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2LVW
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BU of 2lvw by Molmil
Solution NMR studies of the dimeric regulatory subunit IlvN of the E.coli Acetohydroxyacid synthase I (AHAS I)
Descriptor: Acetolactate synthase isozyme 1 small subunit
Authors:Karanth, M.N, Sarma, S.P.
Deposit date:2012-07-12
Release date:2013-05-29
Method:SOLUTION NMR
Cite:The coil-to-helix transition in IlvN regulates the allosteric control of Escherichia coli acetohydroxyacid synthase I
Biochemistry, 52, 2013
5YPY
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BU of 5ypy by Molmil
Crystal structure of IlvN. Val-1c
Descriptor: Acetolactate synthase isozyme 1 small subunit, VALINE
Authors:Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B.
Deposit date:2017-11-04
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.966 Å)
Cite:Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 58, 2019
5YUM
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BU of 5yum by Molmil
Crystallographic structures of IlvN.Val/Ile complexes:Conformational selectivity for feedback inhibition of AHASs
Descriptor: Acetolactate synthase isozyme 1 small subunit, COBALT (II) ION, ISOLEUCINE
Authors:Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B.
Deposit date:2017-11-22
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.432 Å)
Cite:Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 58, 2019
5FII
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BU of 5fii by Molmil
Structure of a human aspartate kinase, chorismate mutase and TyrA domain.
Descriptor: PHENYLALANINE, PHENYLALANINE-4-HYDROXYLASE
Authors:Patel, D, Kopec, J, Shrestha, L, Fitzpatrick, F, Pinkas, D, Chaikuad, A, Dixon-Clarke, S, McCorvie, T.J, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W.
Deposit date:2015-09-25
Release date:2016-03-30
Last modified:2016-10-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Ligand-Dependent Dimerization of Phenylalanine Hydroxylase Regulatory Domain.
Sci.Rep., 6, 2016
5V0S
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BU of 5v0s by Molmil
Crystal structure of the ACT domain of prephenate dehydrogenase tyrA from Bacillus anthracis
Descriptor: CALCIUM ION, Prephenate dehydrogenase, SULFATE ION
Authors:Shabalin, I.G, Hou, J, Cymborowski, M.T, Otwinowski, Z, Kwon, K, Christendat, D, Gritsunov, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-02-28
Release date:2017-03-08
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain.
Febs J., 287, 2020
5YPP
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BU of 5ypp by Molmil
Crystal structure of IlvN.Val-1a
Descriptor: ACETATE ION, Acetolactate synthase isozyme 1 small subunit, DI(HYDROXYETHYL)ETHER, ...
Authors:Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B.
Deposit date:2017-11-02
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 58, 2019
5YPW
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BU of 5ypw by Molmil
Crystal structure of IlvN.Val-1b
Descriptor: Acetolactate synthase isozyme 1 small subunit, VALINE
Authors:Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B.
Deposit date:2017-11-03
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 58, 2019
4GO5
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BU of 4go5 by Molmil
The regulatory subunit of aspartate kinase from Mycobacterium tuberculosis
Descriptor: Aspartokinase
Authors:Yang, Q, Li, X.
Deposit date:2012-08-18
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural view of the regulatory subunit of aspartate kinase from Mycobacterium tuberculosis.
Protein Cell, 2, 2011
4GO7
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BU of 4go7 by Molmil
The regulatory subunit of aspartate kinase in complex with threonine from Mycobacterium tuberculosis
Descriptor: Aspartokinase, THREONINE
Authors:Yang, Q, Li, X.
Deposit date:2012-08-19
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural view of the regulatory subunit of aspartate kinase from Mycobacterium tuberculosis.
Protein Cell, 2, 2011
5UYY
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BU of 5uyy by Molmil
Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with L-tyrosine
Descriptor: Prephenate dehydrogenase, TYROSINE
Authors:Shabalin, I.G, Hou, J, Cymborowski, M.T, Kwon, K, Christendat, D, Gritsunov, A.O, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-02-24
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain.
Febs J., 287, 2020
2ZHO
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BU of 2zho by Molmil
Crystal structure of the regulatory subunit of aspartate kinase from Thermus thermophilus (ligand free form)
Descriptor: Aspartokinase
Authors:Yoshida, A, Tomita, T, Kuzuyama, T, Nishiyama, M.
Deposit date:2008-02-06
Release date:2009-02-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase from Thermus thermophilus
Febs J., 276, 2009
2DT9
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BU of 2dt9 by Molmil
Crystal structure of the regulatory subunit of aspartate kinase from Thermus flavus
Descriptor: ACETATE ION, Aspartokinase, THREONINE
Authors:Yoshida, A, Tomita, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M.
Deposit date:2006-07-11
Release date:2007-07-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase from Thermus thermophilus
Febs J., 276, 2009
2DTJ
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BU of 2dtj by Molmil
Crystal structure of regulatory subunit of aspartate kinase from Corynebacterium glutamicum
Descriptor: Aspartokinase, CITRIC ACID, THREONINE
Authors:Yoshida, A, Tomita, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M.
Deposit date:2006-07-12
Release date:2007-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural Insight into Concerted Inhibition of alpha(2)beta(2)-Type Aspartate Kinase from Corynebacterium glutamicum
J.Mol.Biol., 368, 2007
1Y7P
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BU of 1y7p by Molmil
1.9 A Crystal Structure of a Protein of Unknown Function AF1403 from Archaeoglobus fulgidus, Probable Metabolic Regulator
Descriptor: Hypothetical protein AF1403, ZINC ION, beta-D-ribopyranose
Authors:Zhang, R, Skarina, T, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-12-09
Release date:2005-02-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:1.9A crystal structure of a hypothetical protein AF1403 from Archaeoglobus fulgidus
To be Published
2FGC
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BU of 2fgc by Molmil
Crystal structure of Acetolactate synthase- small subunit from Thermotoga maritima
Descriptor: MAGNESIUM ION, acetolactate synthase, small subunit
Authors:Petkowski, J.J, Chruszcz, M, Zimmerman, M.D, Zheng, H, Cymborowski, M.T, Koclega, K.D, Kudritska, M, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-12-21
Release date:2006-02-07
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III small regulatory subunit.
Protein Sci., 16, 2007
2F1F
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BU of 2f1f by Molmil
Crystal structure of the regulatory subunit of acetohydroxyacid synthase isozyme III from E. coli
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Acetolactate synthase isozyme III small subunit, MAGNESIUM ION, ...
Authors:Kaplun, A, Vyazmensky, M, Barak, Z, Chipman, D.M, Shaanan, B.
Deposit date:2005-11-14
Release date:2006-01-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of the Regulatory Subunit of Acetohydroxyacid Synthase Isozyme III from Escherichia coli.
J.Mol.Biol., 357, 2006
6U60
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BU of 6u60 by Molmil
Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with NAD and L-tyrosine
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, Prephenate dehydrogenase, ...
Authors:Shabalin, I.G, Hou, J, Kutner, J, Grimshaw, S, Christendat, D, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-08-28
Release date:2019-09-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain.
Febs J., 287, 2020
3S1T
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BU of 3s1t by Molmil
Structure of the regulatory domain of aspartokinase (Rv3709c; AK-beta) in complex with threonine from Mycobacterium tuberculosis
Descriptor: Aspartokinase, SULFATE ION, THREONINE
Authors:Schuldt, L, Mueller-Dieckmann, J, Weiss, M.S.
Deposit date:2011-05-16
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:High-resolution X-ray structure of the regulatory domain of the mycobacterial aspartokinase in complex with threonine
To be Published
2RE1
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BU of 2re1 by Molmil
Crystal structure of aspartokinase alpha and beta subunits
Descriptor: Aspartokinase, alpha and beta subunits, CALCIUM ION
Authors:Chang, C, Li, H, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-09-25
Release date:2007-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of aspartokinase alpha and beta subunits.
To be Published
6DZS
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BU of 6dzs by Molmil
Mycobacterial homoserine dehydrogenase ThrA in complex with NADP
Descriptor: Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Chaton, C.T, Rodriguez, E.S, Korotkov, K.V.
Deposit date:2018-07-05
Release date:2018-07-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structure of mycobacterial homoserine dehydrogenase ThrA
To be Published
3L76
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BU of 3l76 by Molmil
Crystal Structure of Aspartate Kinase from Synechocystis
Descriptor: Aspartokinase, LYSINE, SULFATE ION, ...
Authors:Robin, A, Cobessi, D, Curien, G, Robert-Genthon, M, Ferrer, J.-L, Dumas, R.
Deposit date:2009-12-28
Release date:2010-06-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:A new mode of dimerization of allosteric enzymes with ACT domains revealed by the crystal structure of the aspartate kinase from Cyanobacteria
J.Mol.Biol., 399, 2010
5DEN
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BU of 5den by Molmil
The First Structure of a Full-Length Mammalian Phenylalanine Hydroxylase Reveals the Architecture of an Auto-inhibited Tetramer
Descriptor: FE (III) ION, Phenylalanine-4-hydroxylase
Authors:Arturo, E.C, Loll, P.J, Jaffe, E.K.
Deposit date:2015-08-25
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer.
Proc.Natl.Acad.Sci.USA, 113, 2016
3TVI
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BU of 3tvi by Molmil
Crystal structure of Clostridium acetobutylicum aspartate kinase (CaAK): An important allosteric enzyme for industrial amino acids production
Descriptor: ASPARTIC ACID, Aspartokinase, LYSINE
Authors:Manjasetty, B.A, Chance, M.R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2011-09-20
Release date:2011-11-09
Last modified:2021-02-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of Clostridium acetobutylicum Aspartate kinase (CaAK): An important allosteric enzyme for amino acids production.
Biotechnol Rep (Amst), 3, 2014
2HMF
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BU of 2hmf by Molmil
Structure of a Threonine Sensitive Aspartokinase from Methanococcus jannaschii Complexed with Mg-ADP and Aspartate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ASPARTIC ACID, MAGNESIUM ION, ...
Authors:Faehnle, C.R, Viola, R.E.
Deposit date:2006-07-11
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The initial step in the archaeal aspartate biosynthetic pathway catalyzed by a monofunctional aspartokinase.
Acta Crystallogr.,Sect.F, 62, 2006
3W7B
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BU of 3w7b by Molmil
Crystal structure of formyltetrahydrofolate deformylase from Thermus thermophilus HB8
Descriptor: Formyltetrahydrofolate deformylase
Authors:Sampei, G, Yanagida, Y, Ogata, N, Kusano, M, Terao, K, Kawai, H, Fukai, Y, Kanagawa, M, Inoue, Y, Baba, S, Kawai, G.
Deposit date:2013-02-28
Release date:2014-01-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structures and reaction mechanisms of the two related enzymes, PurN and PurU
J.Biochem., 154, 2013

 

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數據於2024-04-17公開中

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