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5XJG
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BU of 5xjg by Molmil
Crystal structure of Vac8p bound to Nvj1p
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Nucleus-vacuole junction protein 1, ...
Authors:Jeong, H, Park, J, Jun, Y, Lee, C.
Deposit date:2017-05-01
Release date:2017-06-07
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanistic insight into the nucleus-vacuole junction based on the Vac8p-Nvj1p crystal structure.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8Y0G
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BU of 8y0g by Molmil
Human beta-catenin crystal structure
Descriptor: Catenin beta-1
Authors:Tim, F.
Deposit date:2024-01-22
Release date:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal protein of human Beta-catenin
To Be Published
8Y14
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BU of 8y14 by Molmil
Beta-catenin Crystal Structure
Descriptor: Catenin beta-1
Authors:Tim, F.
Deposit date:2024-01-23
Release date:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Beta-catenin Crystal Structure
To Be Published
4DJS
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BU of 4djs by Molmil
Structure of beta-catenin in complex with a stapled peptide inhibitor
Descriptor: Catenin beta-1, stapled peptide RRWPQ(MK8)ILD(MK8)HVRRVWR
Authors:Bowman, B.R, Grossmann, T.N, Yeh, J.T.-H, Verdine, G.L.
Deposit date:2012-02-02
Release date:2012-10-17
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.029 Å)
Cite:Inhibition of oncogenic Wnt signaling through direct targeting of beta-catenin.
Proc.Natl.Acad.Sci.USA, 109, 2012
4EV8
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BU of 4ev8 by Molmil
Crystal structure of mouse catenin beta-59 in 2.4M urea.
Descriptor: Catenin beta-1, UREA
Authors:Wang, C, Zhang, G.Y.
Deposit date:2012-04-26
Release date:2013-05-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of mouse catenin beta-59 in 2.4M urea.
TO BE PUBLISHED
4EVA
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BU of 4eva by Molmil
Crystal Structure of Mouse Catenin beta-59 in 5.6M urea
Descriptor: Catenin beta-1, UREA
Authors:Wang, C, Zhang, G.Y.
Deposit date:2012-04-26
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Crystal Structure of Mouse Catenin beta-59 in 5.6M urea
TO BE PUBLISHED
4R11
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BU of 4r11 by Molmil
A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo
Descriptor: Cadherin-related hmr-1, IODIDE ION, Protein humpback-2
Authors:Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I.
Deposit date:2014-08-03
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
4R0Z
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BU of 4r0z by Molmil
A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo
Descriptor: FORMIC ACID, Protein humpback-2
Authors:Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I.
Deposit date:2014-08-03
Release date:2015-04-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
4R10
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BU of 4r10 by Molmil
A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo
Descriptor: 1,2-ETHANEDIOL, Cadherin-related hmr-1, Protein humpback-2, ...
Authors:Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I.
Deposit date:2014-08-03
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
3SLA
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BU of 3sla by Molmil
X-ray structure of first four repeats of human beta-catenin
Descriptor: Catenin beta-1, GLYCEROL, SODIUM ION
Authors:Gupta, D, Bienz, M.
Deposit date:2011-06-24
Release date:2012-02-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
3TT9
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BU of 3tt9 by Molmil
Crystal structure of the stable degradation fragment of human plakophilin 2 isoform a (PKP2a) C752R variant
Descriptor: GLYCEROL, Plakophilin-2
Authors:Schuetz, A, Roske, Y, Gerull, B, Heinemann, U.
Deposit date:2011-09-14
Release date:2012-08-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations.
Circ Cardiovasc Genet, 5, 2012
7N9H
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BU of 7n9h by Molmil
Structure of the mammalian importin a1 bound to the TDP-43 NLS
Descriptor: Importin subunit alpha-1, TAR DNA-binding protein 43
Authors:Doll, S.G, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta.
Cell Rep, 39, 2022
6P6E
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BU of 6p6e by Molmil
Structure of Mouse Importin alpha - PAC3 NLS peptide complex
Descriptor: Importin subunit alpha-1, PAC3 NLS
Authors:Bernardes, N.E, Silva, T.D, Fukuda, C.A, Oliveira, H.C, Fontes, M.R.M.
Deposit date:2019-06-03
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Comparative study of the interactions between fungal transcription factor nuclear localization sequences with mammalian and fungal importin-alpha.
Sci Rep, 10, 2020
6P6A
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BU of 6p6a by Molmil
Structure of Mouse Importin alpha - NIT2 NLS peptide complex
Descriptor: Importin subunit alpha-1, Nitrogen catabolic enzyme regulatory protein
Authors:Bernardes, N.E, Fukuda, C.A, Silva, T.D, Oliveira, H.C, Fontes, M.R.M.
Deposit date:2019-06-03
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Comparative study of the interactions between fungal transcription factor nuclear localization sequences with mammalian and fungal importin-alpha.
Sci Rep, 10, 2020
1BK6
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BU of 1bk6 by Molmil
KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS
Descriptor: KARYOPHERIN ALPHA, LARGE T ANTIGEN
Authors:Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
Deposit date:1998-07-14
Release date:1999-01-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
1BK5
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BU of 1bk5 by Molmil
KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE
Descriptor: COBALT (II) ION, KARYOPHERIN ALPHA
Authors:Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
Deposit date:1998-07-14
Release date:1999-01-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
2GL7
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BU of 2gl7 by Molmil
Crystal Structure of a beta-catenin/BCL9/Tcf4 complex
Descriptor: B-cell lymphoma 9 protein, Beta-catenin, Transcription factor 7-like 2
Authors:Sampietro, J.
Deposit date:2006-04-04
Release date:2006-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of a beta-Catenin/BCL9/Tcf4 Complex.
Mol.Cell, 24, 2006
2JDQ
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BU of 2jdq by Molmil
C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5
Descriptor: IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC PROTEIN 2
Authors:Tarendeau, F, Guilligay, D, Mas, P, Boulo, S, Baudin, F, Ruigrok, R.W.H, Hart, D.J, Cusack, S.
Deposit date:2007-01-11
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Nuclear Import Function of the C- Terminal Domain of Influenza Virus Polymerase Pb2 Subunit
Nat.Struct.Mol.Biol., 14, 2007
5K9S
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BU of 5k9s by Molmil
Importin-alpha in complex with HNF1-beta peptide
Descriptor: HNF1 beta A splice variant 2, Importin subunit alpha-1
Authors:Wiedmann, M.M, Aibara, S, Spring, D.R, Stewart, M, Brenton, J.
Deposit date:2016-06-01
Release date:2016-11-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Importin-alpha in complex with HNF1-beta peptide
To Be Published
5KLT
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BU of 5klt by Molmil
Prototypical P4[M]cNLS
Descriptor: Importin subunit alpha-1, Prototypical P4[M]cNLS
Authors:Smith, K.M, Forwood, J.K.
Deposit date:2016-06-25
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting.
Biochim Biophys Acta Mol Cell Res, 1865, 2018
5KLR
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BU of 5klr by Molmil
Prototypical P4[R]cNLS
Descriptor: Importin subunit alpha-1, Prototypical P4[R]cNLS
Authors:Smith, K.M, Forwood, J.K.
Deposit date:2016-06-25
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting.
Biochim Biophys Acta Mol Cell Res, 1865, 2018
4MZ5
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BU of 4mz5 by Molmil
Structure of importin-alpha: dUTPase NLS complex
Descriptor: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1
Authors:Marfori, M, Rona, G, Vertessy, B.G, Kobe, B.
Deposit date:2013-09-29
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.
Acta Crystallogr.,Sect.D, 69, 2013
4MZ6
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BU of 4mz6 by Molmil
Structure of importin-alpha: dUTPase S11E NLS mutant complex
Descriptor: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1
Authors:Marfori, M, Rona, G, Vertessy, B.G, Kobe, B.
Deposit date:2013-09-29
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.
Acta Crystallogr.,Sect.D, 69, 2013
2C1T
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BU of 2c1t by Molmil
Structure of the Kap60p:Nup2 complex
Descriptor: IMPORTIN ALPHA SUBUNIT, NUCLEOPORIN NUP2
Authors:Matsuura, Y, Stewart, M.
Deposit date:2005-09-20
Release date:2005-11-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Nup50/Npap60 Function in Nuclear Import Complex Disassembly and Importin Recycling
Embo J., 24, 2005
2C1M
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BU of 2c1m by Molmil
Nup50:importin-alpha complex
Descriptor: IMPORTIN-ALPHA2 SUBUNIT, NUCLEOPORIN 50 KDA
Authors:Matsuura, Y, Stewart, M.
Deposit date:2005-09-16
Release date:2005-11-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Nup50/Npap60 Function in Nuclear Protein Import Complex Disassembly and Importin Recycling.
Embo J., 24, 2005

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PDB entries from 2024-03-27

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