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4P2I
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BU of 4p2i by Molmil
Crystal structure of the mouse SNX19 PX domain
Descriptor: MKIAA0254 protein
Authors:Collins, B.M.
Deposit date:2014-03-04
Release date:2014-09-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
4P2J
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BU of 4p2j by Molmil
Crystal structure of the mouse SNX19 PX domain with bound sulphate ion
Descriptor: MKIAA0254 protein, SULFATE ION
Authors:Collins, B.M.
Deposit date:2014-03-04
Release date:2014-09-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
4PQP
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BU of 4pqp by Molmil
Crystal structure of human SNX14 PX domain in space group P43212
Descriptor: GLYCEROL, Sorting nexin-14
Authors:Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B.
Deposit date:2014-03-03
Release date:2014-09-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
4PQO
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BU of 4pqo by Molmil
Structure of the human SNX14 PX domain in space group I41
Descriptor: Sorting nexin-14
Authors:Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B.
Deposit date:2014-03-03
Release date:2014-09-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
2MXC
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BU of 2mxc by Molmil
Solution structure of the full length sorting nexin 3
Descriptor: Sorting nexin-3
Authors:Lenoir, M.M.L, Rajesh, S.S.R, Gruenberg, J.J.G, Overduin, M.M.O, Kaur, J.J.K.
Deposit date:2014-12-20
Release date:2016-05-04
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Phosphorylation of conserved phosphoinositide binding pocket regulates sorting nexin membrane targeting.
Nat Commun, 9, 2018
2REA
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BU of 2rea by Molmil
Crystal structures of C2ALPHA-PI3 kinase PX-domain domain indicate conformational change associated with ligand binding.
Descriptor: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide
Authors:Parkinson, G.N, Vines, D, Driscoll, P.C, Djordjevic, S.
Deposit date:2007-09-26
Release date:2007-11-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of PI3K-C2alpha PX domain indicate conformational change associated with ligand binding
Bmc Struct.Biol., 8, 2008
2RED
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BU of 2red by Molmil
Crystal structures of C2ALPHA-PI3 kinase PX-domain domain indicate conformational change associated with ligand binding.
Descriptor: GLYCEROL, Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide
Authors:Parkinson, G.N, Vines, D, Driscoll, P.C, Djordjevic, S.
Deposit date:2007-09-26
Release date:2007-11-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of PI3K-C2alpha PX domain indicate conformational change associated with ligand binding
Bmc Struct.Biol., 8, 2008
6KOJ
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BU of 6koj by Molmil
Crystal structure of SNX11-PXe domain in complex with PI(3,5)P2
Descriptor: Sorting nexin-11, [(2~{R})-2-butanoyloxy-3-[oxidanyl-[(2~{R},3~{R},5~{S},6~{R})-2,4,6-tris(oxidanyl)-3,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] butanoate
Authors:Xu, T, Liu, J.
Deposit date:2019-08-11
Release date:2020-07-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Molecular Basis for PI(3,5)P2Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation.
J.Mol.Biol., 432, 2020
6KOK
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BU of 6kok by Molmil
Crystal Structure of SNX11/SNX10-PXe Chimera
Descriptor: CHLORIDE ION, SODIUM ION, Sorting nexin-11,Uncharacterized protein SNX10
Authors:Xu, T, Liu, J.
Deposit date:2019-08-11
Release date:2020-07-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Basis for PI(3,5)P2Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation.
J.Mol.Biol., 432, 2020
6KOI
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BU of 6koi by Molmil
Crystal structure of SNX11-PXe domain in dimer form.
Descriptor: Sorting nexin-11
Authors:Xu, T, Xu, J, Liu, J.
Deposit date:2019-08-11
Release date:2020-07-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular Basis for PI(3,5)P2Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation.
J.Mol.Biol., 432, 2020
6MBI
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BU of 6mbi by Molmil
Crystal Structure of SNX15 PX domain in domain swapped conformation form 2
Descriptor: Sorting nexin-15
Authors:Chandra, M, Collins, B.M.
Deposit date:2018-08-29
Release date:2018-09-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.834 Å)
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
6N5X
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BU of 6n5x by Molmil
Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1)
Descriptor: GLYCEROL, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), Sorting nexin-5,Cation-independent mannose-6-phosphate receptor
Authors:Collins, B, Paul, B, Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
6N5Z
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BU of 6n5z by Molmil
Crystal structure of the SNX5 PX domain in complex with the Sema4C
Descriptor: CHLORIDE ION, Sorting nexin-5,Semaphorin-4C
Authors:Collins, B, Paul, B, Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
6N5Y
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BU of 6n5y by Molmil
Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1)
Descriptor: Sorting nexin-5,Cation-independent mannose-6-phosphate receptor
Authors:Collins, B, Paul, B, Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
8AFZ
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BU of 8afz by Molmil
Architecture of the ESCPE-1 membrane coat
Descriptor: Cation-independent mannose-6-phosphate receptor, Sorting nexin-1, Sorting nexin-5
Authors:Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E, Ishida, M, Williamsom, C.D, Banos-Mateos, S, Gil-Carton, D, Romero, M, Vidaurrazaga, A, Fernandez-Recio, J, Rojas, A.L, Bonifacino, J.S, Castano-Diez, D, Hierro, A.
Deposit date:2022-07-18
Release date:2023-06-21
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Architecture of the ESCPE-1 membrane coat.
Nat.Struct.Mol.Biol., 30, 2023
6Q0X
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BU of 6q0x by Molmil
The cryo-EM structure of the SNX-BAR Mvp1 tetramer
Descriptor: Sorting nexin MVP1
Authors:Sun, D, Ford, M.G.J, Zhang, P.
Deposit date:2019-08-02
Release date:2020-04-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The cryo-EM structure of the SNX-BAR Mvp1 tetramer.
Nat Commun, 11, 2020
7D6D
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BU of 7d6d by Molmil
Structural insights into membrane remodeling by SNX1
Descriptor: Sorting nexin-1
Authors:Zhang, Y, Pang, X, Sun, F.
Deposit date:2020-09-30
Release date:2021-03-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structural insights into membrane remodeling by SNX1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7D6E
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BU of 7d6e by Molmil
Structural insights into membrane remodeling by SNX1
Descriptor: Sorting nexin-1
Authors:Zhang, Y, Pang, X, Sun, F.
Deposit date:2020-09-30
Release date:2021-03-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structural insights into membrane remodeling by SNX1.
Proc.Natl.Acad.Sci.USA, 118, 2021
6H7W
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BU of 6h7w by Molmil
Model of retromer-Vps5 complex assembled on membrane.
Descriptor: Putative vacuolar protein sorting-associated protein, Vacuolar protein sorting-associated protein 26-like protein, Vacuolar protein sorting-associated protein 29, ...
Authors:Kovtun, O, Leneva, N, Ariotti, N, Rohan, T.S, Owen, D.J, Briggs, J.A.G, Collins, B.M.
Deposit date:2018-07-31
Release date:2018-09-26
Last modified:2018-10-10
Method:ELECTRON MICROSCOPY (11.4 Å)
Cite:Structure of the membrane-assembled retromer coat determined by cryo-electron tomography.
Nature, 561, 2018
4AKV
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BU of 4akv by Molmil
Crystal structure of human sorting nexin 33 (SNX33)
Descriptor: SORTING NEXIN-33, SULFATE ION
Authors:Oberholzer, A, Froese, D.S, Krojer, T, Shrestha, L, Filippakopoulos, P, Muniz, J.R.C, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Yue, W.W.
Deposit date:2012-02-29
Release date:2012-08-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.651 Å)
Cite:Structure of Human Sorting Nexin 33
To be Published
7BLO
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BU of 7blo by Molmil
VPS26 dimer region of metazoan membrane-assembled retromer:SNX3 complex modelled with human proteins
Descriptor: 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, C-term (residues 493-54) of Wls (fitted sequence corresponds to hDMT1-II), Sorting nexin-3, ...
Authors:Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J.
Deposit date:2021-01-18
Release date:2021-03-03
Last modified:2021-04-07
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
7BLQ
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BU of 7blq by Molmil
Vps26 dimer region of the fungal membrane-assembled retromer:Grd19 complex.
Descriptor: 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, Sorting nexin-3, The C-terminal portion of Kex2 cargo, ...
Authors:Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J.
Deposit date:2021-01-18
Release date:2021-03-03
Last modified:2021-04-07
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
3DYU
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BU of 3dyu by Molmil
Crystal structure of Snx9PX-BAR (230-595), H32
Descriptor: Sorting nexin-9
Authors:Wang, Q, Kaan, H.Y.K, Sondermann, H.
Deposit date:2008-07-28
Release date:2008-09-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structure and plasticity of endophilin and sorting nexin 9.
Structure, 16, 2008
3DYT
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BU of 3dyt by Molmil
Crystal structure of Snx9PX-BAR (230-595), C2221
Descriptor: SULFATE ION, Sorting nexin-9
Authors:Wang, Q, Kaan, H.Y.K, Sondermann, H.
Deposit date:2008-07-28
Release date:2008-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structure and plasticity of endophilin and sorting nexin 9.
Structure, 16, 2008
5F0P
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BU of 5f0p by Molmil
Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1(L557M) (SeMet labeled)
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Natural resistance-associated macrophage protein 2, ...
Authors:Lucas, M, Gershlick, D, Vidaurrazaga, A, Rojas, A.L, Bonifacino, J.S, Hierro, A.
Deposit date:2015-11-27
Release date:2016-12-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural Mechanism for Cargo Recognition by the Retromer Complex.
Cell, 167, 2016

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