PDB: 59 resultsInfo pagesStatus searchChemie searchBIRD

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3ZCB	VbhT Fic protein from Bartonella schoenbuchensis in complex with VbhA antitoxin mutant E24G and ATP Descriptor: ADENOSINE MONOPHOSPHATE-PROTEIN TRANSFERASE VBHT, ADENOSINE-5'-TRIPHOSPHATE, ANTITOXIN VBHA, ... Authors: Goepfert, A, Schirmer, T. Deposit date: 2012-11-19 Release date: 2013-06-19 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Conserved Inhibitory Mechanism and Competent ATP Binding Mode for Adenylyltransferases with Fic Fold. Plos One, 8, 2013
3ZEC	Fic protein from SHEWANELLA ONEIDENSIS (E73G mutant) in complex with AMPPNP Descriptor: ADENOSINE MONOPHOSPHATE-PROTEIN TRANSFERASE SOFIC, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Goepfert, A, Schirmer, T. Deposit date: 2012-12-04 Release date: 2013-06-19 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Conserved Inhibitory Mechanism and Competent ATP Binding Mode for Adenylyltransferases with Fic Fold. Plos One, 8, 2013
6SIU	Crystal structure of IbpAFic2 covalently tethered to Cdc42 Descriptor: Cell division control protein 42 homolog, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Gulen, B, Roselin, M, Albers, M, Hedberg, C, Itzen, A, Pogenberg, V. Deposit date: 2019-08-12 Release date: 2020-03-18 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture. Nat.Chem., 12, 2020
6ZMD	Crystal structure of HYPE covalently tethered to BiP bound to AMP-PNP Descriptor: Endoplasmic reticulum chaperone BiP, MAGNESIUM ION, PHOSPHATE ION, ... Authors: Fauser, J, Gulen, B, Pett, C, Hedberg, C, Itzen, A, Pogenberg, V. Deposit date: 2020-07-02 Release date: 2021-04-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.64 Å) Cite: Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD. Nat Commun, 12, 2021
4ITR	Crystal Structure of IbpAFic2-H3717A in complex with adenylylated Cdc42 Descriptor: ADENOSINE MONOPHOSPHATE, Adenosine monophosphate-protein transferase and cysteine protease IbpA, Cell division control protein 42 homolog, ... Authors: Xiao, J, Dixon, J.E. Deposit date: 2013-01-18 Release date: 2013-02-20 Last modified: 2023-06-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis of Fic-mediated adenylylation. Nat.Struct.Mol.Biol., 17, 2010
7B80	DeAMPylation complex of monomeric FICD and AMPylated BiP (state 2) Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... Authors: Perera, L.A, Ron, D. Deposit date: 2020-12-12 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD. Nat Commun, 12, 2021
7B7Z	DeAMPylation complex of monomeric FICD and AMPylated BiP (state 1) Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE MONOPHOSPHATE, Endoplasmic reticulum chaperone BiP, ... Authors: Perera, L.A, Ron, D. Deposit date: 2020-12-12 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD. Nat Commun, 12, 2021
3K33	Crystal structure of the Phd-Doc complex Descriptor: ACETATE ION, Death on curing protein, Polypeptide of unknown amino acids and source, ... Authors: Loris, R, Garcia-Pino, A. Deposit date: 2009-10-01 Release date: 2010-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity. Cell(Cambridge,Mass.), 142, 2010
3KH2	Crystal structure of the P1 bacteriophage Doc toxin (F68S) in complex with the Phd antitoxin (L17M/V39A). Northeast Structural Genomics targets ER385-ER386 Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Death on curing protein, ... Authors: Arbing, M.A, Kuzin, A.P, Su, M, Abashidze, M, Verdon, G, Liu, M, Xiao, R, Acton, T, Inouye, M, Montelione, G.T, Woychik, N.A, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) Deposit date: 2009-10-29 Release date: 2010-08-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems. Structure, 18, 2010

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