranded G-quadruplex DNA.
J.Mol.Biol., 234, 1993
139L
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RAPID CRYSTALLIZATION OF T4 LYSOZYME BY INTERMOLECULAR DISULFIDE CROSSLINKING
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Heinz, D.W., Matthews, B.W.
Deposit date:1993-09-01
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rapid crystallization of T4 lysozyme by intermolecular disulfide cross-linking.
Protein Eng., 7, 1994
13GS
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GLUTATHIONE S-TRANSFERASE COMPLEXED WITH SULFASALAZINE
Descriptor:GLUTATHIONE S-TRANSFERASE, GLUTATHIONE, 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID, ...
Authors:Oakley, A.J., Lo Bello, M., Parker, M.W.
Deposit date:1997-11-20
Release date:1999-01-13
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Ligandin (Non-Substrate) Binding Site of Human Pi Class Glutathione Transferase is Located in the Electrophile Binding Site (H-Site).
J.Mol.Biol., 291, 1999
13PK
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TERNARY COMPLEX OF PHOSPHOGLYCERATE KINASE FROM TRYPANOSOMA BRUCEI
Descriptor:3-PHOSPHOGLYCERATE KINASE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Bernstein, B.E., Michels, P.A.M., Hol, W.G.J.
Deposit date:1996-11-23
Release date:1997-12-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Synergistic effects of substrate-induced conformational changes in phosphoglycerate kinase activation.
Nature, 385, 1997
140D
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SOLUTION STRUCTURE OF A CONSERVED DNA SEQUENCE FROM THE HIV-1 GENOME: RESTRAINED MOLECULAR DYNAMICS SIMULATION WITH DISTANCE AND TORSION ANGLE RESTRAINTS DERIVED FROM TWO-DIMENSIONAL NMR SPECTRA
Descriptor:DNA (5'-D(*AP*GP*CP*TP*TP*GP*CP*CP*TP*TP*GP*AP*G)-3'), DNA (5'-D(*CP*TP*CP*AP*AP*GP*GP*CP*AP*AP*GP*CP*T)-3')
Authors:Mujeeb, A., Kerwin, S.M., Kenyon, G.L., James, T.L.
Deposit date:1993-09-24
Release date:1994-04-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a conserved DNA sequence from the HIV-1 genome: restrained molecular dynamics simulation with distance and torsion angle restraints derived from two-dimensional NMR spectra.
Biochemistry, 32, 1993
140L
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ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Baldwin, E., Matthews, B.W.
Deposit date:1993-10-15
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme.
Science, 262, 1993
141D
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SOLUTION STRUCTURE OF A CONSERVED DNA SEQUENCE FROM THE HIV-1 GENOME: RESTRAINED MOLECULAR DYNAMICS SIMULATION WITH DISTANCE AND TORSION ANGLE RESTRAINTS DERIVED FROM TWO-DIMENSIONAL NMR SPECTRA
Descriptor:DNA (5'-D(*AP*GP*CP*TP*TP*GP*CP*CP*TP*TP*GP*AP*G)-3'), DNA (5'-D(*CP*TP*CP*AP*AP*GP*GP*CP*AP*AP*GP*CP*T)-3')
Authors:Mujeeb, A., James, T.L.
Deposit date:1993-09-24
Release date:1994-04-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a conserved DNA sequence from the HIV-1 genome: restrained molecular dynamics simulation with distance and torsion angle restraints derived from two-dimensional NMR spectra.
Biochemistry, 32, 1993
141L
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ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Baldwin, E., Matthews, B.W.
Deposit date:1993-10-15
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme.
Science, 262, 1993
142D
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SOLUTION STRUCTURE OF A CONSERVED DNA SEQUENCE FROM THE HIV-1 GENOME: RESTRAINED MOLECULAR DYNAMICS SIMULATION WITH DISTANCE AND TORSION ANGLE RESTRAINTS DERIVED FROM TWO-DIMENSIONAL NMR SPECTRA
Descriptor:DNA (5'-D(*AP*GP*CP*TP*TP*GP*CP*CP*TP*TP*GP*AP*G)-3'), DNA (5'-D(*CP*TP*CP*AP*AP*GP*GP*CP*AP*AP*GP*CP*T)-3')
Authors:Mujeeb, A., James, T.L.
Deposit date:1993-09-24
Release date:1994-04-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a conserved DNA sequence from the HIV-1 genome: restrained molecular dynamics simulation with distance and torsion angle restraints derived from two-dimensional NMR spectra.
Biochemistry, 32, 1993