3HN8
| Crystal structure of synaptotagmin | Descriptor: | CALCIUM ION, Synaptotagmin-3, ZINC ION | Authors: | Strop, P, Vrljic, M, Ernst, J, Brunger, A.T. | Deposit date: | 2009-05-30 | Release date: | 2010-02-23 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion. Nat.Struct.Mol.Biol., 17, 2010
|
|
3TWY
| RAT PKC C2 DOMAIN BOUND TO PB | Descriptor: | LEAD (II) ION, Protein kinase C alpha type, SULFATE ION | Authors: | Li, P. | Deposit date: | 2011-09-22 | Release date: | 2011-11-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Pb2+ as Modulator of Protein-Membrane Interactions. J.Am.Chem.Soc., 133, 2011
|
|
2Z0U
| Crystal structure of C2 domain of KIBRA protein | Descriptor: | WW domain-containing protein 1 | Authors: | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-05-07 | Release date: | 2008-05-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of C2 domain of KIBRA protein To be Published
|
|
2YOA
| Synaptotagmin-1 C2B domain with phosphoserine | Descriptor: | CALCIUM ION, PHOSPHOSERINE, SYNAPTOTAGMIN-1, ... | Authors: | Honigmann, A, van den Bogaart, G, Iraheta, E, Risselada, H.J, Milovanovic, D, Mueller, V, Muellar, S, Diederichsen, U, Fasshauer, D, Grubmuller, H, Hell, S.W, Eggeling, C, Kuhnel, K, Jahn, R. | Deposit date: | 2012-10-22 | Release date: | 2013-03-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Phosphatidylinositol 4,5-Bisphosphate Clusters Act as Molecular Beacons for Vesicle Recruitment Nat.Struct.Mol.Biol., 20, 2013
|
|
3W56
| Structure of a C2 domain | Descriptor: | C2 domain protein | Authors: | Traore, D.A.K, Whisstock, J.C. | Deposit date: | 2013-01-24 | Release date: | 2013-10-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Defining the interaction of perforin with calcium and the phospholipid membrane. Biochem.J., 456, 2013
|
|
3L9B
| Crystal Structure of Rat Otoferlin C2A | Descriptor: | MAGNESIUM ION, Otoferlin | Authors: | Helfmann, S, Neumann, P. | Deposit date: | 2010-01-04 | Release date: | 2011-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The crystal structure of the C2A domain of otoferlin reveals an unconventional top loop region. J.Mol.Biol., 406, 2011
|
|
3W57
| Structure of a C2 domain | Descriptor: | C2 domain protein, CALCIUM ION | Authors: | Traore, D.A.K, Whisstock, J.C. | Deposit date: | 2013-01-24 | Release date: | 2013-10-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.662 Å) | Cite: | Defining the interaction of perforin with calcium and the phospholipid membrane. Biochem.J., 456, 2013
|
|
5H4Z
| Crystal structure of S202G mutant of human SYT-5 C2A domain | Descriptor: | CALCIUM ION, CHLORIDE ION, Synaptotagmin-5 | Authors: | Qiu, X, Ge, J, Yan, X, Gao, Y, Teng, M, Niu, L. | Deposit date: | 2016-11-02 | Release date: | 2016-11-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain Int. J. Biol. Macromol., 95, 2017
|
|
5H4Y
| Crystal structure of human synaptotagmin 5 C2A domain | Descriptor: | ACETATE ION, CALCIUM ION, Synaptotagmin-5 | Authors: | Qiu, X, Gao, Y, Teng, M, Niu, L. | Deposit date: | 2016-11-02 | Release date: | 2016-11-30 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain Int. J. Biol. Macromol., 95, 2017
|
|
5LO8
| |
5LOB
| |
5LOW
| |
8FAF
| Unedited Octopus bimaculoides Synaptotagmin 1 C2A at room temperature | Descriptor: | Synaptotagmin | Authors: | McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.C, Sutton, R.B. | Deposit date: | 2022-11-26 | Release date: | 2023-07-19 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Temperature-dependent RNA editing in octopus extensively recodes the neural proteome. Cell, 186, 2023
|
|
8FAM
| Edited Octopus bimaculoides Synaptotagmin 1 C2A (I248V) at room temperature | Descriptor: | Synaptotagmin | Authors: | McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.J, Sutton, R.B. | Deposit date: | 2022-11-28 | Release date: | 2023-07-19 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Temperature-dependent RNA editing in octopus extensively recodes the neural proteome. Cell, 186, 2023
|
|
6TZ3
| Crystal Structure of Human Synaptotagmin 1 C2B without Ca2+ | Descriptor: | SULFATE ION, Synaptotagmin-1 | Authors: | Dominguez, M.J, Karmakar, S, Meyer, A.G, Sutton, R.B. | Deposit date: | 2019-08-09 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107, 2020
|
|
6U41
| 1.7 angstrom structure of a pathogenic human Syt 1 C2B (D304G) | Descriptor: | SULFATE ION, Synaptotagmin-1 | Authors: | Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. | Deposit date: | 2019-08-22 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107, 2020
|
|
6U4U
| 1.3 A structure of a pathogenic human Syt 1 C2B (I368T) | Descriptor: | SULFATE ION, Synaptotagmin-1 | Authors: | Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. | Deposit date: | 2019-08-26 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107, 2020
|
|
5YQ3
| |
6U4W
| 1.4 A structure of a pathogenic human Syt 1 C2B (D366E) | Descriptor: | SULFATE ION, Synaptotagmin-1 | Authors: | Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. | Deposit date: | 2019-08-26 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107, 2020
|
|
4ICX
| |
4ICW
| |
4IHB
| |
4IQH
| |
6ANJ
| Synaptotagmin-7, C2A domain | Descriptor: | ACETATE ION, CALCIUM ION, Synaptotagmin-7, ... | Authors: | Tomchick, D.R, Rizo, J, Voleti, R. | Deposit date: | 2017-08-13 | Release date: | 2017-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
6ANK
| Synaptotagmin-7, C2A- and C2B-domains | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Synaptotagmin-7 | Authors: | Tomchick, D.R, Rizo, J, Voleti, R. | Deposit date: | 2017-08-13 | Release date: | 2017-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.254 Å) | Cite: | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|