1C4R
 
 | | THE STRUCTURE OF THE LIGAND-BINDING DOMAIN OF NEUREXIN 1BETA: REGULATION OF LNS DOMAIN FUNCTION BY ALTERNATIVE SPLICING | | Descriptor: | NEUREXIN-I BETA | | Authors: | Rudenko, G, Nguyen, T, Chelliah, Y, Sudhof, T.C, Deisenhofer, J. | | Deposit date: | 1999-09-28 | | Release date: | 2000-10-04 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The structure of the ligand-binding domain of neurexin Ibeta: regulation of LNS domain function by alternative splicing.
Cell(Cambridge,Mass.), 99, 1999
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7ZC9
 | | Human Pikachurin/EGFLAM C-terminal Laminin-G domain (LG3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Pikachurin, SULFATE ION | | Authors: | Pantalone, S, Forneris, F. | | Deposit date: | 2022-03-26 | | Release date: | 2023-07-19 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.
Sci.Signal., 16, 2023
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2H0B
 | | Crystal Structure of the second LNS/LG domain from Neurexin 1 alpha | | Descriptor: | CALCIUM ION, GLYCEROL, Neurexin-1-alpha | | Authors: | Sheckler, L.R, Henry, L, Sugita, S, Sudhof, T.C, Rudenko, G. | | Deposit date: | 2006-05-14 | | Release date: | 2006-06-20 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structure of the Second LNS/LG Domain from Neurexin 1{alpha}: Ca2+ binding and the effects of alternative splicing
J.Biol.Chem., 281, 2006
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1QU0
 | | CRYSTAL STRUCTURE OF THE FIFTH LAMININ G-LIKE MODULE OF THE MOUSE LAMININ ALPHA2 CHAIN | | Descriptor: | CALCIUM ION, LAMININ ALPHA2 CHAIN, SULFATE ION | | Authors: | Hohenester, E, Tisi, D, Talts, J.F, Timpl, R. | | Deposit date: | 1999-07-05 | | Release date: | 1999-12-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The crystal structure of a laminin G-like module reveals the molecular basis of alpha-dystroglycan binding to laminins, perlecan, and agrin.
Mol.Cell, 4, 1999
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6CW1
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2R1D
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2R1B
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2R16
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3ASI
 | | Alpha-Neurexin-1 ectodomain fragment; LNS5-EGF3-LNS6 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurexin-1-alpha | | Authors: | Tanaka, H, Nogi, T, Yasui, N, Takagi, J. | | Deposit date: | 2010-12-13 | | Release date: | 2011-04-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis for Variant-Specific Neuroligin-Binding by alpha-Neurexin
Plos One, 6, 2011
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3BOD
 | | Structure of mouse beta-neurexin 1 | | Descriptor: | CALCIUM ION, Neurexin-1-alpha | | Authors: | Koehnke, J, Jin, X, Shapiro, L. | | Deposit date: | 2007-12-17 | | Release date: | 2008-03-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structures of beta-Neurexin 1 and beta-Neurexin 2 Ectodomains and Dynamics of Splice Insertion Sequence 4.
Structure, 16, 2008
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3BOP
 | | Structure of mouse beta-neurexin 2D4 | | Descriptor: | beta-Neurexin 2D4 | | Authors: | Koehnke, J, Jin, X, Shapiro, L. | | Deposit date: | 2007-12-17 | | Release date: | 2008-03-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal Structures of beta-Neurexin 1 and beta-Neurexin 2 Ectodomains and Dynamics of Splice Insertion Sequence 4.
Structure, 16, 2008
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3MW4
 | | Crystal structure of beta-neurexin 3 without the splice insert 4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurexin-2-beta, ... | | Authors: | Jin, X, Shapiro, L. | | Deposit date: | 2010-05-05 | | Release date: | 2010-07-28 | | Last modified: | 2021-10-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Splice Form Dependence of beta-Neurexin/Neuroligin Binding Interactions.
Neuron, 67, 2010
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3MW3
 | | Crystal structure of beta-neurexin 2 with the splice insert 4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurexin-2-beta | | Authors: | Jin, X, Shapiro, L. | | Deposit date: | 2010-05-05 | | Release date: | 2010-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Splice Form Dependence of beta-Neurexin/Neuroligin Binding Interactions.
Neuron, 67, 2010
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3MW2
 | | Crystal structure of beta-neurexin 1 with the splice insert 4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Neurexin-1-alpha, PHOSPHATE ION | | Authors: | Jin, X, Shapiro, L. | | Deposit date: | 2010-05-05 | | Release date: | 2010-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Splice Form Dependence of beta-Neurexin/Neuroligin Binding Interactions.
Neuron, 67, 2010
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3SH4
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3SH5
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5Z8Y
 | | Crystal structure of human LRRTM2 in complex with Neurexin 1beta | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Yamagata, A, Fukai, S. | | Deposit date: | 2018-02-01 | | Release date: | 2018-10-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural insights into modulation and selectivity of transsynaptic neurexin-LRRTM interaction.
Nat Commun, 9, 2018
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6PNP
 | | Crystal structure of the splice insert-free neurexin-1 LNS2 domain in complex with neurexophilin-1 | | Descriptor: | Neurexin-1, Neurexophilin-1 | | Authors: | Wilson, S.C, White, K.I, Zhou, Q, Brunger, A.T. | | Deposit date: | 2019-07-02 | | Release date: | 2019-10-09 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Structures of neurexophilin-neurexin complexes reveal a regulatory mechanism of alternative splicing.
Embo J., 38, 2019
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6PNQ
 | | Crystal structure of the SS2A splice insert-containing neurexin-1 LNS2 domain in complex with neurexophilin-1 | | Descriptor: | Neurexin-1, Neurexophilin-1 | | Authors: | Wilson, S.C, White, K.I, Zhou, Q, Brunger, A.T. | | Deposit date: | 2019-07-02 | | Release date: | 2019-10-09 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.947 Å) | | Cite: | Structures of neurexophilin-neurexin complexes reveal a regulatory mechanism of alternative splicing.
Embo J., 38, 2019
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7ML7
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2C5D
 | | Structure of a minimal Gas6-Axl complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN 6 PRECURSOR, ... | | Authors: | Sasaki, T, Knyazev, P.G, Clout, N.J, Cheburkin, Y, Goehring, W, Ullrich, A, Timpl, R, Hohenester, E. | | Deposit date: | 2005-10-26 | | Release date: | 2005-12-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural Basis for Gas6-Axl Signalling.
Embo J., 25, 2006
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7CEC
 | | Structure of alpha6beta1 integrin in complex with laminin-511 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Arimori, T, Miyazaki, N, Takagi, J. | | Deposit date: | 2020-06-22 | | Release date: | 2021-06-23 | | Last modified: | 2021-07-14 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural mechanism of laminin recognition by integrin.
Nat Commun, 12, 2021
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8D1B
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3VKF
 | | Crystal Structure of Neurexin 1beta/Neuroligin 1 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurexin-1-beta, ... | | Authors: | Tanaka, H, Miyazaki, N, Nogi, T, Iwasaki, K, Takagi, J. | | Deposit date: | 2011-11-15 | | Release date: | 2012-08-01 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Higher-order architecture of cell adhesion mediated by polymorphic synaptic adhesion molecules neurexin and neuroligin.
Cell Rep, 2, 2012
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4RA0
 | | An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Kariolis, M.S, Kapur, S, Mathews, I.I, Cochran, J.R. | | Deposit date: | 2014-09-09 | | Release date: | 2014-09-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.07 Å) | | Cite: | An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis.
Nat.Chem.Biol., 10, 2014
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