Mine: New entries

6LF3
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3D DOMAIN-SWAPPED DIMER OF THE MALTOSE-BINDING PROTEIN FUSED TO A FRAGMENT OF THE PROTEIN-TYROSINE KINASE 2-BETA
Descriptor:Maltose/maltodextrin-binding periplasmic protein,Protein-tyrosine kinase 2-beta, MALTOSE
Authors:Momin, A.A., Shahul Hameed, U.F., Arold, S.T.
Deposit date:2019-11-28
Release date:2019-12-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Passenger sequences can promote interlaced dimers in a common variant of the maltose-binding protein
To be published
6N9J
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X-RAY STRUCTURE OF A SECRETED C11 CYSTEINE PROTEASE FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH AN IRREVERSIBLE PEPTIDE INHIBITOR
Descriptor:Clostripain-related protein, Covalently bound peptide inhibitor
Authors:Wolan, D.W., Gonzalez-Paez, G.E., Roncase, E.J.
Deposit date:2018-12-03
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:X-ray structure of a secreted C11 cysteine protease from Bacteroides thetaiotaomicron in complex with an irreversible peptide inhibitor
To Be Published
6NA3
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CRYSTAL STRUCTURE OF APO-FORM OF ECR
Descriptor:Putative crotonyl-CoA reductase, Pyrrolidine, CHLORIDE ION
Authors:DeMirci, H.
Deposit date:2018-12-05
Release date:2019-12-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Coupled intersubunit dynamics enable fast CO2 fixation by reductive carboxylases
To Be Published
6NA5
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CRYSTAL STRUCTURE OF ECR IN COMPLEX WITH NADP+
Descriptor:Putative crotonyl-CoA reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:DeMirci, H.
Deposit date:2018-12-05
Release date:2019-12-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Coupled intersubunit dynamics enable fast CO2 fixation by reductive carboxylases
To Be Published
6NA6
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SERIAL FEMTOSECOND X-RAY CRYSTALLOGRAPHY STRUCTURE OF ECR IN COMPLEX WITH NADPH
Descriptor:Putative crotonyl-CoA reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:DeMirci, H.
Deposit date:2018-12-05
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Coupled intersubunit dynamics enable fast CO2 fixation by reductive carboxylases
To Be Published
6NAC
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CRYSTAL STRUCTURE OF [FEFE]-HYDROGENASE I (CPI) SOLVED WITH SINGLE PULSE FREE ELECTRON LASER DATA
Descriptor:Iron hydrogenase 1, dicarbonyl[bis(cyanide-kappaC)]-mu-(iminodimethanethiolatato-1kappaS:2kappaS)-mu-(oxomethylidene)diiron(2+), IRON/SULFUR CLUSTER, ...
Authors:Cohen, A.E., Davidson, C.M., Zadvornyy, O.A., Keable, S.M., Lyubimov, A.Y., Song, J., McPhillips, S.E., Soltis, S.M., Peters, J.W.
Deposit date:2018-12-05
Release date:2019-12-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Tuning catalytic bias of hydrogen gas producing hydrogenases
To Be Published
6NAE
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CRYSTAL STRUCTURE OF EBOLA ZAIRE GP PROTEIN WITH BOUND ARN0074898
Descriptor:Envelope glycoprotein,Envelope glycoprotein,Envelope glycoprotein, Envelope glycoprotein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-05
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of Ebola zaire GP protein with bound ARN0074898
to be published
6NAG
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X-RAY STRUCTURE OF A SECRETED C11 CYSTEINE PROTEASE FROM BACTEROIDES THETAIOTAOMICRON "IOTAPAIN
Descriptor:Clostripain-related protein, PROLINE
Authors:Wolan, D.W., Gonzalez-Paez, G.E., Roncase, E.J.
Deposit date:2018-12-05
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.683 Å)
Cite:X-ray structure of a secreted C11 cysteine protease from Bacteroides thetaiotaomicron "iotapain"
To Be Published
6NAJ
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INTEGRIN ALPHAVBETA3 ECTODOMAIN BOUND TO HR10 VARIANT OF THE 10TH DOMAIN OF FIBRONECTIN.
Descriptor:Integrin alpha-V, Integrin beta-3, Fibronectin, ...
Authors:van Agthoven, J.F., Armaout, M.A.
Deposit date:2018-12-05
Release date:2019-12-11
Method:X-RAY DIFFRACTION (3.104 Å)
Cite:Integrin AlphaVBeta3 ectodomain bound to Hr10 variant of the 10th domain of Fibronectin.
To Be Published
6NIL
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CRYOEM STRUCTURE OF THE TRUNCATED HIV-1 VIF/CBFBETA/A3F COMPLEX
Descriptor:DNA dC->dU-editing enzyme APOBEC-3F, Core-binding factor subunit beta, Virion infectivity factor, ...
Authors:Hu, Y., Xiong, Y.
Deposit date:2018-12-29
Release date:2019-12-11
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of antagonism of human APOBEC3F by HIV-1 Vif
Nat.Struct.Mol.Biol., 2019
6NUJ
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HIV-1 INTEGRASE CATALYTIC CORE DOMAIN COMPLEXED WITH ALLOSTERIC INHIBITOR BI-224436
Descriptor:Integrase, (2S)-tert-butoxy[4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl]acetic acid
Authors:Lindenberger, J.J., Kvaratskhelia, M.
Deposit date:2019-02-01
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.100027 Å)
Cite:HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors.
Elife, 8, 2019
6NVT
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CRYSTAL STRUCTURE OF TLA-1 EXTENDED SPECTRUM BETA-LACTAMASE
Descriptor:Beta-lactamase, SULFATE ION, CHLORIDE ION, ...
Authors:Rudino-Pinera, E., Cifuentes-Castro, V.H., Rodriguez-Almazan, C.
Deposit date:2019-02-05
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of ESBL TLA-1 in complex with clavulanic acid reveals a second acylation site.
Biochem.Biophys.Res.Commun., 2019
6NVU
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CRYSTAL STRUCTURE OF TLA-1 EXTENDED SPECTRUM BETA-LACTAMASE IN COMPLEX WITH CLAVULANIC ACID
Descriptor:Beta-lactamase, SULFATE ION, ACETATE ION, ...
Authors:Rudino-Pinera, E., Cifuentes-Castro, V.H., Rodriguez-Almazan, C.
Deposit date:2019-02-05
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of ESBL TLA-1 in complex with clavulanic acid reveals a second acylation site.
Biochem.Biophys.Res.Commun., 2019
6O9R
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THE CAPSID STRUCTURE OF EMPTY AAVRH.10 PARTICLES
Descriptor:Capsid protein VP1
Authors:Mietzsch, M., Agbandje-McKenna, M.
Deposit date:2019-03-14
Release date:2019-12-11
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Comparative Analysis of the Capsid Structures of AAVrh.10 and AAVrh.39
J.Virol., 2019
6OCO
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HUMAN PI3KDELTA IN COMPLEX WITH COMPOUND 6
Descriptor:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 3-kinase regulatory subunit alpha, 4-[(1S,4S)-5-(3-chlorophenyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]-2-(pyridin-3-yl)pyrimidine-5-carbonitrile
Authors:Lesburg, C.A., Augustin, M.A.
Deposit date:2019-03-25
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Discovery and optimization of heteroaryl piperazines as potent and selective PI3K delta inhibitors.
Bioorg.Med.Chem.Lett., 2019
6OCU
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HUMAN PI3KDELTA IN COMPLEX WITH COMPOUND 29
Descriptor:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 3-kinase regulatory subunit alpha, 5-{(3R)-3-methyl-4-[(1R,2R)-2-methylcyclopropane-1-carbonyl]piperazin-1-yl}-3-(1-methyl-1H-pyrazol-4-yl)pyrazine-2-carbonitrile
Authors:Lesburg, C.A., Augustin, M.A.
Deposit date:2019-03-25
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Discovery and optimization of heteroaryl piperazines as potent and selective PI3K delta inhibitors.
Bioorg.Med.Chem.Lett., 2019
6OL9
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STRUCTURE OF THE M5 MUSCARINIC ACETYLCHOLINE RECEPTOR (M5-T4L) BOUND TO TIOTROPIUM
Descriptor:Muscarinic acetylcholine receptor M5, T4 Lysozyme fusion, OLEIC ACID, ...
Authors:Vuckovic, Z., Christopoulos, A., Thal, D.M.
Deposit date:2019-04-16
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.541 Å)
Cite:Crystal structure of the M5muscarinic acetylcholine receptor.
Proc.Natl.Acad.Sci.USA, 2019
6OLY
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FULL-LENGTH MTHK CHANNEL AT 3.1 ANGSTROM RESOLUTION
Descriptor:Calcium-gated potassium channel MthK, CALCIUM ION
Authors:Rothberg, B.S.
Deposit date:2019-04-17
Release date:2019-12-11
Method:X-RAY DIFFRACTION (3.112 Å)
Cite:Molecular mechanism of a potassium channel gating through activation gate-selectivity filter coupling.
Nat Commun, 10, 2019
6OM1
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CRYSTAL STRUCTURE OF AN ATYPICAL INTEGRIN
Descriptor:Integrin alpha-V, Integrin beta-8, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wang, J.C., Springer, T.A.
Deposit date:2019-04-17
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Crystal structure of atypical integrin alphaV beta8
Nat Commun, 2019
6OM2
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CRYSTAL STRUCTURE OF ATYPICAL INTEGRIN ALPHAV BETA8 WITH PROTGF-BETA1 LIGAND PEPTIDE
Descriptor:Integrin alpha-V, Integrin beta-8, proTGF-beta1 RGD peptide, ...
Authors:Wang, J.C., Springer, T.A.
Deposit date:2019-04-17
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Crystal structure of atypical integrin alphaV beta8
Nat Commun, 2019
6OQZ
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CRYSTAL STRUCTURE OF GLUCOSE ISOMERASE FROM NON-MEROHEDRALLY TWINNED CRYSTALS
Descriptor:Xylose isomerase, MANGANESE (II) ION, MAGNESIUM ION, ...
Authors:Sevvana, M., Ruf, M., Uson, I., Sheldrick, G.M., Herbst-Irmer, R.
Deposit date:2019-04-29
Release date:2019-12-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Non-merohedral twinning: from minerals to proteins.
Acta Crystallogr D Struct Biol, 75, 2019
6OR0
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CRYSTAL STRUCTURE OF INSULIN FROM NON-MEROHEDRALLY TWINNED CRYSTALS
Descriptor:Insulin chain A, Insulin chain B
Authors:Sevvana, M., Ruf, M., Uson, I., Sheldrick, G.M., Herbst-Irmer, R.
Deposit date:2019-04-29
Release date:2019-12-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Non-merohedral twinning: from minerals to proteins.
Acta Crystallogr D Struct Biol, 75, 2019
6OZU
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CRYSTAL STRUCTURE OF THE MIF4G DOMAIN OF TRYPANOSOMA CRUZI TRANSLATION INITIATION FACTOR EIF4G5
Descriptor:Eukaryotic translation initiation factor 4 gamma 5, SULFATE ION, GLYCEROL
Authors:Guimaraes, B.G., Santos, L.P.C.
Deposit date:2019-05-16
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the MIF4G domain of the Trypanosoma cruzi translation initiation factor EIF4G5
Acta Crystallogr.,Sect.F, 75, 2019
6P09
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HUMAN DNA LIGASE 1 BOUND TO AN ADENYLATED, DIDEOXY TERMINATED DNA NICK WITH 200 MM MG2+
Descriptor:DNA ligase 1, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3'), ...
Authors:Schellenberg, M.J., Williams, R.S., Tumbale, P.S., Riccio, A.A.
Deposit date:2019-05-16
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6P0A
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HUMAN DNA LIGASE 1 BOUND TO AN ADENYLATED, DIDEOXY TERMINATED DNA NICK WITH 2 MM MG2+
Descriptor:DNA ligase 1, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3'), ...
Authors:Schellenberg, M.J., Williams, R.S., Tumbale, P.S., Riccio, A.A.
Deposit date:2019-05-16
Release date:2019-12-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019