2F2X
 
 | | alpha-spectrin SH3 domain R21G mutant | | Descriptor: | SULFATE ION, Spectrin alpha chain, brain | | Authors: | Camara-Artigas, A, Conejero-Lara, F, Casares, S, Lopez-Mayorga, O, Vega, C. | | Deposit date: | 2005-11-18 | | Release date: | 2006-10-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain
Proteins, 67, 2007
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2FRY
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2GBQ
 | | SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, 15 STRUCTURES | | Descriptor: | GRB2, SOS-1 | | Authors: | Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L. | | Deposit date: | 1996-12-23 | | Release date: | 1997-09-04 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
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2GNC
 | | Crystal structure of srGAP1 SH3 domain in the slit-robo signaling pathway | | Descriptor: | SLIT-ROBO Rho GTPase-activating protein 1 | | Authors: | Li, X, Liu, Y, Gao, F, Bartlam, M, Wu, J.Y, Rao, Z. | | Deposit date: | 2006-04-10 | | Release date: | 2006-07-18 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis of Robo Proline-rich Motif Recognition by the srGAP1 Src Homology 3 Domain in the Slit-Robo Signaling Pathway
J.Biol.Chem., 281, 2006
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2HDA
 | | Yes SH3 domain | | Descriptor: | Proto-oncogene tyrosine-protein kinase Yes, SULFATE ION | | Authors: | Camara-Artigas, A, Luque, I, Ruiz-Sanz, J, Mateo, P.L, Martin-Garcia, J.M. | | Deposit date: | 2006-06-20 | | Release date: | 2007-04-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic structure of the SH3 domain of the human c-Yes tyrosine kinase: Loop flexibility and amyloid aggregation.
Febs Lett., 581, 2007
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2GQI
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2HSP
 | | SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA | | Descriptor: | PHOSPHOLIPASE C-GAMMA (SH3 DOMAIN) | | Authors: | Kohda, D, Hatanaka, H, Odaka, M, Inagaki, F. | | Deposit date: | 1994-06-13 | | Release date: | 1994-08-31 | | Last modified: | 2017-11-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the SH3 domain of phospholipase C-gamma.
Cell(Cambridge,Mass.), 72, 1993
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2J06
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2J05
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2IIM
 | | SH3 Domain of Human Lck | | Descriptor: | CALCIUM ION, Proto-oncogene tyrosine-protein kinase LCK, TETRAETHYLENE GLYCOL, ... | | Authors: | Romir, J, Egerer-Sieber, C, Muller, Y.A. | | Deposit date: | 2006-09-28 | | Release date: | 2006-11-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs.
J.Mol.Biol., 365, 2007
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2JM8
 | | R21A Spc-SH3 free | | Descriptor: | Spectrin alpha chain, brain | | Authors: | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | | Deposit date: | 2006-10-25 | | Release date: | 2007-04-24 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3
Bmc Struct.Biol., 7, 2007
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2JW4
 | | NMR solution structure of the N-terminal SH3 domain of human Nckalpha | | Descriptor: | Cytoplasmic protein NCK1 | | Authors: | Santiveri, C.M, Borroto, A, Simon, L, Rico, M, Ortiz, A.R, Alarcon, B, Jimenez, M. | | Deposit date: | 2007-10-05 | | Release date: | 2008-08-26 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Interaction between the N-terminal SH3 domain of Nckalpha and CD3epsilon-derived peptides: Non-canonical and canonical recognition motifs
BIOCHEM.BIOPHYS.ACTA PROTEINS & PROTEOMICS, 1794, 2009
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2K3B
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2JTE
 | | Third SH3 domain of CD2AP | | Descriptor: | CD2-associated protein | | Authors: | van Nuland, N.A.J, Ortega, R.J, Romero Romero, M, Ab, E, Ora, A, Lopez, M.O, Azuaga, A.I. | | Deposit date: | 2007-07-28 | | Release date: | 2007-12-11 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | The high resolution NMR structure of the third SH3 domain of CD2AP.
J.Biomol.Nmr, 39, 2007
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2JXB
 | | Structure of CD3epsilon-Nck2 first SH3 domain complex | | Descriptor: | T-cell surface glycoprotein CD3 epsilon chain, Cytoplasmic protein NCK2 | | Authors: | Takeuchi, K, Yang, H, Ng, E, Park, S, Sun, Z.J, Reinherz, E.L, Wagner, G. | | Deposit date: | 2007-11-09 | | Release date: | 2008-09-23 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity.
J.Mol.Biol., 380, 2008
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2JMA
 | | R21A Spc-SH3:P41 complex | | Descriptor: | P41 peptide, Spectrin alpha chain, brain | | Authors: | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | | Deposit date: | 2006-10-25 | | Release date: | 2007-04-24 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3
Bmc Struct.Biol., 7, 2007
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2JS2
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2JS0
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2K2M
 | | Structural Basis of PxxDY Motif Recognition in SH3 Binding | | Descriptor: | Eps8-like protein 1 | | Authors: | Aitio, O, Hellman, M, Kesti, T, Kleino, I, Samuilova, O, Tossavainen, H, Saksela, K, Permi, P. | | Deposit date: | 2008-04-02 | | Release date: | 2009-02-17 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural basis of PxxDY motif recognition in SH3 binding.
J.Mol.Biol., 382, 2008
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2JM9
 | | R21A Spc-SH3 bound | | Descriptor: | Spectrin alpha chain, brain | | Authors: | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | | Deposit date: | 2006-10-25 | | Release date: | 2007-04-24 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3
Bmc Struct.Biol., 7, 2007
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2JMC
 | | Chimer between Spc-SH3 and P41 | | Descriptor: | Spectrin alpha chain, brain and P41 peptide chimera | | Authors: | van Nuland, N.A.J, Candel, A.M, Martinez, J.C, Conejero-Lara, F, Bruix, M. | | Deposit date: | 2006-11-02 | | Release date: | 2007-04-24 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | The high-resolution NMR structure of a single-chain chimeric protein mimicking a SH3-peptide complex
Febs Lett., 581, 2007
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2KGT
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2KR3
 | | Solution structure of SHA-D | | Descriptor: | Spectrin alpha chain, brain | | Authors: | Khristoforov, V.S, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Gushchina, L.V, Filimonov, V.V, Kutyshenko, V.P. | | Deposit date: | 2009-12-03 | | Release date: | 2010-09-15 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Chimeric SHA-D domain "SH3-Bergerac": 3D structure and dynamics studies
Russ.J.Bioorganic Chem., 36, 2010
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2KYM
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2KRO
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