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6OYL
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BU of 6oyl by Molmil
The structure of the PP2A B56 subunit KIF4A complex
Descriptor: Chromosome-associated kinesin KIF4A, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Authors:Wang, X, Page, R, Peti, W.
Deposit date:2019-05-14
Release date:2020-03-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment.
Elife, 9, 2020
5SWF
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BU of 5swf by Molmil
The structure of the PP2A B56 subunit double phosphorylated BubR1 complex
Descriptor: Double phosphorylated BubR1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Authors:Page, R, Wang, X, Bajaj, R, Peti, W.
Deposit date:2016-08-08
Release date:2016-11-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.818 Å)
Cite:Expanding the PP2A Interactome by Defining a B56-Specific SLiM.
Structure, 24, 2016
5SW9
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BU of 5sw9 by Molmil
The structure of the PP2A B56 subunit RepoMan complex
Descriptor: RepoMan, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Authors:Page, R, Wang, X, Bajaj, R, Peti, W.
Deposit date:2016-08-08
Release date:2016-11-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.846 Å)
Cite:Expanding the PP2A Interactome by Defining a B56-Specific SLiM.
Structure, 24, 2016
5JJA
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BU of 5jja by Molmil
Crystal structure of a PP2A B56gamma/BubR1 complex
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Authors:Wang, Z, Wang, J, Rao, Z, Xu, W.
Deposit date:2016-04-22
Release date:2016-07-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization.
Protein Cell, 7, 2016
5K6S
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BU of 5k6s by Molmil
The structure of the PP2A B56 subunit BubR1 complex
Descriptor: BubR1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Authors:Page, R, Wang, X, Bajaj, R, Peti, W.
Deposit date:2016-05-25
Release date:2016-12-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.794 Å)
Cite:Expanding the PP2A Interactome by Defining a B56-Specific SLiM.
Structure, 24, 2016
2JAK
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BU of 2jak by Molmil
Human PP2A regulatory subunit B56g
Descriptor: SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM
Authors:Magnusdottir, A, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Johansson, I, Karlberg, T, Kotenyova, T, Lundgren, S, Moche, M, Nilsson, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Upsten, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Nordlund, P.
Deposit date:2006-11-29
Release date:2006-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structure of the Pp2A Regulatory Subunit B56 Gamma: The Remaining Piece of the Pp2A Jigsaw Puzzle.
Proteins, 74, 2009
6VRO
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BU of 6vro by Molmil
The structure of the PP2A B56 subunit AIM1 complex
Descriptor: Beta/gamma crystallin domain-containing protein 1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Authors:Wang, X, Page, R, Peti, W.
Deposit date:2020-02-08
Release date:2020-03-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment.
Elife, 9, 2020
7SOY
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BU of 7soy by Molmil
The structure of the PP2A-B56gamma1 holoenzyme-PME-1 complex
Descriptor: Isoform Gamma-1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Protein phosphatase methylesterase 1, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
Authors:Li, Y, Balakrishnan, V.K, Rowse, M, Novikova, I.V, Xing, Y.
Deposit date:2021-11-01
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition.
Elife, 11, 2022
6NTS
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BU of 6nts by Molmil
Protein Phosphatase 2A (Aalpha-B56alpha-Calpha) holoenzyme in complex with a Small Molecule Activator of PP2A (SMAP)
Descriptor: MANGANESE (II) ION, N-[(1R,2R,3S)-2-hydroxy-3-(10H-phenoxazin-10-yl)cyclohexyl]-4-(trifluoromethoxy)benzene-1-sulfonamide, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform, ...
Authors:Huang, W, Taylor, D.
Deposit date:2019-01-30
Release date:2020-05-06
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Selective PP2A Enhancement through Biased Heterotrimer Stabilization.
Cell, 181, 2020
3FGA
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BU of 3fga by Molmil
Structural Basis of PP2A and Sgo interaction
Descriptor: MANGANESE (II) ION, MICROCYSTIN-LR, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ...
Authors:Xu, Z, Xu, W.
Deposit date:2008-12-05
Release date:2009-09-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and function of the PP2A-shugoshin interaction
Mol.Cell, 35, 2009
8U89
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BU of 8u89 by Molmil
The structure of the PP2A-B56Delta holoenzyme mutant - E197K
Descriptor: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
Authors:Wu, C.G, Xing, Y.
Deposit date:2023-09-16
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U1X
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BU of 8u1x by Molmil
The structure of the PP2A-B56Delta holoenzyme mutant - E197K
Descriptor: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
Authors:Wu, C.G, Xing, Y.
Deposit date:2023-09-04
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations.
Proc.Natl.Acad.Sci.USA, 121, 2024
2IAE
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BU of 2iae by Molmil
Crystal structure of a protein phosphatase 2A (PP2A) holoenzyme.
Descriptor: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
Authors:Cho, U.S, Xu, W.
Deposit date:2006-09-07
Release date:2006-12-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
Nature, 445, 2007
6TOQ
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BU of 6toq by Molmil
Crystal structure of a PP2A B56y/HTLV-1 integrase complex
Descriptor: Pol protein, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Authors:Minnell, J.J, Barski, M.S, Maertens, G.N.
Deposit date:2019-12-11
Release date:2020-10-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.164 Å)
Cite:Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56 gamma.
Nat Commun, 11, 2020
2NPP
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BU of 2npp by Molmil
Structure of the Protein Phosphatase 2A Holoenzyme
Descriptor: MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ...
Authors:Xu, Y, Chen, Y, Xing, Y, Chao, Y, Shi, Y.
Deposit date:2006-10-28
Release date:2006-12-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the protein phosphatase 2A holoenzyme
Cell(Cambridge,Mass.), 127, 2006
2NYL
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BU of 2nyl by Molmil
Crystal structure of Protein Phosphatase 2A (PP2A) holoenzyme with the catalytic subunit carboxyl terminus truncated
Descriptor: MANGANESE (II) ION, Protein phosphatase 2, regulatory subunit A (PR 65), ...
Authors:Xing, Y, Xu, Y, Chen, Y, Chao, Y, Lin, Z, Shi, Y.
Deposit date:2006-11-20
Release date:2006-12-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of the Protein Phosphatase 2A Holoenzyme.
Cell(Cambridge,Mass.), 127, 2006
2NYM
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BU of 2nym by Molmil
Crystal Structure of Protein Phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit
Descriptor: MANGANESE (II) ION, Protein phosphatase 2, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ...
Authors:Chen, Y, Xing, Y, Xu, Y, Chao, Y, Lin, Z, Jeffrey, P.D, Shi, Y.
Deposit date:2006-11-21
Release date:2006-12-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure of the Protein Phosphatase 2A Holoenzyme.
Cell(Cambridge,Mass.), 127, 2006
6VOY
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BU of 6voy by Molmil
Cryo-EM structure of HTLV-1 instasome
Descriptor: DNA (25-MER), DNA (5'-D(P*AP*CP*AP*CP*AP*CP*TP*TP*GP*AP*CP*TP*AP*GP*GP*GP*TP*G)-3'), DNA-binding protein 7d, ...
Authors:Bhatt, V, Shi, K, Sundborger, A, Aihara, H.
Deposit date:2020-02-01
Release date:2020-07-01
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of host protein hijacking in human T-cell leukemia virus integration.
Nat Commun, 11, 2020
7OUF
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BU of 7ouf by Molmil
Structure of the STLV intasome:B56 complex bound to the strand-transfer inhibitor XZ450
Descriptor: 4-azanyl-~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-6-[3-(dimethylamino)-3-oxidanylidene-propyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridine-3-carboxamide, DNA (5'-D(*AP*CP*TP*GP*TP*GP*TP*TP*TP*GP*GP*CP*GP*CP*TP*TP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*AP*AP*GP*CP*GP*CP*CP*AP*AP*AP*CP*AP*CP*A)-3'), ...
Authors:Barski, M.S, Ballandras-Colas, A, Cronin, N.B, Pye, V.E, Cherepanov, P, Maertens, G.N.
Deposit date:2021-06-11
Release date:2021-08-18
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures.
Nat Commun, 12, 2021
7PEL
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BU of 7pel by Molmil
CryoEM structure of simian T-cell lymphotropic virus intasome in complex with PP2A regulatory subunit B56 gamma
Descriptor: DNA (5'-D(*AP*CP*TP*GP*TP*GP*TP*TP*TP*GP*GP*CP*GP*CP*TP*TP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*AP*AP*GP*CP*GP*CP*CP*AP*AP*AP*CP*AP*CP*A)-3'), Isoform 3 of PC4 and SFRS1-interacting protein,Isoform Gamma-2 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ...
Authors:Barski, M, Pye, V.E, Nans, A, Cherepanov, P, Maertens, G.N.
Deposit date:2021-08-10
Release date:2021-08-25
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56gamma.
Nat Commun, 11, 2020
7OUG
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BU of 7oug by Molmil
STLV-1 intasome:B56 in complex with the strand-transfer inhibitor raltegravir
Descriptor: DNA (5'-D(*AP*CP*TP*GP*TP*GP*TP*TP*TP*GP*GP*CP*GP*CP*TP*TP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*AP*AP*GP*CP*GP*CP*CP*AP*AP*AP*CP*AP*CP*A)-3'), Integrase, ...
Authors:Barski, M.S, Ballandras-Colas, A, Cronin, N.B, Pye, V.E, Cherepanov, P, Maertens, G.N.
Deposit date:2021-06-11
Release date:2021-08-18
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures.
Nat Commun, 12, 2021
7OUH
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BU of 7ouh by Molmil
Structure of the STLV intasome:B56 complex bound to the strand-transfer inhibitor bictegravir
Descriptor: Bictegravir, DNA (5'-D(*AP*CP*TP*GP*TP*GP*TP*TP*TP*GP*GP*CP*GP*CP*TP*TP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*AP*AP*GP*CP*GP*CP*CP*AP*AP*AP*CP*AP*CP*A)-3'), ...
Authors:Barski, M.S, Ballandras-Colas, A, Cronin, N.B, Pye, V.E, Cherepanov, P, Maertens, G.N.
Deposit date:2021-06-11
Release date:2021-08-18
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures.
Nat Commun, 12, 2021

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數據於2024-03-27公開中

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