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6HCE
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BU of 6hce by Molmil
Crystal structure of chicken riboflavin binding protein in "Apo" form at 2.5 A resolution
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Loch, J.I, Lipowska, J, Lewinski, K.
Deposit date:2018-08-14
Release date:2018-08-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of chicken riboflavin binding protein in "Apo" form at 2.5 A resolution
To Be Published
7PGK
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BU of 7pgk by Molmil
HHIP-N, the N-terminal domain of the Hedgehog-Interacting Protein (HHIP), in complex with glycosaminoglycan mimic SOS
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Hedgehog-interacting protein
Authors:Griffiths, S.C, Schwab, R.A, El Omari, K, Bishop, B, Iverson, E.J, Malinuskas, T, Dubey, R, Qian, M, Covey, D.F, Gilbert, R.J.C, Rohatgi, R, Siebold, C.
Deposit date:2021-08-14
Release date:2021-12-15
Last modified:2021-12-22
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling.
Nat Commun, 12, 2021
7PGL
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BU of 7pgl by Molmil
HHIP-N, the N-terminal domain of the Hedgehog-Interacting Protein (HHIP), apo-form
Descriptor: Hedgehog-interacting protein
Authors:Griffiths, S.C, Schwab, R.A, El Omari, K, Bishop, B, Iverson, E.J, Malinuskas, T, Dubey, R, Qian, M, Covey, D.F, Gilbert, R.J.C, Rohatgi, R, Siebold, C.
Deposit date:2021-08-14
Release date:2021-12-15
Last modified:2021-12-22
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling.
Nat Commun, 12, 2021
5EJN
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BU of 5ejn by Molmil
Crystal structure of Juno, the mammalian egg receptor for sperm Izumo1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Sperm-egg fusion protein Juno
Authors:Nishimura, K, Han, L, Jovine, L.
Deposit date:2015-11-02
Release date:2016-02-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Divergent evolution of vitamin B9 binding underlies Juno-mediated adhesion of mammalian gametes.
Curr.Biol., 26, 2016
5F4Q
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BU of 5f4q by Molmil
Crystal structure of the human egg surface protein Juno
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
Authors:Aydin, H, Sultana, A, Lee, J.E.
Deposit date:2015-12-03
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex.
Nature, 534, 2016
4KN0
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BU of 4kn0 by Molmil
Human folate receptor beta (FOLR2) in complex with the antifolate methotrexate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Folate receptor beta, ...
Authors:Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KM7
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BU of 4km7 by Molmil
Human folate receptor alpha (FOLR1) at acidic pH, triclinic form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Folate receptor alpha, POTASSIUM ION
Authors:Kovach, A.R, Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KM6
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BU of 4km6 by Molmil
Human folate receptor alpha (FOLR1) at acidic pH, orthorhombic form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Folate receptor alpha
Authors:Singh, M, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KN1
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BU of 4kn1 by Molmil
Human folate receptor beta (FOLR2) in complex with the antifolate aminopterin
Descriptor: Aminopterin, CHLORIDE ION, Folate receptor beta, ...
Authors:Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KMX
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BU of 4kmx by Molmil
Human folate receptor alpha (FOLR1) at acidic pH, hexagonal form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KMY
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BU of 4kmy by Molmil
Human folate receptor beta (FOLR2) at neutral pH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Folate receptor beta, POTASSIUM ION
Authors:Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.795 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KN2
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BU of 4kn2 by Molmil
Human folate receptor beta (FOLR2) in complex with antifolate pemetrexed
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, CHLORIDE ION, ...
Authors:Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KMZ
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BU of 4kmz by Molmil
Human folate receptor beta (FOLR2) in complex with the folate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, FOLIC ACID, ...
Authors:Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LRH
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BU of 4lrh by Molmil
Crystal structure of human folate receptor alpha in complex with folic acid
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, Folate receptor alpha
Authors:Ke, J, Chen, C, Zhou, X.E, Yi, W, Brunzelle, J.S, Li, J, Young, E.-L, Xu, H.E, Melcher, K.
Deposit date:2013-07-19
Release date:2013-07-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for molecular recognition of folic acid by folate receptors.
Nature, 500, 2013
5IZQ
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BU of 5izq by Molmil
Crystal structure of human folate receptor alpha in complex with novel antifolate AGF183
Descriptor: Folate receptor alpha, N-(4-{[2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)ethyl]amino}benzene-1-carbonyl)-L-glutamic acid
Authors:Ke, J, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
Deposit date:2016-03-25
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor alpha and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.
J.Med.Chem., 59, 2016
5JKB
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BU of 5jkb by Molmil
Crystal structure of human JUNO (crystal form 2)
Descriptor: CHLORIDE ION, Sperm-egg fusion protein Juno
Authors:Ohto, U, Ishida, H, Shimizu, T.
Deposit date:2016-04-26
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
5JKA
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BU of 5jka by Molmil
Crystal structure of human JUNO (crystal form 1)
Descriptor: CHLORIDE ION, Sperm-egg fusion protein Juno, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Ohto, U, Ishida, H, Shimizu, T.
Deposit date:2016-04-26
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
5JYJ
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BU of 5jyj by Molmil
Crystal structure of mouse JUNO
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sperm-egg fusion protein Juno
Authors:Kato, K, Nishimasu, H, Morita, J, Ishitani, R, Nureki, O.
Deposit date:2016-05-14
Release date:2017-05-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the egg IZUMO1 receptor JUNO
To Be Published
5F4E
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BU of 5f4e by Molmil
Crystal structure of the human sperm Izumo1 and egg Juno complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
Authors:Aydin, H, Sultana, A, Lee, J.E.
Deposit date:2015-12-03
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex.
Nature, 534, 2016
5JKC
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BU of 5jkc by Molmil
Crystal structure of human IZUMO1-JUNO complex (crystal form 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Izumo sperm-egg fusion protein 1, ...
Authors:Ohto, U, Ishida, H, Shimizu, T.
Deposit date:2016-04-26
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
5JKD
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BU of 5jkd by Molmil
Crystal structure of human IZUMO1-JUNO complex (crystal form 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Izumo sperm-egg fusion protein 1, ...
Authors:Ohto, U, Ishida, H, Shimizu, T.
Deposit date:2016-04-26
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
5JKE
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BU of 5jke by Molmil
Crystal structure of human IZUMO1-JUNO complex (crystal form 3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Izumo sperm-egg fusion protein 1, ...
Authors:Ohto, U, Ishida, H, Shimizu, T.
Deposit date:2016-04-26
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016

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數據於2024-03-27公開中

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