2VYI
 
 | | Crystal Structure of the TPR domain of Human SGT | | Descriptor: | SGTA PROTEIN | | Authors: | Dutta, S, Tan, Y.J. | | Deposit date: | 2008-07-24 | | Release date: | 2008-08-12 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and Functional Characterization of Human Sgt and its Interaction with Vpu of the Human Immunodeficiency Virus Type 1.
Biochemistry, 47, 2008
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7AI4
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7AIE
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5G05
 | | Cryo-EM structure of combined apo phosphorylated APC | | Descriptor: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | | Authors: | Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. | | Deposit date: | 2016-03-16 | | Release date: | 2016-05-25 | | Last modified: | 2019-09-11 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation.
Nature, 533, 2016
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5FJY
 | | Crystal structure of mouse kinesin light chain 2 (residues 161-480) | | Descriptor: | KINESIN LIGHT CHAIN 2, UNKNOWN PEPTIDE | | Authors: | Pernigo, S, Yip, Y.Y, Sanger, A, Xu, M, Dodding, M.P, Steiner, R.A. | | Deposit date: | 2015-10-14 | | Release date: | 2016-02-24 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | The Light Chains of Kinesin-1 are Autoinhibited.
Proc.Natl.Acad.Sci.USA, 113, 2016
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7DHG
 | | Crystal structure of SARS-CoV-2 Orf9b complex with human TOM70 | | Descriptor: | Mitochondrial import receptor subunit TOM70, ORF9b protein | | Authors: | Gao, X, Zhu, K, Qin, B, Olieric, V, Wang, M, Cui, S. | | Deposit date: | 2020-11-14 | | Release date: | 2021-05-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions.
Nat Commun, 12, 2021
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4GCN
 | | N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans | | Descriptor: | Protein STI-1, TRIETHYLENE GLYCOL | | Authors: | Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2012-07-30 | | Release date: | 2012-08-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
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2GW1
 | | Crystal Structure of the Yeast Tom70 | | Descriptor: | Mitochondrial precursor proteins import receptor | | Authors: | Wu, Y, Sha, B. | | Deposit date: | 2006-05-03 | | Release date: | 2006-06-27 | | Last modified: | 2018-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of yeast mitochondrial outer membrane translocon member Tom70p.
Nat.Struct.Mol.Biol., 13, 2006
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7NTF
 | | Cryo-EM structure of unliganded O-GlcNAc transferase | | Descriptor: | Isoform 1 of UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | | Authors: | Meek, R.W, Blaza, J.N, Davies, G.J. | | Deposit date: | 2021-03-09 | | Release date: | 2021-11-17 | | Last modified: | 2021-11-24 | | Method: | ELECTRON MICROSCOPY (5.32 Å) | | Cite: | Cryo-EM structure provides insights into the dimer arrangement of the O-linked beta-N-acetylglucosamine transferase OGT.
Nat Commun, 12, 2021
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6TNT
 | | SUMOylated apoAPC/C with repositioned APC2 WHB domain | | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | | Authors: | Barford, D, Yatskevich, S. | | Deposit date: | 2019-12-10 | | Release date: | 2021-01-13 | | Last modified: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation.
Cell Rep, 34, 2021
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2NC9
 | | Apo solution structure of Hop TPR2A | | Descriptor: | Stress-induced-phosphoprotein 1 | | Authors: | Darby, J.F, Vidler, L.R, Simpson, P.J, Matthews, S.J, Sharp, S.Y, Pearl, L.H, Hoelder, S, Workman, P. | | Deposit date: | 2016-03-23 | | Release date: | 2017-03-29 | | Last modified: | 2020-10-28 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches.
Sci Rep, 10, 2020
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7Y4I
 | | Crystal structure of SPINDLY in complex with GDP | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY | | Authors: | Xu, S.T, Wan, L.H. | | Deposit date: | 2022-06-14 | | Release date: | 2022-12-07 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structural insights into mechanism and specificity of the plant protein O-fucosyltransferase SPINDLY.
Nat Commun, 13, 2022
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3VTY
 | | Crystal structure of MamA | | Descriptor: | CHLORIDE ION, MamA | | Authors: | Zeytuni, N, Baran, D, Davidov, G, Zarivach, R. | | Deposit date: | 2012-06-08 | | Release date: | 2012-10-31 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA
J.Struct.Biol., 180, 2012
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3VTX
 | | Crystal structure of MamA protein | | Descriptor: | GLYCEROL, MamA | | Authors: | Zeytuni, N, Baran, D, Davidov, G, Zarivach, R. | | Deposit date: | 2012-06-08 | | Release date: | 2012-10-31 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA
J.Struct.Biol., 180, 2012
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7YEH
 | | Cryo-EM structure of human OGT-OGA complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein O-GlcNAcase, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ... | | Authors: | Lu, P, Liu, Y, Yu, H, Gao, H. | | Deposit date: | 2022-07-05 | | Release date: | 2023-07-12 | | Last modified: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.92 Å) | | Cite: | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex.
Nat Commun, 14, 2023
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7YEA
 | | Human O-GlcNAc transferase Dimer | | Descriptor: | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | | Authors: | Gao, H, Lu, P, Liu, Y. | | Deposit date: | 2022-07-05 | | Release date: | 2023-07-12 | | Last modified: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.82 Å) | | Cite: | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex.
Nat Commun, 14, 2023
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8A61
 | | S. cerevisiae apo phosphorylated APC/C | | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... | | Authors: | Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J. | | Deposit date: | 2022-06-16 | | Release date: | 2022-08-31 | | Method: | ELECTRON MICROSCOPY (5.4 Å) | | Cite: | Cryo-EM structure of the S. cerevisiae apo phosphorylated APC/C
To Be Published
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3ZFW
 | | Crystal structure of the TPR domain of kinesin light chain 2 in complex with a tryptophan-acidic cargo peptide | | Descriptor: | KINESIN LIGHT CHAIN 2, PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 | | Authors: | Pernigo, S, Lamprecht, A, Steiner, R.A, Dodding, M.P. | | Deposit date: | 2012-12-12 | | Release date: | 2013-04-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural Basis for Kinesin-1:Cargo Recognition.
Science, 340, 2013
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6EJN
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6EOU
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6FO1
 | | Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RNA polymerase II-associated protein 3, RuvB-like 1, ... | | Authors: | Martino, F, Munoz-Hernandez, H, Rodriguez, C.F, Pearl, L.H, Llorca, O. | | Deposit date: | 2018-02-05 | | Release date: | 2018-04-04 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.57 Å) | | Cite: | RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex.
Nat Commun, 9, 2018
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6FUZ
 | | Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of JIP1 | | Descriptor: | GLYCEROL, Kinesin light chain 1,Kinesin light chain 1,C-Jun-amino-terminal kinase-interacting protein 1, nanobody | | Authors: | Pernigo, S, Dodding, M.P, Steiner, R.A. | | Deposit date: | 2018-02-28 | | Release date: | 2018-05-02 | | Last modified: | 2019-09-18 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors.
Elife, 7, 2018
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6FV0
 | | Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of torsinA | | Descriptor: | DI(HYDROXYETHYL)ETHER, Kinesin light chain 1,Torsin-1A, nanobody | | Authors: | Pernigo, S, Dodding, M.P, Steiner, R.A. | | Deposit date: | 2018-02-28 | | Release date: | 2018-03-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors.
Elife, 7, 2018
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5OJ8
 | | Crystal structure of the KLC1-TPR domain ([A1-B5] fragment) | | Descriptor: | Kinesin light chain 1, PHOSPHATE ION | | Authors: | Nguyen, T.Q, Chenon, M, Vilela, F, Velours, C, Fernandez-Varela, P, Llinas, P, Menetrey, J. | | Deposit date: | 2017-07-20 | | Release date: | 2017-10-11 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.247 Å) | | Cite: | Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain.
PLoS ONE, 12, 2017
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3CVQ
 | | Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to PTS1 peptide (7-SKL) | | Descriptor: | GLYCEROL, PTS1 peptide 7-SKL (Ac-SNRWSKL), Peroxisome targeting signal 1 receptor PEX5 | | Authors: | Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J. | | Deposit date: | 2008-04-18 | | Release date: | 2008-06-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
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