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4EKR
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BU of 4ekr by Molmil
T4 Lysozyme L99A/M102H with 2-Cyanophenol Bound
Descriptor: 2-HYDROXYETHYL DISULFIDE, 2-hydroxybenzonitrile, ACETATE ION, ...
Authors:Merski, M, Shoichet, B.K.
Deposit date:2012-04-09
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Engineering a model protein cavity to catalyze the Kemp elimination.
Proc.Natl.Acad.Sci.USA, 109, 2012
261L
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BU of 261l by Molmil
STRUCTURAL CHARACTERISATION OF AN ENGINEERED TANDEM REPEAT CONTRASTS THE IMPORTANCE OF CONTEXT AND SEQUENCE IN PROTEIN FOLDING
Descriptor: LYSOZYME
Authors:Sagermann, M, Baase, W.A, Matthews, B.W.
Deposit date:1999-05-11
Release date:1999-05-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural characterization of an engineered tandem repeat contrasts the importance of context and sequence in protein folding.
Proc.Natl.Acad.Sci.USA, 96, 1999
220L
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BU of 220l by Molmil
GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS
Descriptor: BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W.
Deposit date:1997-06-25
Release date:1998-03-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions.
J.Mol.Biol., 277, 1998
225L
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BU of 225l by Molmil
GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS
Descriptor: BETA-MERCAPTOETHANOL, PARA-XYLENE, T4 LYSOZYME
Authors:Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W.
Deposit date:1997-06-25
Release date:1998-03-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions.
J.Mol.Biol., 277, 1998
232L
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BU of 232l by Molmil
T4 LYSOZYME MUTANT M120K
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Lipscomb, L.A, Drew, D.L, Gassner, N, Baase, W.A, Matthews, B.W.
Deposit date:1997-10-05
Release date:1998-01-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme.
Protein Sci., 7, 1998
200L
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BU of 200l by Molmil
THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W.
Deposit date:1995-11-06
Release date:1996-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme.
J.Mol.Biol., 259, 1996
205L
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BU of 205l by Molmil
HOW AMINO-ACID INSERTIONS ARE ALLOWED IN AN ALPHA-HELIX OF T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Heinz, D.W, Matthews, B.W.
Deposit date:1993-10-12
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme.
Nature, 361, 1993
221L
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BU of 221l by Molmil
THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Blaber, M, Matthews, B.W.
Deposit date:1993-05-28
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme.
Biochemistry, 32, 1993
233L
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BU of 233l by Molmil
T4 LYSOZYME MUTANT M120L
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Lipscomb, L.A, Drew, D.L, Gassner, N, Baase, W.A, Matthews, B.W.
Deposit date:1997-10-07
Release date:1998-01-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme.
Protein Sci., 7, 1998
6XC1
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BU of 6xc1 by Molmil
Crystal structure of bacteriophage T4 spackle and lysozyme in orthorhombic form
Descriptor: 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Lysozyme, ...
Authors:Shi, K, Oakland, J.T, Kurniawan, F, Moeller, N.H, Aihara, H.
Deposit date:2020-06-07
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis of superinfection exclusion by bacteriophage T4 Spackle.
Commun Biol, 3, 2020
6XC0
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BU of 6xc0 by Molmil
Crystal structure of bacteriophage T4 spackle and lysozyme in monoclinic form
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Shi, K, Oakland, J.T, Kurniawan, F, Moeller, N.H, Aihara, H.
Deposit date:2020-06-07
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural basis of superinfection exclusion by bacteriophage T4 Spackle.
Commun Biol, 3, 2020
4XSJ
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BU of 4xsj by Molmil
Crystal structure of the N-terminal domain of the human mitochondrial calcium uniporter fused with T4 lysozyme
Descriptor: Lysozyme,Calcium uniporter protein, mitochondrial, SULFATE ION
Authors:Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H.
Deposit date:2015-01-22
Release date:2015-09-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter.
Embo Rep., 16, 2015
4ZPU
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BU of 4zpu by Molmil
The structure of DLP12 endolysin exhibits likely active and inactive conformations.
Descriptor: ACETATE ION, FORMIC ACID, Lysozyme RrrD
Authors:Kesavan, B, Arockiasamy, A, Krishnaswamy, S.
Deposit date:2015-05-08
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of DLP12 endolysin exhibits likely an active and inactive conformations.
To Be Published
5BZ6
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BU of 5bz6 by Molmil
Crystal structure of the N-terminal domain single mutant (S92A) of the human mitochondrial calcium uniporter fused with T4 lysozyme
Descriptor: Lysozyme,Calcium uniporter protein, mitochondrial, SULFATE ION
Authors:Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H.
Deposit date:2015-06-11
Release date:2015-09-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter.
Embo Rep., 16, 2015
6H9D
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BU of 6h9d by Molmil
Muramidase domain of SpmX from Asticaccaulis excentricus
Descriptor: CHLORIDE ION, GLYCEROL, Lysozyme
Authors:Randich, A.M, Morlot, C.M, Brun, Y.V.
Deposit date:2018-08-03
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Origin of a Core Bacterial Gene via Co-option and Detoxification of a Phage Lysin.
Curr.Biol., 29, 2019
6IIH
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BU of 6iih by Molmil
crystal structure of mitochondrial calcium uptake 2(MICU2)
Descriptor: CALCIUM ION, Endolysin,Calcium uptake protein 2, mitochondrial
Authors:Shen, Q, Wu, W, Zheng, J, Jia, Z.
Deposit date:2018-10-06
Release date:2019-08-14
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.958 Å)
Cite:The crystal structure of MICU2 provides insight into Ca2+binding and MICU1-MICU2 heterodimer formation.
Embo Rep., 20, 2019
6JG0
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BU of 6jg0 by Molmil
Crystal structure of the N-terminal domain single mutant (S92E) of the human mitochondrial calcium uniporter fused with T4 lysozyme
Descriptor: Endolysin,Calcium uniporter protein, SULFATE ION
Authors:Lee, Y, Park, J, Min, C.K, Kang, J.Y, Kim, T.G, Yamamoto, T, Kim, D.H, Eom, S.H.
Deposit date:2019-02-13
Release date:2020-02-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of calcium channel domain
To Be Published
6K69
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BU of 6k69 by Molmil
Application of anti-helix antibodies in protein structure determination (9213-3LRH)
Descriptor: 3LRH intrabody, Engineered T4 lysozyme
Authors:Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y.
Deposit date:2019-06-01
Release date:2019-08-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Application of antihelix antibodies in protein structure determination.
Proc.Natl.Acad.Sci.USA, 116, 2019
6KVX
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BU of 6kvx by Molmil
Crystal structure of the N-terminal domain single mutant (D119A) of the human mitochondrial calcium uniporter fused with T4 lysozyme
Descriptor: Endolysin,Calcium uniporter protein, mitochondrial, SULFATE ION
Authors:Lee, Y, Park, J, Lee, G, Yoon, S, Min, C.K, Kim, T.G, Yamamoto, T, Kim, D.H, Lee, K.W, Eom, S.H.
Deposit date:2019-09-05
Release date:2020-05-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of the N-terminal domain single mutant (D119A) of the human mitochondrial calcium uniporter fused with T4 lysozyme
Sci Rep, 2020
6LZM
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BU of 6lzm by Molmil
COMPARISON OF THE CRYSTAL STRUCTURE OF BACTERIOPHAGE T4 LYSOZYME AT LOW, MEDIUM, AND HIGH IONIC STRENGTHS
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Bell, J.A, Wilson, K, Zhang, X.-J, Faber, H.R, Nicholson, H, Matthews, B.W.
Deposit date:1991-01-25
Release date:1992-07-15
Last modified:2021-06-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comparison of the crystal structure of bacteriophage T4 lysozyme at low, medium, and high ionic strengths.
Proteins, 10, 1991
6PH1
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BU of 6ph1 by Molmil
T4 lysozyme pseudo-wild type soaked in TEMPOL
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Endolysin, ...
Authors:Cuneo, M.J, Myles, D.A, Li, L.
Deposit date:2019-06-25
Release date:2020-07-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.632 Å)
Cite:Making hydrogens stand out: Enhanced neutron diffraction from biological crystals using dynamic nuclear polarization
To be published
4I7R
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BU of 4i7r by Molmil
T4 Lysozyme L99A/M102H with 2-(pyrazolo-1-yl) ethanol bound
Descriptor: 2-(1H-pyrazol-1-yl)ethanol, 2-HYDROXYETHYL DISULFIDE, ACETATE ION, ...
Authors:Merski, M, Shoichet, B.K.
Deposit date:2012-11-30
Release date:2013-03-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:The impact of introducing a histidine into an apolar cavity site on docking and ligand recognition.
J.Med.Chem., 56, 2013
4I7J
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BU of 4i7j by Molmil
T4 Lysozyme L99A/M102H with benzene bound
Descriptor: 2-HYDROXYETHYL DISULFIDE, ACETATE ION, BENZENE, ...
Authors:Merski, M, Shoichet, B.K.
Deposit date:2012-11-30
Release date:2013-03-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:The impact of introducing a histidine into an apolar cavity site on docking and ligand recognition.
J.Med.Chem., 56, 2013
6PGZ
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BU of 6pgz by Molmil
MTSL labelled T4 lysozyme pseudo-wild type V75C mutant
Descriptor: CHLORIDE ION, Endolysin, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:Cuneo, M.J, Myles, D.A, Li, L.
Deposit date:2019-06-25
Release date:2020-07-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Making hydrogens stand out: Enhanced neutron diffraction from biological crystals using dynamic nuclear polarization
To be published
4I7T
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BU of 4i7t by Molmil
T4 Lysozyme L99A/M102H with 2-bromo-5-hydroxybenzaldehyde bound
Descriptor: 2-HYDROXYETHYL DISULFIDE, 2-bromo-5-hydroxybenzaldehyde, ACETATE ION, ...
Authors:Merski, M, Shoichet, B.K.
Deposit date:2012-11-30
Release date:2013-03-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The impact of introducing a histidine into an apolar cavity site on docking and ligand recognition.
J.Med.Chem., 56, 2013

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