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6DN5	SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) cyclic peptide inhibitor Descriptor: SPRY domain-containing SOCS box protein 2, SULFATE ION, WDINNN(BAL) cyclic peptide inhibitor Authors: Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S. Deposit date: 2018-06-06 Release date: 2019-04-17 Last modified: 2020-01-08 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent. ACS Chem. Biol., 13, 2018
6DN8	SPRY domain-containing SOCS box protein 2 complexed with (GZJ)VDINNN(CY3) Cyclic peptide inhibitor Descriptor: (GZJ)VDINNN(CY3) Cyclic peptide inhibitor, ACETATE ION, SPRY domain-containing SOCS box protein 4, ... Authors: Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S. Deposit date: 2018-06-06 Release date: 2019-04-17 Last modified: 2022-04-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent. ACS Chem. Biol., 13, 2018
7QRZ	Crystal structure of B30.2 PRYSPRY domain of MID2 Descriptor: 1,2-ETHANEDIOL, Probable E3 ubiquitin-protein ligase MID2, SULFATE ION Authors: Chaikuad, A, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2022-01-12 Release date: 2022-05-04 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Crystal structure of B30.2 PRYSPRY domain of MID2 To Be Published
7QRY	Crystal structure of B30.2 PRYSPRY domain of MID1 Descriptor: E3 ubiquitin-protein ligase Midline-1 Authors: Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2022-01-12 Release date: 2022-05-04 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Crystal structure of B30.2 PRYSPRY domain of MID1 To Be Published
7QS5	Crystal structure of B30.2 PRYSPRY domain of TRIM67 Descriptor: 1,2-ETHANEDIOL, Tripartite motif-containing protein 67 Authors: Chaikuad, A, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2022-01-12 Release date: 2022-05-04 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of B30.2 PRYSPRY domain of TRIM67 To Be Published
5JI7	The Crystal Structure Of IUS-SPRY Domain From RanBPM/9 Descriptor: Ran-binding protein 9 Authors: Hong, S.K, Kim, K.-H, Kim, E.E. Deposit date: 2016-04-22 Release date: 2016-11-09 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development. J.Mol.Biol., 428, 2016
5JI9	The Crystal Structure Of IUS-SPRY Domain From RanBPM/9 Descriptor: Ran-binding protein 9 Authors: Hong, S.K, Kim, K.-H, Kim, E.E. Deposit date: 2016-04-22 Release date: 2016-11-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development. J.Mol.Biol., 428, 2016
5JIU	The crystal structure of RanBPM/9 IUS-SPRY domain in complex with DDX-4 peptide Descriptor: CHLORIDE ION, Probable ATP-dependent RNA helicase DDX4, Ran-binding protein 9 Authors: Hong, S.K, Kim, K.-H, Kim, E.E. Deposit date: 2016-04-22 Release date: 2016-11-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.054 Å) Cite: Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development. J.Mol.Biol., 428, 2016
5JIA	The Crystal Structure Of IUS-SPRY Domain From RanBP10 Descriptor: IMIDAZOLE, Ran-binding protein 10 Authors: Hong, S.K, Kim, K.-H, Kim, E.E. Deposit date: 2016-04-22 Release date: 2016-11-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development. J.Mol.Biol., 428, 2016
6J6L	Crystal structure of mouse Ryanodine Receptor 2 SPRY1 Domain (650-844) disease mutant I784F Descriptor: ISOPROPYL ALCOHOL, Ryanodine receptor 2 Authors: Ma, R, Lin, L, Yuchi, Z. Deposit date: 2019-01-15 Release date: 2020-01-15 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.452 Å) Cite: A SPRY1 domain cardiac ryanodine receptor variant associated with short-coupled torsade de pointes. Sci Rep, 11, 2021
6JKJ	Crystal structure of human SPSB2 in the apo-state Descriptor: SPRY domain-containing SOCS box protein 2 Authors: Luo, Y, Kuang, Z. Deposit date: 2019-03-01 Release date: 2019-07-03 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of the SPRY domain of human SPSB2 in the apo state. Acta Crystallogr.,Sect.F, 75, 2019
6JWN	Crystal structure of the SPRY domain of SPSB2 in complex with cR9, a cyclic peptide inhibitor of SPSB-iNOS interaction Descriptor: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2 Authors: Li, K, Kuang, Z. Deposit date: 2019-04-21 Release date: 2020-04-22 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Crystal structure of SPSB2 in complex with cR9, a cyclic peptide inhibitor of SPSB-iNOS interaction To Be Published
6KIM	Crystal structure of diamondback moth ryanodine receptor SPRY2 domain Descriptor: GLYCEROL, Ryanodine receptor Authors: Zhou, Y, Lin, L, Yuchi, Z. Deposit date: 2019-07-19 Release date: 2020-07-22 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.057 Å) Cite: Crystal structure of diamondback moth ryanodine receptor SPRY2 domain To Be Published
6JWM	Crystal structure of the SPRY domain of SPSB2 in complex with cR7, a potent cyclic peptide inhibitor of SPSB2-iNOS interaction Descriptor: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2 Authors: Li, K, Kuang, Z. Deposit date: 2019-04-21 Release date: 2020-04-22 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.23 Å) Cite: Crystal structure of SPSB2 in complex with cR7, a potent cyclic peptide inhibitor of SPSB2-iNOS interaction To Be Published
6KEY	Structural basis for the regulation of inducible nitric oxide synthase (iNOS) by the SPRY domain-containing SOCS box protein 2 (SPSB2) Descriptor: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2 Authors: Li, K, Kuang, Z. Deposit date: 2019-07-05 Release date: 2020-07-01 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.24 Å) Cite: Structural basis for the regulation of inducible nitric oxide synthase by the SPRY domain-containing SOCS box protein SPSB2, an E3 ubiquitin ligase. Nitric Oxide, 113-114, 2021
6LT9	The crystal structure of diamondback moth ryanodine receptor SPRY1 domain Descriptor: GLYCEROL, Ryanodine receptor 1, SODIUM ION Authors: Zhou, Y, Lin, L, Yuchi, Z. Deposit date: 2020-01-22 Release date: 2021-01-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.801 Å) Cite: The crystal structure of diamondback moth ryanodine receptor SPRY1 domain To Be Published
5VSN	Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080-1253) disease mutant P1124L Descriptor: GLYCEROL, POTASSIUM ION, Ryanodine receptor 2 Authors: Yuchi, Z, Van Petegem, F. Deposit date: 2017-05-12 Release date: 2018-05-23 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.439 Å) Cite: Cardiac hypertrophy and arrhythmia in mice induced by a mutation in ryanodine receptor 2. JCI Insight, 5, 2019
4UWE	Structure of the ryanodine receptor at resolution of 8.5 A in partially open state Descriptor: RYANODINE RECEPTOR 1 Authors: Efremov, R.G, Leitner, A, Aebersold, R, Raunser, S. Deposit date: 2014-08-11 Release date: 2014-12-10 Last modified: 2017-08-30 Method: ELECTRON MICROSCOPY (8.5 Å) Cite: Architecture and Conformational Switch Mechanism of the Ryanodine Receptor. Nature, 517, 2015
4V1P	BTN3 Structure Descriptor: BUTYROPHILIN SUBFAMILY 3 MEMBER A1 Authors: James, L.C. Deposit date: 2014-09-30 Release date: 2015-07-22 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Activation of Human Gammadelta T Cells by Cytosolic Interactions of Btn3A1 with Soluble Phosphoantigens and the Cytoskeletal Adaptor Periplakin. J.Immunol., 194, 2015
5LYG	CRYSTAL STRUCTURE OF INTRACELLULAR B30.2 DOMAIN OF BTN3A1 BOUND TO MALONATE Descriptor: 1,2-ETHANEDIOL, Butyrophilin subfamily 3 member A1, MALONATE ION Authors: Mohammed, F, Baker, A.T, Salim, M, Willcox, B.E. Deposit date: 2016-09-28 Release date: 2017-09-13 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (1.6 Å) Cite: BTN3A1 Discriminates gamma delta T Cell Phosphoantigens from Nonantigenic Small Molecules via a Conformational Sensor in Its B30.2 Domain. ACS Chem. Biol., 12, 2017
5LYK	CRYSTAL STRUCTURE OF INTRACELLULAR B30.2 DOMAIN OF BTN3A1 BOUND TO CITRATE Descriptor: 1,2-ETHANEDIOL, Butyrophilin subfamily 3 member A1, CITRATE ANION Authors: Mohammed, F, Baker, A.T, Salim, M, Willcox, B.E. Deposit date: 2016-09-28 Release date: 2017-09-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: BTN3A1 Discriminates gamma delta T Cell Phosphoantigens from Nonantigenic Small Molecules via a Conformational Sensor in Its B30.2 Domain. ACS Chem. Biol., 12, 2017
4UWA	Structure of the ryanodine receptor at resolution of 6.1 A in closed state Descriptor: RYANODINE RECEPTOR 1 Authors: Efremov, R.G, Leitner, A, Aebersold, R, Raunser, S. Deposit date: 2014-08-11 Release date: 2014-12-10 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (6.1 Å) Cite: Architecture and Conformational Switch Mechanism of the Ryanodine Receptor. Nature, 517, 2015
3KB5	PRY-SPRY domain of human TRIM72 Descriptor: Tripartite motif-containing protein 72 Authors: Park, E.Y, Kwon, O.-B, Jeong, B.-C, Song, H.K. Deposit date: 2009-10-20 Release date: 2009-12-22 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of PRY-SPRY domain of human TRIM72 Proteins, 2009
5ZZ3	Crystal structure of intracellular B30.2 domain of BTN3A3 Descriptor: Butyrophilin, subfamily 3, member A3 isoform b variant Authors: Yang, Y.Y, Li, X, Liu, W.D, Chen, C.C, Guo, R.T, Zhang, Y.H. Deposit date: 2018-05-30 Release date: 2019-04-03 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3 Å) Cite: A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation. Immunity, 50, 2019
6SWY	Structure of active GID E3 ubiquitin ligase complex minus Gid2 and delta Gid9 RING domain Descriptor: Glucose-induced degradation protein 8, Protein FYV10,Protein FYV10,Protein FYV10,Protein FYV10,Protein FYV10,Protein FYV10,Protein FYV10, Vacuolar import and degradation protein 24, ... Authors: Qiao, S, Prabu, J.R, Schulman, B.A. Deposit date: 2019-09-24 Release date: 2019-11-20 Last modified: 2022-07-20 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly Mol.Cell, 77, 2020

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