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2P0F
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BU of 2p0f by Molmil
ArhGAP9 PH domain in complex with Ins(1,3,5)P3
Descriptor: PHOSPHATE ION, Rho GTPase-activating protein 9
Authors:Ceccarelli, D.F.J, Blasutig, I, Goudreault, M, Ruston, J, Pawson, T, Sicheri, F.
Deposit date:2007-02-28
Release date:2007-03-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9.
J.Biol.Chem., 282, 2007
2OTX
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BU of 2otx by Molmil
Crystal Structure of A N-terminal Fragment of SKAP-HOM Containing both the Helical Dimerization Domain and the PH Domain
Descriptor: Src kinase-associated phosphoprotein 2
Authors:Tang, Y, Swanson, K.D, Neel, B.G, Eck, M.J.
Deposit date:2007-02-09
Release date:2007-03-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Skap-hom dimerization and PH domains comprise a 3'-phosphoinositide-gated molecular switch.
Mol.Cell, 32, 2008
2P0H
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BU of 2p0h by Molmil
ArhGAP9 PH domain in complex with Ins(1,3,4)P3
Descriptor: (1S,3S,4S)-1,3,4-TRIPHOSPHO-MYO-INOSITOL, Rho GTPase-activating protein 9
Authors:Ceccarelli, D.F.J, Blasutig, I, Goudreault, M, Ruston, J, Pawson, T, Sicheri, F.
Deposit date:2007-02-28
Release date:2007-03-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9.
J.Biol.Chem., 282, 2007
2P0D
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BU of 2p0d by Molmil
ArhGAP9 PH domain in complex with Ins(1,4,5)P3
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Rho GTPase-activating protein 9
Authors:Ceccarelli, D.F.J, Blasutig, I, Goudreault, M, Ruston, J, Pawson, T, Sicheri, F.
Deposit date:2007-02-28
Release date:2007-03-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.811 Å)
Cite:Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9.
J.Biol.Chem., 282, 2007
2RSG
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BU of 2rsg by Molmil
Solution structure of the CERT PH domain
Descriptor: Collagen type IV alpha-3-binding protein
Authors:Sugiki, T, Takeuchi, K, Tokunaga, Y, Kumagai, K, Kawano, M, Nishijima, M, Hanada, K, Takahashi, H, Shimada, I.
Deposit date:2012-02-25
Release date:2012-08-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis for the Golgi association by the pleckstrin homology domain of the ceramide trafficking protein (CERT)
J.Biol.Chem., 287, 2012
2UZR
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A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K)
Descriptor: RAC-alpha serine/threonine-protein kinase
Authors:Carpten, J.D, Faber, A.L, Horn, C, Donoho, G.P, Briggs, S.L, Robbins, C.M, Hostetter, G, Boguslawski, S, Moses, T.Y, Savage, S, Uhlik, M, Lin, A, Du, J, Qian, Y.W, Zeckner, D.J, Tucker-Kellogg, G, Touchman, J, Patel, K, Mousses, S, Bittner, M, Schevitz, R, Lai, M.H, Blanchard, K.L, Thomas, J.E.
Deposit date:2007-05-01
Release date:2007-07-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature, 448, 2007
2UZS
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A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K)
Descriptor: INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, RAC-alpha serine/threonine-protein kinase
Authors:Carpten, J.D, Faber, A.L, Horn, C, Donoho, G.P, Briggs, S.L, Robbins, C.M, Hostetter, G, Boguslawski, S, Moses, T.Y, Savage, S, Uhlik, M, Lin, A, Du, J, Qian, Y.W, Zeckner, D.J, Tucker-Kellogg, G, Touchman, J, Patel, K, Mousses, S, Bittner, M, Schevitz, R, Lai, M.H, Blanchard, K.L, Thomas, J.E.
Deposit date:2007-05-01
Release date:2007-07-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature, 448, 2007
2UVM
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Structure of PKBalpha PH domain in complex with a novel inositol headgroup surrogate, benzene 1,2,3,4-tetrakisphosphate
Descriptor: BENZENE-1,2,3,4-TETRAYL TETRAKIS[DIHYDROGEN (PHOSPHATE)], RAC-ALPHA SERINE/THREONINE-PROTEIN KINASE, SODIUM ION
Authors:Komander, D, Mills, S.J, Trusselle, M.N, Safrany, S.T, van Aalten, D.M.F, Potter, B.V.L.
Deposit date:2007-03-12
Release date:2007-04-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Novel Inositol Phospholipid Headgroup Surrogate Crystallised in the Pleckstrin Homology Domain of Protein Kinase Balpha.
Acs Chem.Biol., 2, 2007
2COD
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BU of 2cod by Molmil
Solution structure of the N-terminal PH domain of ARAP2 protein from human
Descriptor: Centaurin-delta 1
Authors:Li, H, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-17
Release date:2005-11-17
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal PH domain of ARAP2 protein from human
To be Published
2COF
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BU of 2cof by Molmil
Solution structure of the C-terminal PH domain of hypothetical protein KIAA1914 from human
Descriptor: Protein KIAA1914
Authors:Li, H, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-17
Release date:2005-11-17
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the C-terminal PH domain of hypothetical protein KIAA1914 from human
To be Published
2COA
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BU of 2coa by Molmil
Solution structure of the PH domain of protein kinase C, D2 type from human
Descriptor: Protein kinase C, D2 type
Authors:Li, H, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-17
Release date:2005-11-17
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of protein kinase C, D2 type from human
To be Published
2D9V
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BU of 2d9v by Molmil
Solution structure of the PH domain of Pleckstrin homology domain-containing protein family B member 1 from mouse
Descriptor: Pleckstrin homology domain-containing protein family B member 1
Authors:Li, H, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-13
Release date:2006-06-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of Pleckstrin homology domain-containing protein family B member 1 from mouse
To be Published
2D9Z
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BU of 2d9z by Molmil
Solution structure of the PH domain of Protein kinase C, nu type from human
Descriptor: Protein kinase C, nu type
Authors:Li, H, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-13
Release date:2007-01-02
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of Protein kinase C, nu type from human
To be Published
2D9X
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BU of 2d9x by Molmil
Solution structure of the PH domain of Oxysterol binding protein-related protein 11 from human
Descriptor: Oxysterol binding protein-related protein 11
Authors:Li, H, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-13
Release date:2006-06-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of Oxysterol binding protein-related protein 11 from human
To be Published
2DA0
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BU of 2da0 by Molmil
Solution structure of the PH domain of PIP2-dependent ARF1 GTPase-activating protein from human
Descriptor: 130-kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein
Authors:Li, H, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-13
Release date:2006-06-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of PIP2-dependent ARF1 GTPase-activating protein from human
To be Published
2D9Y
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BU of 2d9y by Molmil
Solution structure of the PH domain of PEPP-3 from human
Descriptor: Pleckstrin homology domain-containing protein family A member 6
Authors:Li, H, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-13
Release date:2006-06-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of PEPP-3 from human
To be Published
2DKP
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BU of 2dkp by Molmil
Solution structure of the PH domain of pleckstrin homology domain-containing protein family A member 5 from human
Descriptor: Pleckstrin homology domain-containing family A member 5
Authors:Li, H, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-13
Release date:2006-10-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of pleckstrin homology domain-containing protein family A member 5 from human
To be Published
2DHI
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BU of 2dhi by Molmil
Solution structure of the PH domain of Evectin-2 from mouse
Descriptor: Pleckstrin homology domain-containing family B member 2
Authors:Li, H, Yoneyama, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-24
Release date:2006-09-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of Evectin-2 from mouse
To be Published
2DN6
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BU of 2dn6 by Molmil
Solution structure of the PH domain of KIAA0640 protein from human
Descriptor: KIAA0640 protein
Authors:Li, H, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-25
Release date:2006-10-25
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of KIAA0640 protein from human
To be Published
2DTC
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Crystal structure of MS0666
Descriptor: RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR RALGPS1A
Authors:Wang, H, Kishishita, S, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-07-12
Release date:2007-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of MS0666
To be Published
2DHJ
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BU of 2dhj by Molmil
Solution structure of the PH domain of Rho GTPase activating protein 21 from human
Descriptor: Rho GTPase activating protein 21
Authors:Li, H, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-24
Release date:2006-09-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of Rho GTPase activating protein 21 from human
To be Published
2DHK
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Solution structure of the PH domain of TBC1 domain family member 2 protein from human
Descriptor: TBC1 domain family member 2
Authors:Li, H, Tochio, N, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-24
Release date:2006-09-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of TBC1 domain family member 2 protein from human
To be Published
2DYN
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DYNAMIN (PLECKSTRIN HOMOLOGY DOMAIN) (DYNPH)
Descriptor: DYNAMIN
Authors:Timm, D.E.
Deposit date:1997-07-21
Release date:1997-11-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the pleckstrin homology domain from dynamin.
Nat.Struct.Biol., 1, 1994
1U5E
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BU of 1u5e by Molmil
Crystal Structure of a N-terminal Fragment of SKAP-Hom Containing Both the Helical Dimerization Domain and the PH Domain
Descriptor: Src-associated adaptor protein
Authors:Tang, Y, Swanson, K.D, Neel, B.G, Eck, M.J.
Deposit date:2004-07-27
Release date:2005-07-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for the Dimerization and Phosphoinositide Specificity of the Src Kinase-associated Phosphoproteins SKAP55 and SKAP-Hom
To be Published
1U2B
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BU of 1u2b by Molmil
Triglycine variant of the Grp1 Pleckstrin Homology Domain unliganded
Descriptor: Cytohesin 3, SULFATE ION
Authors:Cronin, T.C, DiNitto, J.P, Czech, M.P, Lambright, D.G.
Deposit date:2004-07-16
Release date:2005-02-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains
Embo J., 23, 2004

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