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3HN8
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BU of 3hn8 by Molmil
Crystal structure of synaptotagmin
Descriptor: CALCIUM ION, Synaptotagmin-3, ZINC ION
Authors:Strop, P, Vrljic, M, Ernst, J, Brunger, A.T.
Deposit date:2009-05-30
Release date:2010-02-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion.
Nat.Struct.Mol.Biol., 17, 2010
3TWY
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BU of 3twy by Molmil
RAT PKC C2 DOMAIN BOUND TO PB
Descriptor: LEAD (II) ION, Protein kinase C alpha type, SULFATE ION
Authors:Li, P.
Deposit date:2011-09-22
Release date:2011-11-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Pb2+ as Modulator of Protein-Membrane Interactions.
J.Am.Chem.Soc., 133, 2011
2Z0U
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BU of 2z0u by Molmil
Crystal structure of C2 domain of KIBRA protein
Descriptor: WW domain-containing protein 1
Authors:Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-07
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of C2 domain of KIBRA protein
To be Published
2YOA
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BU of 2yoa by Molmil
Synaptotagmin-1 C2B domain with phosphoserine
Descriptor: CALCIUM ION, PHOSPHOSERINE, SYNAPTOTAGMIN-1, ...
Authors:Honigmann, A, van den Bogaart, G, Iraheta, E, Risselada, H.J, Milovanovic, D, Mueller, V, Muellar, S, Diederichsen, U, Fasshauer, D, Grubmuller, H, Hell, S.W, Eggeling, C, Kuhnel, K, Jahn, R.
Deposit date:2012-10-22
Release date:2013-03-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Phosphatidylinositol 4,5-Bisphosphate Clusters Act as Molecular Beacons for Vesicle Recruitment
Nat.Struct.Mol.Biol., 20, 2013
3W56
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BU of 3w56 by Molmil
Structure of a C2 domain
Descriptor: C2 domain protein
Authors:Traore, D.A.K, Whisstock, J.C.
Deposit date:2013-01-24
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Defining the interaction of perforin with calcium and the phospholipid membrane.
Biochem.J., 456, 2013
3L9B
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BU of 3l9b by Molmil
Crystal Structure of Rat Otoferlin C2A
Descriptor: MAGNESIUM ION, Otoferlin
Authors:Helfmann, S, Neumann, P.
Deposit date:2010-01-04
Release date:2011-01-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The crystal structure of the C2A domain of otoferlin reveals an unconventional top loop region.
J.Mol.Biol., 406, 2011
3W57
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BU of 3w57 by Molmil
Structure of a C2 domain
Descriptor: C2 domain protein, CALCIUM ION
Authors:Traore, D.A.K, Whisstock, J.C.
Deposit date:2013-01-24
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.662 Å)
Cite:Defining the interaction of perforin with calcium and the phospholipid membrane.
Biochem.J., 456, 2013
5H4Z
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BU of 5h4z by Molmil
Crystal structure of S202G mutant of human SYT-5 C2A domain
Descriptor: CALCIUM ION, CHLORIDE ION, Synaptotagmin-5
Authors:Qiu, X, Ge, J, Yan, X, Gao, Y, Teng, M, Niu, L.
Deposit date:2016-11-02
Release date:2016-11-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain
Int. J. Biol. Macromol., 95, 2017
5H4Y
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Crystal structure of human synaptotagmin 5 C2A domain
Descriptor: ACETATE ION, CALCIUM ION, Synaptotagmin-5
Authors:Qiu, X, Gao, Y, Teng, M, Niu, L.
Deposit date:2016-11-02
Release date:2016-11-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain
Int. J. Biol. Macromol., 95, 2017
5LO8
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BU of 5lo8 by Molmil
The C2B domain of Rabphilin 3A in complex with PI(4,5)P2
Descriptor: CALCIUM ION, GLYCEROL, Rabphilin-3A, ...
Authors:Ferrer-Orta, C, Verdaguer, N.
Deposit date:2016-08-08
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural characterization of the Rabphilin-3A-SNAP25 interaction.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LOB
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BU of 5lob by Molmil
Structure of the Ca2+-bound Rabphilin3A C2B- SNAP25 complex (C2 space group)
Descriptor: CALCIUM ION, GLYCEROL, Rabphilin-3A, ...
Authors:Ferrer-Orta, C, Verdaguer, N.
Deposit date:2016-08-09
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural characterization of the Rabphilin-3A-SNAP25 interaction.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LOW
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BU of 5low by Molmil
Structure of the Ca2+-bound Rabphilin 3A C2B domain SNAP25 complex (P21 space group)
Descriptor: CALCIUM ION, GLYCEROL, Rabphilin-3A, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2016-08-10
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural characterization of the Rabphilin-3A-SNAP25 interaction.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8FAF
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BU of 8faf by Molmil
Unedited Octopus bimaculoides Synaptotagmin 1 C2A at room temperature
Descriptor: Synaptotagmin
Authors:McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.C, Sutton, R.B.
Deposit date:2022-11-26
Release date:2023-07-19
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Temperature-dependent RNA editing in octopus extensively recodes the neural proteome.
Cell, 186, 2023
8FAM
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BU of 8fam by Molmil
Edited Octopus bimaculoides Synaptotagmin 1 C2A (I248V) at room temperature
Descriptor: Synaptotagmin
Authors:McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.J, Sutton, R.B.
Deposit date:2022-11-28
Release date:2023-07-19
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Temperature-dependent RNA editing in octopus extensively recodes the neural proteome.
Cell, 186, 2023
6TZ3
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BU of 6tz3 by Molmil
Crystal Structure of Human Synaptotagmin 1 C2B without Ca2+
Descriptor: SULFATE ION, Synaptotagmin-1
Authors:Dominguez, M.J, Karmakar, S, Meyer, A.G, Sutton, R.B.
Deposit date:2019-08-09
Release date:2020-05-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
6U41
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BU of 6u41 by Molmil
1.7 angstrom structure of a pathogenic human Syt 1 C2B (D304G)
Descriptor: SULFATE ION, Synaptotagmin-1
Authors:Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B.
Deposit date:2019-08-22
Release date:2020-05-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
6U4U
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BU of 6u4u by Molmil
1.3 A structure of a pathogenic human Syt 1 C2B (I368T)
Descriptor: SULFATE ION, Synaptotagmin-1
Authors:Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B.
Deposit date:2019-08-26
Release date:2020-05-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
5YQ3
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BU of 5yq3 by Molmil
Solution NMR Structure and Backbone Dynamics of the Partially Disordered Arabidopsis thaliana Phloem Protein 16-1, A Putative mRNA Transporter
Descriptor: At3g55470
Authors:Bhuyan, A.K, Sashi, P.
Deposit date:2017-11-04
Release date:2018-04-18
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution NMR Structure and Backbone Dynamics of Partially Disordered Arabidopsis thaliana Phloem Protein 16-1, a Putative mRNA Transporter.
Biochemistry, 57, 2018
6U4W
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BU of 6u4w by Molmil
1.4 A structure of a pathogenic human Syt 1 C2B (D366E)
Descriptor: SULFATE ION, Synaptotagmin-1
Authors:Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B.
Deposit date:2019-08-26
Release date:2020-05-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
4ICX
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BU of 4icx by Molmil
N-terminal C2 domain of human CEP120
Descriptor: Centrosomal protein of 120 kDa
Authors:Janowski, R, Guarin, N, Coll, M.
Deposit date:2012-12-11
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:N-terminal C2 domain tandem of human CEP120 shows lipid binding properties
To be Published
4ICW
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BU of 4icw by Molmil
N-terminal C2 domain of human CEP120
Descriptor: Centrosomal protein of 120 kDa
Authors:Janowski, R, Guarin, N, Coll, M.
Deposit date:2012-12-11
Release date:2014-06-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:N-terminal C2 domain tandem of human CEP120 shows lipid binding properties
To be Published
4IHB
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BU of 4ihb by Molmil
X-RAY STRUCTURE OF THE canonical C2A DOMAIN FROM HUMAN DYSFERLIN
Descriptor: CALCIUM ION, Dysferlin, FORMIC ACID
Authors:Sutton, R.B, Fuson, K.L.
Deposit date:2012-12-18
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.044 Å)
Cite:Alternate Splicing of Dysferlin C2A Confers Ca(2+)-Dependent and Ca(2+)-Independent Binding for Membrane Repair.
Structure, 22, 2014
4IQH
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BU of 4iqh by Molmil
Crystal Structure Analysis of Dysferlin C2A variant 1 (C2Av1)
Descriptor: Dysferlin
Authors:Sutton, R.B, Fuson, K.L.
Deposit date:2013-01-11
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.764 Å)
Cite:Alternate Splicing of Dysferlin C2A Confers Ca(2+)-Dependent and Ca(2+)-Independent Binding for Membrane Repair.
Structure, 22, 2014
6ANJ
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BU of 6anj by Molmil
Synaptotagmin-7, C2A domain
Descriptor: ACETATE ION, CALCIUM ION, Synaptotagmin-7, ...
Authors:Tomchick, D.R, Rizo, J, Voleti, R.
Deposit date:2017-08-13
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ANK
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BU of 6ank by Molmil
Synaptotagmin-7, C2A- and C2B-domains
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Synaptotagmin-7
Authors:Tomchick, D.R, Rizo, J, Voleti, R.
Deposit date:2017-08-13
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.254 Å)
Cite:Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

217705

PDB entries from 2024-03-27

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