8S5N
| RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | Deposit date: | 2024-02-24 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Three-step mechanism of promoter escape by RNA polymerase II To Be Published
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8RP5
| Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (E241A mutant) | Descriptor: | 1,2-ETHANEDIOL, Alpha-methylacyl-CoA racemase, TRIETHYLENE GLYCOL | Authors: | Mojanaga, O.O, Acharya, K.R, Lloyd, M.D. | Deposit date: | 2024-01-12 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | alpha-Methylacyl-CoA Racemase from Mycobacterium tuberculosis -Detailed Kinetic and Structural Characterization of the Active Site. Biomolecules, 14, 2024
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9B4H
| Chlamydomonas reinhardtii mastigoneme filament | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain-containing protein, Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein, ... | Authors: | Dai, J, Ma, M, Zhang, R, Brown, A. | Deposit date: | 2024-03-20 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyproline-rich helices. Cell, 2024
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8RDT
| Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8j | Descriptor: | (5~{S})-3-(2,3,4-trimethoxyphenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ... | Authors: | Bischof, L, Hartmann, M.D. | Deposit date: | 2023-12-08 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode. Eur.J.Med.Chem., 270, 2024
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9B7E
| S_SAD structure of HEWL using lossy compression data with a compression ratio of 422 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | Authors: | Jakoncic, J, Bernstein, H.J, Soares, A.S, Horvat, K. | Deposit date: | 2024-03-27 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Investigation of fast and efficient lossless compression algorithms for macromolecular crystallography experiments To Be Published
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8RMW
| Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis. | Descriptor: | 1,2-ETHANEDIOL, Alpha-methylacyl-CoA racemase, DI(HYDROXYETHYL)ETHER | Authors: | Mojanaga, O.O, Acharya, K.R, Lloyd, M.D. | Deposit date: | 2024-01-09 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | alpha-Methylacyl-CoA Racemase from Mycobacterium tuberculosis -Detailed Kinetic and Structural Characterization of the Active Site. Biomolecules, 14, 2024
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9B7F
| S_SAD structure of HEWL using lossless default compression | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | Authors: | Jakoncic, J, Bernstein, H.J, Soares, A.S, Horvat, K. | Deposit date: | 2024-03-27 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Investigation of fast and efficient lossless compression algorithms for macromolecular crystallography experiments To Be Published
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9B8D
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8RU2
| Structure of the F-actin barbed end bound by formin mDia1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | Deposit date: | 2024-01-29 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Molecular mechanism of actin filament elongation by formins Science, 384, 2024
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9B8E
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8S9J
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9EQ3
| Structure of IgE HMM5 bound to FceRIa cryo-EM class 8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, ... | Authors: | Andersen, G.R, Jensen, R.K. | Deposit date: | 2024-03-20 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Structure of IgE HMM5 bound to FceRIa cryo-EM class 8 To be published
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9ER3
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8RTT
| Structure of the formin Cdc12 bound to the barbed end of phalloidin-stabilized F-actin. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | Deposit date: | 2024-01-29 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Mechanism of formin-mediated processive elongation of actin filaments revealed by cryo-EM To Be Published
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8R8R
| Cryo-EM structure of the human mPSF with PAPOA C-terminus peptide (PAPOAc) | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*A)-3'), ... | Authors: | Todesca, S, Sandmeir, F, Keidel, A, Conti, E. | Deposit date: | 2023-11-29 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Molecular basis of human polyA polymerase recruitment by mPSF. Rna, 2024
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8ROM
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8RV2
| Structure of the formin INF2 bound to the barbed end of F-actin. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | Deposit date: | 2024-01-31 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Molecular mechanism of actin filament elongation by formins Science, 384, 2024
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8S9R
| SAL2, Staphylococcus aureus lipase 2 (geh, lip2), apo form | Descriptor: | CALCIUM ION, Lipase 2, PHOSPHATE ION, ... | Authors: | Fellner, M. | Deposit date: | 2023-03-30 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | SAL2, Staphylococcus aureus lipase 2 (geh, lip2), apo form To Be Published
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8QEY
| Structure of human Asc1/CD98hc heteromeric amino acid transporter | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ... | Authors: | Martinez-Molledo, M, Rullo-Tubau, J, Errasti-Murugarren, E, Palacin, M, Llorca, O. | Deposit date: | 2023-09-01 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter. Nat Commun, 15, 2024
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8R5T
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8RP4
| Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (D156A mutant) | Descriptor: | 1,2-ETHANEDIOL, Alpha-methylacyl-CoA racemase, DI(HYDROXYETHYL)ETHER | Authors: | Mojanaga, O.O, Acharya, K.R, Lloyd, M.D. | Deposit date: | 2024-01-12 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | alpha-Methylacyl-CoA Racemase from Mycobacterium tuberculosis -Detailed Kinetic and Structural Characterization of the Active Site. Biomolecules, 14, 2024
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8RVE
| Vimentin intermediate filament | Descriptor: | Vimentin | Authors: | Eibauer, M, Medalia, O. | Deposit date: | 2024-02-01 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Vimentin filaments integrate low-complexity domains in a complex helical structure Nat.Struct.Mol.Biol., 2024
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8PSV
| 2.7 A cryo-EM structure of in vitro assembled type 1 pilus rod | Descriptor: | Type-1 fimbrial protein, A chain | Authors: | Hospenthal, M, Zyla, D, Glockshuber, R, Waksman, G. | Deposit date: | 2023-07-13 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili. Nat Commun, 15, 2024
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8PTU
| 2.5 A cryo-EM structure of the in vitro FimD-catalyzed assembly of type 1 pilus rod | Descriptor: | Type-1 fimbrial protein, A chain | Authors: | Zyla, D, Hospenthal, M, Glockshuber, R, Waksman, G. | Deposit date: | 2023-07-14 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili. Nat Commun, 15, 2024
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8P0M
| Crystal structure of TEAD3 in complex with IAG933 | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 4-[(2~{S})-5-chloranyl-6-fluoranyl-2-phenyl-2-[(2~{S})-pyrrolidin-2-yl]-3~{H}-1-benzofuran-4-yl]-5-fluoranyl-6-(2-hydroxyethyloxy)-~{N}-methyl-pyridine-3-carboxamide, DIMETHYL SULFOXIDE, ... | Authors: | Scheufler, C, Villard, F, Chau, S. | Deposit date: | 2023-05-10 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.961 Å) | Cite: | Direct and selective pharmacological disruption of the YAP-TEAD interface by IAG933 inhibits Hippo-dependent and RAS-MAPK-altered cancers. Nat Cancer, 2024
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