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2MUX
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BU of 2mux by Molmil
SUMO2 non-covalently interacts with USP25 and downregulates its activity
Descriptor: Ubiquitin carboxyl-terminal hydrolase 25
Authors:Shi, L, Zhang, N, Wen, Y.
Deposit date:2014-09-18
Release date:2016-04-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:SUMO2 non-covalently interacts with USP25 and downregulates its activity
To be Published
1YX4
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BU of 1yx4 by Molmil
Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition
Descriptor: 26S proteasome non-ATPase regulatory subunit 4
Authors:Wang, Q, Young, P, Walters, K.J.
Deposit date:2005-02-19
Release date:2005-04-19
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition
J.Mol.Biol., 348, 2005
2KLZ
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BU of 2klz by Molmil
Solution Structure of the Tandem UIM Domain of Ataxin-3 Complexed with Ubiquitin
Descriptor: Ataxin-3
Authors:Zhou, C, Song, A, Lin, D, Hu, H.
Deposit date:2009-07-12
Release date:2010-07-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution Structure of the Tandem UIM Domain of Ataxin-3 Complexed with Ubiquitin
To be Published
1O06
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BU of 1o06 by Molmil
Crystal structure of the Vps27p Ubiquitin Interacting Motif (UIM)
Descriptor: Vacuolar protein sorting-associated protein VPS27, ZINC ION
Authors:Fisher, R.D, Wang, B, Alam, S.L, Higginson, D.S, Rich, R, Myszka, D, Sundquist, W.I, Hill, C.P.
Deposit date:2003-02-20
Release date:2003-07-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure and ubiquitin binding of the ubiquitin-interacting motif.
J.Biol.Chem., 278, 2003
1P9C
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BU of 1p9c by Molmil
NMR solution structure of the C-terminal ubiquitin-interacting motif of the proteasome subunit S5a
Descriptor: 26S proteasome non-ATPase regulatory subunit 4
Authors:Mueller, T.D, Feigon, J.
Deposit date:2003-05-10
Release date:2003-10-07
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural determinants for the binding of ubiquitin-like domains to the proteasome.
Embo J., 22, 2003
1Q0V
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BU of 1q0v by Molmil
Solution Structure of Tandem UIMs of Vps27
Descriptor: hydrophilic protein; has cysteine rich putative zinc finger essential for function; Vps27p
Authors:Swanson, K.A, Kang, R.S, Stamenova, S.D, Hicke, L, Radhakrishnan, I.
Deposit date:2003-07-17
Release date:2003-12-23
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation.
Embo J., 22, 2003
5O71
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BU of 5o71 by Molmil
Crystal structure of human USP25
Descriptor: Ubiquitin carboxyl-terminal hydrolase 25
Authors:Reverter, D, Liu, B.
Deposit date:2017-06-07
Release date:2018-06-20
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (3.283 Å)
Cite:A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25.
Nat Commun, 9, 2018
6WJD
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BU of 6wjd by Molmil
SA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A
Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
Authors:Chen, X, Walters, K.J.
Deposit date:2020-04-13
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 28, 2020
1UEL
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BU of 1uel by Molmil
Solution structure of ubiquitin-like domain of hHR23B complexed with ubiquitin-interacting motif of proteasome subunit S5a
Descriptor: 26S proteasome non-ATPase regulatory subunit 4, UV excision repair protein RAD23 homolog B
Authors:Fujiwara, K, Tenno, T, Jee, J.G, Sugasawa, K, Ohki, I, Kojima, C, Tochio, H, Hiroaki, H, Hanaoka, H, Shirakawa, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-19
Release date:2004-02-10
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of the Ubiquitin-interacting Motif of S5a Bound to the Ubiquitin-like Domain of HR23B
J.Biol.Chem., 279, 2004
8CVT
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BU of 8cvt by Molmil
Human 19S-20S proteasome, state SD2
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Zhao, J.
Deposit date:2022-05-18
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
5GJQ
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BU of 5gjq by Molmil
Structure of the human 26S proteasome bound to USP14-UbAl
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Huang, X.L, Luan, B, Wu, J.P, Shi, Y.G.
Deposit date:2016-07-01
Release date:2016-08-17
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:An atomic structure of the human 26S proteasome.
Nat. Struct. Mol. Biol., 23, 2016
5GJR
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BU of 5gjr by Molmil
An atomic structure of the human 26S proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Huang, X.L, Luan, B, Wu, J.P, Shi, Y.G.
Deposit date:2016-07-01
Release date:2016-09-07
Last modified:2019-10-09
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:An atomic structure of the human 26S proteasome.
Nat. Struct. Mol. Biol., 23, 2016
5L4K
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BU of 5l4k by Molmil
The human 26S proteasome lid
Descriptor: 26S proteasome complex subunit DSS1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
Authors:Schweitzer, A, Aufderheide, A, Rudack, T, Beck, F.
Deposit date:2016-05-25
Release date:2016-09-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure of the human 26S proteasome at a resolution of 3.9 angstrom.
Proc.Natl.Acad.Sci.USA, 113, 2016
1YX5
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BU of 1yx5 by Molmil
Solution Structure of S5a UIM-1/Ubiquitin Complex
Descriptor: 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin
Authors:Wang, Q, Young, P, Walters, K.J.
Deposit date:2005-02-19
Release date:2005-04-19
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure of S5a Bound to Monoubiquitin Provides a Model for Polyubiquitin Recognition
J.Mol.Biol., 348, 2005
1YX6
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BU of 1yx6 by Molmil
Solution Structure of S5a UIM-2/Ubiquitin Complex
Descriptor: 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin
Authors:Wang, Q, Young, P, Walters, K.J.
Deposit date:2005-02-19
Release date:2005-04-19
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure of S5a Bound to Monoubiquitin Provides a Model for Polyubiquitin Recognition
J.Mol.Biol., 348, 2005
5LN3
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BU of 5ln3 by Molmil
The human 26S Proteasome at 6.8 Ang.
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Schweitzer, A, Beck, F, Sakata, E, Unverdorben, P.
Deposit date:2016-08-03
Release date:2017-03-22
Last modified:2017-05-24
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome.
Mol. Cell Proteomics, 16, 2017
5M32
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BU of 5m32 by Molmil
Human 26S proteasome in complex with Oprozomib
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Haselbach, D, Schrader, J, Lambrecht, F, Henneberg, F, Chari, A, Stark, H.
Deposit date:2016-10-14
Release date:2017-07-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs.
Nat Commun, 8, 2017
5IXF
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BU of 5ixf by Molmil
Solution structure of the STAM2 SH3 with AMSH derived peptide complex
Descriptor: STAM-binding protein, Signal transducing adapter molecule 2
Authors:Hologne, M, Cantrelle, F.X, Trivelli, X, Walker, O.
Deposit date:2016-03-23
Release date:2016-12-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR Reveals the Interplay among the AMSH SH3 Binding Motif, STAM2, and Lys63-Linked Diubiquitin.
J.Mol.Biol., 428, 2016
2KDF
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BU of 2kdf by Molmil
NMR structure of minor S5a (196-306):K48 linked diubiquitin species
Descriptor: 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin
Authors:Zhang, N, Wang, Q, Ehlinger, A, Randles, L, Lary, J.W, Kang, Y, Haririnia, A, Cole, J.L, Fushman, D, Walters, K.J.
Deposit date:2009-01-06
Release date:2009-09-01
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13.
Mol.Cell, 35, 2009
2KDE
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BU of 2kde by Molmil
NMR structure of major S5a (196-306):K48 linked diubiquitin species
Descriptor: 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin
Authors:Zhang, N, Wang, Q, Ehlinger, A, Randles, L, Lary, J.W, Kang, Y, Haririnia, A, Cole, J.L, Fushman, D, Walters, K.J.
Deposit date:2009-01-06
Release date:2009-09-01
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13.
Mol.Cell, 35, 2009
6EPC
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BU of 6epc by Molmil
Ground state 26S proteasome (GS2)
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ...
Authors:Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R.
Deposit date:2017-10-11
Release date:2018-02-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (12.3 Å)
Cite:In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
6EPD
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BU of 6epd by Molmil
Substrate processing state 26S proteasome (SPS1)
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ...
Authors:Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R.
Deposit date:2017-10-11
Release date:2018-02-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (15.4 Å)
Cite:In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
6EPF
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BU of 6epf by Molmil
Ground state 26S proteasome (GS1)
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ...
Authors:Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R.
Deposit date:2017-10-11
Release date:2018-02-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (11.8 Å)
Cite:In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
6EPE
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BU of 6epe by Molmil
Substrate processing state 26S proteasome (SPS2)
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ...
Authors:Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R.
Deposit date:2017-10-11
Release date:2018-02-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (12.8 Å)
Cite:In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
5T0I
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BU of 5t0i by Molmil
Structural basis for dynamic regulation of the human 26S proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016

 

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數據於2024-03-27公開中

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