Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2KL7
DownloadVisualize
BU of 2kl7 by Molmil
Solution NMR Structure of the EGF-like 1 Domain of Human Fibulin-4. Northeast Structural Genomics Target HR6275
Descriptor: Fibulin-4
Authors:Rossi, P, Chiang, Y, Anderson, S, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-06-30
Release date:2009-07-21
Last modified:2020-02-26
Method:SOLUTION NMR
Cite:Solution NMR Structure of the EGF-like 1 Domain of Human Fibulin-4. Northeast Structural Genomics Target HR6275
To be Published
1EMN
DownloadVisualize
BU of 1emn by Molmil
NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, MINIMIZED AVERAGE STRUCTURE
Descriptor: CALCIUM ION, FIBRILLIN
Authors:Downing, A.K, Campbell, I.D, Handford, P.A.
Deposit date:1996-08-05
Release date:1996-12-23
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders.
Cell(Cambridge,Mass.), 85, 1996
1EMO
DownloadVisualize
BU of 1emo by Molmil
NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, 22 STRUCTURES
Descriptor: CALCIUM ION, FIBRILLIN
Authors:Downing, A.K, Campbell, I.D, Handford, P.A.
Deposit date:1996-08-05
Release date:1996-12-23
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders.
Cell(Cambridge,Mass.), 85, 1996
1LMJ
DownloadVisualize
BU of 1lmj by Molmil
NMR Study of the Fibrillin-1 cbEGF12-13 Pair of Ca2+ Binding Epidermal Growth Factor-like Domains
Descriptor: CALCIUM ION, fibrillin 1
Authors:Smallridge, R.S, Whiteman, P, Werner, J.M, Campbell, I.D, Handford, P.A, Downing, A.K.
Deposit date:2002-05-02
Release date:2003-04-29
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution Structure and Dynamics of a Calcium Binding Epidermal Growth Factor-like Domain Pair from the Neonatal Region of Human Fibrillin-1.
J.Biol.Chem., 278, 2003
1Z6C
DownloadVisualize
BU of 1z6c by Molmil
Solution structure of an EGF pair (EGF34) from vitamin K-dependent protein S
Descriptor: CALCIUM ION, Vitamin K-dependent protein S
Authors:Drakenberg, T, Ghasriani, H, Thulin, E, Thamlitz, A.M, Muranyi, A, Annila, A, Stenflo, J.
Deposit date:2005-03-22
Release date:2005-06-21
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution Structure of the Ca(2+)-Binding EGF3-4 Pair from Vitamin K-Dependent Protein S: Identification of an Unusual Fold in EGF3.
Biochemistry, 44, 2005
2BOX
DownloadVisualize
BU of 2box by Molmil
EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with strontium.
Descriptor: CACODYLATE ION, CHLORIDE ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR, ...
Authors:Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M.
Deposit date:2005-04-14
Release date:2006-10-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2BOU
DownloadVisualize
BU of 2bou by Molmil
EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with barium.
Descriptor: BARIUM ION, CACODYLATE ION, CALCIUM ION, ...
Authors:Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M.
Deposit date:2005-04-14
Release date:2006-10-18
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2BO2
DownloadVisualize
BU of 2bo2 by Molmil
EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with calcium.
Descriptor: CACODYLATE ION, CALCIUM ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR
Authors:Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M.
Deposit date:2005-04-07
Release date:2006-08-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
8UFB
DownloadVisualize
BU of 8ufb by Molmil
Eastern equine encephalitis virus (PE-6) VLP in complex with full-length VLDLR (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2023-10-04
Release date:2024-01-17
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
7DO4
DownloadVisualize
BU of 7do4 by Molmil
Crystal structure of CD97-CD55 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Niu, M, Song, G.
Deposit date:2020-12-11
Release date:2021-09-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for CD97 recognition of the decay-accelerating factor CD55 suggests mechanosensitive activation of adhesion GPCRs.
J.Biol.Chem., 296, 2021
1NT0
DownloadVisualize
BU of 1nt0 by Molmil
Crystal structure of the CUB1-EGF-CUB2 region of MASP2
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Feinberg, H, Uitdehaag, J.C.M, Davies, J.M, Wallis, R, Drickamer, K, Weis, W.I.
Deposit date:2003-01-28
Release date:2003-05-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2
Embo J., 22, 2003
6TQK
DownloadVisualize
BU of 6tqk by Molmil
Cryo-EM of native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, ...
Authors:Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L.
Deposit date:2019-12-16
Release date:2020-11-04
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Cryo-EM structure of native human uromodulin, a zona pellucida module polymer.
Embo J., 39, 2020
5UK5
DownloadVisualize
BU of 5uk5 by Molmil
Complex of Notch1(EGF8-12) bound to Jagged1(N-EGF3)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Garcia, K.C, Luca, V.C.
Deposit date:2017-01-19
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.
Science, 355, 2017
1H30
DownloadVisualize
BU of 1h30 by Molmil
C-terminal LG domain pair of human Gas6
Descriptor: CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN, SULFATE ION
Authors:Sasaki, T, Knyazev, P.G, Cheburkin, Y, Gohring, W, Tisi, D, Ullrich, A, Timpl, R, Hohenester, E.
Deposit date:2002-08-21
Release date:2003-01-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Carboxy-Terminal Fragment of Growth-Arrest-Specific Protein Gas6: Receptor Tyrosine Kinase Activation by Laminin G-Like Domains
J.Biol.Chem., 277, 2002
2VJ3
DownloadVisualize
BU of 2vj3 by Molmil
Human Notch-1 EGFs 11-13
Descriptor: CALCIUM ION, CHLORIDE ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, ...
Authors:Johnson, S, Cordle, J, Tay, J.Z, Roversi, P, Lea, S.M.
Deposit date:2007-12-06
Release date:2008-07-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15, 2008
4XL1
DownloadVisualize
BU of 4xl1 by Molmil
Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Luca, V.C, Jude, K.M, Garcia, K.C.
Deposit date:2015-01-13
Release date:2015-03-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
Science, 347, 2015
4XLW
DownloadVisualize
BU of 4xlw by Molmil
Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Delta-like protein, ...
Authors:Luca, V.C, Jude, K.M, Garcia, K.C.
Deposit date:2015-01-13
Release date:2015-03-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.39 Å)
Cite:Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
Science, 347, 2015
8EM4
DownloadVisualize
BU of 8em4 by Molmil
Cryo-EM structure of LRP2 at pH 7.5
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Beenken, A, Cerutti, G, Brasch, J, Fitzpatrick, A.W, Barasch, J, Shapiro, L.
Deposit date:2022-09-26
Release date:2023-02-08
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Structures of LRP2 reveal a molecular machine for endocytosis.
Cell, 186, 2023
8EM7
DownloadVisualize
BU of 8em7 by Molmil
Cryo-EM structure of LRP2 at pH 5.2
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Beenken, A, Cerutti, G, Fitzpatrick, A.W, Barasch, J, Shapiro, L.
Deposit date:2022-09-27
Release date:2023-02-08
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structures of LRP2 reveal a molecular machine for endocytosis.
Cell, 186, 2023
6POL
DownloadVisualize
BU of 6pol by Molmil
Crystal structure of the human NELL1 EGF1-3-Robo3 FN1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Wang, J, Pak, J.S, Ozkan, E.
Deposit date:2019-07-04
Release date:2020-05-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance.
Nat Commun, 11, 2020
2W86
DownloadVisualize
BU of 2w86 by Molmil
Crystal structure of fibrillin-1 domains cbEGF9hyb2cbEGF10, calcium saturated form
Descriptor: CALCIUM ION, FIBRILLIN-1, IODIDE ION
Authors:Jensen, S.A, Iqbal, S, Lowe, E.D, Redfield, C, Handford, P.A.
Deposit date:2009-01-09
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and Interdomain Interactions of a Hybrid Domain: A Disulphide-Rich Module of the Fibrillin/Ltbp Superfamily of Matrix Proteins.
Structure, 17, 2009
6POG
DownloadVisualize
BU of 6pog by Molmil
Crystal structure of the NELL2 EGF1-6-Robo3 FN1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Wang, J, Pak, J.S, Ozkan, E.
Deposit date:2019-07-03
Release date:2020-05-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.755 Å)
Cite:NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance.
Nat Commun, 11, 2020
7PFP
DownloadVisualize
BU of 7pfp by Molmil
Full-length cryo-EM structure of the native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B.
Deposit date:2021-08-11
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
7Q3N
DownloadVisualize
BU of 7q3n by Molmil
Cryo-EM of the complex between human uromodulin (UMOD)/Tamm-Horsfall protein (THP) and the FimH lectin domain from uropathogenic E. coli
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Type 1 fimbiral adhesin FimH, ...
Authors:Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B.
Deposit date:2021-10-28
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
5MWB
DownloadVisualize
BU of 5mwb by Molmil
Human Notch-2 EGF11-13
Descriptor: CALCIUM ION, Neurogenic locus notch homolog protein 2, alpha-L-fucopyranose, ...
Authors:Suckling, R.J, Handford, P.A, Lea, S.M.
Deposit date:2017-01-18
Release date:2017-06-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017

 

12>

217705

數據於2024-03-27公開中

PDB statisticsPDBj update infoContact PDBjnumon