4P2I
| Crystal structure of the mouse SNX19 PX domain | Descriptor: | MKIAA0254 protein | Authors: | Collins, B.M. | Deposit date: | 2014-03-04 | Release date: | 2014-09-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling. J.Biol.Chem., 289, 2014
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4P2J
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4PQP
| Crystal structure of human SNX14 PX domain in space group P43212 | Descriptor: | GLYCEROL, Sorting nexin-14 | Authors: | Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B. | Deposit date: | 2014-03-03 | Release date: | 2014-09-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling. J.Biol.Chem., 289, 2014
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4PQO
| Structure of the human SNX14 PX domain in space group I41 | Descriptor: | Sorting nexin-14 | Authors: | Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B. | Deposit date: | 2014-03-03 | Release date: | 2014-09-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling. J.Biol.Chem., 289, 2014
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2MXC
| Solution structure of the full length sorting nexin 3 | Descriptor: | Sorting nexin-3 | Authors: | Lenoir, M.M.L, Rajesh, S.S.R, Gruenberg, J.J.G, Overduin, M.M.O, Kaur, J.J.K. | Deposit date: | 2014-12-20 | Release date: | 2016-05-04 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Phosphorylation of conserved phosphoinositide binding pocket regulates sorting nexin membrane targeting. Nat Commun, 9, 2018
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2REA
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2RED
| Crystal structures of C2ALPHA-PI3 kinase PX-domain domain indicate conformational change associated with ligand binding. | Descriptor: | GLYCEROL, Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide | Authors: | Parkinson, G.N, Vines, D, Driscoll, P.C, Djordjevic, S. | Deposit date: | 2007-09-26 | Release date: | 2007-11-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of PI3K-C2alpha PX domain indicate conformational change associated with ligand binding Bmc Struct.Biol., 8, 2008
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6KOJ
| Crystal structure of SNX11-PXe domain in complex with PI(3,5)P2 | Descriptor: | Sorting nexin-11, [(2~{R})-2-butanoyloxy-3-[oxidanyl-[(2~{R},3~{R},5~{S},6~{R})-2,4,6-tris(oxidanyl)-3,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] butanoate | Authors: | Xu, T, Liu, J. | Deposit date: | 2019-08-11 | Release date: | 2020-07-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Molecular Basis for PI(3,5)P2Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation. J.Mol.Biol., 432, 2020
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6KOK
| Crystal Structure of SNX11/SNX10-PXe Chimera | Descriptor: | CHLORIDE ION, SODIUM ION, Sorting nexin-11,Uncharacterized protein SNX10 | Authors: | Xu, T, Liu, J. | Deposit date: | 2019-08-11 | Release date: | 2020-07-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular Basis for PI(3,5)P2Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation. J.Mol.Biol., 432, 2020
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6KOI
| Crystal structure of SNX11-PXe domain in dimer form. | Descriptor: | Sorting nexin-11 | Authors: | Xu, T, Xu, J, Liu, J. | Deposit date: | 2019-08-11 | Release date: | 2020-07-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Molecular Basis for PI(3,5)P2Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation. J.Mol.Biol., 432, 2020
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6MBI
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6N5X
| Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1) | Descriptor: | GLYCEROL, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), Sorting nexin-5,Cation-independent mannose-6-phosphate receptor | Authors: | Collins, B, Paul, B, Weeratunga, S. | Deposit date: | 2018-11-22 | Release date: | 2019-09-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.051 Å) | Cite: | Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins. Nat.Cell Biol., 21, 2019
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6N5Z
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6N5Y
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8AFZ
| Architecture of the ESCPE-1 membrane coat | Descriptor: | Cation-independent mannose-6-phosphate receptor, Sorting nexin-1, Sorting nexin-5 | Authors: | Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E, Ishida, M, Williamsom, C.D, Banos-Mateos, S, Gil-Carton, D, Romero, M, Vidaurrazaga, A, Fernandez-Recio, J, Rojas, A.L, Bonifacino, J.S, Castano-Diez, D, Hierro, A. | Deposit date: | 2022-07-18 | Release date: | 2023-06-21 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Architecture of the ESCPE-1 membrane coat. Nat.Struct.Mol.Biol., 30, 2023
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6Q0X
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7D6D
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7D6E
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6H7W
| Model of retromer-Vps5 complex assembled on membrane. | Descriptor: | Putative vacuolar protein sorting-associated protein, Vacuolar protein sorting-associated protein 26-like protein, Vacuolar protein sorting-associated protein 29, ... | Authors: | Kovtun, O, Leneva, N, Ariotti, N, Rohan, T.S, Owen, D.J, Briggs, J.A.G, Collins, B.M. | Deposit date: | 2018-07-31 | Release date: | 2018-09-26 | Last modified: | 2018-10-10 | Method: | ELECTRON MICROSCOPY (11.4 Å) | Cite: | Structure of the membrane-assembled retromer coat determined by cryo-electron tomography. Nature, 561, 2018
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4AKV
| Crystal structure of human sorting nexin 33 (SNX33) | Descriptor: | SORTING NEXIN-33, SULFATE ION | Authors: | Oberholzer, A, Froese, D.S, Krojer, T, Shrestha, L, Filippakopoulos, P, Muniz, J.R.C, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Yue, W.W. | Deposit date: | 2012-02-29 | Release date: | 2012-08-01 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.651 Å) | Cite: | Structure of Human Sorting Nexin 33 To be Published
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7BLO
| VPS26 dimer region of metazoan membrane-assembled retromer:SNX3 complex modelled with human proteins | Descriptor: | 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, C-term (residues 493-54) of Wls (fitted sequence corresponds to hDMT1-II), Sorting nexin-3, ... | Authors: | Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J. | Deposit date: | 2021-01-18 | Release date: | 2021-03-03 | Last modified: | 2021-04-07 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly. Sci Adv, 7, 2021
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7BLQ
| Vps26 dimer region of the fungal membrane-assembled retromer:Grd19 complex. | Descriptor: | 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, Sorting nexin-3, The C-terminal portion of Kex2 cargo, ... | Authors: | Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J. | Deposit date: | 2021-01-18 | Release date: | 2021-03-03 | Last modified: | 2021-04-07 | Method: | ELECTRON MICROSCOPY (9.2 Å) | Cite: | Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly. Sci Adv, 7, 2021
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3DYU
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3DYT
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5F0P
| Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1(L557M) (SeMet labeled) | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Natural resistance-associated macrophage protein 2, ... | Authors: | Lucas, M, Gershlick, D, Vidaurrazaga, A, Rojas, A.L, Bonifacino, J.S, Hierro, A. | Deposit date: | 2015-11-27 | Release date: | 2016-12-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Structural Mechanism for Cargo Recognition by the Retromer Complex. Cell, 167, 2016
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