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5GUP
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BU of 5gup by Molmil
Cryo-EM structure of mammalian respiratory supercomplex I1III2IV1
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ...
Authors:Gu, J, Wu, M, Guo, R, Yang, M.
Deposit date:2016-08-30
Release date:2017-03-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of Mammalian Respiratory Supercomplex I1III2IV1
Cell, 167, 2016
3L73
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BU of 3l73 by Molmil
Cytochrome BC1 complex from chicken with triazolone inhibitor
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 4-[7-(3,3-dimethylbut-1-yn-1-yl)naphthalen-1-yl]-5-methoxy-2-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one, CARDIOLIPIN, ...
Authors:Huang, L, Berry, E.A.
Deposit date:2009-12-27
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Famoxadone and related inhibitors bind like methoxy acrylate inhibitors in the Qo site of the BC1 compl and fix the rieske iron-sulfur protein in a positio close to but distinct from that seen with stigmatellin and other "DISTAL" Qo inhibitors.
To be Published
7TZ6
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BU of 7tz6 by Molmil
Structure of mitochondrial bc1 in complex with ck-2-68
Descriptor: 7-chloranyl-3-methyl-2-[4-[[4-(trifluoromethyloxy)phenyl]methyl]phenyl]-1~{H}-quinolin-4-one, Cytochrome b, Cytochrome b-c1 complex subunit 1, ...
Authors:Xia, D, Esser, L, Zhou, F, Huang, R.
Deposit date:2022-02-15
Release date:2023-02-22
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc 1 complexes.
J.Biol.Chem., 299, 2023
1BGY
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BU of 1bgy by Molmil
CYTOCHROME BC1 COMPLEX FROM BOVINE
Descriptor: CYTOCHROME BC1 COMPLEX, FE2/S2 (INORGANIC) CLUSTER, HEME C, ...
Authors:Iwata, S, Lee, J.W, Okada, K, Lee, J.K, Iwata, M, Ramaswamy, S, Jap, B.K.
Deposit date:1998-06-02
Release date:1999-01-06
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex.
Science, 281, 1998
3TGU
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BU of 3tgu by Molmil
Cytochrome bc1 complex from chicken with pfvs-designed moa inhibitor bound
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, Coenzyme Q10, ...
Authors:Huang, L.-S, Yang, G.-F, Berry, E.A.
Deposit date:2011-08-17
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex.
J.Am.Chem.Soc., 134, 2012
4U3F
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BU of 4u3f by Molmil
Cytochrome bc1 complex from chicken with designed inhibitor bound
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CARDIOLIPIN, ...
Authors:Huang, L.-S, Zhu, X.-L, Yang, G.F, Berry, E.A.
Deposit date:2014-07-21
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2312 Å)
Cite:Rational Design of Highly Potent and Slow-Binding Cytochrome bc1 Inhibitor as Fungicide by Computational Substitution Optimization
Sci Rep, 5, 2015
1EZV
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BU of 1ezv by Molmil
STRUCTURE OF THE YEAST CYTOCHROME BC1 COMPLEX CO-CRYSTALLIZED WITH AN ANTIBODY FV-FRAGMENT
Descriptor: 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, CYTOCHROME B, CYTOCHROME C1, ...
Authors:Hunte, C, Koepke, J, Lange, C, Rossmanith, T, Michel, H.
Deposit date:2000-05-12
Release date:2001-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.
Structure Fold.Des., 8, 2000
8Q1B
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BU of 8q1b by Molmil
III2-IV1 respiratory supercomplex from S. pombe
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CALCIUM ION, CARDIOLIPIN, ...
Authors:Moe, A, Brzezinski, P.
Deposit date:2023-07-31
Release date:2023-11-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of the S. pombe III-IV-cyt c supercomplex.
Proc.Natl.Acad.Sci.USA, 120, 2023
2YBB
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BU of 2ybb by Molmil
Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (EMD-1876)
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, CARDIOLIPIN, ...
Authors:Althoff, T, Mills, D.J, Popot, J.-L, Kuehlbrandt, W.
Deposit date:2011-03-02
Release date:2011-10-19
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (19 Å)
Cite:Arrangement of Electron Transport Chain Components in Bovine Mitochondrial Supercomplex I(1)III(2)Iv(1).
Embo J., 30, 2011
6NHG
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BU of 6nhg by Molmil
Rhodobacter sphaeroides Mitochondrial respiratory chain complex
Descriptor: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, ...
Authors:Xia, D, Zhou, F, Esser, L.
Deposit date:2018-12-21
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of bacterial cytochromebc1in complex with azoxystrobin reveals a conformational switch of the Rieske iron-sulfur protein subunit.
J.Biol.Chem., 294, 2019
6FO6
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BU of 6fo6 by Molmil
CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial inhibitor SCR0911
Descriptor: 7-methoxy-3-methyl-2-[5-[4-(trifluoromethyloxy)phenyl]pyridin-3-yl]quinolin-4-ol, Cytochrome b, Cytochrome b-c1 complex subunit 1, ...
Authors:Johnson, R.M, Amporndanai, K, O'Neill, P.M, Fishwick, C.W.G, Jamson, A.H, Rawson, S.D, Hasnain, S.S, Antonyuk, S.V, Muench, S.P.
Deposit date:2018-02-06
Release date:2018-02-28
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery.
IUCrJ, 5, 2018
4PD4
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BU of 4pd4 by Molmil
Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action
Descriptor: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, ...
Authors:Birth, D, Kao, W.-C, Hunte, C.
Deposit date:2014-04-17
Release date:2014-06-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action.
Nat Commun, 5, 2014
5NMI
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BU of 5nmi by Molmil
Cytochrome bc1 bound to the inhibitor MJM170
Descriptor: (4aS)-2-methyl-3-(4-phenoxyphenyl)-5,6,7,8-tetrahydroquinolin-4(4aH)-one, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ARG-ASN-TRP-VAL-PRO-THR-ALA-GLN-LEU-TRP-GLY-ALA-VAL-GLY-ALA-VAL-GLY-LEU-VAL-SER-ALA-THR, ...
Authors:Capper, N.J, Antonyuk, S.V, Hasnain, S.S.
Deposit date:2017-04-05
Release date:2017-06-14
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections.
Sci Rep, 6, 2016
1SQV
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BU of 1sqv by Molmil
Crystal Structure Analysis of Bovine Bc1 with UHDBT
Descriptor: 6-HYDROXY-5-UNDECYL-1,3-BENZOTHIAZOLE-4,7-DIONE, Cytochrome b, Cytochrome c1, ...
Authors:Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D.
Deposit date:2004-03-19
Release date:2005-09-06
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex.
J.Mol.Biol., 341, 2004
1SQX
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BU of 1sqx by Molmil
Crystal Structure Analysis of Bovine Bc1 with Stigmatellin A
Descriptor: Cytochrome b, Cytochrome c1, heme protein, ...
Authors:Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D.
Deposit date:2004-03-21
Release date:2005-09-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex.
J.Mol.Biol., 341, 2004
1BCC
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BU of 1bcc by Molmil
CYTOCHROME BC1 COMPLEX FROM CHICKEN
Descriptor: 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Zhang, Z, Huang, L, Shulmeister, V.M, Chi, Y.-I, Kim, K.K, Hung, L.-W, Crofts, A.R, Berry, E.A, Kim, S.-H.
Deposit date:1998-03-23
Release date:1998-08-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Electron transfer by domain movement in cytochrome bc1.
Nature, 392, 1998
1BE3
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BU of 1be3 by Molmil
CYTOCHROME BC1 COMPLEX FROM BOVINE
Descriptor: CYTOCHROME BC1 COMPLEX, FE2/S2 (INORGANIC) CLUSTER, HEME C, ...
Authors:Iwata, S, Lee, J.W, Okada, K, Lee, J.K, Iwata, M, Ramaswamy, S, Jap, B.K.
Deposit date:1998-05-19
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex.
Science, 281, 1998
5KLV
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BU of 5klv by Molmil
Structure of bos taurus cytochrome bc1 with fenamidone inhibited
Descriptor: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3-(phenylamino)-3,5-dihydro-4H-imidazol-4-one, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ...
Authors:Xia, D, Esser, L, Zhou, F, Zhou, Y, Xiao, Y, Tang, W.K, Yu, C.A, Qin, Z.
Deposit date:2016-06-25
Release date:2016-10-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.652 Å)
Cite:Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
6T0B
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BU of 6t0b by Molmil
The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CALCIUM ION, CARDIOLIPIN, ...
Authors:Marechal, A, Pinotsis, N, Hartley, A.
Deposit date:2019-10-02
Release date:2020-04-22
Last modified:2020-05-06
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes.
Proc.Natl.Acad.Sci.USA, 117, 2020
6T15
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BU of 6t15 by Molmil
The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CARDIOLIPIN, COPPER (II) ION, ...
Authors:Marechal, A, Pinotsis, N, Hartley, A.
Deposit date:2019-10-03
Release date:2020-04-22
Last modified:2020-05-06
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes.
Proc.Natl.Acad.Sci.USA, 117, 2020
5OKD
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BU of 5okd by Molmil
Crystal structure of bovine Cytochrome bc1 in complex with inhibitor SCR0911.
Descriptor: 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
Authors:Amporndanai, K, O'Neill, P.M, Hasnain, S.S, Antonyuk, S.V.
Deposit date:2017-07-25
Release date:2018-02-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery.
IUCrJ, 5, 2018
2FYU
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BU of 2fyu by Molmil
Crystal structure of bovine heart mitochondrial bc1 with jg144 inhibitor
Descriptor: (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE, Cytochrome b, Cytochrome c1, ...
Authors:Xia, D, Esser, L.
Deposit date:2006-02-08
Release date:2006-08-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Surface-modulated motion switch: Capture and release of iron-sulfur protein in the cytochrome bc1 complex.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2A06
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BU of 2a06 by Molmil
Bovine cytochrome bc1 complex with stigmatellin bound
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, AZIDE ION, CARDIOLIPIN, ...
Authors:Huang, L.S, Cobessi, D, Tung, E.Y, Berry, E.A.
Deposit date:2005-06-16
Release date:2005-06-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding of the Respiratory Chain Inhibitor Antimycin to the Mitochondrial bc(1) Complex: A New Crystal Structure Reveals an Altered Intramolecular Hydrogen-bonding Pattern.
J.Mol.Biol., 351, 2005
6XVF
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BU of 6xvf by Molmil
Crystal structure of bovine cytochrome bc1 in complex with tetrahydro-quinolone inhibitor JAG021
Descriptor: 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
Authors:Amporndanai, K, Hasnain, S.S, Antonyuk, S.V.
Deposit date:2020-01-21
Release date:2020-07-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites.
Front Cell Infect Microbiol, 10, 2020
5LUF
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BU of 5luf by Molmil
Cryo-EM of bovine respirasome
Descriptor: COPPER (II) ION, Cytochrome b, Cytochrome b-c1 complex subunit 1, ...
Authors:Sousa, J.S, Mills, D.J, Vonck, J, Kuehlbrandt, W.
Deposit date:2016-09-08
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Functional asymmetry and electron flow in the bovine respirasome.
Elife, 5, 2016

217705

數據於2024-03-27公開中

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