2RQ9
| Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new | Descriptor: | Heparin-binding growth factor 1 | Authors: | Enomoto, M, Xiang, L, Ishii, T, Tochio, N, Hosoda, K, Inoue, Y, Nameki, N, Wakamatsu, K. | Deposit date: | 2009-03-12 | Release date: | 2010-03-16 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new To be Published
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2UUS
| Crystal structure of the rat FGF1-sucrose octasulfate (SOS) complex. | Descriptor: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, HEPARIN-BINDING GROWTH FACTOR 1 | Authors: | Kulahin, N, Kiselyov, V, Kochoyan, A, Kristensen, O, Berezin, V, Bock, E, Gajhede, M. | Deposit date: | 2007-03-07 | Release date: | 2008-05-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Dimerization Effect of Sucrose Octasulfate on Rat Fgf1. Acta Crystallogr.,Sect.F, 64, 2008
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1BLD
| BASIC FIBROBLAST GROWTH FACTOR (FGF-2) MUTANT WITH CYS 78 REPLACED BY SER AND CYS 96 REPLACED BY SER, NMR | Descriptor: | BASIC FIBROBLAST GROWTH FACTOR | Authors: | Powers, R, Seddon, A.P, Bohlen, P, Moy, F.J. | Deposit date: | 1996-05-20 | Release date: | 1996-11-08 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | High-resolution solution structure of basic fibroblast growth factor determined by multidimensional heteronuclear magnetic resonance spectroscopy. Biochemistry, 35, 1996
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1DZC
| High resolution structure of acidic fibroblast growth factor. Mutant FGF-4-ALA-(24-154), 24 NMR structures | Descriptor: | FIBROBLAST GROWTH FACTOR 1 | Authors: | Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G. | Deposit date: | 2000-02-24 | Release date: | 2000-03-16 | Last modified: | 2013-05-15 | Method: | SOLUTION NMR | Cite: | 1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor Biochemistry, 39, 2000
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1DZD
| High resolution structure of acidic fibroblast growth factor (27-154), 24 NMR structures | Descriptor: | ACIDIC FIBROBLAST GROWTH FACTOR | Authors: | Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G. | Deposit date: | 2000-02-24 | Release date: | 2000-03-16 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | 1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor Biochemistry, 39, 2000
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1FGA
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1FMM
| SOLUTION STRUCTURE OF NFGF-1 | Descriptor: | ACIDIC FIBROBLAST GROWTH FACTOR | Authors: | Arunkumar, A.I, Srisailam, S, Kumar, T.K.S, Chiu, I.M, Yu, C. | Deposit date: | 2000-08-18 | Release date: | 2001-08-18 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Structure and stability of an acidic fibroblast growth factor from Notophthalmus viridescens. J.Biol.Chem., 277, 2002
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1G82
| STRUCTURE OF FIBROBLAST GROWTH FACTOR 9 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, FIBROBLAST GROWTH FACTOR 9, ... | Authors: | Hecht, H.J, Adar, R, Hofmann, B, Bogin, O, Weich, H, Yayon, A. | Deposit date: | 2000-11-16 | Release date: | 2001-03-07 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of fibroblast growth factor 9 shows a symmetric dimer with unique receptor- and heparin-binding interfaces. Acta Crystallogr.,Sect.D, 57, 2001
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2ERM
| Solution structure of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue | Descriptor: | 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, ISOPROPYL ALCOHOL | Authors: | Canales, A, Lozano, R, Nieto, P.M, Martin-Lomas, M, Gimenez-Gallego, G, Jimenez-Barbero, J. | Deposit date: | 2005-10-25 | Release date: | 2006-10-03 | Last modified: | 2020-07-29 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of a human FGF-1 monomer, activated by a hexasaccharide heparin-analogue. Febs J., 273, 2006
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2FGF
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1NZK
| Crystal Structure of a Multiple Mutant (L44F, L73V, V109L, L111I, C117V) of Human Acidic Fibroblast Growth Factor | Descriptor: | Acidic Fibroblast Growth Factor, FORMIC ACID, SULFATE ION | Authors: | Brych, S.R, Kim, J, Logan, T.M, Blaber, M. | Deposit date: | 2003-02-18 | Release date: | 2004-03-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Accommodation of a highly symmetric core within a symmetric protein superfold. Protein Sci., 12, 2003
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1P63
| Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I) | Descriptor: | ACIDIC FIBROBLAST GROWTH FACTOR, FORMIC ACID, SULFATE ION | Authors: | Brych, S.R, Kim, J, Logan, T.M, Blaber, M. | Deposit date: | 2003-04-28 | Release date: | 2004-05-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Accommodation of a highly symmetric core within a symmetric protein
superfold Protein Sci., 12, 2003
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2HWA
| Crystal structure of Lys12Thr/Cys117Val mutant of human acidic fibroblast growth factor at 1.65 angstrom resolution. | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | Deposit date: | 2006-08-01 | Release date: | 2007-06-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions. J.Mol.Biol., 371, 2007
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2HW9
| Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution. | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | Deposit date: | 2006-08-01 | Release date: | 2007-06-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions. J.Mol.Biol., 371, 2007
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2HWM
| Crystal structure of Lys12Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.60 angstrom resolution | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1 | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | Deposit date: | 2006-08-01 | Release date: | 2007-06-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions. J.Mol.Biol., 371, 2007
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1PZZ
| Crystal structure of FGF-1, V51N mutant | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | Authors: | Kim, J, Blaber, M. | Deposit date: | 2003-07-14 | Release date: | 2004-07-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor Protein Sci., 14, 2005
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1Q03
| Crystal structure of FGF-1, S50G/V51G mutant | Descriptor: | Heparin-binding growth factor 1 | Authors: | Kim, J, Blaber, M. | Deposit date: | 2003-07-15 | Release date: | 2004-07-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor Protein Sci., 14, 2005
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1Q04
| Crystal structure of FGF-1, S50E/V51N | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1 | Authors: | Kim, J, Blaber, M. | Deposit date: | 2003-07-15 | Release date: | 2004-07-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor Protein Sci., 14, 2005
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1PWA
| Crystal structure of Fibroblast Growth Factor 19 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fibroblast growth factor-19, GLYCEROL, ... | Authors: | Harmer, N.J, Pellegrini, L, Chirgadze, D, Fernandez-Recio, J, Blundell, T.L. | Deposit date: | 2003-07-01 | Release date: | 2004-01-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity. Biochemistry, 43, 2004
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2HZ9
| Crystal structure of Lys12Val/Asn95Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.70 angstrom resolution. | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | Deposit date: | 2006-08-08 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions J.Mol.Biol., 371, 2007
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1Q1U
| Crystal structure of human FHF1b (FGF12b) | Descriptor: | SULFATE ION, fibroblast growth factor homologous factor 1 | Authors: | Olsen, S.K, Garbi, M, Zampieri, N, Eliseenkova, A.V, Ornitz, D.M, Goldfarb, M, Mohammadi, M. | Deposit date: | 2003-07-22 | Release date: | 2003-08-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs J.Biol.Chem., 278, 2003
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1QQL
| THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7/1 CHIMERA | Descriptor: | FIBROBLAST GROWTH FACTOR 7/1 CHIMERA | Authors: | Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L. | Deposit date: | 1999-06-07 | Release date: | 2000-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. Biochemistry, 40, 2001
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1QQK
| THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7 (KERATINOCYTE GROWTH FACTOR) | Descriptor: | FIBROBLAST GROWTH FACTOR 7 | Authors: | Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L. | Deposit date: | 1999-06-07 | Release date: | 2000-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. Biochemistry, 40, 2001
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2J3P
| crystal structure of rat FGF1 at 1.4 A | Descriptor: | HEPARIN-BINDING GROWTH FACTOR 1, SULFATE ION | Authors: | Kulahin, N, Kristensen, O, Berezin, V, Gajhede, M, Bock, E. | Deposit date: | 2006-08-22 | Release date: | 2007-02-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of Rat Acidic Fibroblast Growth Factor at 1.4 A Resolution. Acta Crystallogr.,Sect.F, 63, 2007
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2K43
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