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7YQH
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BU of 7yqh by Molmil
Cryo-EM structure of 8-subunit Smc5/6
Descriptor: DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Non-structural maintenance of chromosome element 3, ...
Authors:Qian, L, Jun, Z, Xiang, Z, Tong, C, Zhaoning, W, Duo, J, Zhenguo, C, Lanfeng, W.
Deposit date:2022-08-07
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Cryo-EM structure of 8-subunit Smc5/6
To Be Published
7YMD
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BU of 7ymd by Molmil
Cryo-EM structure of Nse1/3/4
Descriptor: Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosome element 4, Non-structural maintenance of chromosomes element 1
Authors:Qian, L, Jun, Z, Zhenguo, C, Lanfeng, W.
Deposit date:2022-07-28
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (4.176 Å)
Cite:Cryo-EM structure of Nse1/3/4
To Be Published
7UOA
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BU of 7uoa by Molmil
MAGEA4-MTP1 linear peptide complex
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MTP-1, ...
Authors:Williams, R.S, Tumbale, P.S.
Deposit date:2022-04-12
Release date:2022-09-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Discovery and Structural Basis of the Selectivity of Potent Cyclic Peptide Inhibitors of MAGE-A4.
J.Med.Chem., 65, 2022
7TVE
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BU of 7tve by Molmil
ATP and DNA bound SMC5/6 core complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (68-MER), DNA (78-MER), ...
Authors:Yu, Y, Patel, D.J.
Deposit date:2022-02-04
Release date:2022-06-22
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes.
Proc.Natl.Acad.Sci.USA, 119, 2022
7QCD
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BU of 7qcd by Molmil
CryoEM structure of the Smc5/6-holocomplex (composite structure)
Descriptor: E3 SUMO-protein ligase MMS21, Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosome element 4, ...
Authors:Hallett, S.T, Oliver, A.W.
Deposit date:2021-11-23
Release date:2022-09-21
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Cryo-EM structure of the Smc5/6 holo-complex.
Nucleic Acids Res., 50, 2022
7DG2
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BU of 7dg2 by Molmil
Nse1-Nse3-Nse4 complex
Descriptor: ACETATE ION, GLYCEROL, MAGE domain-containing protein, ...
Authors:Cho, Y, Jo, A.
Deposit date:2020-11-10
Release date:2021-05-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure Basis for Shaping the Nse4 Protein by the Nse1 and Nse3 Dimer within the Smc5/6 Complex.
J.Mol.Biol., 433, 2021
6WJH
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BU of 6wjh by Molmil
Crystal structure of MAGE-A11 bound to the PCF11 degron
Descriptor: Fusion protein of PCF11 and MAGE-A11
Authors:Miller, D.J, Huang, X.
Deposit date:2020-04-13
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.
Nat Commun, 11, 2020
6R7T
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BU of 6r7t by Molmil
Crystal Structure of human Melanoma-associated antigen B1 (MAGEB1) in complex with nanobody
Descriptor: Melanoma-associated antigen B1, anti MAGEB1 nanobody
Authors:Ye, M, Newman, J, Pike, A.C.W, Burgess-Brown, N, Cooper, C.D.O, Bountra, C, Arrowsmith, C, Edwards, A, Gileadi, O, von Delft, F.
Deposit date:2019-03-29
Release date:2019-05-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.682 Å)
Cite:Crystal Structure of Melanoma-associated antigen B1 (MAGEB1) in complex with nanobody
To Be Published
5WY5
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BU of 5wy5 by Molmil
Crystal structure of MAGEG1 and NSE1 complex
Descriptor: MAGNESIUM ION, Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ...
Authors:Yang, M, Gao, J.
Deposit date:2017-01-11
Release date:2017-05-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Mage-Ring Protein Complexes Comprise A Family Of E3 Ubiquitin Ligases.
Mol.Cell, 39, 2010
5HVQ
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BU of 5hvq by Molmil
Alternative model of the MAGE-G1 NSE-1 complex
Descriptor: Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ZINC ION
Authors:Newman, J.A, Cooper, C.D.O, Roos, A.K, Aitkenhead, H, Oppermann, U.C.T, Cho, H.J, Osman, R, Gileadi, O.
Deposit date:2016-01-28
Release date:2016-10-26
Method:X-RAY DIFFRACTION (2.923 Å)
Cite:Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Plos One, 11, 2016
4V0P
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BU of 4v0p by Molmil
Crystal structure of the MAGE homology domain of human MAGE-A3
Descriptor: MELANOMA-ASSOCIATED ANTIGEN 3
Authors:Newman, J.A, Aitkenhead, H, Cooper, C.D.O, Pinkas, D.M, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2014-09-17
Release date:2014-10-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Plos One, 11, 2016
2WA0
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BU of 2wa0 by Molmil
Crystal structure of the human MAGEA4
Descriptor: MELANOMA-ASSOCIATED ANTIGEN 4
Authors:Roos, A.K, Cooper, C.D.O, Ugochukwu, E, W Yue, W, Berridge, G, Elkins, J.M, Pike, A.C.W, Bray, J, Filippakopoulos, P, Muniz, J, Chaikuad, A, Burgess-Brown, N, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, von Delft, F, Gileadi, O, Oppermann, U.
Deposit date:2009-01-31
Release date:2009-03-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Plos One, 11, 2016

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數據於2024-04-17公開中

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