3NX0
 
 | | Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C | | Descriptor: | Cystatin-C, SULFATE ION | | Authors: | Orlikowska, M, Jankowska, E, Kolodziejczyk, R, Jaskolski, M, Szymanska, A. | | Deposit date: | 2010-07-12 | | Release date: | 2010-12-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C.
J.Struct.Biol., 173, 2011
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3PS8
 | | Crystal structure of L68V mutant of human cystatin C | | Descriptor: | ACETATE ION, Cystatin-C, DI(HYDROXYETHYL)ETHER | | Authors: | Orlikowska, M, Borek, D, Otwinowski, Z, Skowron, P, Szymanska, A. | | Deposit date: | 2010-12-01 | | Release date: | 2011-12-21 | | Last modified: | 2013-04-03 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal structure of L68V mutant of human cystatin C
To be Published
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3QRD
 | | Crystal structure of L68V mutant of human cystatin C | | Descriptor: | Cystatin-C, DI(HYDROXYETHYL)ETHER | | Authors: | Orlikowska, M, Borek, D, Otwinowski, Z, Skowron, P, Szymanska, A. | | Deposit date: | 2011-02-17 | | Release date: | 2012-02-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Crystal structure of L68V mutant of human cystatin C
To be Published
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1R4C
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1RN7
 | | Structure of human cystatin D | | Descriptor: | Cystatin D | | Authors: | Alvarez-Fernandez, M, Liang, Y.H, Abrahamson, M, Su, X.D. | | Deposit date: | 2003-11-30 | | Release date: | 2004-05-18 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of human cystatin D, a cysteine peptidase inhibitor with restricted inhibition profile.
J.Biol.Chem., 280, 2005
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3L0R
 | | Crystal Structure of Salivary Cystatin from the Soft Tick Ornithodoros moubata | | Descriptor: | CHLORIDE ION, Cystatin-2, GLYCEROL | | Authors: | Rezacova, P, Brynda, J, Andersen, J.F, Salat, J, Kovarova, Z, Mares, M. | | Deposit date: | 2009-12-10 | | Release date: | 2010-06-30 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata
Biochem.J., 429, 2010
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1ROA
 | | Structure of human cystatin D | | Descriptor: | Cystatin D | | Authors: | Alvarez-Fernandez, M, Liang, Y.H, Abrahamson, M, Su, X.D. | | Deposit date: | 2003-12-01 | | Release date: | 2004-05-18 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of human cystatin D, a cysteine peptidase inhibitor with restricted inhibition profile.
J.Biol.Chem., 280, 2005
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3LH4
 | | Crystal Structure of Sialostatin L2 | | Descriptor: | GLYCEROL, SULFATE ION, Secreted cystatin | | Authors: | Andersen, J.F, Kotsyfakis, M, Salat, J, Horka, H. | | Deposit date: | 2010-01-21 | | Release date: | 2010-09-29 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model.
Mol.Microbiol., 77, 2010
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1TIJ
 | | 3D Domain-swapped human cystatin C with amyloid-like intermolecular beta-sheets | | Descriptor: | Cystatin C | | Authors: | Janowski, R, Kozak, M, Abrahamson, M, Grubb, A, Jaskolski, M. | | Deposit date: | 2004-06-02 | | Release date: | 2005-07-19 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.03 Å) | | Cite: | 3D domain-swapped human cystatin C with amyloidlike intermolecular beta-sheets.
Proteins, 61, 2005
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1DVD
 | | SOLUTION NMR STRUCTURE OF HUMAN STEFIN A AT PH 5.5 AND 308K, NMR, 17 STRUCTURES | | Descriptor: | STEFIN A | | Authors: | Martin, J.R, Craven, C.J, Jerala, R, Kroon-Zitko, L, Zerovnik, E, Turk, V, Waltho, J.P. | | Deposit date: | 1996-02-26 | | Release date: | 1996-08-01 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | The three-dimensional solution structure of human stefin A.
J.Mol.Biol., 246, 1995
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1DVC
 | | SOLUTION NMR STRUCTURE OF HUMAN STEFIN A AT PH 5.5 AND 308K, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | STEFIN A | | Authors: | Martin, J.R, Craven, C.J, Jerala, R, Kroon-Zitko, L, Zerovnik, E, Turk, V, Waltho, J.P. | | Deposit date: | 1996-02-26 | | Release date: | 1996-08-01 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | The three-dimensional solution structure of human stefin A.
J.Mol.Biol., 246, 1995
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1EQK
 | | SOLUTION STRUCTURE OF ORYZACYSTATIN-I, A CYSTEINE PROTEINASE INHIBITOR OF THE RICE, ORYZA SATIVA L. JAPONICA | | Descriptor: | ORYZACYSTATIN-I | | Authors: | Nagata, K, Kudo, N, Abe, K, Arai, S, Tanokura, M. | | Deposit date: | 2000-04-05 | | Release date: | 2001-01-10 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional solution structure of oryzacystatin-I, a cysteine proteinase inhibitor of the rice, Oryza sativa L. japonica.
Biochemistry, 39, 2000
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4LZI
 | | Characterization of Solanum tuberosum Multicystatin and Significance of Core Domains | | Descriptor: | Multicystatin | | Authors: | Nissen, M.S, Kumar, G.N, Green, A.R, Knowles, N.R, Kang, C. | | Deposit date: | 2013-07-31 | | Release date: | 2014-02-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Characterization of Solanum tuberosum Multicystatin and the Significance of Core Domains.
Plant Cell, 25, 2013
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4N6L
 | | Crystal structure of human cystatin E/M | | Descriptor: | Cystatin-M | | Authors: | Dall, E, Brandstetter, H. | | Deposit date: | 2013-10-14 | | Release date: | 2015-02-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.952 Å) | | Cite: | Structure and mechanism of an aspartimide-dependent Peptide ligase in human legumain.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4N6M
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4N6V
 | | Partial rotational order disorder structure of human stefin B | | Descriptor: | Cystatin-B, SULFATE ION | | Authors: | Renko, M, Taler-Vercic, A, Mihelic, M, Zerovnik, E, Turk, D. | | Deposit date: | 2013-10-14 | | Release date: | 2014-04-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Partial rotational lattice order-disorder in stefin B crystals.
Acta Crystallogr.,Sect.D, 70, 2014
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1GD4
 | | SOLUTION STRUCTURE OF P25S CYSTATIN A | | Descriptor: | CYSTATIN A | | Authors: | Shimba, N, Kariya, E, Tate, S, Kaji, H, Kainosho, M. | | Deposit date: | 2000-09-08 | | Release date: | 2001-09-08 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structural comparison between wild-type and P25S human cystatin A by NMR spectroscopy. Does this mutation affect the a-helix conformation ?
J.STRUCT.FUNCT.GENOM., 1, 2000
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1G96
 | | HUMAN CYSTATIN C; DIMERIC FORM WITH 3D DOMAIN SWAPPING | | Descriptor: | CHLORIDE ION, CYSTATIN C, GLYCEROL | | Authors: | Janowski, R, Kozak, M, Jankowska, E, Grzonka, Z, Grubb, A, Abrahamson, M, Jaskolski, M. | | Deposit date: | 2000-11-22 | | Release date: | 2001-04-06 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping.
Nat.Struct.Biol., 8, 2001
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1GD3
 | | refined solution structure of human cystatin A | | Descriptor: | CYSTATIN A | | Authors: | Shimba, N, Kariya, E, Tate, S, Kaji, H, Kainosho, M. | | Deposit date: | 2000-09-08 | | Release date: | 2001-09-08 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structural comparison between wild-type and P25S human cystatin A by NMR spectroscopy. Does this mutation affect the a-helix
conformation ?
J.STRUCT.FUNCT.GENOM., 1, 2000
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7AUW
 | | Inhibitory complex of human meprin beta with mouse fetuin-B. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fetuin-B, ... | | Authors: | Eckhard, U, Gomis-Ruth, F.X. | | Deposit date: | 2020-11-03 | | Release date: | 2021-04-14 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The crystal structure of a 250-kDa heterotetrameric particle explains inhibition of sheddase meprin beta by endogenous fetuin-B.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6HT9
 | | Mouse fetuin-B in complex with crayfish astacin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Astacin, ... | | Authors: | Gomis-Ruth, F.X, Goulas, T, Guevara, T, Cuppari, A. | | Deposit date: | 2018-10-03 | | Release date: | 2019-03-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition.
Iucrj, 6, 2019
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7PK4
 | | Tick salivary cystatin Ricistatin in complex with cathepsin V | | Descriptor: | 1,2-ETHANEDIOL, Cathepsin L2, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Busa, M, Mares, M. | | Deposit date: | 2021-08-25 | | Release date: | 2022-12-14 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Protease-bound structure of Ricistatin provides insights into the mechanism of action of tick salivary cystatins in the vertebrate host.
Cell.Mol.Life Sci., 80, 2023
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7UAI
 | | Meprin alpha helix in complex with fetuin-B | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C. | | Deposit date: | 2022-03-13 | | Release date: | 2022-11-02 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Nat Commun, 13, 2022
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1YVB
 | | the Plasmodium falciparum Cysteine Protease Falcipain-2 | | Descriptor: | Cystatin, GLYCEROL, falcipain 2 | | Authors: | Wang, S.X. | | Deposit date: | 2005-02-15 | | Release date: | 2006-03-28 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for unique mechanisms of folding and hemoglobin binding by a malarial protease.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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8GT7
 | | Structure of falcipain and human Stefin A mutant complex | | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Cystatin-A, ... | | Authors: | Chakraborty, S, Biswas, S. | | Deposit date: | 2022-09-07 | | Release date: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.28 Å) | | Cite: | Structure of falcipain and human Stefin A complex
To Be Published
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