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7KM9	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001913, tetragonal crystal from Descriptor: (2R)-2-[(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)methyl]-3,3-difluoropropanoic acid, BROMIDE ION, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-11-02 Release date: 2021-07-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001913, tetragonal crystal form to be published
7KM8	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001914, orthorhombic crystal from Descriptor: (2S)-2-[(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)methyl]-3,3-difluoropropanoic acid, CHLORIDE ION, Dihydrofolate reductase, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-11-02 Release date: 2021-07-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001914, orthorhombic crystal form to be published
7KM7	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001914, tetragonal crystal from Descriptor: (2S)-2-[(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)methyl]-3,3-difluoropropanoic acid, BROMIDE ION, Dihydrofolate reductase, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-11-02 Release date: 2021-07-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001914, tetragonal crystal form to be published
7KI9	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001912 Descriptor: 1-[2-(3-{[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]methyl}azetidin-1-yl)phenyl]piperidine-4-carboxylic acid, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-10-23 Release date: 2021-07-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001912 to be published
7KI8	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001580 Descriptor: 1-[2-({3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propyl}amino)phenyl]piperidine-4-carboxylic acid, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-10-23 Release date: 2021-07-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001580 to be published
7K6C	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium abscessus ATCC 19977 / DSM 44196 with NADP and inhibitor P218 Descriptor: 1,2-ETHANEDIOL, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-09-19 Release date: 2021-03-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium abscessus ATCC 19977 / DSM 44196 with NADP and inhibitor P218 to be published
7K6A	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001575 Descriptor: 1,2-ETHANEDIOL, 6-ethyl-5-[3-({3-[4-(trifluoromethyl)piperidin-1-yl]pyridin-2-yl}oxy)propoxy]pyrimidine-2,4-diamine, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-09-19 Release date: 2021-03-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001575 to be published
7K69	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001574 Descriptor: 1-{2-[2-(2,4-diamino-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl)-2-oxoethoxy]phenyl}piperidine-4-carboxylic acid, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-09-19 Release date: 2021-03-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001574 To Be Published
7K68	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001565 Descriptor: 3-(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, CHLORIDE ION, Dihydrofolate reductase, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-09-19 Release date: 2021-03-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor SDDC-0001565 To Be Published
7K62	Crystal Structure of Dihydrofolate reductase from Mycobacterium kansasii in complex with NADP and inhibitor P218 Descriptor: 1,2-ETHANEDIOL, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, Dihydrofolate reductase, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-09-18 Release date: 2021-03-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Crystal Structure of Dihydrofolate reductase from Mycobacterium kansasii in complex with NADP and inhibitor P218 To Be Published
7FQG	DHFR:NADP+:FOL complex (crystal 2, pass 5, 295 K) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Single-crystal, multi-temperature experiment of DHFR:NADP+:FOL complex To Be Published
7FQF	DHFR:NADP+:FOL complex (crystal 2, pass 4, 310 K) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.23 Å) Cite: Single-crystal, multi-temperature experiment of DHFR:NADP+:FOL complex To Be Published
7FQE	DHFR:NADP+:FOL complex (crystal 2, pass 3, 295 K) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.18 Å) Cite: Single-crystal, multi-temperature experiment of DHFR:NADP+:FOL complex To Be Published
7FQD	DHFR:NADP+:FOL complex (crystal 2, pass 2, 280 K) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.17 Å) Cite: Single-crystal, multi-temperature experiment of DHFR:NADP+:FOL complex To Be Published
7FQC	DHFR:NADP+:FOL complex (crystal 2, pass 1, 295 K) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.18 Å) Cite: Single-crystal, multi-temperature experiment of DHFR:NADP+:FOL complex To Be Published
7FQB	DHFR:NADP+:FOL complex (crystal 1, pass 5, 295 K) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.14 Å) Cite: Single-crystal, multi-temperature experiment of DHFR:NADP+:FOL complex To Be Published
7FQA	DHFR:NADP+:FOL complex (crystal 1, pass 4, 280 K) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.08 Å) Cite: Single-crystal, multi-temperature experiment of DHFR:NADP+:FOL complex To Be Published
7FQ9	DHFR:NADP+:FOL complex (crystal 1, pass 3, 295 K) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.11 Å) Cite: Single-crystal, multi-temperature experiment of DHFR:NADP+:FOL complex To Be Published
7FQ8	DHFR:NADP+:FOL complex (crystal 1, pass 2, 310 K) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.21 Å) Cite: Single-crystal, multi-temperature experiment of DHFR:NADP+:FOL complex To Be Published
7FQ7	DHFR:NADP+:FOL complex (crystal 1, pass 1, 295 K) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Single-crystal, multi-temperature experiment of DHFR:NADP+:FOL complex To Be Published
7FQ6	DHFR:NADP+:FOL complex at 310 K (multi-crystal) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.29 Å) Cite: DHFR:NADP+:FOL complex at 310 K To Be Published
7FQ5	DHFR:NADP+:FOL complex at 310 K (crystal 3) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.35 Å) Cite: DHFR:NADP+:FOL complex at 310 K To Be Published
7FQ4	DHFR:NADP+:FOL complex at 310 K (crystal 2) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.33 Å) Cite: DHFR:NADP+:FOL complex at 310 K To Be Published
7FQ3	DHFR:NADP+:FOL complex at 310 K (crystal 1) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.3 Å) Cite: DHFR:NADP+:FOL complex at 310 K To Be Published
7FQ2	DHFR:NADP+:FOL complex at 300 K (multi-crystal) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-10 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (1.07 Å) Cite: DHFR:NADP+:FOL complex at 300 K To Be Published

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