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2QOO
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Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:Y742F triple mutant
Descriptor: Ephrin receptor
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOF
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Human EphA3 kinase and juxtamembrane region, Y596F mutant
Descriptor: BETA-MERCAPTOETHANOL, Ephrin receptor
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOD
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Human EphA3 kinase and juxtamembrane region, Y602F mutant
Descriptor: Ephrin receptor
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QON
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Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:Y742A triple mutant
Descriptor: Ephrin receptor, GLYCEROL
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-08-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QO9
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Human EphA3 kinase and juxtamembrane region, phosphorylated, AMP-PNP bound
Descriptor: Ephrin receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOK
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Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:S768A triple mutant
Descriptor: BETA-MERCAPTOETHANOL, Ephrin receptor
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOC
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Human EphA3 kinase domain, phosphorylated, AMP-PNP bound structure
Descriptor: BETA-MERCAPTOETHANOL, Ephrin receptor, MAGNESIUM ION, ...
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOQ
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Human EphA3 kinase and juxtamembrane region, base, AMP-PNP bound structure
Descriptor: Ephrin receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Loppnau, P, Allali-Hassani, A, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-10-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOL
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Human EphA3 kinase and juxtamembrane region, Y596:Y602:S768G triple mutant
Descriptor: Ephrin receptor
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QO7
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Human EphA3 kinase and juxtamembrane region, dephosphorylated, AMP-PNP bound
Descriptor: BETA-MERCAPTOETHANOL, Ephrin receptor, GLYCEROL, ...
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-08-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.605 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOI
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BU of 2qoi by Molmil
Human EphA3 kinase and juxtamembrane region, Y596F:Y602F double mutant
Descriptor: BETA-MERCAPTOETHANOL, Ephrin receptor
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2JW2
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BU of 2jw2 by Molmil
Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
Descriptor: StAR-related lipid transfer protein 13
Authors:Li, H, Sze, K, Fung, K.
Deposit date:2007-10-03
Release date:2008-10-21
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
To be Published
3BQ7
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BU of 3bq7 by Molmil
SAM domain of Diacylglycerol Kinase delta1 (E35G)
Descriptor: Diacylglycerol kinase delta
Authors:Knight, M.J, Bowie, J.U, Sawaya, M.R.
Deposit date:2007-12-19
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Regulation of Enzyme Localization by Polymerization: Polymer Formation by the SAM Domain of Diacylglycerol Kinase delta1
Structure, 16, 2008
3BS7
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BU of 3bs7 by Molmil
Crystal structure of the Sterile Alpha Motif (SAM) domain of Hyphen/Aveugle
Descriptor: Protein aveugle
Authors:Rajakulendran, T, Sicheri, F.
Deposit date:2007-12-22
Release date:2008-02-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.
Proc.Natl.Acad.Sci.USA, 105, 2008
3BS5
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BU of 3bs5 by Molmil
Crystal Structure of hCNK2-SAM/dHYP-SAM Complex
Descriptor: Connector enhancer of kinase suppressor of ras 2, Protein aveugle
Authors:Rajakulendran, T, Ceccarelli, D.F, Kurinov, I, Sicheri, F.
Deposit date:2007-12-22
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.
Proc.Natl.Acad.Sci.USA, 105, 2008
2K60
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BU of 2k60 by Molmil
NMR structure of calcium-loaded STIM1 EF-SAM
Descriptor: CALCIUM ION, PROTEIN (Stromal interaction molecule 1)
Authors:Stathopulos, P.B, Ikura, M.
Deposit date:2008-07-02
Release date:2008-10-07
Last modified:2013-07-24
Method:SOLUTION NMR
Cite:Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry.
Cell(Cambridge,Mass.), 135, 2008
3DZQ
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BU of 3dzq by Molmil
Human EphA3 kinase domain in complex with inhibitor AWL-II-38.3
Descriptor: EPH receptor A3, N-[2-methyl-5-({[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]carbonyl}amino)phenyl]isoxazole-5-carboxamide
Authors:Walker, J.R, Syeda, F, Gray, N, Mansoor, W, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2008-07-30
Release date:2008-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Kinase Domain of Human Ephrin Type-A Receptor 3 (Epha3) in Complex with ALW-II-38-3.
To be Published
2KAP
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BU of 2kap by Molmil
Solution structure of DLC1-SAM
Descriptor: Rho GTPase-activating protein 7
Authors:Yang, S, Yang, D.
Deposit date:2008-11-12
Release date:2009-10-20
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Characterization of DLC1-SAM equilibrium unfolding at the amino acid residue level
Biochemistry, 48, 2009
3FY2
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Human EphA3 Kinase and Juxtamembrane Region Bound to Substrate KQWDNYEFIW
Descriptor: Ephrin type-A receptor 3, peptide substrate
Authors:Davis, T, Walker, J.R, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2009-01-21
Release date:2009-02-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases.
Febs J., 276, 2009
3FXX
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BU of 3fxx by Molmil
Human EphA3 Kinase and Juxtamembrane Region Bound to Substrate KQWDNYE[pTyr]IW
Descriptor: Ephrin type-A receptor 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Davis, T, Walker, J.R, Mackenzie, F, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2009-01-21
Release date:2009-02-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases.
Febs J., 276, 2009
2KG5
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BU of 2kg5 by Molmil
NMR Solution structure of ARAP3-SAM
Descriptor: Arf-GAP, Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Authors:Leone, M, Pellecchia, M.
Deposit date:2009-03-05
Release date:2009-11-17
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:The Sam domain of the lipid phosphatase Ship2 adopts a common model to interact with Arap3-Sam and EphA2-Sam.
Bmc Struct.Biol., 9, 2009
3H8M
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SAM domain of human ephrin type-a receptor 7 (EPHA7)
Descriptor: Ephrin type-A receptor 7
Authors:Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2009-04-29
Release date:2009-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:SAM Domain of Human Ephrin Type-A Receptor 7 (Epha7)
To be Published
2L5Y
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BU of 2l5y by Molmil
NMR structure of calcium-loaded STIM2 EF-SAM.
Descriptor: CALCIUM ION, Stromal interaction molecule 2
Authors:Zheng, L, Stathopulos, P.B, Ikura, M.
Deposit date:2010-11-09
Release date:2011-01-19
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry.
Proc.Natl.Acad.Sci.USA, 108, 2011
2Y9U
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Structural basis of p63a SAM domain mutants involved in AEC syndrome
Descriptor: SULFATE ION, TUMOR PROTEIN 63
Authors:Sathyamurthy, A, Freund, S.M.V, Johnson, C.M, Allen, M.D.
Deposit date:2011-02-16
Release date:2011-08-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis of P63Alpha Sam Domain Mutants Involved in Aec Syndrome.
FEBS J., 278, 2011
2Y9T
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Structural basis of p63a SAM domain mutants involved in AEC syndrome
Descriptor: TUMOR PROTEIN 63
Authors:Sathyamurthy, A, Freund, S.M.V, Johnson, C.M, Allen, M.D.
Deposit date:2011-02-16
Release date:2011-08-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis of P63Alpha Sam Domain Mutants Involved in Aec Syndrome.
FEBS J., 278, 2011

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