PDB: 91 resultsInfo pagesStatus searchChemie searchBIRD

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6MYX	EM structure of Bacillus subtilis ribonucleotide reductase inhibited double-helical filament of NrdE alpha subunit with dATP Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Ribonucleoside-diphosphate reductase Authors: Thomas, W.C, Bacik, J.P, Chen, J.Z, Ando, N. Deposit date: 2018-11-02 Release date: 2019-06-19 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (6 Å) Cite: Convergent allostery in ribonucleotide reductase. Nat Commun, 10, 2019
1XJE	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dTTP-GDP complex Descriptor: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-10-11 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
1XJM	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dTTP complex Descriptor: MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE, ribonucleotide reductase, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
1XJK	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP-ADP complex Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-11-22 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
1XJF	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP complex Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ribonucleotide reductase, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
1XJG	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP-UDP complex Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2004
1XJJ	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP complex Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ribonucleotide reductase, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2005
1XJN	Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP-CDP complex Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, ... Authors: Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. Deposit date: 2004-09-23 Release date: 2005-12-06 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2004
1ZYZ	Structures of Yeast Ribonucloetide Reductase I Descriptor: GLYCINE, Ribonucleoside-diphosphate reductase large chain 1 Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-13 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
3O0N	Thermotoga maritima Ribonucleotide Reductase, NrdJ, in complex with dTTP and Adenosylcobalamin Descriptor: 5'-DEOXYADENOSINE, CHLORIDE ION, COBALAMIN, ... Authors: Larsson, K.-M, Logan, D.T, Nordlund, P. Deposit date: 2010-07-19 Release date: 2010-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural Basis for Adenosylcobalamin Activation in AdoCbl-Dependent Ribonucleotide Reductases. Acs Chem.Biol., 5, 2010
3O0Q	Thermotoga maritima Ribonucleotide Reductase, NrdJ, in complex with dTTP, GDP and Adenosine Descriptor: ADENOSINE, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Larsson, K.-M, Logan, D.T, Nordlund, P. Deposit date: 2010-07-19 Release date: 2010-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Basis for Adenosylcobalamin Activation in AdoCbl-Dependent Ribonucleotide Reductases. Acs Chem.Biol., 5, 2010
3O0O	Thermotoga maritima Ribonucleotide Reductase, NrdJ, in complex with dTTP, GDP and Adenosylcobalamin Descriptor: 5'-DEOXYADENOSINE, COBALAMIN, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Larsson, K.-M, Logan, D.T, Nordlund, P. Deposit date: 2010-07-19 Release date: 2010-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Basis for Adenosylcobalamin Activation in AdoCbl-Dependent Ribonucleotide Reductases. Acs Chem.Biol., 5, 2010
3PAW	Low resolution X-ray crystal structure of Yeast Rnr1p with dATP bound in the A-site Descriptor: Ribonucleoside-diphosphate reductase large chain 1 Authors: Fairman, J.W, Wijerathna, S.R, Dealwis, C.G. Deposit date: 2010-10-19 Release date: 2011-02-23 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (6.61 Å) Cite: Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization. Nat.Struct.Mol.Biol., 18, 2011
3R1R	RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH AMPPNP OCCUPYING THE ACTIVITY SITE FROM ESCHERICHIA COLI Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN Authors: Eriksson, M, Eklund, H. Deposit date: 1997-07-21 Release date: 1998-01-28 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding. Structure, 5, 1997
3RSR	Crystal Structure of 5-NITP Inhibition of Yeast Ribonucleotide Reductase Descriptor: 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO-1H-INDOLE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1 Authors: Wan, Q, Mohammed, F, Jha, S, Motea, E, Berdis, A, Dealwis, C.G. Deposit date: 2011-05-02 Release date: 2012-11-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase. Mol.Cancer Ther., 11, 2012
3S8B	Structure of Yeast Ribonucleotide Reductase 1 with AMPPNP and CDP Descriptor: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. Deposit date: 2011-05-27 Release date: 2012-04-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
3S8A	Structure of Yeast Ribonucleotide Reductase R293A with dGTP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1 Authors: Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. Deposit date: 2011-05-27 Release date: 2012-04-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
3S87	Structure of Yeast Ribonucleotide Reductase 1 with dGTP and ADP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. Deposit date: 2011-05-27 Release date: 2012-04-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
1ZZD	Structures of Yeast Ribonucleotide Reductase I Descriptor: Ribonucleoside-diphosphate reductase large chain 1, Ribonucleoside-diphosphate reductase small chain 2 Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-13 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2BQ1	Ribonucleotide reductase class 1b holocomplex R1E,R2F from Salmonella typhimurium Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, FE (III) ION, MAGNESIUM ION, ... Authors: Uppsten, M, Farnegardh, M, Domkin, V, Uhlin, U. Deposit date: 2005-04-26 Release date: 2006-05-17 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.99 Å) Cite: The First Holocomplex Structure of Ribonucleotide Reductase Gives New Insight Into its Mechanism of Action J.Mol.Biol., 359, 2006
2CVU	Structures of Yeast Ribonucleotide Reductase I Descriptor: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVS	Structures of Yeast Ribonucleotide Reductase I Descriptor: Ribonucleoside-diphosphate reductase large chain 1 Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVX	Structures of Yeast Ribonucleotide Reductase I Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVT	Structures of Yeast Ribonucleotide Reductase I Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonucleoside-diphosphate reductase large chain 1 Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVV	Structures of Yeast Ribonucleotide Reductase I Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonucleoside-diphosphate reductase large chain 1, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006

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