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5T1I
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BU of 5t1i by Molmil
CBX3 chromo shadow domain in complex with histone H3 peptide
Descriptor: Chromobox protein homolog 3, Histone H3.1, UNKNOWN ATOM OR ION
Authors:Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2016-08-19
Release date:2016-09-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Peptide recognition by heterochromatin protein 1 (HP1) chromoshadow domains revisited: Plasticity in the pseudosymmetric histone binding site of human HP1.
J. Biol. Chem., 292, 2017
7OS4
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BU of 7os4 by Molmil
Crystal structure of mouse CARM1 in complex with histone H3_13-31 K18
Descriptor: (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, Histone H3.1, Histone-arginine methyltransferase CARM1
Authors:Marechal, N, Cura, V, Troffer-Charlier, N, Bonnefond, L, Cavarelli, J.
Deposit date:2021-06-07
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Structural Studies Provide New Insights into the Role of Lysine Acetylation on Substrate Recognition by CARM1 and Inform the Design of Potent Peptidomimetic Inhibitors.
Chembiochem, 22, 2021
7OKP
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BU of 7okp by Molmil
Crystal structure of mouse CARM1 in complex with histone H3_13-22 K18 acetylated
Descriptor: (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, Histone H3.3, Histone-arginine methyltransferase CARM1, ...
Authors:Marechal, N, Cura, V, Troffer-Charlier, N, Bonnefond, L, Cavarelli, J.
Deposit date:2021-05-18
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Studies Provide New Insights into the Role of Lysine Acetylation on Substrate Recognition by CARM1 and Inform the Design of Potent Peptidomimetic Inhibitors.
Chembiochem, 22, 2021
7K7G
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BU of 7k7g by Molmil
nucleosome and Gal4 complex
Descriptor: Centromere DNA-binding protein complex CBF3 subunit B, DNA (147-MER), Histone H2A.1, ...
Authors:Ruifang, G, Yawen, B.
Deposit date:2020-09-22
Release date:2021-03-31
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Nat Commun, 12, 2021
2HUE
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BU of 2hue by Molmil
Structure of the H3-H4 chaperone Asf1 bound to histones H3 and H4
Descriptor: Anti-silencing protein 1, GLYCEROL, Histone H3, ...
Authors:English, C.M, Churchill, M.E.A, Tyler, J.K.
Deposit date:2006-07-26
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the histone chaperone activity of asf1.
Cell(Cambridge,Mass.), 127, 2006
2LH0
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BU of 2lh0 by Molmil
NMR structure of the histone-interacting N-terminal homodimeric region of Rtt106
Descriptor: Histone chaperone RTT106
Authors:Hu, Q, Cui, G, Mer, G.
Deposit date:2011-08-04
Release date:2012-02-01
Last modified:2012-03-07
Method:SOLUTION NMR
Cite:Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Nature, 483, 2012
6YN1
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BU of 6yn1 by Molmil
Crystal structure of histone chaperone APLF acidic domain bound to the histone H2A-H2B-H3-H4 octamer
Descriptor: Aprataxin and PNK-like factor, CHLORIDE ION, GLYCEROL, ...
Authors:Corbeski, I, Guo, X, Van Ingen, H, Sixma, T.K.
Deposit date:2020-04-10
Release date:2021-11-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF.
Sci Adv, 8, 2022
7CJ0
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BU of 7cj0 by Molmil
Crystal structure of DNAJC9 HBD in complex with H3.3-H4 dimer and MCM2 HBD
Descriptor: DNA replication licensing factor MCM2, DnaJ homolog subfamily C member 9, GLYCEROL, ...
Authors:Bao, H, Huang, H.
Deposit date:2020-07-09
Release date:2021-04-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network.
Mol.Cell, 81, 2021
7CIZ
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BU of 7ciz by Molmil
Crystal structure of DNAJC9 HBD helix2 in complex with H3.3-H4 dimer and MCM2 HBD
Descriptor: DNA replication licensing factor MCM2, DnaJ homolog subfamily C member 9, Histone H3.3, ...
Authors:Bao, H, Huang, H.
Deposit date:2020-07-08
Release date:2021-04-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network.
Mol.Cell, 81, 2021
7Y5V
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BU of 7y5v by Molmil
Cryo-EM structure of the dimeric human CAF1LC-H3-H4 complex
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, C, Yu, Z.Y, Xu, R.M.
Deposit date:2022-06-17
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
7Y5U
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BU of 7y5u by Molmil
Cryo-EM structure of the monomeric human CAF1LC-H3-H4 complex
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M.
Deposit date:2022-06-17
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
8P88
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BU of 8p88 by Molmil
X-ray structure of cardiotoxic light chain H3 in complex to neutralizing nanobody C4
Descriptor: CHLORIDE ION, Light Chain H3, Nanobody C4, ...
Authors:Broggini, L, Ricagno, S.
Deposit date:2023-05-31
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.022 Å)
Cite:Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation.
J.Mol.Biol., 435, 2023
8P89
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BU of 8p89 by Molmil
X-ray structure of cardiotoxic light chain H3 in complex to neutralizing nanobody B5
Descriptor: CHLORIDE ION, Light chain H3, Nanobody B5
Authors:Broggini, L, Ricagno, S.
Deposit date:2023-05-31
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.187 Å)
Cite:Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation.
J.Mol.Biol., 435, 2023
5KDM
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BU of 5kdm by Molmil
Crystal structure of EBV tegument protein BNRF1 in complex with histone chaperone DAXX and histones H3.3-H4
Descriptor: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
Authors:Huang, H, Patel, D.
Deposit date:2016-06-08
Release date:2016-09-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis underlying viral hijacking of a histone chaperone complex.
Nat Commun, 7, 2016
5Z23
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BU of 5z23 by Molmil
Crystal structure of the nucleosome containing a chimeric histone H3/CENP-A CATD
Descriptor: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Arimura, Y, Tachiwana, H, Takagi, H.
Deposit date:2017-12-28
Release date:2019-02-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism.
Nat Commun, 10, 2019
5ZBX
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BU of 5zbx by Molmil
The crystal structure of the nucleosome containing histone H3.1 CATD(V76Q, K77D)
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
Authors:Arimura, Y, Takagi, H, Kurumizaka, H.
Deposit date:2018-02-13
Release date:2019-02-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism.
Nat Commun, 10, 2019
7KF0
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BU of 7kf0 by Molmil
Crystal structure of bH1 Fab variant (CDR H3 loop design 13_0346) in complex with VEGF
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Isoform L-VEGF206 of Vascular endothelial growth factor A, ...
Authors:Shi, R, Picard, M.-E.
Deposit date:2020-10-13
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF
to be published
7KF1
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BU of 7kf1 by Molmil
Crystal structure of bH1 Fab variant (CDR H3 loop design 14_0130) in complex with VEGF
Descriptor: CHLORIDE ION, Isoform L-VEGF206 of Vascular endothelial growth factor A, anti-VEGF-A Fab bH1 heavy chain, ...
Authors:Shi, R, Picard, M.-E, Manenda, M.S.
Deposit date:2020-10-13
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF
to be published
7KEZ
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BU of 7kez by Molmil
Crystal structure of bH1 Fab variant (CDR H3 loop design 16_0325) in complex with VEGF
Descriptor: CHLORIDE ION, Isoform L-VEGF206 of Vascular endothelial growth factor A, anti-VEGF-A Fab bH1 heavy chain, ...
Authors:Shi, R, Manenda, M.S, Picard, M.-E.
Deposit date:2020-10-13
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF
to be published
4QEO
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BU of 4qeo by Molmil
crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH
Descriptor: DNA 5'-ACTGATGAGTACCAT-3', DNA 5'-GGTACT(5CM)ATCAGTAT-3', Histone H3, ...
Authors:Du, J, Li, S, Patel, D.J.
Deposit date:2014-05-17
Release date:2014-07-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55, 2014
2F6J
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BU of 2f6j by Molmil
Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4me3 bound state
Descriptor: ZINC ION, bromodomain PHD finger transcription factor, histone H3, ...
Authors:Li, H, Patel, D.J.
Deposit date:2005-11-29
Release date:2006-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
2FSA
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BU of 2fsa by Molmil
Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4ME2 bound state
Descriptor: Histone H3(1-15)K4me2 peptide, ZINC ION, bromodomain PHD finger transcription factor
Authors:Li, H, Patel, D.J.
Deposit date:2006-01-21
Release date:2006-07-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
6WW3
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BU of 6ww3 by Molmil
Crystal structure of HERC2 ZZ domain in complex with SUMO1 tail
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, SUMO1 linked HERC2 ZZ domain (Small ubiquitin-related modifier 1,E3 ubiquitin-protein ligase HERC2), ...
Authors:Liu, J, Vann, K.R, Kutateladze, T.G.
Deposit date:2020-05-07
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1.
Structure, 28, 2020
7D86
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BU of 7d86 by Molmil
Crystal Structure of zebrafishPHF14-PZP
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, PHD finger protein 14, ...
Authors:Li, H, Zheng, S.
Deposit date:2020-10-07
Release date:2021-07-28
Last modified:2022-02-09
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14.
Nucleic Acids Res., 49, 2021
3A1B
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BU of 3a1b by Molmil
Crystal structure of the DNMT3A ADD domain in complex with histone H3
Descriptor: 1,2-ETHANEDIOL, DNA (cytosine-5)-methyltransferase 3A, Histone H3.1, ...
Authors:Otani, J, Arita, K, Ariyoshi, M, Shirakawa, M.
Deposit date:2009-03-28
Release date:2009-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.292 Å)
Cite:Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain
Embo Rep., 10, 2009

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