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2RQ9
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Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new
Descriptor: Heparin-binding growth factor 1
Authors:Enomoto, M, Xiang, L, Ishii, T, Tochio, N, Hosoda, K, Inoue, Y, Nameki, N, Wakamatsu, K.
Deposit date:2009-03-12
Release date:2010-03-16
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new
To be Published
2UUS
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Crystal structure of the rat FGF1-sucrose octasulfate (SOS) complex.
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, HEPARIN-BINDING GROWTH FACTOR 1
Authors:Kulahin, N, Kiselyov, V, Kochoyan, A, Kristensen, O, Berezin, V, Bock, E, Gajhede, M.
Deposit date:2007-03-07
Release date:2008-05-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Dimerization Effect of Sucrose Octasulfate on Rat Fgf1.
Acta Crystallogr.,Sect.F, 64, 2008
1BLD
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BASIC FIBROBLAST GROWTH FACTOR (FGF-2) MUTANT WITH CYS 78 REPLACED BY SER AND CYS 96 REPLACED BY SER, NMR
Descriptor: BASIC FIBROBLAST GROWTH FACTOR
Authors:Powers, R, Seddon, A.P, Bohlen, P, Moy, F.J.
Deposit date:1996-05-20
Release date:1996-11-08
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:High-resolution solution structure of basic fibroblast growth factor determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry, 35, 1996
1DZC
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High resolution structure of acidic fibroblast growth factor. Mutant FGF-4-ALA-(24-154), 24 NMR structures
Descriptor: FIBROBLAST GROWTH FACTOR 1
Authors:Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G.
Deposit date:2000-02-24
Release date:2000-03-16
Last modified:2013-05-15
Method:SOLUTION NMR
Cite:1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor
Biochemistry, 39, 2000
1DZD
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High resolution structure of acidic fibroblast growth factor (27-154), 24 NMR structures
Descriptor: ACIDIC FIBROBLAST GROWTH FACTOR
Authors:Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G.
Deposit date:2000-02-24
Release date:2000-03-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor
Biochemistry, 39, 2000
1FGA
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REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION
Descriptor: BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, SELENATE ION
Authors:Eriksson, A.E, Matthews, B.W.
Deposit date:1993-02-26
Release date:1993-07-15
Last modified:2020-07-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution.
Protein Sci., 2, 1993
1FMM
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SOLUTION STRUCTURE OF NFGF-1
Descriptor: ACIDIC FIBROBLAST GROWTH FACTOR
Authors:Arunkumar, A.I, Srisailam, S, Kumar, T.K.S, Chiu, I.M, Yu, C.
Deposit date:2000-08-18
Release date:2001-08-18
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structure and stability of an acidic fibroblast growth factor from Notophthalmus viridescens.
J.Biol.Chem., 277, 2002
1G82
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STRUCTURE OF FIBROBLAST GROWTH FACTOR 9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, FIBROBLAST GROWTH FACTOR 9, ...
Authors:Hecht, H.J, Adar, R, Hofmann, B, Bogin, O, Weich, H, Yayon, A.
Deposit date:2000-11-16
Release date:2001-03-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of fibroblast growth factor 9 shows a symmetric dimer with unique receptor- and heparin-binding interfaces.
Acta Crystallogr.,Sect.D, 57, 2001
2ERM
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Solution structure of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue
Descriptor: 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, ISOPROPYL ALCOHOL
Authors:Canales, A, Lozano, R, Nieto, P.M, Martin-Lomas, M, Gimenez-Gallego, G, Jimenez-Barbero, J.
Deposit date:2005-10-25
Release date:2006-10-03
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:Solution NMR structure of a human FGF-1 monomer, activated by a hexasaccharide heparin-analogue.
Febs J., 273, 2006
2FGF
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THREE-DIMENSIONAL STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR, A STRUCTURAL HOMOLOG OF INTERLEUKIN 1BETA
Descriptor: HEPARIN-BINDING GROWTH FACTOR 2 PRECURSOR, SULFATE ION
Authors:Zhang, J, Sprang, S.R.
Deposit date:1991-02-19
Release date:1992-01-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1 beta.
Proc.Natl.Acad.Sci.USA, 88, 1991
1NZK
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Crystal Structure of a Multiple Mutant (L44F, L73V, V109L, L111I, C117V) of Human Acidic Fibroblast Growth Factor
Descriptor: Acidic Fibroblast Growth Factor, FORMIC ACID, SULFATE ION
Authors:Brych, S.R, Kim, J, Logan, T.M, Blaber, M.
Deposit date:2003-02-18
Release date:2004-03-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Accommodation of a highly symmetric core within a symmetric protein superfold.
Protein Sci., 12, 2003
1P63
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Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I)
Descriptor: ACIDIC FIBROBLAST GROWTH FACTOR, FORMIC ACID, SULFATE ION
Authors:Brych, S.R, Kim, J, Logan, T.M, Blaber, M.
Deposit date:2003-04-28
Release date:2004-05-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Accommodation of a highly symmetric core within a symmetric protein superfold
Protein Sci., 12, 2003
2HWA
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Crystal structure of Lys12Thr/Cys117Val mutant of human acidic fibroblast growth factor at 1.65 angstrom resolution.
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2006-08-01
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HW9
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Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution.
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2006-08-01
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HWM
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Crystal structure of Lys12Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.60 angstrom resolution
Descriptor: FORMIC ACID, Heparin-binding growth factor 1
Authors:Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2006-08-01
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
1PZZ
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Crystal structure of FGF-1, V51N mutant
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Kim, J, Blaber, M.
Deposit date:2003-07-14
Release date:2004-07-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
1Q03
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Crystal structure of FGF-1, S50G/V51G mutant
Descriptor: Heparin-binding growth factor 1
Authors:Kim, J, Blaber, M.
Deposit date:2003-07-15
Release date:2004-07-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
1Q04
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Crystal structure of FGF-1, S50E/V51N
Descriptor: FORMIC ACID, Heparin-binding growth factor 1
Authors:Kim, J, Blaber, M.
Deposit date:2003-07-15
Release date:2004-07-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
1PWA
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Crystal structure of Fibroblast Growth Factor 19
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fibroblast growth factor-19, GLYCEROL, ...
Authors:Harmer, N.J, Pellegrini, L, Chirgadze, D, Fernandez-Recio, J, Blundell, T.L.
Deposit date:2003-07-01
Release date:2004-01-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity.
Biochemistry, 43, 2004
2HZ9
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Crystal structure of Lys12Val/Asn95Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.70 angstrom resolution.
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2006-08-08
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions
J.Mol.Biol., 371, 2007
1Q1U
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Crystal structure of human FHF1b (FGF12b)
Descriptor: SULFATE ION, fibroblast growth factor homologous factor 1
Authors:Olsen, S.K, Garbi, M, Zampieri, N, Eliseenkova, A.V, Ornitz, D.M, Goldfarb, M, Mohammadi, M.
Deposit date:2003-07-22
Release date:2003-08-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs
J.Biol.Chem., 278, 2003
1QQL
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THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7/1 CHIMERA
Descriptor: FIBROBLAST GROWTH FACTOR 7/1 CHIMERA
Authors:Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L.
Deposit date:1999-06-07
Release date:2000-01-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
1QQK
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THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7 (KERATINOCYTE GROWTH FACTOR)
Descriptor: FIBROBLAST GROWTH FACTOR 7
Authors:Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L.
Deposit date:1999-06-07
Release date:2000-01-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
2J3P
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crystal structure of rat FGF1 at 1.4 A
Descriptor: HEPARIN-BINDING GROWTH FACTOR 1, SULFATE ION
Authors:Kulahin, N, Kristensen, O, Berezin, V, Gajhede, M, Bock, E.
Deposit date:2006-08-22
Release date:2007-02-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of Rat Acidic Fibroblast Growth Factor at 1.4 A Resolution.
Acta Crystallogr.,Sect.F, 63, 2007
2K43
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Acidic fibroblast growth factor solution structure in the FGF-1-C2A binary complex: key component in the fibroblast growthfactor non-classical pathway
Descriptor: Heparin-binding growth factor 1
Authors:Mohan, S.K, Yu, C.
Deposit date:2008-05-28
Release date:2009-06-02
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:FGF-1-C2A binary complex structure: key component in the acidic fibroblast growth factor release
To be Published

217705

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