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8B3Z
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BU of 8b3z by Molmil
SigE N-terminal Domain
Descriptor: RNA polymerase sigma factor
Authors:Evans, N.J, Isaacson, R.L, Collins, K.M, Camp, A.H.
Deposit date:2022-09-18
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural Analysis of Bacillus subtilis Sigma Factors.
Microorganisms, 11, 2023
5OR5
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BU of 5or5 by Molmil
NMR structure of the complex formed by an engineered region 2 of sigmaE in complex with GTAAAA
Descriptor: DNA (5'-D(*GP*TP*AP*AP*AP*A)-3'), ECF RNA polymerase sigma-E factor,ECF RNA polymerase sigma factor SigW,ECF RNA polymerase sigma-E factor
Authors:Campagne, S, Vorholt, J.A, Allain, F.H.
Deposit date:2017-08-15
Release date:2018-06-27
Last modified:2019-07-10
Method:SOLUTION NMR
Cite:Engineered promoter selectivity of an ECF sigma factor
Not published
3MZY
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BU of 3mzy by Molmil
The Crystal Structure of the RNA polymerase sigma-H factor from Fusobacterium nucleatum to 2.5A
Descriptor: RNA polymerase sigma-H factor
Authors:Stein, A.J, Chhor, G, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-05-13
Release date:2010-06-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Crystal Structure of the RNA polymerase sigma-H factor from Fusobacterium nucleatum to 2.5A
To be Published
2O7G
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BU of 2o7g by Molmil
Crystal structure of the Pribnow Box recognition region of SigC from Mycobacterium tuberculosis
Descriptor: Probable RNA polymerase sigma-C factor, SULFATE ION
Authors:Thakur, K.G, Joshi, A.M, Gopal, B.
Deposit date:2006-12-11
Release date:2006-12-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and biophysical studies on two promoter recognition domains of the extra-cytoplasmic function sigma factor sigma(C) from Mycobacterium tuberculosis.
J.Biol.Chem., 282, 2007
1H3L
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BU of 1h3l by Molmil
N-terminal fragment of SigR from Streptomyces coelicolor
Descriptor: RNA POLYMERASE SIGMA FACTOR
Authors:Li, W, Stevenson, C.E.M, Burton, N, Jakimowicz, P, Paget, M.S.B, Buttner, M.J, Lawson, D.M, Kleanthous, C.
Deposit date:2002-09-10
Release date:2002-10-03
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (2.375 Å)
Cite:Identification and Structure of the Anti-Sigma Factor-Binding Domain of the Disulfide-Stress Regulated Sigma Factor Sigma(R) from Streptomyces Coelicolor
J.Mol.Biol., 323, 2002
4LUP
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BU of 4lup by Molmil
Crystal structure of the complex formed by region of E. coli sigmaE bound to its -10 element non template strand
Descriptor: 1,2-ETHANEDIOL, RNA polymerase sigma factor, region 2 of sigmaE of E. coli
Authors:Campagne, S, Marsh, M.E, Vorholt, J.A.V, Allain, F.H.-T, Capitani, G.
Deposit date:2013-07-25
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural basis for -10 promoter element melting by environmentally induced sigma factors.
Nat.Struct.Mol.Biol., 21, 2014
4CXF
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BU of 4cxf by Molmil
Structure of CnrH in complex with the cytosolic domain of CnrY
Descriptor: CHLORIDE ION, CNRY, RNA POLYMERASE SIGMA FACTOR CNRH, ...
Authors:Maillard, A.P, Girard, E, Ziani, W, Petit-Hartlein, I, Kahn, R, Coves, J.
Deposit date:2014-04-07
Release date:2014-04-30
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Crystal Structure of the Anti-Sigma Factor Cnry in Complex with the Sigma Factor Cnrh Shows a New Structural Class of Anti- Sigma Factors Targeting Extracytoplasmic-Function Sigma Factors.
J.Mol.Biol., 426, 2014
2Z2S
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BU of 2z2s by Molmil
Crystal Structure of Rhodobacter sphaeroides SigE in complex with the anti-sigma ChrR
Descriptor: Anti-Sigma factor ChrR, transcriptional activator ChrR, RpoE, ...
Authors:Darst, S.A, Campbell, E.A.
Deposit date:2007-05-26
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria.
Mol.Cell, 27, 2007
2Q1Z
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BU of 2q1z by Molmil
Crystal Structure of Rhodobacter sphaeroides SigE in complex with the anti-sigma ChrR
Descriptor: Anti-Sigma factor ChrR, transcriptional activator ChrR, RpoE, ...
Authors:Campbell, E.A, Darst, S.A.
Deposit date:2007-05-25
Release date:2007-09-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria.
Mol.Cell, 27, 2007
7QH5
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BU of 7qh5 by Molmil
The crystal structure of the sigma factor SigG1 from Streptomyces tsukubaensis NRRL18488
Descriptor: GLYCEROL, RNA polymerase sigma factor
Authors:Lourenco, F, Leite, J.P, Gales, L.
Deposit date:2021-12-10
Release date:2022-12-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of Streptomyces tsukubaensis sigma factor SigG1 and anti-sigma RsfG.
J.Struct.Biol., 215, 2023
5WUQ
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BU of 5wuq by Molmil
Crystal structure of SigW in complex with its anti-sigma RsiW, a zinc binding form
Descriptor: Anti-sigma-W factor RsiW, ECF RNA polymerase sigma factor SigW, ZINC ION
Authors:Devkota, S.R, Kwon, E, Ha, S.C, Kim, D.Y.
Deposit date:2016-12-20
Release date:2017-03-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into the regulation of Bacillus subtilis SigW activity by anti-sigma RsiW
PLoS ONE, 12, 2017
5WUR
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BU of 5wur by Molmil
Crystal structure of SigW in complex with its anti-sigma RsiW, an oxdized form
Descriptor: Anti-sigma-W factor RsiW, ECF RNA polymerase sigma factor SigW
Authors:Devkota, S.R, Kwon, E, Ha, S.C, Kim, D.Y.
Deposit date:2016-12-20
Release date:2017-03-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into the regulation of Bacillus subtilis SigW activity by anti-sigma RsiW
PLoS ONE, 12, 2017
5XE7
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BU of 5xe7 by Molmil
Crystal structure of Mycobacterium tuberculosis extracytoplasmic function sigma factor SigJ
Descriptor: ECF RNA polymerase sigma factor SigJ
Authors:Goutam, K, Gopal, B.
Deposit date:2017-04-01
Release date:2017-07-19
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.162 Å)
Cite:The fused SnoaL_2 domain in the Mycobacterium tuberculosis sigma factor sigma J modulates promoter recognition
Nucleic Acids Res., 45, 2017
7LQ4
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Rr (RsiG)2-(c-di-GMP)2-WhiG complex
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), RsiG, WhiG
Authors:Schumacher, M.A, Brennan, R.G.
Deposit date:2021-02-12
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Evolution of a sigma-(c-di-GMP)-anti-sigma switch.
Proc.Natl.Acad.Sci.USA, 118, 2021
4NQW
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BU of 4nqw by Molmil
Structure of Mycobacterium tuberculosis extracytoplasmic function sigma factor SigK in complex with the cytosolic domain of its cognate anti-sigma factor RskA
Descriptor: Anti-sigma-K factor RskA, CADMIUM ION, ECF RNA polymerase sigma factor SigK
Authors:Shukla, J.K, Gopal, B.
Deposit date:2013-11-25
Release date:2014-01-22
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the redox sensitivity of the Mycobacterium tuberculosis SigK-RskA sigma-anti-sigma complex
Acta Crystallogr.,Sect.D, 70, 2014
6DXO
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BU of 6dxo by Molmil
1.8 A structure of RsbN-BldN complex.
Descriptor: BldN, RNA polymerase ECF-subfamily sigma factor
Authors:Schumacher, M.A.
Deposit date:2018-06-29
Release date:2018-07-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of the RsbN-sigma BldN complex from Streptomyces venezuelae defines a new structural class of anti-sigma factor.
Nucleic Acids Res., 46, 2018
5UXX
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BU of 5uxx by Molmil
Co-crystal structure of the sigma factor RpoE in complex with the anti-sigma factor NepR from Bartonella quintana
Descriptor: Anti-sigma factor NepR, RNA polymerase sigma factor, SULFATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-02-23
Release date:2018-02-28
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Co-crystal structure of the sigma factor RpoE in complex with the anti-sigma factor NepR from Bartonella quintana
to be published
1SMY
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BU of 1smy by Molmil
Structural basis for transcription regulation by alarmone ppGpp
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I, Patlan, V, Sekine, S, Vassylyeva, M.N, Hosaka, T, Ochi, K, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-03-10
Release date:2004-05-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for transcription regulation by alarmone ppGpp
Cell(Cambridge,Mass.), 117, 2004
4Q4Z
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BU of 4q4z by Molmil
Thermus thermophilus RNA polymerase de novo transcription initiation complex
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ADENOSINE-5'-TRIPHOSPHATE, DNA (25-MER), ...
Authors:Murakami, K.S.
Deposit date:2014-04-15
Release date:2014-07-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of transcription initiation by bacterial RNA polymerase holoenzyme.
J.Biol.Chem., 289, 2014
8U3B
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BU of 8u3b by Molmil
Cryo-EM structure of E. coli NarL-transcription activation complex at 3.2A
Descriptor: DNA (69-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Kompaniiets, D, Wang, D.
Deposit date:2023-09-07
Release date:2024-01-17
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Structural basis for transcription activation by the nitrate-responsive regulator NarL.
Nucleic Acids Res., 52, 2024
7ZF2
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BU of 7zf2 by Molmil
Protomeric substructure from an octameric assembly of M. tuberculosis RNA polymerase in complex with sigma-b initiation factor
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Trapani, S, Bron, P, Lai Kee Him, J, Brodolin, K, Morichaud, Z, Vishwakarma, R.
Deposit date:2022-03-31
Release date:2023-02-08
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization.
Nat Commun, 14, 2023
8AD1
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BU of 8ad1 by Molmil
RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Dey, S, Weixlbaumer, A.
Deposit date:2022-07-07
Release date:2022-10-19
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
3DXJ
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BU of 3dxj by Molmil
Crystal structure of thermus thermophilus rna polymerase holoenzyme in complex with the antibiotic myxopyronin
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M, ...
Authors:Das, K, Arnold, E.
Deposit date:2008-07-24
Release date:2008-10-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:The RNA polymerase "switch region" is a target for inhibitors.
Cell(Cambridge,Mass.), 135, 2008
3EQL
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BU of 3eql by Molmil
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic myxopyronin
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I.
Deposit date:2008-09-30
Release date:2008-10-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Transcription inactivation through local refolding of the RNA polymerase structure.
Nature, 457, 2009
8DY7
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BU of 8dy7 by Molmil
Streptomyces venezuelae RNAP transcription open promoter complex with WhiA and WhiB transcription factors
Descriptor: DNA (71-MER), DNA (78-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lilic, M, Campbell, E.A.
Deposit date:2022-08-03
Release date:2023-03-01
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Proc.Natl.Acad.Sci.USA, 120, 2023

217705

數據於2024-03-27公開中

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