5XG9
 
 | | Crystal Structure of PEG-bound SH3 domain of Myosin IB from Entamoeba histolytica | | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, PENTAETHYLENE GLYCOL, ... | | Authors: | Gautam, G, Gourinath, S. | | Deposit date: | 2017-04-13 | | Release date: | 2017-08-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition
Acta Crystallogr D Struct Biol, 73, 2017
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6XVN
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6XVM
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7S4R
 | | Serial Macromolecular Crystallography at ALBA Synchrotron Light Source - alpha Spectrin-SH3 domain | | Descriptor: | Spectrin alpha chain, non-erythrocytic 1 | | Authors: | Martin-Garcia, J.M, Botha, S, Hu, H, Jernigan, R, Castellvi, A, Lisova, S, Gil, F, Calisto, B, Crespo, I, Roy-Chowdbury, S, Grieco, A, Ketawala, G, Weierstall, U, Spence, J, Fromme, P, Zatsepin, N, Boer, R, Carpena, X. | | Deposit date: | 2021-09-09 | | Release date: | 2021-10-27 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Serial macromolecular crystallography at ALBA Synchrotron Light Source.
J.Synchrotron Radiat., 29, 2022
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7TPB
 | | p120RasGAP SH3 domain in complex with DLC1 RhoGAP domain | | Descriptor: | Ras GTPase-activating protein 1, Rho GTPase-activating protein 7 | | Authors: | Stiegler, A.L, Boggon, T.J, Chau, J.E, Vish, K.J. | | Deposit date: | 2022-01-25 | | Release date: | 2022-08-03 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP.
Nat Commun, 13, 2022
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7CFZ
 | | SH3 domain of NADPH oxidase activator 1 | | Descriptor: | NADPH oxidase activator 1 | | Authors: | Kim, M, Park, J.H, Attri, P, Lee, W. | | Deposit date: | 2020-06-29 | | Release date: | 2021-07-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Structural modification of NADPH oxidase activator (Noxa 1) by oxidative stress: An experimental and computational study.
Int.J.Biol.Macromol., 163, 2020
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7TZK
 | | EPS8 SH3 Domain with NleH1 PxxDY Motif | | Descriptor: | Epidermal growth factor receptor kinase substrate 8, T3SS secreted effector NleH homolog | | Authors: | Grishin, A.M, Cygler, M. | | Deposit date: | 2022-02-15 | | Release date: | 2022-07-06 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.43 Å) | | Cite: | Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli
Proc.Natl.Acad.Sci.USA, 119, 2022
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7Y4N
 | | Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos | | Descriptor: | Growth factor receptor-bound protein 2 | | Authors: | Pooppadi, M.S, Ikeya, T, Sugasawa, H, Watanabe, R, Mishima, M, Inomata, K, Ito, Y. | | Deposit date: | 2022-06-15 | | Release date: | 2022-08-31 | | Method: | SOLUTION NMR | | Cite: | Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos.
Biochem.Biophys.Res.Commun., 625, 2022
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7YXW
 | | Structure of the p22phox A200G mutant in complex with p47phox peptide | | Descriptor: | Cytochrome b-245 light chain, Neutrophil cytosol factor 1 | | Authors: | Cukier, C.D, Vuillard, L.M, Komjati, B, Szlavik, Z. | | Deposit date: | 2022-02-16 | | Release date: | 2022-03-30 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics
Acs Med.Chem.Lett., 13, 2022
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4EIK
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4ESR
 | | Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors | | Descriptor: | DI(HYDROXYETHYL)ETHER, Jouberin | | Authors: | Van Petegem, X.F, Liu, P.X, Lobo, P, Jiang, X. | | Deposit date: | 2012-04-23 | | Release date: | 2012-06-06 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitors.
Proteomics, 12, 2012
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4F16
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4F17
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5HCK
 | | HUMAN HCK SH3 DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | HEMATOPOIETIC CELL KINASE | | Authors: | Horita, D.A, Baldisseri, D.M, Zhang, W, Altieri, A.S, Smithgall, T.E, Gmeiner, W.H, Byrd, R.A. | | Deposit date: | 1998-03-09 | | Release date: | 1998-06-17 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the human Hck SH3 domain and identification of its ligand binding site.
J.Mol.Biol., 278, 1998
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5ZAU
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3NGP
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5I11
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5IHK
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5IHN
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6A9C
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5IH2
 | | Structure, thermodynamics, and the role of conformational dynamics in the interactions between the N-terminal SH3 domain of CrkII and proline-rich motifs in cAbl | | Descriptor: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Adapter molecule crk, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Bhatt, V.S, Zeng, D, Krieger, I, Sacchettini, J.C, Cho, J.-H. | | Deposit date: | 2016-02-28 | | Release date: | 2016-06-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Binding Mechanism of the N-Terminal SH3 Domain of CrkII and Proline-Rich Motifs in cAbl.
Biophys.J., 110, 2016
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5IHI
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6ATV
 | | The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions | | Descriptor: | Adapter molecule crk, proline-rich motif in IAV-NS1 | | Authors: | Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H. | | Deposit date: | 2017-08-29 | | Release date: | 2018-08-08 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.751 Å) | | Cite: | Molecular Mechanisms of Tight Binding through Fuzzy Interactions.
Biophys. J., 114, 2018
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6C4S
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4RTT
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